Neurobiology of visceral afferent neurons: Neuroanatomy, functions, organ regulations and sensations

Biological Psychology

Volumn 42, Issue 1-2, 1996, Pages 29-51

  Jänig, Wilfrid ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Encoding of visceral events; Reflexes; Regulations; Sensations; Spinal; Vagal; Visceral afferent neurons

Indexed keywords

CENTRAL NERVOUS SYSTEM; HUMAN; MEDULLA OBLONGATA; NEUROANATOMY; NEUROBIOLOGY; PRIORITY JOURNAL; REFLEX; REVIEW; SENSATION; SENSORY NERVE; SPINAL CORD DORSAL HORN; VAGUS NERVE; VISCERA; VISCERAL PAIN;

EID: 0342502274     PISSN: 03010511     EISSN: None     Source Type: Journal    
DOI: 10.1016/0301-0511(95)05145-7     Document Type: Article

References (102)

1. Andrews, P.L.R. (1986). Vagal afferent innervation of the gastrointestinal tract. In F. Cervero, & J.F.B. Morrison (Eds.). Visceral sensation. Progress in Brain Research, 67, 65-86.
2. Bahns, E., Ernsberger, U., Jänig, W., & Nelke, A. (1986a). Functional characteristics of lumbar visceral afferent fibres from the urinary bladder and the urethra in the cat. Pflügers Archiv, 407, 510-518.
3. Bahns, E., Ernsberger, U., Jänig, W., & Nelke, A. (1986b). Discharge properties of mechanosensitive afferents supplying the retroperitoneal space. Pflügers Archiv, 407, 519-525.
4. Bahns, E., Halsband, U., & Jänig, W. (1987). Responses of sacral visceral afferents from the lower urinary tract, colon and anus to mechanical stimulation. Pflügers Archiv, 410, 296-303.
5. Baker, D.G., Coleridge, H.M., Coleridge, J.C.G., & Nerdrum, T. (1980). Search for a cardiac nociceptor: stimulation by bradykinin of sympathetic afferent nerve endings in the heart of the cat. Journal of Physiology, 306, 519-536.
6. Barnes P.J. (1991). Sensory nerves, neuropeptides, and asthma. Annals of the New York Academy of Sciences, 629, 359-370.
7. Baumann, T.K., Simone, D.A., Shain, C.N., & LaMotte, R.H. (1991). Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia. Journal of Neurophysiology, 66, 212-227.
8. Blumberg, H., Haupt, P., Jänig, W., & Kohler, W. (1983). Encoding of visceral noxious stimuli in the discharge patterns of visceral afferent fibres from the colon. Pflügers Archiv, 398, 33-40.
9. Cannon, B. (1933). A method of stimulating autonomic nerves in the unanesthetized cat with observation on the motor and sensory effects. American Journal of Physiology, 105, 366-372.
10. Cervero, F. (1982). Afferent activity evoked by natural stimulation of the biliary system in the ferret. Pain, 13, 137-151.
11. Cervero, F. (1994). Sensory innervation of the viscera: peripheral basis of visceral pain. Physiological Reviews, 75, 95-138.
12. Cervero, F., & Jänig, W. (1992). Visceral nociceptors: a new world order? Trends in Neuroscience, 15, 374-378.
13. Cervero, F., & Morrison, J.F.B. (Eds.) (1986). Visceral sensation. Progress in Brain Research, 67.
14. Cervero, F., & Sann, H. (1989). Mechanically evoked responses of afferent fibres innervating the guinea-pig's ureter: an in vitro study. Journal of Physiology, 412, 245-266.
15. Cervero, F., & Tattersall, J.E.H. (1986). Somatic and visceral sensory integration in the thoracic spinal cord. In F. Cervero, & J.F.B. Morrison, (Eds.). Visceral sensation, Progress in Brain Research, 67, 189-205.
16. Coleridge, H.M., & Coleridge J.C.G. (1980). Cardiovascular afferents involved in regulation of peripheral resistance. Annual Reviews of Physiology, 42, 413-427.
17. Coleridge, J.C.G., & Coleridge, H.M. (1984). Afferent vagal C-fibre innervation of the lungs and airways and its functional significance. Reviews of Physiology, Biochemistry and Pharmacology, 99, 1-110.
