메뉴 건너뛰기




Volumn 44, Issue 5, 2007, Pages 916-925

A human monoclonal IgG1 potently neutralizing the pro-inflammatory cytokine GM-CSF

Author keywords

Cytokine; Eosinophil; GM CSF; Inflammation; Monoclonal antibody; Treatment

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN G1 ANTIBODY; INTERLEUKIN 1BETA; MONOCLONAL ANTIBODY MT 203; MT 203; UNCLASSIFIED DRUG;

EID: 33748800252     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.03.020     Document Type: Article
Times cited : (30)

References (30)
  • 2
    • 0037044792 scopus 로고    scopus 로고
    • Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo
    • Bozinovski S., Jones J.E., Vlahos R., Hamilton J.A., and Anderson G.P. Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo. J. Biol. Chem. 277 (2002) 42808-42814
    • (2002) J. Biol. Chem. , vol.277 , pp. 42808-42814
    • Bozinovski, S.1    Jones, J.E.2    Vlahos, R.3    Hamilton, J.A.4    Anderson, G.P.5
  • 3
    • 0032193230 scopus 로고    scopus 로고
    • Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice
    • Campbell I.K., Rich M.J., Bischof R.J., Dunn A.R., Grail D., and Hamilton J.A. Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice. J. Immunol. 161 (1998) 3639-3644
    • (1998) J. Immunol. , vol.161 , pp. 3639-3644
    • Campbell, I.K.1    Rich, M.J.2    Bischof, R.J.3    Dunn, A.R.4    Grail, D.5    Hamilton, J.A.6
  • 6
    • 0025264198 scopus 로고
    • Granulocyte-macrophage colony stimulating factor from human lymphocytes. The effect of glycosylation on receptor binding and biological activity
    • Cebon J., Nicola N., Ward M., Gardner I., Dempsey P., Layton J., Duhrsen U., Burgess A.W., Nice E., and Morstyn G. Granulocyte-macrophage colony stimulating factor from human lymphocytes. The effect of glycosylation on receptor binding and biological activity. J. Biol. Chem. 265 (1990) 4483-4491
    • (1990) J. Biol. Chem. , vol.265 , pp. 4483-4491
    • Cebon, J.1    Nicola, N.2    Ward, M.3    Gardner, I.4    Dempsey, P.5    Layton, J.6    Duhrsen, U.7    Burgess, A.W.8    Nice, E.9    Morstyn, G.10
  • 7
    • 0034851864 scopus 로고    scopus 로고
    • Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease
    • Cook A.D., Braine E.L., Campbell I.K., Rich M.J., and Hamilton J.A. Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease. Arthritis Res. 3 (2001) 293-298
    • (2001) Arthritis Res. , vol.3 , pp. 293-298
    • Cook, A.D.1    Braine, E.L.2    Campbell, I.K.3    Rich, M.J.4    Hamilton, J.A.5
  • 9
    • 0026320870 scopus 로고
    • Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor
    • Diederichs K., Boone T., and Karplus P.A. Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor. Science 254 (1991) 1779-1782
    • (1991) Science , vol.254 , pp. 1779-1782
    • Diederichs, K.1    Boone, T.2    Karplus, P.A.3
  • 11
    • 0026694415 scopus 로고
    • Plasma GM-CSF concentrations in rheumatoid arthritis, systemic lupus erythematosus and spondyloarthropathy
    • Fiehn C., Wermann M., Pezzutto A., Hufner M., and Heilig B. Plasma GM-CSF concentrations in rheumatoid arthritis, systemic lupus erythematosus and spondyloarthropathy. Z. Rheumatol. 51 (1992) 121-126
    • (1992) Z. Rheumatol. , vol.51 , pp. 121-126
    • Fiehn, C.1    Wermann, M.2    Pezzutto, A.3    Hufner, M.4    Heilig, B.5
  • 12
    • 0642335540 scopus 로고    scopus 로고
