메뉴 건너뛰기




Volumn 44, Issue 5, 2007, Pages 960-965

Incorporation of human complement C8 into the membrane attack complex is mediated by a binding site located within the C8β MACPF domain

Author keywords

C5b 7; C8 ; C8 ; C8 ; C8 ; Complement; Human C8; Membrane attack complex

Indexed keywords

COMPLEMENT COMPONENT C5B; COMPLEMENT COMPONENT C7; COMPLEMENT COMPONENT C8; COMPLEMENT COMPONENT C8 GAMMA; COMPLEMENT COMPONENT C8A; COMPLEMENT COMPONENT C8B; COMPLEMENT MEMBRANE ATTACK COMPLEX; UNCLASSIFIED DRUG;

EID: 33748771463     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.03.012     Document Type: Article
Times cited : (23)

References (26)
  • 1
    • 0021366920 scopus 로고
    • Function of subunits within the eighth component of human complement: selective removal of the γ chain reveals it has no direct role in cytolysis
    • Brickner A., and Sodetz J.M. Function of subunits within the eighth component of human complement: selective removal of the γ chain reveals it has no direct role in cytolysis. Biochemistry 23 (1984) 832-837
    • (1984) Biochemistry , vol.23 , pp. 832-837
    • Brickner, A.1    Sodetz, J.M.2
  • 2
    • 0021970820 scopus 로고
    • Functional domains of the α subunit of the eighth component of human complement: identification of a distinct binding site for the γ chain
    • Brickner A., and Sodetz J.M. Functional domains of the α subunit of the eighth component of human complement: identification of a distinct binding site for the γ chain. Biochemistry 24 (1985) 4603-4607
    • (1985) Biochemistry , vol.24 , pp. 4603-4607
    • Brickner, A.1    Sodetz, J.M.2
  • 3
    • 0024215620 scopus 로고
    • Membrane attack complex proteins C5b-6, C7, C8, and C9 of human complement
    • Esser A.F., and Sodetz J.M. Membrane attack complex proteins C5b-6, C7, C8, and C9 of human complement. Methods Enzymol. 162 (1988) 551-578
    • (1988) Methods Enzymol. , vol.162 , pp. 551-578
    • Esser, A.F.1    Sodetz, J.M.2
  • 4
    • 0028331322 scopus 로고
    • The membrane attack complex of complement: assembly structure and cytotoxic activity
    • Esser A.F. The membrane attack complex of complement: assembly structure and cytotoxic activity. Toxicology 87 (1994) 229-247
    • (1994) Toxicology , vol.87 , pp. 229-247
    • Esser, A.F.1
  • 5
    • 0344815737 scopus 로고
    • Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid
    • Hirel P.-H., Schmitter J.-M., Dessen P., Fayat G., and Blanquet S. Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 8247-8251
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 8247-8251
    • Hirel, P.-H.1    Schmitter, J.-M.2    Dessen, P.3    Fayat, G.4    Blanquet, S.5
  • 6
    • 0029060839 scopus 로고
    • Structure of the human C7 gene and comparison with the C6, C8A, C8B, and C9 genes
    • Hobart M.J., Fernie B.A., and DiScipio R.G. Structure of the human C7 gene and comparison with the C6, C8A, C8B, and C9 genes. J. Immunol. 154 (1995) 5188-5194
    • (1995) J. Immunol. , vol.154 , pp. 5188-5194
    • Hobart, M.J.1    Fernie, B.A.2    DiScipio, R.G.3
  • 7
    • 33748471302 scopus 로고    scopus 로고
    • Complement protein C8
    • Morikis D., and Lambris J.D. (Eds), Taylor and Francis, Boca Raton, FL
    • Lebioda L., and Sodetz J.M. Complement protein C8. In: Morikis D., and Lambris J.D. (Eds). Structural Biology of the Complement System (2005), Taylor and Francis, Boca Raton, FL 233-250
    • (2005) Structural Biology of the Complement System , pp. 233-250
    • Lebioda, L.1    Sodetz, J.M.2
  • 8
    • 0030431417 scopus 로고    scopus 로고
    • Invitro expression of the beta subunit of human complement component C8
    • Letson C.S., Kaufman K.M., and Sodetz J.M. Invitro expression of the beta subunit of human complement component C8. Mol. Immunol. 33 (1996) 1295-1300
    • (1996) Mol. Immunol. , vol.33 , pp. 1295-1300
    • Letson, C.S.1    Kaufman, K.M.2    Sodetz, J.M.3
  • 9
    • 0029095712 scopus 로고
    • Identity of the segment of human complement C8 recognized by complement regulatory protein CD59
