Cellular membrane protection against reactive oxygen species by Terminalia arjuna and its active component baicalein

Journal of Clinical Biochemistry and Nutrition

Volumn 39, Issue 2, 2006, Pages 75-87

  Tilak, Jai C ^a   Devasagayam, Thomas P A ^a   Adhikari, Soumyakanti ^a   Lele, Ramachandra D ^b   Kon, Tatsuya ^c   Handa, Osamu ^d   Naito, Yuji ^d   Yoshikawa, Toshikazu ^e  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

^b JASLOK HOSPITAL AND RESEARCH CENTRE   (India)

^c Central Research Development Laboratory Fancl Corporation   (Japan)

^d KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^e KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Electron spin resonance; Lipid peroxidation; Pulse radiolysis; Singlet oxygen; Superoxide radical

Indexed keywords

BAICALEIN; REACTIVE OXYGEN METABOLITE; TERMINALIA ARJUNA EXTRACT;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; DRUG ACTIVITY; DRUG MECHANISM; LIPID PEROXIDATION; LIVER MITOCHONDRION; MOUSE; NONHUMAN; OXIDATION; RADIATION; TERMINALIA;

TERMINALIA ARJUNA;

EID: 33748947814     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.39.75     Document Type: Article

References (46)

1. Miller, A.L.: Botanical influences on cardiovascular disease. Altern. Med. Rev., 3, 422-431, 1998.
2. Kaur, K., Arora, S., Kumar, S., and Nagpal, A.: Modulatory effect of phenolic fractions of Terminalia arjuna on the mutagenicity in Ames assay. J. Environ. Pathol. Toxicol. Oncol., 21, 45-56, 2002.
3. Gupta, R., Singhal, S., Goyle, A., and Sharma, V.N.: Antioxidant and hypocholesterolaemic effects of Terminalia arjuna tree-bark powder: a randomised placebo-controlled trial. J. Assoc. Physicians India, 49, 231-235, 2001.
4. Sharma, P.N., Shoeb, A., Kapil, R.S., and Popli, S.P.: Arjunolone: a new flavone from stem bark of Terminalia arjuna. Indian J. Chem., 49, 231-235, 1982.
5. Huang, H.C., Wang, H.R., and Hsieh, L.M.: Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell. Eur. J. Pharmacol., 251, 91-93, 1994.
6. Motoo, Y. and Sawabu, N.: Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell lines. Cancer Lett., 86, 91-95, 1994.
7. Lee, B.H., Lee, S.J., Kang, T.H., Kim, D.H., Sohn, D.H., Ko, G.I., and Kim, Y.C.: Baicalein: an in vitro antigenotoxic compound from Scutellaria baicalensis. Planta. Med., 66, 70-71, 2000.
8. Gao, D., Sakurai, K., Katoh, M., Chen, J., and Ogiso, T.: Inhibition of microsomal lipid peroxidation by baicalein: a possible formation of an iron-baicalein complex. Biochem. Mol. Biol. Int., 39, 215-225, 1996.
9. Gao, Z., Huang, K., Yang, X., and Xu, H.: Free radical scavenging and antioxidant activities of flavonoids extracted from the radix of Scutellaria baicalensis Georgi. Biochim. Biophys. Acta., 1472, 643-650, 1999.
10. Shieh, D.E., Liu, L.T., and Lin, C.C.: Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res., 20, 2861-2865, 2000.
11. Chang, W.S., Lee, Y.J., Lu, F.J., and Chiang, H.C.: Inhibitory effects of flavonoids on xanthine oxidase. Anticancer Res., 13, 2165-2170, 1993.
12. Shao, Z.H., Vanden Hoek, T.L., Qin, Y., Becker, L.B., Schumacker, P.T., Li, C.Q., Dey, L., Barth, E., Halpern, H., Rosen, G.M., and Yuan, C.S.: Baicalein attenuates oxidant stress in cardiomyocytes. Am. J. Physiol. Heart Circ. Physiol., 282, H999-H1006, 2002.