18. Davis, K.D., Meyer, R.A., & Campbell, J.N. (1993). Chemosensitivity and sensitization of nociceptive afferents that innervate the hairy skin of monkey. Journal of Neurophysiology, 69, 1071-1081.
19. de Groat, W.C. (1986). Spinal cord projections and neuropeptides in visceral afferent neurons. Progress in Brain Research, 67, 165-187.
20. de Groat, W.C. (1987). Neuropeptides in pelvic afferent pathways. Experientia, 43, 801-813.
21. de Groat, W.C. (1989). Neuropeptides in pelvic afferent pathways. In J.M. Polak (Ed.). Regulatory peptides (pp. 334-361). Basel: Birkhauser Verlag A.G.
22. de Groat, W.C., & Booth, A.M. (1993). Neural control of penile erection. In C.A. Maggi (Ed.). Nervous control of the urogenital system (pp. 467-524). Vol. 2 of Burnstock G. (Ed.) The autonomic nervous system. Chur Switzerland: Harwood Academic Publishers.
23. de Groat, W.C., Booth, A.M., & Yoshimura, N. (1993). Neurophysiology of micturition and its modification in animal models in human disease. In C.A. Maggi (Ed.). Nervous control of the urogenital system (pp. 227-290). Vol. 2 of Burnstock G. (Ed.) The autonomic nervous system. Chur Switzerland, Harwood Academic Publishers.
24. DiBona, G.F. (1982). The functions of the renal nerves. Reviews of Physiology, Biochemistry and Pharmacology, 94, 75-181.
25. Dockray, G.J., Green, T., & Varro, A. (1989). The afferent peptidergic innervation of the upper gastrointestinal tract. In M.V. Singer, & A. Goebel (Eds.). Nerves and the gastrointestinal tract (pp. 105-122). Boston, The Hague, Dordrecht, Lancaster: MTP Press Ltd, Kluwer Academic Publishers.
26. Droste, C., & Roskamp, H. (1990). Pain perception and endogenous pain modulation in angina pectoris. Advances in Cardiology, 37, 142-164.
27. Ferguson, M.L., & Katkin, E.S. (1995). Visceral perception, anhedonia, and emotion. Biological Psychology, 42, 131-145.
28. Foerster, O. (1927). Die Leitungsbahnen des Schmerzgefühls und die chirurgische Behandlung der Schmerzzustände. Berlin, Wien: Urban und Schwarzenberg.
29. Foreman, R.D. (1989). Organization of the spinothalamic tract as a relay for cardiopulmonary sympathetic afferent fiber activity. Progress in Sensory Physiology, 9, 1-51.
30. Furness, J.B., & Costa, M. (1987). The enteric nervous system. Edinburgh: Churchill Livingstone.
31. Gebhart, G.F., & Randich, A. (1992). Vagal modulation of nociception. American Pain Society Journal, 1, 26-32.
32. Gonella, J., Bouvier, M., & Blanquet, F. (1987). Extrinsic nervous control of motility of small and large intestines and related sphincters. Physiological Reviews, 67, 902-961.
33. Grigg, P., Schaible, H.G., & Schmidt, R.F. (1986). Mechanical sensitivity of group III and IV afferents from posterior articular nerve in normal and inflamed cat knee. Journal of Neurophysiology, 55, 635-643.
34. Grundy, D. (1988). Speculation on the structure/function relationship for vagal and splanchnic afferent endings supplying the gastrointestinal tract. Journal of the Autonomic Nervous System, 22, 175-180.
35. Grundy, D., & Scratcherd, T. (1989). Sensory afferents from the gastrointestinal tract. In J.D. Wood (Ed.). Handbook of physiology, the gastrointestinal system I (pp. 593-620). Baltimore: American Physiological Society.
36. Guyenet, P.G. (1990). Role of the ventral medulla oblongata in blood pressure regulation. In A.D. Loewy, & K.M. Spyer (Eds.). Central regulation of autonomic functions (pp. 145-167). New York, Oxford: Oxford University Press.
37. Häbler, H.-J., Jänig, W., & Koltzenburg, M. (1990). Activation of unmyelinated afferent fibres by mechanical stimuli and inflammation of the urinary bladder in the cat. Journal of Physiology, 425, 545-562.
38. Häbler, H.-J., Jänig, W., & Koltzenburg, M. (1993a). Myelinated primary afferents of the sacral spinal cord responding to slow filling and distension of the urinary bladder. Journal of Physiology, 463, 449-460.