    • Lockert D.H., Kaufman K.M., Chang C.P., Hüsler T., Sodetz J.M., and Sims P.J. Identity of the segment of human complement C8 recognized by complement regulatory protein CD59. J. Biol. Chem. 270 (1995) 19723-19728
    • (1995) J. Biol. Chem. , vol.270 , pp. 19723-19728
    • Lockert, D.H.1    Kaufman, K.M.2    Chang, C.P.3    Hüsler, T.4    Sodetz, J.M.5    Sims, P.J.6
  • 10
    • 0019861225 scopus 로고
    • Role of the beta subunit in interaction of the eighth component of human complement with the membrane-bound cytolytic complex
    • Monahan J.B., and Sodetz J.M. Role of the beta subunit in interaction of the eighth component of human complement with the membrane-bound cytolytic complex. J. Biol. Chem. 256 (1981) 3258-3262
    • (1981) J. Biol. Chem. , vol.256 , pp. 3258-3262
    • Monahan, J.B.1    Sodetz, J.M.2
  • 11
    • 0023890664 scopus 로고
    • Molecular organization and function of the complement system
    • Müller-Eberhard H.J. Molecular organization and function of the complement system. Annu. Rev. Biochem. 57 (1988) 321-347
    • (1988) Annu. Rev. Biochem. , vol.57 , pp. 321-347
    • Müller-Eberhard, H.J.1
  • 12
    • 0037125933 scopus 로고    scopus 로고
    • Interaction between the C8α-γ and C8β subunits of human complement C8: role of the C8β N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain
    • Musingarimi P., Plumb M.E., and Sodetz J.M. Interaction between the C8α-γ and C8β subunits of human complement C8: role of the C8β N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain. Biochemistry 41 (2002) 11255-11260
    • (2002) Biochemistry , vol.41 , pp. 11255-11260
    • Musingarimi, P.1    Plumb, M.E.2    Sodetz, J.M.3
  • 13
    • 0026643467 scopus 로고
    • The human complement regulatory protein CD59 binds to the α-chain of C8 and to the "b" domain of C9
    • Ninomiya H., and Sims P.J. The human complement regulatory protein CD59 binds to the α-chain of C8 and to the "b" domain of C9. J. Biol. Chem. 267 (1992) 13675-13680
    • (1992) J. Biol. Chem. , vol.267 , pp. 13675-13680
    • Ninomiya, H.1    Sims, P.J.2
  • 14
    • 0023664828 scopus 로고
    • The eighth component of human complement (C8): evidence that it is an oligomeric serum protein assembled from products of three different genes
    • Ng S.C., Rao A.G., Howard O.M., and Sodetz J.M. The eighth component of human complement (C8): evidence that it is an oligomeric serum protein assembled from products of three different genes. Biochemistry 26 (1987) 5229-5233
    • (1987) Biochemistry , vol.26 , pp. 5229-5233
    • Ng, S.C.1    Rao, A.G.2    Howard, O.M.3    Sodetz, J.M.4
  • 15
    • 0037018929 scopus 로고    scopus 로고
    • Crystal structure of human complement protein C8γ at 1.2 Å resolution reveals a lipocalin fold and a distinct ligand binding site
    • Ortlund E., Parker C.L., Schreck S.F., Ginell S., Minor W., Sodetz J.M., and Lebioda L. Crystal structure of human complement protein C8γ at 1.2 Å resolution reveals a lipocalin fold and a distinct ligand binding site. Biochemistry 41 (2002) 7030-7037
    • (2002) Biochemistry , vol.41 , pp. 7030-7037
    • Ortlund, E.1    Parker, C.L.2    Schreck, S.F.3    Ginell, S.4    Minor, W.5    Sodetz, J.M.6    Lebioda, L.7
  • 16
    • 0002706313 scopus 로고    scopus 로고
    • Proteins of the membrane attack complex
    • Volanakis J.E., and Frank M.M. (Eds), Marcel Dekker, New York, NY
    • Plumb M.E., and Sodetz J.M. Proteins of the membrane attack complex. In: Volanakis J.E., and Frank M.M. (Eds). The Human Complement System in Health and Disease (1998), Marcel Dekker, New York, NY 119-148
    • (1998) The Human Complement System in Health and Disease , pp. 119-148
    • Plumb, M.E.1    Sodetz, J.M.2
  • 17
    • 0033614780 scopus 로고    scopus 로고
    • Chimeric and truncated forms of human complement protein C8α reveal binding sites for C8β and C8γ within the membrane attack complex/perforin region
