Fos expression in serotonergic midbrain neurons projecting to the paraventricular nucleus of hypothalamus after noxious stimulation of the stomach: A triple labeling study in the rat

Neuroscience Research

Volumn 27, Issue 2, 1997, Pages 155-160

  Dong, Yuan Xiang ^a   Han, Zhi An ^a   Xiong, Kang Hui ^a   Rao, Zhi Ren ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Fos; Paraventricular nucleus of hypothalamus; Periaqueductal gray; Rat; Serotonin

Indexed keywords

FORMALDEHYDE; HORSERADISH PEROXIDASE; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; GENE EXPRESSION; HISTOCHEMISTRY; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MESENCEPHALON; NOCICEPTIVE STIMULATION; NONHUMAN; ONCOGENE C FOS; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; SEROTONINERGIC NERVE CELL; STOMACH; THALAMUS MIDLINE NUCLEUS;

ANIMALS; GENE EXPRESSION; GENES, FOS; HISTOCYTOCHEMISTRY; HORSERADISH PEROXIDASE; MALE; MESENCEPHALON; NEURAL PATHWAYS; NEURONS; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PERIAQUEDUCTAL GRAY; PHYSICAL STIMULATION; RAPHE NUCLEI; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; STOMACH;

EID: 0030965466     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(96)01143-1     Document Type: Article

References (14)

1. Basbaum, A.I. and Fields, H.L. (1984) Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Ann. Rev. Neurosci., 7: 309-338.
2. Berk, M.L. and Finkelstein, J.A. (1981) Afferent projections to the preoptic area and hypothalamic regions in the rat brain. Neuroscience, 6: 1601-1624.
3. Björklund, A., Hökfelt, T. and Swanson, L.W. (1987) Integrated systems of the CNS, Part. I., hypothalamus, hippocampus, amygdala, retina, Handbook of Chemical Neuroanatomy, Vol. 5, Elsevier Press, Amsterdam, pp. 1-124.
4. Chen, L.W., Jin, G.R., Rao, Z.R. and Shi, J.W.(1993) C-fos expression within central nervous system of the rat following gastrointestinal visceral noxious stimulation. Chin. J. Neuroanat., 9: 185-191.
5. Chen, L.W., Rao, Z.R. and Shi, J.W.(1995) Catecholaminergic neurons in the nucleus tractus solitarii which send their axons to the midbrain periaqueductal gray express Fos protein after noxious stimulation of the stomach: a triple labeling study in the rat. Neurosci. Lett., 189: 179-181.
6. Hsu, S-M., Raine, L. and Fanger, H.(1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem, Cytochem., 29: 577-580.
7. Keay, K.A., Clement, C.I., Owler, B., Depaulis, A. and Bandler,R. (1994) Convergence of deep somatic and visceral nociceptive information onto a discrete ventrolateral midbrain periaqueductal gray region. Neuroscience, 61: 727-732.
8. Li, Y.-Q., Zeng, S.-L., Dong, Y.-X., Rao, Z.-R. and Shi, J.-W.(1991) Serotonin-, substance P- and tyrosine hydroxylase-like immunoreactive neurons projecting from the periaqueductal gray to the ventromedial hypothalamic nucleus in the rat. Neurosci. Lett., 134: 33-36.
9. Mantyh, P.W. (1983) Connections of midbrain periaqueductal gray in the monkey. I. Ascending efferent projections. J. Neurophysiol., 49: 567-581.
10. Paxions, G. and Watson, C. (1986) The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, Sydney.
11. Rao, Z.-R., Chen, L.-W., Jin, G.-R., Han, Z.-A., Dong, Y.-X, Xiong, K.H. and Shi, J.W. (1994) Simultaneous demonstration of Fos protein, tyrosine hydroxylase (TH) and HRP retrograde labeling in same neurons - A triple labeling technique. Acta. Anat. Sinca., 25: 219-223.
12. Sawchenko, P.E., Swanson, L.W., Steinbusch, H.W.M. and Verhofstad, A.A.J.(1983) The distribution and cells of origin of serotonergic inputs to the paraventricular and supraoptic nuclei of the rat. Brain Res., 277: 355-360.
13. Shu, S.-Y., Ju, G. and Fan, L.Z. (1988) The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system. Neurosci. Lett., 85: 169-173.
14. Steinbusch, H.W.M. (1981) Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. Neuroscience, 6: 557-618.