39. Häbler, H.-J., Jänig, W., & Koltzenburg, M. (1993b). Receptive properties of myelinated afferents innervating the inflamed urinary bladder. Journal of Neurophysiology, 69, 395-405.
40. Handwerker, H.O., Kilo, S., & Reeh, P.W. (1991). Unresponsive afferent nerve fibres in the nerve of the rat. Journal of Physiology, 435, 229-242.
41. Haupt, P., Jänig, W., & Kohler, W. (1983). Response pattern of visceral afferent fibres supplying the colon upon chemical and mechanical stimuli. Pflügers Archiv, 398, 41-47.
42. Hertz, A.F. (1911). The sensibility of the alimentary canal. Oxford: Oxford University Press.
43. Jänig, W. (1985). Organization of the lumbar sympathetic outflow to skeletal muscle and skin of the cat hindlimb and tail. Reviews of Physiology, Biochemistry and Pharmacology, 102, 119-213.
44. Jänig, W. (1986). Spinal cord integration of visceral sensory systems and sympathetic nervous system reflexes. In F. Cervero, & J.F.B. Morrison (Eds.). Visceral sensation. Progress in Brain Research, 67, 255-277.
45. Jänig, W. (1988). Integration of gut function by sympathetic reflexes through the spinal cord and the prevertebral ganglia. In D. Grundy, & N.W. Read (Eds.). Ballière's clinical gastroenterology, vol. 2 (pp. 45-62). London: Balliere Tindall, Academic Press.
46. Jänig, W. (1995). Ganglionic transmission in vivo. In E.M. McLachlan (Ed.). Autonomic ganglia (pp. 349-395), vol. 6 of Burnstock, G. (Ed.). The autonomic nervous system. Chur, Switzerland: Harwood Academic Publishers.
47. Jänig W., & Häbler, H.-J. (1995). Visceral-autonomic integration. In G.F. Gebhart (Ed.). Visceral pain. Progress in pain research and management, vol. 4 (pp. 311-348). Seattle: IASP Press.
48. Jänig, W., & Koltzenburg, M. (1990). The function of spinal primary afferents supplying colon and urinary bladder. Journal of the Autonomic Nervous System, 30, S89-S96.
49. Jänig, W., & Koltzenburg, M. (1991). Receptive properties of sacral primary afferent neurons supplying the colon. Journal of Neurophysiology, 65, 1067-1077.
50. Jänig, W., & Koltzenburg, M. (1993). Pain arising in the urogenital tract. In C.A. Maggi (Ed.). Nervous control of the urogenital system. Vol. 2 of Burnstock G. (Ed.) The autonomic nervous system (pp. 523-576). Chur, Switzerland: Harwood Academic Publishers.
51. Jänig, W., & McLachlan, E.M. (1987). Organization of lumbar spinal outflow to the distal colon and pelvic organs. Physiological Reviews, 67, 1332-1404.
52. Jänig, W., & McLachlan, E.M. (1992). Characteristics of function-specific pathways in the sympathetic nervous system. Trends in Neuroscience, 15, 475-481.
53. Jänig, W., & Morrison, J.F.B. (1986), Functional properties of spinal visceral afferents supplying abdominal and pelvic organs with special emphasis on visceral nociception. In F. Cervero and J.F.B. Morrison (Eds.). Visceral sensation. Progress in Brain Research, 67, 87-114.
54. Jänig, W., Schmidt, M., Schnitzler, A., & Wesselmann, U. (1991). Differentiation of sympathetic neurones projecting in the hypogastric nerves in terms of their discharge patterns in cats. Journal of Physiology, 437, 157-179.
55. James, W., & Lange, C.G. (1920). The emotions. Baltimore: Williams and Wilkins.
56. Koltzenburg, M., & McMahon, S.B. (1986). Plasma extravasation in the rat urinary bladder following mechanical, electrical and chemical stimuli: evidence for a new population of chemosensitive primary sensory afferents. Neuroscience Letters, 72, 352-356.
57. Kopp, U.C., & DiBona, G.F. (1992). The neural control of renal function. In D.W. Seldin, & G. Giebisch (Eds.). The kidney: physiology and pathophysiology 2nd edition (pp. 1157-1204). New York: Raven Press.
58. Kress, M., Koltzenburg, M., Reeh, P.W., & Handwerker, H.O. (1992). Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro. Journal of Neurophysiology, 68, 581-595.
