Positive family history of coronary artery disease is associated with reduced myocardial vasoreactivity in healthy men

International Journal of Cardiology

Volumn 112, Issue 3, 2006, Pages 289-294

  Sundell, Jan ^a,b   Laine, Hanna ^a,b   Raitakari, Olli T ^a,b   Luotolahti, Matti ^b   Nuutila, Pirjo ^a,b   Knuuti, Juhani ^a  

^a TURKU PET CENTRE   (Finland)

^b TURKU UNIVERSITY   (Finland)

Author keywords

Adenosine; Family history of coronary artery disease; Insulin; Myocardial blood flow; Positron emission tomography

Indexed keywords

ADENOSINE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; AGE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD VESSEL REACTIVITY; BODY MASS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FAMILY HISTORY; HEART MUSCLE; HEART MUSCLE BLOOD FLOW; HUMAN; HYPERINSULINEMIA; INSULIN INFUSION; MALE; NORMAL HUMAN; PHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ADULT; BLOOD GLUCOSE; BLOOD PRESSURE; CORONARY CIRCULATION; CORONARY DISEASE; FATTY ACIDS, NONESTERIFIED; HEART RATE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INSULIN; MALE; POSITRON-EMISSION TOMOGRAPHY; REGIONAL BLOOD FLOW; RISK FACTORS;

EID: 33748785165     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijcard.2005.09.016     Document Type: Article

References (30)

1. Shea S., Ottman R., Gabrieli C., Stein Z., and Nichols A. Family history as an independent risk factor for coronary artery disease. J Am Coll Cardiol 4 (1984) 793-801
2. De Bacquer D., De Backer G., Kornitzer M., and Blackburn H. Parental history of premature coronary heart disease mortality and signs of ischemia on the resting electrocardiogram. J Am Coll Cardiol 33 (1999) 1491-1498
3. Schachinger V., Britten M.B., Elsner M., Walter D.H., Scharrer I., and Zeiher A.M. A positive family history of premature coronary artery disease is associated with impaired endothelium-dependent coronary blood flow regulation. Circulation 100 (1999) 1502-1508
4. Sdringola S., Patel D., and Gould K.L. High prevalence of myocardial perfusion abnormalities on positron emission tomography in asymptomatic persons with a parent or sibling with coronary artery disease. Circulation 103 (2001) 496-501
5. Pirich C., Leber A., Knez A., et al. Relation of coronary vasoreactivity and coronary calcification in asymptomatic subjects with a family history of premature coronary artery disease. Eur J Nucl Med Mol Imaging 31 (2004) 663-670
6. Dayanikli F., Grambow D., Muzik O., Mosca L., Rubenfire M., and Schwaiger M. Early detection of abnormal coronary flow reserve in asymptomatic men at high risk for coronary artery disease using positron emission tomography. Circulation 90 (1994) 808-817
7. Vita J.A., Treasure C.B., Nabel E.G., et al. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation 81 (1990) 491-497
8. Schachinger V., Britten M.B., and Zeiher A.M. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 101 (2000) 1899-1906
9. Pitkanen O.P., Raitakari O.T., Ronnemaa T., et al. Influence of cardiovascular risk status on coronary flow reserve in healthy young men. Am J Cardiol 79 (1997) 1690-1692
10. Buus N.H., Bottcher M., Hermansen F., Sander M., Nielsen T.T., and Mulvany M.J. Influence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemia. Circulation 104 (2001) 2305-2310
11. Scherrer U. Insulin and the regulation of cardiovascular system: role of the l-arginine nitric oxide pathway and the sympathetic nervous system. In: Lüscher T.E. (Ed). The endotheliuma in cardiovascular disease (1995), Springer Verlag, Heidelberg 108-128
12. Sobrevia L., Nadal A., Yudilevich D.L., and Mann G.E. Activation of l-arginine transport (system y+) and nitric oxide synthase by elevated glucose and insulin in human endothelial cells. J Physiol 490 Pt 3 (1996) 775-781
13. Steinberg H.O., Chaker H., Leaming R., Johnson A., Brechtel G., and Baron A.D. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 97 (1996) 2601-2610
14. Taddei S., Virdis A., Mattei P., Natali A., Ferrannini E., and Salvetti A. Effect of insulin on acetylcholine-induced vasodilation in normotensive subjects and patients with essential hypertension. Circulation 92 (1995) 2911-2918
15. DeFronzo R.A., Tobin J.D., and Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237 (1979) E214-E223
16. Crouzel C., Clark J., and Brihaye C. Radiochemistry automation for PET. In: Stöckling G., and Pike V. (Eds). Radiopharmaceuticals for positron emission tomography (1993), Kluwer Academic Publishers, Dordrecht, Netherlands 45-90
17. Laine H., Raitakari O.T., Niinikoski H., et al. Early impairment of coronary flow reserve in young men with borderline hypertension. J Am Coll Cardiol 32 (1998) 147-153
18. Iida H., Takahashi A., Tamura Y., Ono Y., and Lammertsma A.A. Myocardial blood flow: comparison of oxygen-15-water bolus injection, slow infusion and oxygen-15-carbon dioxide slow inhalation. J Nucl Med 36 (1995) 78-85
19. Iida H., Rhodes C.G., de Silva R., et al. Use of the left ventricular time-activity curve as a noninvasive input function in dynamic oxygen-15-water positron emission tomography. J Nucl Med 33 (1992) 1669-1677
20. Kadish A., Little R., and Sternberg J. A new and rapid method for the determination of glucose by measurement of rate of oxygen consumption. Clin Chem 14 (1968) 116-131
21. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
22. Gaeta G., De Michele M., Cuomo S., et al. Arterial abnormalities in the offspring of patients with premature myocardial infarction. N Engl J Med 343 (2000) 840-846
23. Mayhan W.G. Endothelium-dependent responses of cerebral arterioles to adenosine 5′-diphosphate. J Vasc Res 29 (1992) 353-358
24. Wilson R.F., Wyche K., Christensen B.V., Zimmer S., and Laxson D.D. Effects of adenosine on human coronary arterial circulation. Circulation 82 (1990) 1595-1606
25. Opie L.H. The Heart (1998), Lippincott-Raven Publishers, Philadelphia, New York
26. Ferrannini E., Santoro D., Bonadonna R., Parodi A., and Camici O. Metabolic and hemodynamic effects of insulin on human hearts. Am J Physiol 264 (1993) E308-E315
27. Laine H., Nuutila P., Luotolahti M., et al. Insulin-induced increment of coronary flow reserve is not abolished by dexamethasone in healthy young men. J Clin Endocrinol Metab 85 (2000) 1868-1873
28. Sundell J., Laine H., Nuutila P., et al. The effects of insulin and short-term hyperglycemia on myocardial blood flow in young men with uncomplicated Type I diabetes. Diabetologia 45 (2002) 775-782
29. Sundell J., Laine H., Luotolahti M., et al. Blunted coronary vasoreactivity to insulin is an early alteration in hypertension. J Vasc Res 40 (2003) 58-67
30. Gaenzer H., Neumayr G., Marschang P., et al. Effect of insulin therapy on endothelium-dependent dilation in type 2 diabetes mellitus. Am J Cardiol 89 (2002) 431-434