Saxatilin inhibits TNF-α-induced proliferation by suppressing AP-1-dependent IL-8 expression in the ovarian cancer cell line MDAH 2774

Molecular Immunology

Volumn 44, Issue 6, 2007, Pages 1409-1416

  Kim, Dong Seok ^a   Jang, Yoon Jung ^a   Jeon, Ok Hee ^a   Kim, Doo Sik ^a  

^a Yonsei University   (South Korea)

Author keywords

AP 1; Disintegrin; IL 8; Ovarian cancer; TNF

Indexed keywords

ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; SAXATILIN; SNAKE VENOM; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; OVARY CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DISINTEGRINS; FEMALE; GROWTH INHIBITORS; HUMANS; INTERLEUKIN-8; OVARIAN NEOPLASMS; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33748806825     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.05.001     Document Type: Article

References (27)

1. Bobrovnikova-Marjon E.V., Marjon P.L., Barbash O., Vander, Jagt D.L., and Abcouwer S.F. Expression of angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 is highly responsive to ambient glutamine availability: role of nuclear factor-kappaB and activating protein-1. Cancer Res. 64 (2004) 4858-4869
2. Carreiras F., Thiebot B., Leroy-Dudal J., Maubant S., Breton M.F., and Darbeida H. Involvement of alphavbeta 3 integrin and disruption of endothelial fibronectin network during the adhesion of the human ovarian adenocarcinoma cell line IGROV1 on the human umbilical vein cell extracellular matrix. Int. J. Cancer 99 (2002) 800-808
3. Cao Q.Z., Niu G., and Tan H.R. In vitro growth inhibition of human colonic tumor cells by Verapamil. World J. Gastroenterol. 11 15 (2005) 2255-2259
4. Chang Y.J., Liu C.Y., Chiang B.L., Chao Y.C., and Chen C.C. Induction of IL-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: identification of two functional regions. J. Immunol. 173 (2004) 7602-7614
5. Coelho A.L., De Freitas M.S., Mariano-Oliveira A., Rapozo D.C., Pinto L.F., Niewiarowski S., Zingali R.B., Marcinkiewicz C., and Barja-Fidalgo C. RGD- and MLD-disintegrins, jarastatin and EC3, activate integrin-mediated signaling modulating the human neutrophils chemotaxis, apoptosis and IL-8 gene expression. Exp. Cell. Res. 292 2 (2004) 371-384
6. Cruet-Hennequart S., Maubant S., Luis J., Gauduchon P., Staedel C., and Dedhar S. Alpha(v) integrins regulate cell proliferation through integrin-linked kinase (ILK) in ovarian cancer cells. Oncogene 22 (2003) 1688-1702
7. Eferl R., and Wagner E.F. AP-1: a double-edged sword in tumorigenesis. Nat. Rev. Cancer 3 (2003) 859-868
8. Haraoui B. The anti-tumor necrosis factor agents are a major advance in the treatment of rheumatoid arthritis. J. Rheumatol. Suppl. 72 (2005) 46-47
9. Hong S.Y., Koh Y.S., Chung K.H., and Kim D.S. Snake venom disintegrin, saxatilin, inhibits platelet aggregation, human umbilical vein endothelial cell proliferation, and smooth muscle cell migration. Thromb. Res. 105 (2002) 79-86
10. Hong S.Y., Lee H., You W.K., Chung K.H., Kim D.S., and Song K. The snake venom disintegrin salmosin induces apoptosis by disassembly of focal adhesions in bovine capillary endothelial cells. Biochem. Biophys. Res. Commun. 302 (2002) 502-508
11. Hong S.Y., Sohn Y.D., Chung K.H., and Kim D.S. Structural and functional significance of disulfide bonds in saxatilin, a 7.7 kDa disintegrin. Biochem. Biophys. Res. Commun. 293 (2002) 530-536
12. Jacobberger J.W., Sramkoski R.M., Zhang D., Zumstein L.A., Doerksen L.D., Merritt J.A., Wright S.A., and Shults K.E. Bivariate analysis of the p53 pathway to evaluate Ad-p53 gene therapy efficacy. Cytometry 38 5 (1999) 201-213
13. Kang I.C., Lee Y.D., and Kim D.S. A novel disintegrin salmosin inhibits tumor angiogenesis. Cancer Res. 59 (1999) 3754-3760
14. Kim D.S., Han J.H., and Kwon H.J. NF-kappaB and c-Jun-dependent regulation of macrophage inflammatory protein-2 gene expression in response to lipopolysaccharide in RAW 264.7 cells. Mol. Immunol. 40 (2003) 633-643
15. Kim S.I., Kim K.S., Kim H.S., Kim D.S., Jang Y.S., Chung K.H., and Park Y.S. Inhibitory effect of the salmosin gene transferred by cationic liposomes on the progression of B16BL6 tumors. Cancer Res. 63 (2003) 6458-6462
16. Kulbe H., Hagemann T., Szlosarek P.W., Balkwill F.R., and Wilson J.L. The inflammatory cytokine tumor necrosis factor-alpha regulates chemokine receptor expression on ovarian cancer cells. Cancer Res. 65 (2005) 10355-10362
17. Liapis H., Adler L.M., Wick M.R., and Rader J.S. Expression of alpha(v)beta3 integrin is less frequent in ovarian epithelial tumors of low malignant potential in contrast to ovarian carcinomas. Hum. Pathol. 28 (1997) 443-449
18. Liu Z.G. Molecular mechanism of TNF signaling and beyond. Cell Res. 15 (2005) 24-27
19. Lowrie A.G., Salter D.M., and Ross J.A. Latent effects of fibronectin, alpha5beta1 integrin, alphaVbeta5 integrin and the cytoskeleton regulate pancreatic carcinoma cell IL-8 secretion. Br. J. Cancer 91 7 (2004) 1327-1334
20. Malik S.T., Martin D., Hart I., and Balkwill F. Therapy of human ovarian cancer xenografts with intraperitoneal liposome encapsulated muramyl-tripeptide phosphoethanolamine (MTP-PE) and recombinant GM-CSF. Br. J. Cancer 64 (1991) 617-620
21. Martinez-Lemus L.A., Wu X., Wilson E., Hill M.A., Davis G.E., Davis M.J., and Meininger G.A. Integrins as unique receptors for vascular control. J. Vasc. Res. 40 (2003) 211-233
22. Nash M.A., Ferrandina G., Gordinier M., Loercher A., and Freedman R.S. The role of cytokines in both the normal and malignant ovary. Endocr. Relat. Cancer 6 (1999) 93-107
23. Platanas L.C. The p38 mitogen-activated protein kinase pathway and its role in interferon signaling. Pharmacol. Ther. 98 (2003) 129-142
24. Sohn W.J., Lee K.W., Lee Y., Han J.H., Choe Y.K., Kim D.S., and Kwon H.J. Pyrrolidine dithiocarbamate-induced macrophage inflammatory protein-2 gene expression is NF-kappaB-independent but c-Jun-dependent in macrophage cell line RAW 264.7. Mol. Immunol. 42 (2005) 1165-1175
25. Stein B., and Baldwin Jr. A.S. Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B. Mol. Cell. Biol. 13 (1993) 7191-7198
26. Yoneda Y., Kuniyasu H., Crispens M.A., Price J.E., Bucana C.D., and Fidler I.J. Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice. J. Natl. Cancer Inst. 90 (1998) 447-454
27. Zhou Y., Wang S., Gobl A., and Oberg K. Interferon alpha induction of Stat1 and Stat2 and their prognostic significance in carcinoid tumors. Oncology 60 (2001) 330-338