59. Kumazawa, T. (1990). Functions of the nociceptive primary neurons. Japanese Journal of Physiology, 40, 1-14.
60. LaMotte, R.H., Lundberg, L.F.R., & Torebjörk, H.E. (1992). Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin. Journal of Physiology, 448, 749-764.
61. Lewin, G.R., & McMahon, S.B. (1993). Muscle afferents innervating skin form somatotopically appropriate connections in the adult rat dorsal horn. European Journal of Neuroscience, 5, 1083-1092.
62. Loewy, A.D., & Spyer, K.M. (Eds.) (1990). Central regulation of autonomic functions. New York, Oxford: Oxford University Press.
63. Lombardi, F., Della Bella, P., Casati, R., & Malliani, A. (1981). Effects of intracoronary administration of bradykinin on the impulse activity of afferent sympathetic unmyelinated fibers with left ventricular endings in the cat. Circulation Research, 48, 69-75.
64. Lundberg, J.M., Brodin, E., Hua, X., & Saria, A. (1984). Vascular permeability changes and smooth muscle contraction in relation to capsaicin-sensitive substance P afferents in the guinea-pig. Acta Physiologica Scandinavica, 120, 217-227.
65. Lundgren, O. (1989). Enteric nervous control of mucosal functions of the small intestine in vivo. In M.V. Singer, & A. Goebel (Eds.). Nerves and the gastrointestinal tract (pp. 275-285). Lancaster, Boston, The Hague, Dordrecht: MTP Press Limited.
66. Maggi, C.A. (Ed.) (1993). Nervous control of the urogenital system. Vol. 2 of G. Burnstock (Ed.) The autonomic nervous system. Chur, Switzerland: Harwood Academic Publishers.
67. Maggi, C.A., & Meli, A. (1988). The sensory-efferent function of capsaicin-sensitive sensory neurons. General Pharmacology, 119, 1-43.
68. Malliani, A. (1982). Cardiovascular sympathetic afferent fibers. Reviews of Physiology, Biochemistry and Pharmacology, 94, 11-74.
69. Malliani, A. (1986). The elusive link between transient myocardial ischemia and pain. Circulation, 73, 201-204.
70. Malliani, A., & Lombardi, F. (1982). Consideration of the fundamental mechanisms eliciting cardiac pain. American Heart Journal, 103, 575-578.
71. Mayer, E.A., & Raybould, H.E. (Eds.) (1993). Basic and clinical aspects of chronic abdominal pain. Pain research and clinical management vol. 9. Amsterdam: Elsevier Publishers B.V.
72. McDonald, D.M. (1990), The ultrastructure and permeability of tracheobronchial blood vessels in health and disease. European Respiratory Journal, Suppl. 12, 572s-585s.
73. Mei, N. (1983). Sensory structures in the viscera. Progress in sensory physiology. vol. 4. (pp. 1-42). Berlin, Heidelberg: Springer Verlag.
74. Mei, N. (1985). Intestinal chemosensitivity. Physiological Reviews, 65, 211-237.
75. Mehler, S.T., & Gebhart, G.F. (1992). A critical review of the afferent pathways and the potential chemical mediators involved in cardiac pain. Neuroscience, 48, 501-524.
76. Meyer, R.A., Campbell, J.N., & Raja, S.N. (1994). Peripheral neural mechanisms of nociception. In P.D. Wall, & R. Melzack (Eds.). Textbook of pain (pp. 13-44). Edinburgh: Churchill Livingstone.
77. Meyers, G.E. (1986). William James, his life and thought. New Haven, CT: Yale University Press.
78. Michaelis, M., Göder, R., Häbler, H.-J., & Jänig, W. (1994). Properties of afferent nerve fibres supplying the saphenous vein in the cat. Journal of Physiology, 474, 233-243.
79. Myrtek, M., Fichtler, A., König, K., Brügner, G., & Müller, W. (1994). Differences between patients with asymptomatic and symptomatic myocardial infarction; the relevance of psychological factors. European Heart Journal, 15, 311-317.
80. Ochoa, J.L., & Torebjörk, H.E. (1983). Sensations evoked by intraneural microstimulation of single mechanoreceptor units innervating the human hand. Journal of Physiology, 342, 633-645.
