A positive family history of premature coronary artery disease is associated with impaired endothelium-dependent coronary blood flow regulation

Circulation

Volumn 100, Issue 14, 1999, Pages 1502-1508

  Schächinger, Volker ^a   Britten, Martina B ^a   Elsner, Mathias ^a   Walter, Dirk H ^a   Scharrer, Inge ^a   Zeiher, Andreas M ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Abciximab; Angina; Thrombus; Troponin T; Unstable

Indexed keywords

ACETYLCHOLINE; ADENOSINE; PAPAVERINE;

ARTERY ENDOTHELIUM; ARTICLE; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; DOSE RESPONSE; FAMILY HISTORY; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; REGULATORY MECHANISM; RISK FACTOR;

EID: 0344562936     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.100.14.1502     Document Type: Article

References (31)

1. Zeiher AM. Endothelial vasodilator dysfunction: pathogenetic link to myocardial ischemia or epiphenomen. Lancet. 1996;348:s10-s12.
2. Chilian WM, Eastham CL, Marcus ML. Microvascular distribution of coronary vascular resistance in beating left ventricle. Am J Physiol. 1986;251:H779-H786.
3. Cannon ROI, Wattson RM, Rosing DR, Epstein SE. Angina caused by reduced vasodilator reserve of small coronary arteries. J Am Coll Cardiol 1983;1:1359-1373.
4. Zeiher AM, Krause T, Schächinger V, Minners J, Moser E. Impaired endothelium-dependent vasodilation of coronary resistance vessels is associated with exercise-induced myocardial ischemia. Circulation 1995; 91:2345-2352.
5. Zeiher AM, Drexler H, Saurbier B, Just H. Endothelium-mediated coronary blood flow modulation in humans. Effects of age, atherosclerosis, hypercholesterolemia, and hypertension. J Clin Invest. 1993;92:652-662.
6. Egashira K, Inou T, Hirooka Y, Yamada A, Maruoka Y, Kai H, Sugimachi M, Suzuki S, Takeshita A. Impaired coronary blood flow response to acetylcholine in patients with coronary risk factors and proximal atherosclerotic lesions. J Clin Invest. 1993;91:29-37.
7. Schächinger V, Zeiher AM. Alterations of coronary blood flow and myocardial perfusion in hypercholesterolemia. Heart, 1996;76:295-298.
8. Celermajer DS, Sorensen KE, Bull C, Robinson J, Deanfield JE. Endothelium-dependent dilation in the systemic arteries of asymptomatic subjects relates to coronary risk factors and their interaction. J Am Coll Cardiol. 1994;24:1468-1474.
9. Vita JA, Treasure CB, Nabel EG, McLenachan JM, Fish RD, Yeung AC, Vekshtein VI, Selwyn AP, Ganz P. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation. 1990;81:491-497.
10. Niebauer J, Cooke JP. Cardiovascular effects of exercise: role of endothelial shear stress. J Am Coll Cardiol. 1996;28:1652-1660.
11. Rudic RD, Shesely EG, Nobuyo M, Smithies O, Segal SS, Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest. 1998;101:731-736.
12. Schächinger V, Halle M, Minners J, Berg A, Zeiher AM. Lipoprotein(a) selectively impairs receptor-mediated endothelial vasodilator function of the human coronary circulation. J Am Coll Cardiol. 1997;30:927-934.
13. Zeiher AM, Drexler H, Wollschläger H, Just H. Endothelial dysfunction of the coronary microvasculature is associated with impaired coronary blood flow regulation in patients with early atherosclerosis Circulation 1991;84:1984-1992.
14. Schächinger V, Zeiher AM. Quantitative assessment of coronary vasoreactivity in humans in vivo: importance of baseline vasomotor tone in atherosclerosis. Circulation. 1995;2087-2094.
15. Lindpaintner K, Pfeffer MA, Kreutz R, Stampfer MJ, Grodstein F, LaMotte F, Buring J, Hennekens CH. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med. 1995;332:706-711.
16. Meredith IT, Yeung AC, Weidinger FF, Anderson TJ, Uehata A, Ryan TJ, Selwyn AP, Ganz P. Role of impaired endothelium-dependent vasodilation in ischemic manifestations of coronary artery disease. Circulation. 1993;87:V-56-V-66.
17. Egashira K, Inou T, Hirooka Y, Yamada A, Urabe Y, Takeshita A. Evidence of impaired endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary angiograms. N Engl J Med. 1993;328:1659-1664.
18. Langille BL, O'Donnell F. Reduction of arterial diameter produced by chronic decrease in blood flow are endothelium-dependent. Science. 1986;231:405-407.
19. Roger VL, Jacobson SJ, Pellikka PA, Miller TD, Bailey KR, Gersh BJ. Prognostic value of treadmill exercise testing. A population-based study in Olmsted county, Minesota. Circulation. 1998;98:2836-2841.
20. Cannon RO III, Curiel RV, Prasad A, Quyyumi AA, Panza JA. Comparison of coronary endothelial dynamics with electrocardiographic and left ventricular contractile responses to stress in the absence of coronary artery disease. Am J Cardiol. 1998;82:710-714.
21. Weiner DA, Ryan TJ, Parsons L, Fisher LD, Chaitmen BR, Sheffield LT, Tristani FE. Long-term prognostic value of exercise testing in men and women from the Coronary Artery Surgery Study (CASS) Registry. Am J Cardiol. 1995;75:865-870.
22. Mark DB, Hlatky MA, Harrell FE Jr, Lee KL, Califf RM, Pryor DB. Exercise treadmill score for predicting prognosis in coronary artery disease. Ann Intern Med. 1987;106:793-800.
23. Clarkson P, Celermajer DS, Powe AJ, Donald AE, Henry RM, Deanfield JE. Endothelium-dependent dilation is impaired in young healthy subjects with a family history of premature coronary disease. Circulation. 1997; 96:3378-3383.
24. Tiret L, Kee F, Poirier O, Nicaud V, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Amouyel P, Cambien F. Deletion polymorphism in the angiotensin-converting enzyme gene associated with parentaeral history of myocardial infarction. Lancet. 1993;991-992.
25. Celermajer DS, Sorensen KE, Barley J, Jeffrey J, Carter N, Deanfield JE. Angiotensin-converting enzyme genotype is not associated with endothelial dysfunction in subjects without other coronary risk factors. Atherosclerosis. 1994;111:121-126.
26. Malinow MR. Plasma homocyst(e)ine and arterial occlusive disease: a mini review. Clin Chem. 1995;41:173-176.
27. Verhoef P, Stampfer MJ. Prospective studies of homocysteine and cardiovascular disease. Nutr Rev. 1995;53:283-288.
28. Upchurch GR Jr, Welch GN, Fabian AJ, Freedman JE, Johnson JL, Keaney JFJ, Loscalzo J. Homocyst(e)ine decreases bioavailable nitric oxide by a mechanism involving gluthatione peroxidase. J Biol Chem. 1997;272:17012-17017.
29. Tawakol A, Omland T, Gerhard M, Wu JT, Creager MA. Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation. 1997;95:1119-1121.
30. Woo KS, Chook P, Lolin YI, Cheung ASP, Chan LT, Sun YY, Sanderson JE, Metreweli C, Celermajer DS. Hyperhomocyst(e)inemia is a risk factor for arterial endothelial dysfunction in humans. Circulation. 1997;96: 2542-2544.
31. Waller BF, Pinkerton CA, Slack JD. Intravascular ultrasound: a histological study of vessel during life. The new 'gold standard' for vascular imaging. Circulation. 1992;85:2305-2310.