Expression and regulation of Spätzle-processing enzyme in Drosophila

FEBS Letters

Volumn 580, Issue 22, 2006, Pages 5406-5410

  Mulinari, Shai ^a   Häcker, Udo ^a   Castillejo López, Casimiro ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

Drosophila; Fat body; Innate immunity; Lymph gland; RNA interference; Serine protease; Sp tzle processing enzyme; Toll

Indexed keywords

ENZYME; SERINE PROTEINASE; SPATZLE PROCESSING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYME REGULATION; FEMALE; GENE EXPRESSION; INFECTION; INNATE IMMUNITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FAT BODY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; ORGANOGENESIS; SERINE ENDOPEPTIDASES; TOLL-LIKE RECEPTORS;

DROSOPHILA MELANOGASTER;

EID: 33748803063     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.09.009     Document Type: Article

References (20)

1. LeMosy E.K., Hong C.C., and Hashimoto C. Signal transduction by a protease cascade. Trends Cell Biol. 9 (1999) 102-107
2. Anderson K.V., and Nusslein-Volhard C. Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature 311 (1984) 223-227
3. Lemaitre B., Nicolas E., Michaut L., Reichhart J.M., and Hoffmann J.A. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86 (1996) 973-983
4. Khush R.S., Leulier F., and Lemaitre B. Drosophila immunity: two paths to NF-kappaB. Trends Immunol. 22 (2001) 260-264
5. Jang I.H., Chosa N., Kim S.H., Nam H.J., Lemaitre B., Ochiai M., Kambris Z., Brun S., Hashimoto C., Ashida M., Brey P.T., and Lee W.J. A spatzle-processing enzyme required for toll signaling activation in Drosophila innate immunity. Dev. Cell 10 (2006) 45-55
6. Irving P., Troxler L., Heuer T.S., Belvin M., Kopczynski C., Reichhart J.M., Hoffmann J.A., and Hetru C. A genome-wide analysis of immune responses in Drosophila. Proc. Natl. Acad. Sci. USA 98 (2001) 15119-15124
7. Boutros M., Agaisse H., and Perrimon N. Sequential activation of signaling pathways during innate immune responses in Drosophila. Dev. Cell 3 (2002) 711-722
8. De Gregorio E., Spellman P.T., Rubin G.M., and Lemaitre B. Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays. Proc. Natl. Acad. Sci. USA 98 (2001) 12590-12595
9. Kalidas S., and Smith D.P. Novel genomic cDNA hybrids produce effective RNA interference in adult Drosophila. Neuron 33 (2002) 177-184
10. Castillejo-Lopez C., Arias W.M., and Baumgartner S. The fat-like gene of Drosophila is the true orthologue of vertebrate fat cadherins and is involved in the formation of tubular organs. J. Biol. Chem. 279 (2004) 24034-24043
11. Tautz D., and Pfeifle C. A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98 (1989) 81-85
12. Kambris Z., Brun S., Jang I.H., Nam H.J., Romeo Y., Takahashi K., Lee W.J., Ueda R., and Lemaitre B. Drosophila immunity: a large-scale in vivo RNAi screen identifies five serine proteases required for toll activation. Curr. Biol. 16 (2006) 808-813
13. Riechmann V., Rehorn K.P., Reuter R., and Leptin M. The genetic control of the distinction between fat body and gonadal mesoderm in Drosophila. Development 125 (1998) 713-723
14. Sam S., Leise W., and Hoshizaki D.K. The serpent gene is necessary for progression through the early stages of fat-body development. Mech. Dev. 60 (1996) 197-205
15. Miller J.M., Oligino T., Pazdera M., Lopez A.J., and Hoshizaki D.K. Identification of fat-cell enhancer regions in Drosophila melanogaster. Insect Mol. Biol. 11 (2002) 67-77
16. Holz A., Bossinger B., Strasser T., Janning W., and Klapper R. The two origins of hemocytes in Drosophila. Development 130 (2003) 4955-4962
17. Lanot R., Zachary D., Holder F., and Meister M. Postembryonic hematopoiesis in Drosophila. Dev. Biol. 230 (2001) 243-257
18. Weber A.N., Tauszig-Delamasure S., Hoffmann J.A., Lelievre E., Gascan H., Ray K.P., Morse M.A., Imler J.L., and Gay N.J. Binding of the Drosophila cytokine Spatzle to Toll is direct and establishes signaling. Nat. Immunol. 4 (2003) 794-800
19. De Gregorio E., Spellman P.T., Tzou P., Rubin G.M., and Lemaitre B. The Toll and Imd pathways are the major regulators of the immune response in Drosophila. EMBO J. 21 (2002) 2568-2579
20. Campos-Ortega, J., and Hartenstein, V. (1985). The embryonic development of Drosophila melanogaster (Berlin).