81. Ochoa, J., & Torebjörk, E. (1989). Sensations evoked by intraneural microstimulation of C nociceptor fibres in human skin nerves. Journal of Physiology, 415, 583-599.
82. Paintal, A.S. (1986). The visceral sensations - some basic mechanisms. In F. Cervero, & J.F.B. Morrison (Eds.). Visceral sensation. Progress in Brain Research, 67, 3-19.
83. Randich, A., & Gebhart, G.F. (1992). Vagal afferent modulation of nociception. Brain Research Reviews, 17, 77-99.
84. Recordati, G., Moss, N.G., Genovesi, S., & Rogenes, P. (1981). Renal chemoreceptors. Journal of the Autonomic Nervous System, 3, 237-251.
85. Ritter, S., Ritter, R.C., & Barnes, C.D. (Eds.) (1992). Neuroanatomy and physiology of abdominal vagal afferents. Boca Raton, Ann Arbor: CRC Press.
86. Schaible, H.-G., & Schmidt, R.F. (1988). Time course of mechanosensitivity changes in articular afferents during a developing experimental arthritis. Journal of Neurophysiology, 60, 2180-2195.
87. Schmidt, R.F., & Thews, G. (Eds.) (1989). Human physiology, 2nd Ed. Berlin, Heidelberg, New York: Springer Verlag.
88. Sengupta, J.N., Kauvar, D., & Goyal, R.K. (1989). Characteristics of vagal esophageal tension-sensitive afferent fibers in the opossum, Journal of Neurophysiology, 61, 1001-1010.
89. Sengupta, J.N., Saha, J.K., & Goyal, R.K. (1990). Stimulus-response function studies of esophageal mechanosenative nociceptors in sympathetic afferents of opposum. Journal of Neurophysiology, 64, 796-812.
90. Sherrington, C.S. (1900). Cutaneous sensation. In E.A. Schäfer (Ed.). Textbook of physiology, vol. 2 (pp. 920-1001). Edinburgh, London: Young J. Pentland.
91. Sherrington, C.S. (1906). The integrative action of the nervous system, 2nd edition, 1947. New Haven, CT: Yale University Press.
92. Simone, D.A., Baumann, T.K., & LaMotte, R.H. (1989). Dose-dependent pain and mechanical hyperalgesia in humans after intradermal injection of capsaicin. Pain, 38, 99-108.
93. Simone, D.L., Sorkin, L.S., Oh, U., Chung, J.M., Owens, C., LaMotte, R.H., & Willis, W.D. (1991). Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons. Journal of Neurophysiology, 66, 228-246.
94. Sugiura, Y., Terui, N., & Hosoa, Y. (1989). Differences in the distribution of central terminals between visceral and somatic unmyelinated primary afferent fibers. Journal of Neurophysiology, 62, 834-840.
95. Szurszewski, J.H., & King, B.F. (1989). Physiology of prevertebral ganglia in mammals with special reference to inferior mesenteric ganglion. In J. Wood (Ed.). Handbook of physiology, section G: the gastrointestinal system, vol. 1 (pp. 519-592). Bethesda: American Physiological Society.
96. Thompson, W.G. (1991). Irritable bowel syndrome. In S.F. Phillips, J.H. Pemberton, & R.G. Shorter (Eds.). The large intestine: physiology, pathophysiology and disease (pp. 593-610). New York: Raven Press.
97. Thorén, P. (1979). Role of cardiac vagal C-fibers in cardiovascular control. Reviews of Physiology, Biochemistry and Pharmacology, 86, 1-94.
98. Torebjörk, H.E., Lundberg, L.E.R., & LaMotte, R.H. (1992). Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans. Journal of Physiology, 448, 765-780.
99. Vallbo, A.B., Olsson, K.A., Westberg, K.-G., & Clark, F.J. (1984). Microstimulation of single tactile afferents from the human hand: sensory attributes related to unit type and properties of receptive fields. Brain, 107, 727-749.
100. Wall, P.D. (1978). The gate control theory of pain mechanisms. A re-examination and re-statement. Brain, 101, 1-18.
101. Widdicombe, J.G. (1986). Sensory innervation of the lungs and airways. In F. Cervero, & J.F.B. Morrison (Eds.). Visceral sensation. Progress in Brain Research, 67, 49-64.
102. Willis, W.D., & Coggeshall, R.E. (1991). Sensory mechanisms of the spinal cord. New York, London, Plenum Press.