    • GM-CSF and dendritic cells in allergic airway inflammation: basic mechanisms and prospects for therapeutic intervention
    • Gajewska B.U., Wiley R.E., and Jordana M. GM-CSF and dendritic cells in allergic airway inflammation: basic mechanisms and prospects for therapeutic intervention. Curr. Drug Targets Inflamm. Allergy 2 (2003) 279-292
    • (2003) Curr. Drug Targets Inflamm. Allergy , vol.2 , pp. 279-292
    • Gajewska, B.U.1    Wiley, R.E.2    Jordana, M.3
  • 13
    • 0036679853 scopus 로고    scopus 로고
    • GM-CSF in inflammation and autoimmunity
    • Hamilton J.A. GM-CSF in inflammation and autoimmunity. Trends Immunol. 23 (2002) 403-408
    • (2002) Trends Immunol. , vol.23 , pp. 403-408
    • Hamilton, J.A.1
  • 14
    • 0028233122 scopus 로고
    • Identification of residues in the first and fourth helices of human granulocyte-macrophage colony-stimulating factor involved in biologic activity and in binding to the alpha- and beta-chains of its receptor
    • Hercus T.R., Cambareri B., Dottore M., Woodcock J., Bagley C.J., Vadas M.A., Shannon M.F., and Lopez A.F. Identification of residues in the first and fourth helices of human granulocyte-macrophage colony-stimulating factor involved in biologic activity and in binding to the alpha- and beta-chains of its receptor. Blood 83 (1994) 3500-3508
    • (1994) Blood , vol.83 , pp. 3500-3508
    • Hercus, T.R.1    Cambareri, B.2    Dottore, M.3    Woodcock, J.4    Bagley, C.J.5    Vadas, M.A.6    Shannon, M.F.7    Lopez, A.F.8
  • 18
    • 3442896883 scopus 로고    scopus 로고
    • Cytokine-regulated accumulation of eosinophils in inflammatory disease
    • Lampinen M., Carlson M., Hakansson L.D., and Venge P. Cytokine-regulated accumulation of eosinophils in inflammatory disease. Allergy 59 (2004) 793-805
    • (2004) Allergy , vol.59 , pp. 793-805
    • Lampinen, M.1    Carlson, M.2    Hakansson, L.D.3    Venge, P.4
  • 19
    • 0030933066 scopus 로고    scopus 로고
    • Stimulation of blood mononuclear cells of atopic children with the relevant allergen induces the release of eosinophil chemotaxins such as IL-3, IL-5, and GM-CSF
    • Lantero S., Sacco O., Scala C., and Rossi G.A. Stimulation of blood mononuclear cells of atopic children with the relevant allergen induces the release of eosinophil chemotaxins such as IL-3, IL-5, and GM-CSF. J. Asthma 34 (1997) 141-152
    • (1997) J. Asthma , vol.34 , pp. 141-152
    • Lantero, S.1    Sacco, O.2    Scala, C.3    Rossi, G.A.4
  • 22
    • 0035020015 scopus 로고    scopus 로고
    • Anti-self antibodies selected from a human IgD heavy chain repertoire: a novel approach to generate therapeutic human antibodies against tumor-associated differentiation antigens
    • Raum T., Gruber R., Riethmuller G., and Kufer P. Anti-self antibodies selected from a human IgD heavy chain repertoire: a novel approach to generate therapeutic human antibodies against tumor-associated differentiation antigens. Cancer Immunol. Immunother. 50 (2001) 141-150
    • (2001) Cancer Immunol. Immunother. , vol.50 , pp. 141-150
    • Raum, T.1    Gruber, R.2    Riethmuller, G.3    Kufer, P.4
  • 23
    • 0035424679 scopus 로고    scopus 로고
    • Dendritic cells (DCs) in rheumatoid arthritis (RA): progenitor cells and soluble factors contained in RA synovial fluid yield a subset of myeloid DCs that preferentially activate Th1 inflammatory-type responses
