Expression and colocalization of NADPH-diaphorase and Fos in the subnuclei of the parabrachial nucleus in rats following visceral noxious stimulation

Brain Research

Volumn 1114, Issue 1, 2006, Pages 41-52

  Li, Lei ^a   Ding, Jiong ^a   Ren, Zijian ^a   Han, Qunying ^a   Hu, Gang ^a   Xiao, Ming ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Central nucleus of amygdala; Fos; nNOS; Parabrachial nucleus; Rat; Visceral noxious stimulation

Indexed keywords

BIOLOGICAL MARKER; FORMALDEHYDE; NITRIC OXIDE SYNTHASE; PROTEIN FOS; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN MAPPING; BRAIN REGION; CELL COUNT; CELL FUNCTION; CELL LABELING; COMPARATIVE STUDY; CONTROLLED STUDY; HISTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INJECTION; MALE; NOCICEPTIVE STIMULATION; NONHUMAN; OBSERVATION; PARABRACHIAL NUCLEUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SIGNAL PROCESSING; STOMACH; VISCERAL PAIN;

ANALYSIS OF VARIANCE; ANIMALS; FORMALDEHYDE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; MEDULLA OBLONGATA; NADPH DEHYDROGENASE; NEURAL PATHWAYS; NEURONS; ONCOGENE PROTEINS V-FOS; PAIN; PHYSICAL STIMULATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33748764153     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.07.042     Document Type: Article

References (44)