13. Yoshikawa, T., Toyokuni, S., Yamamoto, Y., and Naito, Y.: Free Radicals in Chemistry, Biology, and Medicine. OICA International, London, 2000.
14. Wallace, S.S.: AP endonucleases and DNA glycosylases that recognize oxidative DNA damage. Environ. Mol. Mutagen., 12, 431-477, 1988.
15. Wakui, Y., Yanagisawa, E., Ishibashi, E., Matsuzaki, Y., Takeda, S., Sasaki, H., Aburada, M., and Oyama, T.: Determination of baicalin and baicalein in rat plasma by high-performance liquid chromatography with electrochemical detection. J. Chromatogr., 575, 131-136, 1992.
16. Lai, M.Y., Hsiu, S.L., Tsai, S.Y., Hou, Y.C., and Chao, P.D.: Comparison of metabolic pharmacokinetics of baicalin and baicalein in rats. J. Pharm. Pharmacol., 55, 205-209, 2003.
17. Akao, T., Kawabata, K., Yanagisawa, E., Ishihara, K., Mizuhara, Y., Wakui, Y., Sakashita, Y., and Kobashi, K.: Baicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form. J. Pharm. Pharmacol., 52, 1563-1568, 2000.
18. Kontush, A., Spranger, T., Reich, A., Djahansouzi, S., Karten, B., Braesen, J.H., Finckh, B., Kohlschutter, A., and Beisiegel, U.: Whole plasma oxidation assay as a measure of lipoprotein oxidizability. Biofactors, 6, 99-109, 1997.
19. Spencer, J.P., Chowrimootoo, G., Choudhury, R., Debnam, E.S., Srai, S.K., and Rice-Evans, C.: The small intestine can both absorb and glucuronidate luminal flavonoids. FEBS Lett., 458, 224-230, 1999.
20. Devasagayam, T.P.: Low level of lipid peroxidation in newborn rats. Possible factors for resistance in hepatic microsomes. FEBS Lett., 199, 203-207, 1986.
21. Lowry, O.H., Rosenbrough, N.J., Farr, A.L., and Randall, R.J.: Protein measurement with the folin phenol reagent. J. Biol. Chem., 193, 265-275, 1951.
22. Das, K., Samanta, L., and Chainy, G.B.N.: A modified spectrophotometric assay of superoxide dismutase using nitrite formation by superoxide radicals. Ind. J. Biochem. Biophys., 237, 201-204, 2000.
23. Kamat, J.P., Boloor, K.K., and Devasagayam, T.P.: Chlorophyllin as an effective antioxidant against membrane damage in vitro and ex vivo. Biochim. Biophys. Acta., 1487, 113-127, 2000.
24. Buege, J.A. and Aust, S.D.: Microsomal lipid peroxidation. Methods Enzymol., 52, 302-310, 1978.
25. Hermes-Lima, M., Willmore, W.G., and Storey, K.B.: Quantification of lipid peroxidation in tissue extracts based on Fe(III) xylenol orange complex formation. Free Radic. Biol. Med., 19, 271-280, 1995.
26. Shao, Z.H., Xie, J.T., Vanden Hoek, T.L., Mehendale, S., Aung, H., Li, C.Q., Qin, Y., Schumacker, P.T., Becker, L.B., and Yuan, C.S.: Antioxidant effects of American ginseng berry extract in cardiomyocytes exposed to acute oxidant stress. Biochim. Biophys. Acta., 1670, 165-171, 2004.
27. Schwarz, M.A., Lazo, J.S., Yalowich, J.C., Reynolds, I., Kagan, V.E., Tyurin, V., Kim, Y.M., Watkins, S.C., and Pitt, B.R.: Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity. J. Biol. Chem., 269, 15238-15243, 1994.
28. Zang, L.Y., Stone, K., and Pryor, W.A.: Detection of free radicals in aqueous extracts of cigarette tar by electron spin resonance. Free Radic. Biol. Med., 19, 161-167, 1995.
29. Kumagai, Y., Arimoto, T., Shinyashiki, M., Shimojo, N., Nakai, Y., Yoshikawa, T., and Sagai, M.: Generation of reactive oxygen species during interaction of diesel exhaust particle components with NADPH-cytochrome P450 reductase and involvement of the bioactivation in the DNA damage. Free Radic. Biol. Med., 22, 479-487, 1997.
