Isolation, structure elucidation, total synthesis, and evaluation of new natural and synthetic ceramides on human SK-MEL-1 melanoma cells

Journal of Medicinal Chemistry

Volumn 49, Issue 19, 2006, Pages 5830-5839

  León, Francisco ^a,b   Brouard, Ignacio ^a   Rivera, Augusto ^d   Torres, Fernando ^c   Rubio, Sara ^c   Quintana, José ^c   Estévez, Francisco ^c   Bermejo, Jaime ^a  

^a INSTITUTO DE PRODUCTOS NATURALES Y AGROBIOLOGÍA   (Spain)

^b Madrid Spain   (Spain)

^c UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

^d UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2',3' DIACETOXYEICOSANOYLAMINO) 1,3,4 TRIACETOXYDOCOSANE; ACETIC ACID DERIVATIVE; CERAMIDE; DNA FRAGMENT; METHANOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 8; PROCASPASE 9; TRAMETENAMIDE A; TRAMETENAMIDE B; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL STRAIN SK MEL 1; CHEMICAL MODIFICATION; CONTROLLED STUDY; DIASTEREOISOMER; DNA STRAND BREAKAGE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG SYNTHESIS; ENZYME DEGRADATION; FRUITING BODY; FUNGUS; HUMAN; HUMAN CELL; MELANOMA CELL; NONHUMAN; PROTEIN PROCESSING; SPECTROSCOPY; STEREOCHEMISTRY; STRUCTURE ANALYSIS; TRAMETES MENZIESII; TUMOR CELL LINE;

CELL LINE, TUMOR; CERAMIDES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MELANOMA; POLYPORACEAE; STEREOISOMERISM;

EID: 33748861953     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0605334     Document Type: Article

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