-
1
-
-
1642405415
-
Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4
-
Bozinovski S., Jones J., Beavitt S.J., Cook A.D., Hamilton J.A., and Anderson G.P. Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4. Am. J. Physiol. Lung Cell. Mol. Physiol. 286 (2004) L877-L885
-
(2004)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.286
-
-
Bozinovski, S.1
Jones, J.2
Beavitt, S.J.3
Cook, A.D.4
Hamilton, J.A.5
Anderson, G.P.6
-
2
-
-
0037044792
-
Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo
-
Bozinovski S., Jones J.E., Vlahos R., Hamilton J.A., and Anderson G.P. Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NFkappa B and AP-1 in vivo. J. Biol. Chem. 277 (2002) 42808-42814
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42808-42814
-
-
Bozinovski, S.1
Jones, J.E.2
Vlahos, R.3
Hamilton, J.A.4
Anderson, G.P.5
-
3
-
-
0032193230
-
Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice
-
Campbell I.K., Rich M.J., Bischof R.J., Dunn A.R., Grail D., and Hamilton J.A. Protection from collagen-induced arthritis in granulocyte-macrophage colony-stimulating factor-deficient mice. J. Immunol. 161 (1998) 3639-3644
-
(1998)
J. Immunol.
, vol.161
, pp. 3639-3644
-
-
Campbell, I.K.1
Rich, M.J.2
Bischof, R.J.3
Dunn, A.R.4
Grail, D.5
Hamilton, J.A.6
-
4
-
-
8444223053
-
Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism
-
Cates E.C., Fattouh R., Wattie J., Inman M.D., Goncharova S., Coyle A.J., Gutierrez-Ramos J.C., and Jordana M. Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism. J. Immunol. 173 (2004) 6384-6392
-
(2004)
J. Immunol.
, vol.173
, pp. 6384-6392
-
-
Cates, E.C.1
Fattouh, R.2
Wattie, J.3
Inman, M.D.4
Goncharova, S.5
Coyle, A.J.6
Gutierrez-Ramos, J.C.7
Jordana, M.8
-
5
-
-
0038743016
-
Effect of GM-CSF on immune, inflammatory, and clinical responses to ragweed in a novel mouse model of mucosal sensitization
-
Cates E.C., Gajewska B.U., Goncharova S., Alvarez D., Fattouh R., Coyle A.J., Gutierrez-Ramos J.C., and Jordana M. Effect of GM-CSF on immune, inflammatory, and clinical responses to ragweed in a novel mouse model of mucosal sensitization. J. Allergy Clin. Immunol. 111 (2003) 1076-1086
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 1076-1086
-
-
Cates, E.C.1
Gajewska, B.U.2
Goncharova, S.3
Alvarez, D.4
Fattouh, R.5
Coyle, A.J.6
Gutierrez-Ramos, J.C.7
Jordana, M.8
-
6
-
-
0025264198
-
Granulocyte-macrophage colony stimulating factor from human lymphocytes. The effect of glycosylation on receptor binding and biological activity
-
Cebon J., Nicola N., Ward M., Gardner I., Dempsey P., Layton J., Duhrsen U., Burgess A.W., Nice E., and Morstyn G. Granulocyte-macrophage colony stimulating factor from human lymphocytes. The effect of glycosylation on receptor binding and biological activity. J. Biol. Chem. 265 (1990) 4483-4491
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 4483-4491
-
-
Cebon, J.1
Nicola, N.2
Ward, M.3
Gardner, I.4
Dempsey, P.5
Layton, J.6
Duhrsen, U.7
Burgess, A.W.8
Nice, E.9
Morstyn, G.10
-
7
-
-
0034851864
-
Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease
-
Cook A.D., Braine E.L., Campbell I.K., Rich M.J., and Hamilton J.A. Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease. Arthritis Res. 3 (2001) 293-298
-
(2001)
Arthritis Res.
