A practical method for enantioselective synthesis of all-carbon quaternary stereogenic centers through NHC-Cu-catalyzed conjugate additions of alkyl- and arylzinc reagents to β-substituted cyclic enones

Journal of the American Chemical Society

Volumn 128, Issue 22, 2006, Pages 7182-7184

  Lee, Kang Sang ^a   Brown, M Kevin ^a   Hird, Alexander W ^a   Hoveyda, Amir H ^a  

^a BOSTON COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENYL GROUP; BORONIC ACID DERIVATIVE; CARBONYL DERIVATIVE; COPPER COMPLEX; CYCLOHEXANONE; OXAZOLIDINONE DERIVATIVE; PHOSPHINE; REAGENT; RHODIUM; ZINC;

ADDITION REACTION; ALKYLATION; ARTICLE; CATALYSIS; CHEMICAL BOND; CHIRALITY; CONJUGATE; CROSS COUPLING REACTION; ENANTIOSELECTIVITY; SOLUBILITY; SYNTHESIS;

ALKANES; ALKYLATION; CARBON; CATALYSIS; COPPER; CYCLIZATION; KETONES; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; STEREOISOMERISM; ZINC;

EID: 33744926164     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja062061o     Document Type: Article

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