1. Altschuler S.M., Bao X.M., Bieger D., Hopkins D.A., and Miselis R.R. Viscerotopic representation of the upper alimentary tract in the rat: sensory ganglia and nuclei of the solitary and spinal trigeminal tracts. J. Comp. Neurol. 283 (1989) 248-268
2. Bernard J.F., Alden M., and Besson J.M. The organization of the efferent projections from the pontine parabrachial area to the amygdaloid complex: a Phaseolus vulgaris leucoagglutinin (PHA-L) study in the rat. J. Comp. Neurol. 329 (1993) 201-229
3. Bernard J.F., Huang G., and Besson J. The parabrachial area: electrophysiological evidence for an involvement in visceral nociceptive processes. J. Neurophysiol. 71 (1994) 1646-1660
4. Berthoud H.R., Blackshaw L.A., Brookes S.J., and Grundy D. Neuroanatomy of extrinsic afferents supplying the gastrointestinal tract. Neurogastroenterol. Motil. 16 (2004) S28-S33
5. Chamberlin N.L., and Saper C.B. Topographic organization of cardiovascular responses to electrical and glutamate microstimulation of the parabrachial nucleus in the rat. J. Comp. Neurol. 326 (1992) 245-262
6. Chen T., Dong Y.X., and Li Y.Q. Fos expression in serotonergic neurons in the rat brainstem following noxious stimuli: an immunohistochemical double-labelling study. J. Anat. 203 (2003) 579-588
7. Dawson T.M., Bredt D.S., Fotuhi M., Hwang P.M., and Snyder S.H. Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 7797-7801
8. Dawson T.M., Dawson V.L., and Snyder S.H. A novel neuronal messenger molecule in brain: the free radical, nitric oxide. Ann. Neurol. 32 (1992) 297-311
9. Dong Y.X., Han Z.A., Xiong K.H., and Rao Z.R. Fos expression in serotonergic midbrain neurons projecting to the paraventricular nucleus of hypothalamus after noxious stimulation of the stomach: a triple labeling study in the rat. Neurosci. Res. 27 (1997) 155-160
10. Feil K., and Herbert H. Topographic organization of spinal and trigeminal somatosensory pathways to the rat parabrachial and Kolliker-Fuse nuclei. J. Comp. Neurol. 353 (1995) 506-528
11. Fulwiler C., and Saper C. Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brain Res. Rev. 7 (1984) 229-259
12. Garbossa D., Fontanella M., Tomasi S., Ducati A., and Vercelli A. Differential distribution of NADPH-diaphorase histochemistry in human cerebral cortex. Brain Res. 1034 (2005) 1-10
13. Grundy D. Neuroanatomy of visceral nociception: vagal and splanchnic afferent. Gut 51 (2002) S2-S5
14. Guo Z.L., Moazzami A.R., and Longhurst J.C. Stimulation of cardiac sympathetic afferents activates glutamatergic neurons in the parabrachial nucleus: relation to neurons containing nNOS. Brain Res. 1053 (2005) 97-107
15. Harris J.A. Using c-fos as a neural marker of pain. Brain Res. Bull. 45 (1998) 1-8
16. Herbert H., Moga M.M., and Saper C.B. Connections of the parabrachial nucleus with the nucleus of the solitary tract and the medullary reticular formation in the rat. J. Comp. Neurol. 293 (1990) 540-580
17. Hermanson O., and Blomqvist A. Subnuclear localization of FOS-like immunoreactivity in the rat parabrachial nucleus after nociceptive stimulation. J. Comp. Neurol. 368 (1996) 45-56
18. Hope B.T., Michael G.J., Knigge K.M., and Vincent S.R. Neuronal NADPH-diaphorase is a nitric oxide synthase. Proc. Natl. Acad. Sci. U. S. A. 88 (1991) 2811-2814
19. Jaing W. Neurobiology of visceral afferent neurons: neuroanatomy, functions, organ regulations and sensations. Biol. Psychol. 42 (1996) 29-51
20. Jhamandas J.H., Petrov T., Harris K.H., Vu T., and Krukoff T.L. Parabrachial nucleus projection to the amygdala in the rat: electrophysiological and anatomical observations. Brain Res. Bull. 39 (1996) 115-126
21. Jia H.G., Rao Z.R., and Shi J.W. An indirect projection from the nucleus of the solitary tract to the central nucleus of the amygdala via the parabrachial nucleus in the rat: a light and electron microscopic study. Brain Res. 663 (1994) 181-190
22. Karimnamazi H., Travers P.S., and Travers J.B. Oral and gastric input to the parabrachial nucleus of the rat. Brain Res. 957 (2002) 193-206
23. Mizusawa A., Ogawa H., Kikuchi Y., Hida W., and Shirato K. Role of the parabrachial nucleus in ventilatory responses of awake rats. J. Physiol. 489 (1995) 877-884
24. Morgan J.I., and Curran T. Stimulus-transcription coupling in neurons: role of cellular immediate-early genes. Trends Neurosci. 12 (1989) 459-462
25. Neugebauer V., Li W., Bird G.C., and Han J.S. The amygdala and persistent pain. Neuroscientist 10 (2004) 221-234
26. Nishijo H., and Norgren R. Responses from parabrachial gustatory neurons in behaving rats. J. Neurophysiol. 63 (1990) 707-724
27. Norgren R., and Smith G.P. Central distribution of subdiaphragmatic vagal branches in the rat. J. Comp. Neurol. 273 (1988) 207-223
28. Paloff A.M., and Hinova-Palova D.V. Topographical distribution of NADPH-diaphorase positive neurons in the cat's inferior colliculus. J. Hirnforsch. 39 (1998) 231-243
29. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1986), Academic Press, New York fig. 52-58
30. Phelps E.A., and LeDoux J.E. Contributions of the amygdala to emotion processing: from animal models to human behavior. Neuron 48 (2005) 175-187
31. Richard S., Engblom D., Paues J., Mackerlova L., and Blomqvist A. Activation of the parabrachio-amygdaloid pathway by immune challenge or spinal nociceptive input: a quantitative study in the rat using Fos immunohistochemistry and retrograde tract tracing. J. Comp. Neurol. 481 (2005) 210-219
32. Rodella L., Rezzani R., Gioia M.M., Tredici G., and Bianchi R. Expression of Fos immunoreactivity in the rat supraspinal regions following noxious visceral stimulation. Brain Res. Bull. 47 (1998) 357-366
33. Rodrigo J., Springall D.R., Uttenthal O., Bentura M.L., Abadia-Molina F., Riveros-Moreno V., Martinez-Murillo R., Polak J.M., and Moncada S. Localization of nitric oxide synthase in the adult rat brain. Philos. Trans. R. Soc. Lond., B Biol. Sci. 345 (1994) 175-221
34. Saleh T.M., and Connell B.J. Modulation of the cardiac baroreflex following reversible blockade of the parabrachial nucleus in the rat. Brain Res. 767 (1997) 201-207
35. Salter M., Strijbos P.J., Neale S., Duffy C., Follenfant R.L., and Garthwaite J. The nitric oxide-cyclic GMP pathway is required for nociceptive signalling at specific loci within the somatosensory pathway. Neuroscience 73 (1996) 649-655
36. Saper C.B., Loewy A.D., and Roberts M.H. Efferent connections of the parabrachial nucleus in the rat. Brain Res. 197 (1980) 291-317
37. Schmidt H.H.W., Lohmann S.M., and Walter U. The nitric oxide and c-GMP signal transduction system: regulation and mechanism of action. Biochim. Biophys. Acta 1178 (1993) 153-175
38. Schuligoi R., Herzeg G., Wachter C., Jocic M., and Holzer P. Differential expression of c-fos messenger RNA in the rat spinal cord after mucosal and serosal irritation of the stomach. Neuroscience 72 (1996) 535-544
39. Schuligoi R., Jocic M., Heinemann A., Schoninkle E., Pabst M.A., and Holzer P. Gastric acid-evoked c-fos messenger RNA expression in rat brainstem is signaled by capsaicin-resistant vagal afferents. Gastroenterology 115 (1998) 649-660
40. Schuman E.M., and Madison D.V. Nitric oxide and synaptic function. Annu. Rev. Neurosci. 17 (1994) 153-183
41. Slugg R.M., and Light A.R. Spinal cord and trigeminal projections to the pontine parahrachial region in the rat as demonstrated with Phaseolus vulgaris-leucoagglutinin. J. Comp. Neurol. 339 (1994) 49-61
42. Takeuchi Y., Xie Q., Miki T., Matsumoto Y., Satriotomo I., Li H.P., and Gu H. Parabrachial inputs to Fos-immunoreactive neurons in the lateral central nucleus of amygdala activated by hypotension: a light and electron microscopic study in the rat. Brain Res. Bull. 64 (2004) 171-180
43. Traub R.J., Sengupta J.N., and Gebhart G.F. Differential c-fos expression in the nucleus of the solitary tract and spinal cord following noxious gastric distention in the rat. Neuroscience 74 (1996) 873-884
44. Xiao W.S., and Peng Y.X. Expression and localization of c-Fos and NOS in the central nerve system following esophageal acid stimulation in rats. World J. Gastroenterol. 10 (2004) 2287-2291