, vol.3
, pp. 293-298
-
-
Cook, A.D.1
Braine, E.L.2
Campbell, I.K.3
Rich, M.J.4
Hamilton, J.A.5
-
8
-
-
0025886355
-
Flare-up of rheumatoid arthritis during GM-CSF treatment after chemotherapy
-
de Vries E.G., Willemse P.H., Biesma B., Stern A.C., Limburg P.C., and Vellenga E. Flare-up of rheumatoid arthritis during GM-CSF treatment after chemotherapy. Lancet 338 (1991) 517-518
-
(1991)
Lancet
, vol.338
, pp. 517-518
-
-
de Vries, E.G.1
Willemse, P.H.2
Biesma, B.3
Stern, A.C.4
Limburg, P.C.5
Vellenga, E.6
-
9
-
-
0026320870
-
Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor
-
Diederichs K., Boone T., and Karplus P.A. Novel fold and putative receptor binding site of granulocyte-macrophage colony-stimulating factor. Science 254 (1991) 1779-1782
-
(1991)
Science
, vol.254
, pp. 1779-1782
-
-
Diederichs, K.1
Boone, T.2
Karplus, P.A.3
-
11
-
-
0026694415
-
Plasma GM-CSF concentrations in rheumatoid arthritis, systemic lupus erythematosus and spondyloarthropathy
-
Fiehn C., Wermann M., Pezzutto A., Hufner M., and Heilig B. Plasma GM-CSF concentrations in rheumatoid arthritis, systemic lupus erythematosus and spondyloarthropathy. Z. Rheumatol. 51 (1992) 121-126
-
(1992)
Z. Rheumatol.
, vol.51
, pp. 121-126
-
-
Fiehn, C.1
Wermann, M.2
Pezzutto, A.3
Hufner, M.4
Heilig, B.5
-
12
-
-
0642335540
-
GM-CSF and dendritic cells in allergic airway inflammation: basic mechanisms and prospects for therapeutic intervention
-
Gajewska B.U., Wiley R.E., and Jordana M. GM-CSF and dendritic cells in allergic airway inflammation: basic mechanisms and prospects for therapeutic intervention. Curr. Drug Targets Inflamm. Allergy 2 (2003) 279-292
-
(2003)
Curr. Drug Targets Inflamm. Allergy
, vol.2
, pp. 279-292
-
-
Gajewska, B.U.1
Wiley, R.E.2
Jordana, M.3
-
13
-
-
0036679853
-
GM-CSF in inflammation and autoimmunity
-
Hamilton J.A. GM-CSF in inflammation and autoimmunity. Trends Immunol. 23 (2002) 403-408
-
(2002)
Trends Immunol.
, vol.23
, pp. 403-408
-
-
Hamilton, J.A.1
-
14
-
-
0028233122
-
Identification of residues in the first and fourth helices of human granulocyte-macrophage colony-stimulating factor involved in biologic activity and in binding to the alpha- and beta-chains of its receptor
-
Hercus T.R., Cambareri B., Dottore M., Woodcock J., Bagley C.J., Vadas M.A., Shannon M.F., and Lopez A.F. Identification of residues in the first and fourth helices of human granulocyte-macrophage colony-stimulating factor involved in biologic activity and in binding to the alpha- and beta-chains of its receptor. Blood 83 (1994) 3500-3508
-
(1994)
Blood
, vol.83
, pp. 3500-3508
-
-
Hercus, T.R.1
Cambareri, B.2
Dottore, M.3
Woodcock, J.4
Bagley, C.J.5
Vadas, M.A.6
Shannon, M.F.7
Lopez, A.F.8
-
15
-
-
4544274172
-
A critical role for eosinophils in allergic airways remodeling
-
Humbles A.A., Lloyd C.M., McMillan S.J., Friend D.S., Xanthou G., McKenna E.E., Ghiran S., Gerard N.P., Yu C., Orkin S.H., and Gerard C. A critical role for eosinophils in allergic airways remodeling. Science 305 (2004) 1776-1779
-
(2004)
Science
, vol.305
, pp. 1776-1779
-
-
Humbles, A.A.1
Lloyd, C.M.2
McMillan, S.J.3
Friend, D.S.4
Xanthou, G.5
McKenna, E.E.6
Ghiran, S.7
Gerard, N.P.8
Yu, C.9
Orkin, S.H.10
Gerard, C.11
-
16
-
-
0033941414
-
Delayed eosinophil apoptosis in asthma
-
Kankaanranta H., Lindsay M.A., Giembycz M.A., Zhang X., Moilanen E., and Barnes P.J. Delayed eosinophil apoptosis in asthma. J. Allergy Clin. Immunol. 106 (2000) 77-83
-
(2000)