    • Plumb M.E., Scibek J.J., Barber T.D., Dunlap R.J., Platteborze P.L., and Sodetz J.M. Chimeric and truncated forms of human complement protein C8α reveal binding sites for C8β and C8γ within the membrane attack complex/perforin region. Biochemistry 38 (1999) 8478-8484
    • (1999) Biochemistry , vol.38 , pp. 8478-8484
    • Plumb, M.E.1    Scibek, J.J.2    Barber, T.D.3    Dunlap, R.J.4    Platteborze, P.L.5    Sodetz, J.M.6
  • 18
    • 0034711083 scopus 로고    scopus 로고
    • An indel within the C8α subunit of human complement component C8 mediates intracellular binding of C8γ and formation of C8α-γ
    • Plumb M.E., and Sodetz J.M. An indel within the C8α subunit of human complement component C8 mediates intracellular binding of C8γ and formation of C8α-γ. Biochemistry 39 (2000) 13078-13083
    • (2000) Biochemistry , vol.39 , pp. 13078-13083
    • Plumb, M.E.1    Sodetz, J.M.2
  • 19
    • 0021875717 scopus 로고
    • Purification of functional subunits of the eighth component of human complement (C8) under nondenaturing conditions
    • Rao A.G., and Sodetz J.M. Purification of functional subunits of the eighth component of human complement (C8) under nondenaturing conditions. Complement 1 (1984) 182-186
    • (1984) Complement , vol.1 , pp. 182-186
    • Rao, A.G.1    Sodetz, J.M.2
  • 20
    • 0031829918 scopus 로고    scopus 로고
    • Expression and characterization of recombinant subunits of human complement component C8: further analysis of the function of C8α and C8γ
    • Schreck S.F., Plumb M.E., Platteborze P.L., Kaufman K.M., Michelotti G.M., Letson C.S., and Sodetz J.M. Expression and characterization of recombinant subunits of human complement component C8: further analysis of the function of C8α and C8γ. J. Immunol. 161 (1998) 311-318
    • (1998) J. Immunol. , vol.161 , pp. 311-318
    • Schreck, S.F.1    Plumb, M.E.2    Platteborze, P.L.3    Kaufman, K.M.4    Michelotti, G.M.5    Letson, C.S.6    Sodetz, J.M.7
  • 22
    • 33748792313 scopus 로고    scopus 로고
    • Slade, D. J., Chiswell, B., Sodetz, J. M. Functional studies of the MACPF domain of human complement protein C8α reveal sites for simultaneous binding of C8β, C8γ and C9. Biochemistry, in press.
  • 23
    • 0019297965 scopus 로고
    • The eighth component of human complement: purification and physiochemical characterization of its unusual subunit structure
    • Steckel E.W., York R.G., Monahan J.B., and Sodetz J.M. The eighth component of human complement: purification and physiochemical characterization of its unusual subunit structure. J. Biol. Chem. 255 (1980) 11997-12005
    • (1980) J. Biol. Chem. , vol.255 , pp. 11997-12005
    • Steckel, E.W.1    York, R.G.2    Monahan, J.B.3    Sodetz, J.M.4
  • 24
    • 0021934073 scopus 로고
    • Analysis of the specific association of the eighth and ninth components of human complement: identification of a direct role for the α subunit of C8
    • Stewart J.L., and Sodetz J.M. Analysis of the specific association of the eighth and ninth components of human complement: identification of a direct role for the α subunit of C8. Biochemistry 24 (1985) 4598-4602
    • (1985) Biochemistry , vol.24 , pp. 4598-4602
    • Stewart, J.L.1    Sodetz, J.M.2
  • 25
    • 4644327017 scopus 로고    scopus 로고
    • Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5
    • Thai C.-T., and Ogata R.T. Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5. J. Immunol. 173 (2004) 4547-4552
    • (2004) J. Immunol. , vol.173 , pp. 4547-4552
    • Thai, C.-T.1    Ogata, R.T.2
  • 26
    • 18644370595 scopus 로고    scopus 로고
    • Recombinant C345C and factor I modules of complement components C5 and C7 inhibit C7 incorporation into the complement membrane attack complex
    • Thai C.-T., and Ogata R.T. Recombinant C345C and factor I modules of complement components C5 and C7 inhibit C7 incorporation into the complement membrane attack complex. J. Immunol. 174 (2005) 6227-6322
    • (2005) J. Immunol. , vol.174 , pp. 6227-6322
    • Thai, C.-T.1    Ogata, R.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.