30. Lion, Y., Delmelle, M., and van de Vorst, A.: New method of detecting singlet oxygen production. Nature, 263, 442-443, 1976.
31. He, Y.Y., An, J.Y., and Jiang, L.J.: Electric magnetic resonance and spectrophotometry evidence on the photodynamic activity of a new perylenequinonoid pigment. J. Photochem. Photobiol. B., 50, 166-173, 1999.
32. Mukherjee, T.: Some recent studies of molecular dynamics at BARC, in Atomic, Molecular and Cluster Physics, ed. By Ahmed, S.A., Narosa Publishers, New Delhi, pp. 299-316, 1997.
33. Buxton, G.V. and Stuart, C.R.: Re-evaluation of the thiocyanate dosimeter for pulse radiolysis. J. Chem. Soc. Faraday Trans., 91, 1995.
34. Li, B.Q., Fu, T., Gong, W.H., Dunlop, N., Kung, H., Yan, Y., Kang, J., and Wang, J.M.: The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines. Immunopharmacology, 49, 295-306, 2000.
35. Ikemoto, S., Sugimura, K., Yoshida, N., Yasumoto, R., Wada, S., Yamamoto, K., and Kishimoto, T.: Antitumor effects of Scutellariae radix and its components baicalein, baicalin, and wogonin on bladder cancer cell lines. Urology, 55, 951-955, 2000.
36. Moan, J.: On the dissusion, length of singlet oxygen in cells and tissues. J. Photochem. Photobiol. B., 6, 343-347, 1990.
37. Piette, J.: Biological consequences associated with DNA oxidation mediated by singlet oxygen. J. Photochem. Photobiol. B., 11, 241-260, 1991.
38. Safari, M.R. and Sheikh, N.: Effects of flavonoids on the susceptibility of low-density lipoprotein to oxidative modification. Prostaglandins Leukot. Essent. Fatty Acids, 69, 73-77, 2003.
39. Nanni, E.J., Stallings, M.D., and Sawyer, D.T.: Does superoxide ion oxidize catechol, a-tocopherol and ascorbic acid by direct electron transfer? J. Am. Chem. Soc., 102, 4481-4485, 1971.
40. Takahashi, M. and Asada, K.: A flash-photometric method for determination of reactivity of superoxide: application to superoxide dismutase assay. J. Biochem. (Tokyo), 91, 889-896, 1982.
41. Naik, D.B. and Moorthy, P.N.: Reaction of pyridine-3-ol with pulse radiolytically generated reducing species. J. Chem. Soc. Perkin. Trans., 2, 705-709, 1990.
42. Zhu, M., Rajamani, S., Kaylor, J., Han, S., Zhou, F., and Fink, A.L.: The flavonoid baicalein inhibits fibrillation of alpha-synuclein and disaggregates existing fibrils. J. Biol. Chem., 279, 26846-26857, 2004.
43. Heo, H.J., Kim, D.O., Choi, S.J., Shin, D.H., and Lee, C.Y.: Potent Inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid beta protein-induced neurotoxicity. J. Agric. Food Chem., 52, 4128-4132, 2004.
44. Taira, Z., Yabe, K., Hamaguchi, Y., Hirayama, K., Kishimoto, M., Ishida, S., and Ueda, Y.: Effects of Sho-saiko-to extract and its components, Baicalin, baicalein, glycyrrhizin and glycyrrhetic acid, on pharmacokinetic behavior of salicylamide in carbon tetrachloride intoxicated rats. Food Chem. Toxicol., 42, 803-807, 2004.
45. Li, Y.C., Tyan, Y.S., Kuo, H.M., Chang, W.C., Hsia, T.C., and Chung, J.G.: Baicalein induced in vitro apoptosis undergo caspases activity in human promyelocytic leukemia HL-60 cells. Food Chem. Toxicol., 42, 37-43, 2004.
46. Kirtikar, K.R., and Basu, B.D.: Indian Medicinal Plants, Vol. I & II, Blatter, E., Cauis, J.R., Mhaskar, K.S., Basu, L.M. Allahabad, 1984.