J. Allergy Clin. Immunol.
, vol.106
, pp. 77-83
-
-
Kankaanranta, H.1
Lindsay, M.A.2
Giembycz, M.A.3
Zhang, X.4
Moilanen, E.5
Barnes, P.J.6
-
17
-
-
0030983513
-
Upregulation of alpha GM-CSF-receptor in nonatopic asthma but not in atopic asthma
-
Kotsimbos A.T., Humbert M., Minshall E., Durham S., Pfister R., Menz G., Tavernier J., Kay A.B., and Hamid Q. Upregulation of alpha GM-CSF-receptor in nonatopic asthma but not in atopic asthma. J. Allergy Clin. Immunol. 99 (1997) 666-672
-
(1997)
J. Allergy Clin. Immunol.
, vol.99
, pp. 666-672
-
-
Kotsimbos, A.T.1
Humbert, M.2
Minshall, E.3
Durham, S.4
Pfister, R.5
Menz, G.6
Tavernier, J.7
Kay, A.B.8
Hamid, Q.9
-
18
-
-
3442896883
-
Cytokine-regulated accumulation of eosinophils in inflammatory disease
-
Lampinen M., Carlson M., Hakansson L.D., and Venge P. Cytokine-regulated accumulation of eosinophils in inflammatory disease. Allergy 59 (2004) 793-805
-
(2004)
Allergy
, vol.59
, pp. 793-805
-
-
Lampinen, M.1
Carlson, M.2
Hakansson, L.D.3
Venge, P.4
-
19
-
-
0030933066
-
Stimulation of blood mononuclear cells of atopic children with the relevant allergen induces the release of eosinophil chemotaxins such as IL-3, IL-5, and GM-CSF
-
Lantero S., Sacco O., Scala C., and Rossi G.A. Stimulation of blood mononuclear cells of atopic children with the relevant allergen induces the release of eosinophil chemotaxins such as IL-3, IL-5, and GM-CSF. J. Asthma 34 (1997) 141-152
-
(1997)
J. Asthma
, vol.34
, pp. 141-152
-
-
Lantero, S.1
Sacco, O.2
Scala, C.3
Rossi, G.A.4
-
20
-
-
0035476518
-
Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis
-
McQualter J.L., Darwiche R., Ewing C., Onuki M., Kay T.W., Hamilton J.A., Reid H.H., and Bernard C.C. Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis. J. Exp. Med. 194 (2001) 873-882
-
(2001)
J. Exp. Med.
, vol.194
, pp. 873-882
-
-
McQualter, J.L.1
Darwiche, R.2
Ewing, C.3
Onuki, M.4
Kay, T.W.5
Hamilton, J.A.6
Reid, H.H.7
Bernard, C.C.8
-
21
-
-
0034643935
-
Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor
-
Openshaw H., Stuve O., Antel J.P., Nash R., Lund B.T., Weiner L.P., Kashyap A., McSweeney P., and Forman S. Multiple sclerosis flares associated with recombinant granulocyte colony-stimulating factor. Neurology 54 (2000) 2147-2150
-
(2000)
Neurology
, vol.54
, pp. 2147-2150
-
-
Openshaw, H.1
Stuve, O.2
Antel, J.P.3
Nash, R.4
Lund, B.T.5
Weiner, L.P.6
Kashyap, A.7
McSweeney, P.8
Forman, S.9
-
22
-
-
0035020015
-
Anti-self antibodies selected from a human IgD heavy chain repertoire: a novel approach to generate therapeutic human antibodies against tumor-associated differentiation antigens
-
Raum T., Gruber R., Riethmuller G., and Kufer P. Anti-self antibodies selected from a human IgD heavy chain repertoire: a novel approach to generate therapeutic human antibodies against tumor-associated differentiation antigens. Cancer Immunol. Immunother. 50 (2001) 141-150
-
(2001)
Cancer Immunol. Immunother.
, vol.50
, pp. 141-150
-
-
Raum, T.1
Gruber, R.2
Riethmuller, G.3
Kufer, P.4
-
23
-
-
0035424679
-
Dendritic cells (DCs) in rheumatoid arthritis (RA): progenitor cells and soluble factors contained in RA synovial fluid yield a subset of myeloid DCs that preferentially activate Th1 inflammatory-type responses
-
Santiago-Schwarz F., Anand P., Liu S., and Carsons S.E. Dendritic cells (DCs) in rheumatoid arthritis (RA): progenitor cells and soluble factors contained in RA synovial fluid yield a subset of myeloid DCs that preferentially activate Th1 inflammatory-type responses. J. Immunol. 167 (2001) 1758-1768
-
(2001)
