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A diastereomeric mixture of 4 was synthesized as described in ref 3a. A diastereomeric mixture of 8 was generated by modifying the Birch reduction conditions, i.e., removal of NHs, as described in ref 3a.
-
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32
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33748928857
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note
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γ-Alkylation of amide enolates derived from Birch reduction has previously been reported, see ref 3a and references therein.
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