    • Santiago-Schwarz F., Anand P., Liu S., and Carsons S.E. Dendritic cells (DCs) in rheumatoid arthritis (RA): progenitor cells and soluble factors contained in RA synovial fluid yield a subset of myeloid DCs that preferentially activate Th1 inflammatory-type responses. J. Immunol. 167 (2001) 1758-1768
    • (2001) J. Immunol. , vol.167 , pp. 1758-1768
    • Santiago-Schwarz, F.1    Anand, P.2    Liu, S.3    Carsons, S.E.4
  • 24
    • 0034070974 scopus 로고    scopus 로고
    • Critical role of neutrophils for the generation of psoriasiform skin lesions in flaky skin mice
    • Schon M., Denzer D., Kubitza R.C., Ruzicka T., and Schon M.P. Critical role of neutrophils for the generation of psoriasiform skin lesions in flaky skin mice. J. Invest. Dermatol. 114 (2000) 976-983
    • (2000) J. Invest. Dermatol. , vol.114 , pp. 976-983
    • Schon, M.1    Denzer, D.2    Kubitza, R.C.3    Ruzicka, T.4    Schon, M.P.5
  • 25
    • 10944261085 scopus 로고    scopus 로고
    • Do anti-TNF agents have equal efficacy in patients with rheumatoid arthritis?
    • Schwartzman S., Fleischmann R., and Morgan Jr. G.J. Do anti-TNF agents have equal efficacy in patients with rheumatoid arthritis?. Arthritis Res. Ther. 6 Suppl. 2 (2004) S3-S11
    • (2004) Arthritis Res. Ther. , vol.6 , Issue.SUPPL. 2
    • Schwartzman, S.1    Fleischmann, R.2    Morgan Jr., G.J.3
  • 26
    • 0015577703 scopus 로고
    • A low molecular weight factor in lung-conditioned medium stimulating granulocyte and monocyte colony formation in vitro
    • Sheridan J.W., and Metcalf D. A low molecular weight factor in lung-conditioned medium stimulating granulocyte and monocyte colony formation in vitro. J. Cell. Physiol. 81 (1973) 11-23
    • (1973) J. Cell. Physiol. , vol.81 , pp. 11-23
    • Sheridan, J.W.1    Metcalf, D.2
  • 27
    • 0027176276 scopus 로고
    • Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids
    • Sousa A.R., Poston R.N., Lane S.J., Nakhosteen J.A., and Lee T.H. Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids. Am. Rev. Respir. Dis. 147 (1993) 1557-1561
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. 1557-1561
    • Sousa, A.R.1    Poston, R.N.2    Lane, S.J.3    Nakhosteen, J.A.4    Lee, T.H.5
  • 28
    • 0028144783 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma
    • Woolley K.L., Adelroth E., Woolley M.J., Ellis R., Jordana M., and O'Byrne P.M. Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma. Eur. Respir. J. 7 (1994) 1576-1584
    • (1994) Eur. Respir. J. , vol.7 , pp. 1576-1584
    • Woolley, K.L.1    Adelroth, E.2    Woolley, M.J.3    Ellis, R.4    Jordana, M.5    O'Byrne, P.M.6
  • 29
  • 30
    • 0036826485 scopus 로고    scopus 로고
    • Attenuation of airway hyperresponsiveness in a murine asthma model by neutralization of granulocyte-macrophage colony-stimulating factor (GM-CSF)
    • Yamashita N., Tashimo H., Ishida H., Kaneko F., Nakano J., Kato H., Hirai K., Horiuchi T., and Ohta K. Attenuation of airway hyperresponsiveness in a murine asthma model by neutralization of granulocyte-macrophage colony-stimulating factor (GM-CSF). Cell. Immunol. 219 (2002) 92-97
    • (2002) Cell. Immunol. , vol.219 , pp. 92-97
    • Yamashita, N.1    Tashimo, H.2    Ishida, H.3    Kaneko, F.4    Nakano, J.5    Kato, H.6    Hirai, K.7    Horiuchi, T.8    Ohta, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.