J. Immunol.
, vol.167
, pp. 1758-1768
-
-
Santiago-Schwarz, F.1
Anand, P.2
Liu, S.3
Carsons, S.E.4
-
24
-
-
0034070974
-
Critical role of neutrophils for the generation of psoriasiform skin lesions in flaky skin mice
-
Schon M., Denzer D., Kubitza R.C., Ruzicka T., and Schon M.P. Critical role of neutrophils for the generation of psoriasiform skin lesions in flaky skin mice. J. Invest. Dermatol. 114 (2000) 976-983
-
(2000)
J. Invest. Dermatol.
, vol.114
, pp. 976-983
-
-
Schon, M.1
Denzer, D.2
Kubitza, R.C.3
Ruzicka, T.4
Schon, M.P.5
-
25
-
-
10944261085
-
Do anti-TNF agents have equal efficacy in patients with rheumatoid arthritis?
-
Schwartzman S., Fleischmann R., and Morgan Jr. G.J. Do anti-TNF agents have equal efficacy in patients with rheumatoid arthritis?. Arthritis Res. Ther. 6 Suppl. 2 (2004) S3-S11
-
(2004)
Arthritis Res. Ther.
, vol.6
, Issue.SUPPL. 2
-
-
Schwartzman, S.1
Fleischmann, R.2
Morgan Jr., G.J.3
-
26
-
-
0015577703
-
A low molecular weight factor in lung-conditioned medium stimulating granulocyte and monocyte colony formation in vitro
-
Sheridan J.W., and Metcalf D. A low molecular weight factor in lung-conditioned medium stimulating granulocyte and monocyte colony formation in vitro. J. Cell. Physiol. 81 (1973) 11-23
-
(1973)
J. Cell. Physiol.
, vol.81
, pp. 11-23
-
-
Sheridan, J.W.1
Metcalf, D.2
-
27
-
-
0027176276
-
Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids
-
Sousa A.R., Poston R.N., Lane S.J., Nakhosteen J.A., and Lee T.H. Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids. Am. Rev. Respir. Dis. 147 (1993) 1557-1561
-
(1993)
Am. Rev. Respir. Dis.
, vol.147
, pp. 1557-1561
-
-
Sousa, A.R.1
Poston, R.N.2
Lane, S.J.3
Nakhosteen, J.A.4
Lee, T.H.5
-
28
-
-
0028144783
-
Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma
-
Woolley K.L., Adelroth E., Woolley M.J., Ellis R., Jordana M., and O'Byrne P.M. Granulocyte-macrophage colony-stimulating factor, eosinophils and eosinophil cationic protein in subjects with and without mild, stable, atopic asthma. Eur. Respir. J. 7 (1994) 1576-1584
-
(1994)
Eur. Respir. J.
, vol.7
, pp. 1576-1584
-
-
Woolley, K.L.1
Adelroth, E.2
Woolley, M.J.3
Ellis, R.4
Jordana, M.5
O'Byrne, P.M.6
-
29
-
-
0038783439
-
GM-CSF restores innate, but not adaptive, immune responses in glucocorticoid-immunosuppressed human blood in vitro
-
Xu J., Lucas R., Schuchmann M., Kuhnle S., Meergans T., Barreiros A.P., Lohse A.W., Otto G., and Wendel A. GM-CSF restores innate, but not adaptive, immune responses in glucocorticoid-immunosuppressed human blood in vitro. J. Immunol. 171 (2003) 938-947
-
(2003)
J. Immunol.
, vol.171
, pp. 938-947
-
-
Xu, J.1
Lucas, R.2
Schuchmann, M.3
Kuhnle, S.4
Meergans, T.5
Barreiros, A.P.6
Lohse, A.W.7
Otto, G.8
Wendel, A.9
-
30
-
-
0036826485
-
Attenuation of airway hyperresponsiveness in a murine asthma model by neutralization of granulocyte-macrophage colony-stimulating factor (GM-CSF)
-
Yamashita N., Tashimo H., Ishida H., Kaneko F., Nakano J., Kato H., Hirai K., Horiuchi T., and Ohta K. Attenuation of airway hyperresponsiveness in a murine asthma model by neutralization of granulocyte-macrophage colony-stimulating factor (GM-CSF). Cell. Immunol. 219 (2002) 92-97
-
(2002)
Cell. Immunol.
, vol.219
, pp. 92-97
-
-
Yamashita, N.1
Tashimo, H.2
Ishida, H.3
Kaneko, F.4
Nakano, J.5
Kato, H.6
Hirai, K.7
Horiuchi, T.8
Ohta, K.9
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