A preliminary ecotoxicity study of pharmaceuticals in the marine environment

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 69, Issue 21, 2006, Pages 1959-1970

  Choong, Amy Mei Fun ^a   Teo, Serena Lay Ming ^a   Leow, Jo Lene ^a   Koh, Hwee Ling ^a   Ho, Paul Chi Lui ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIZINE; FRESH WATER; PROCHLORPERAZINE; SEA WATER;

BARNACLE; CHEMICAL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG INDUSTRY; ECOTOXICITY; MARINE ENVIRONMENT; NONHUMAN; PRIORITY JOURNAL; SEA;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIZINE; ENVIRONMENTAL POLLUTANTS; LARVA; LIGHT; MOLECULAR STRUCTURE; OCEANS AND SEAS; PROCHLORPERAZINE; SEAWATER; THORACICA; TIME FACTORS;

BALANUS AMPHITRITE; INVERTEBRATA; THORACICA; VERTEBRATA;

EID: 33748859078     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390600751371     Document Type: Conference Paper

References (21)

1. Batley, G. 1996. The distribution and fate of tributyltin in the marine environment. In Tributyltin: Case study of an environmental contaminant, ed. S J de Mora, pp. 139-166. Cambridge: Cambridge University Press.
2. Burton, E. D., Phillips, I. R., and Hawker, D. W. 2005. In situ partitioning of butylin compounds in estuarine sediments. Chemosphere 59:585-592.
3. Buser, H. R., Muller, M. D., and Theobald, N. 1998. Occurrence of the pharmaceutical drug clofibric acid and the herbicide mecoprop in various Swiss lakes and in the North Sea. Environ. Sci. Technol. 32:188-192.
4. Cleuvers, M. 2004. Mixture toxicity of the anti-inflammatory drugs diclofenac, ibuprofen, naproxen, and acetylsalicylic acid. Ecotoxicol. Environ Safety 59:309-315.
5. Emmanuel, E., Keck, G., Blanchard, J. M., Vermande, P., and Perrodin, Y. 2004. Toxicological effects of disinfections using sodium hypochlorite on aquatic organisms and its contribution to AOX formation in hospital wastewater. Environ Int. 30:891-900.
6. Erlandsson, B., and Matsson, S. 1978. Medically used radionuclides in sewage sludge. Water Air Soil Pollut. 2:199-206.
7. Fong, P. P. 2001. Antidepressants in aquatic organisms: a wide range of effects. In Pharmacueticals and personal care products in the environment: Scientific and regulatory issues, eds. C. G. Daughton and T. L. Jones-Lepp, pp. 264-281. Washington, DC: American Chemical Society.
8. Fong, P. P., Huminski, P. T., and D'Urso, L. M. 1998. Induction and potentiation of parturition in fingernail clams (Sphaerium striatinum) by selective serotonin reuptake signaling. J. Exp. Zool. 280: 260-264.
9. Heberer, T. 2002. Tracking persistent pharmaceutical residues from municipal sewage to drinking water. J. Hydrol. 266:175-189.
10. Heberer, T., Reddersen, K., and Mechlinski, A. 2002. From municipal sewage to drinking water: fate and removal of pharmaceutical residues in the aquatic environment in urban areas. Water Sci. Technol. 46(3):81-88.
11. Kimura, K., Toshima, S., Amy, G., and Watanabe. Y. 2004. Rejection of neutral endocrine disrupting compounds (EDCs) and pharmaceutical active compounds (PhACs) by RO membranes. J. Membr. Sci. 245:71-78.
12. Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., and Buxton, H. T. 2002. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams. 1999-2000: A national reconnaissance. Environ. Sci. Technol. 36:1202-1211.
13. Kümmerer, K. 2001. Drugs in the environment: Emission of drugs, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources-A review. Chemosphere 45:957-969.
14. Kümmerer, K., Meyer, M., and Steger-Hartmann, T. 1997. Biodegradability of the anti-tumour agent ifosfamide and its occurrence in hospital effluents and communal sewage. Water Res. 31:2705-2710.
15. Libermann, H. R. 1983. Estimating LD50 using the probit technique: a basic computer program. Drug Chem. Toxicol. 6:111-116.
16. Nunes, B., Carvalho, F., and Guilhermino, L. 2004. Acute and chronic effects of clofibrate and clofibric acid on the enzymes acetylcholinesterase, lactate dehydrogenase and catalase of the mosquitofish, Gambusia holbrooki. Chemosphere 57:1581-1589.
17. Rittschof, D., Lai, C. H., Kok, L. M., and Teo, S. L. M. 2003. Pharmaceuticals as antifoulants: Concept and principles. Biofouling 19(suppl.):207-212.
18. Sebastine, I. M., and Wakeman, R. J. 2003. Consumption and environmental hazards of pharmaceutical substances in the UK. Trans. Chem. 81(B):229-235.
19. Teo, S. L. M., Choong, M. F., and Rittschof, D. 2003. Pharmaceuticals as antifoulants: environmental issues. Proc. Joint NUS-HSA Conference on Environment and Public Health, Singapore, pp. 106-111.
20. Ternes, T. A. 1998. Occurrence of drugs in German sewage treatment plants and rivers. Water Res. 32:3245-3260.
21. Weigel, S., Berger, Urs, Jensen, E., Kallenborn, R., Thoresen, H., and Hufnerfuss, H. 2004. Determination of selected pharmaceuticals and caffeine in sewage and seawater from Tromso/Norway with emphasis on ibuprofen and its metabolites. Chemosphere 56:583-592.