Recombinant activated factor VII in an unselected series of cases with upper gastrointestinal bleeding

Thrombosis Research

Volumn 118, Issue 5, 2006, Pages 595-601

  Vilstrup, Hendrik ^a   Markiewicz, Malgorzata ^b   Biesma, Douwe ^c   Brozovic, Vesna Vegar ^d   Laminoga, Nikolay ^e   Malik, Marcin ^f   Milanov, Stoyan ^g   Patch, David ^h   Platikanov, Vilian ⁱ  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

^c ST ANTONIUS HOSPITAL   (Netherlands)

^d KBC Zagreb   (Croatia)

^e Archangelsk Oblastoy Clinical Children's Hospital   (Russian Federation)

^f 109 Military Hospital   (Poland)

^g Multiprofile Hospital for Active Treatment and Emergency Medicine 'Pirogov'   (Bulgaria)

^h ROYAL FREE HOSPITAL   (United Kingdom)

ⁱ University Hospital   (Bulgaria)

Author keywords

Hemostasis; Liver failure; rFVIIa; Upper gastrointestinal bleeding

Indexed keywords

ANTIFIBRINOLYTIC AGENT; APROTININ; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TRANEXAMIC ACID;

ABSENCE OF SIDE EFFECTS; ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD CLOTTING; BLOOD TRANSFUSION; CAUSE OF DEATH; CLINICAL ARTICLE; CLINICAL TRIAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEATH; DIGESTIVE SYSTEM INJURY; DISEASE ASSOCIATION; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TREATMENT FAILURE; DUODENUM ULCER; FATALITY; FEMALE; HEMATOLOGICAL PARAMETERS; HEMORRHAGIC GASTRITIS; HUMAN; LIVER DISEASE; MALE; PANCREATITIS; PATIENT SELECTION; PEPTIC ULCER; PRIORITY JOURNAL; SCHOOL CHILD; SEPSIS; THROMBOEMBOLISM; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE; UPPER GASTROINTESTINAL BLEEDING;

ADOLESCENT; ADULT; CHILD; FACTOR VII; FACTOR VIIA; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; RECOMBINANT PROTEINS; TREATMENT OUTCOME; UPPER GASTROINTESTINAL TRACT;

EID: 33748763572     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2005.10.008     Document Type: Article

References (34)

1. British Society of Gastroenterology Endoscopy Committee. Non-variceal upper gastrointestinal haemorrhage: guidelines. Gut 52 SIV (2002) iv1-iv6
2. Huang C.S., and Lichtenstein D.R. Nonvariceal upper gastrointestinal bleeding. Gastroenterol Clin N Am 32 (2003) 1053-1078
3. Yavorski R.T., Wong R.K., Maydonovitch C., Battin L.S., Furnia A., and Amundson D.E. Analysis of 3294 cases of upper gastrointestinal bleeding in military medical facilities. Am J Gastroenterol 90 (1995) 568-573
4. Rockall T.A., Logan R.F.A., Devlin H.B., and Northfield T.C. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. Steering Committee and members of the National Audit of Acute Upper Gastrointestinal Haemorrhage. BMJ 311 (1995) 222-226
5. Conrad S.A. Acute upper gastrointestinal bleeding in critically ill patients: causes and treatment modalities. Crit Care Med 30 S6 (2002) S365-S368
6. Arora N.K., Ganguly S., Mathur P., Ahuja A., and Patwari A. Upper gastrointestinal bleeding: etiology and management. Indian J Pediatr 69 (2002) 155-168
7. Dallal H.J., and Palmer K.R. ABC of the upper gastrointestinal tract: upper gastrointestinal haemorrhage. BMJ 323 (2001) 1115-1117
8. Banares R., Albillos A., Rincon D., Alonso S., Gonzalez M., Ruiz-del-Arbol L., et al. Endoscopic treatment versus endoscopic plus pharmacological treatment for acute variceal bleeding: a meta-analysis. Hepatology 35 (2002) 609-615
9. Hedner U. NovoSeven® as a universal haemostatic agent. Blood Coagul Fibrinolysis 11 (2000) 107-111
10. Bernstein D.E., Jeffers L., Erhardtsen E., Reddy K.R., Glazer S., Squiban P., et al. Recombinant factor VIIa corrects prothrombin time in cirrhotic patients: a preliminary study. Gastroenterology 113 (1997) 1930-1937
11. Kenet G., Walden R., Eldad A., and Martinowitz U. Treatment of traumatic bleeding with recombinant factor VIIa. Lancet 354 (1999) 1879
12. Chuansumrit A., Chantarojanasiri T., Isarangkura P., Teeraratkul S., Hongeng S., and Hathirat P. Recombinant activated factor VII in children with acute bleeding resulting from liver failure and disseminated intravascular coagulation. Blood Coagul Fibrinolysis 11 S1 (2000) S101-S105
13. Friederich P.W., Henny C.P., Messelink E.J., Geerdink M.G., Keller T., Kurth K.H., et al. Effect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trial. Lancet 361 (2003) 201-205
14. Holcomb J.B., Neville H.L., Fischer C.F., and Hoots K. Use of recombinant FVIIa for intraperitoneal coagulopathic bleeding in a septic patient. Curr Surg 60 (2003) 423-427
15. Kristensen J., Killander A., Hippe E., Helleberg C., Ellegard J., Holm M., et al. Clinical experience with recombinant factor VIIa in patients with thrombocytopenia. Haemostasis 26 S1 (1996) 159-164
16. O'Neill P.A., Bluth M., Gloster E.S., Wali D., Priovolos S., DiMaio T.M., et al. Successful use of recombinant activated factor VII for trauma-associated hemorrhage in a patient without preexisting coagulopathy. J Trauma 52 (2002) 400-405
17. Park P., Fewel M.E., Garton H.J., Thompson B.G., and Hoff J.T. Recombinant activated factor VII for the rapid correction of coagulopathy in nonhemophilic neurosurgical patients. Neurosurgery 53 (2003) 34-39
18. Tobias J.D., Berkenbosch J.W., and Russo P. Recombinant factor VIIa to treat bleeding after cardiac surgery in an infant. Pediatr Crit Care Med 4 (2003) 49-51
19. Ejlersen E., Melsen T., Ingerslev J., Andreasen R.B., and Vilstrup H. Recombinant activated factor VII (rFVIIa) acutely normalizes prothrombin time in patients with cirrhosis during bleeding from oesophageal varices. Scand J Gastroenterol 36 (2001) 1081-1085
20. Kessler C. Haemostasis.com: clinical experiences in the investigational use of rFVIIa in the management of severe haemorrhage. Br J Haematol 127 (2004) 230-239
21. Ikuta S., Miki C., Hatada T., Inoue Y., Araki T., Tanaka K., et al. Allogeneic blood transfusion is an independent risk factor for infective complications after less invasive gastrointestinal surgery. Am J Surg 185 (2003) 188-193
22. Mercuriali F., and Inghilleri G. Transfusion risks and limitations. Minerva Anestesiol 65 (1999) 286-292
23. Murphy P., Heal J.M., and Blumberg N. Infection or suspected infection after hip replacement surgery with autologous or homologous blood transfusions. Transfusion 31 (1991) 212-217
24. Vamvakas E.C., and Carven J.H. Exposure to allogeneic plasma and risk of postoperative pneumonia and/or wound infection in coronary artery bypass graft surgery. Transfusion 42 (2002) 107-113
25. Udvardy M., Telek B., Mezey G., Batar P., and Altorjay I. Successful control of massive coumarol-induced acute upper gastrointestinal bleeding and correction of prothrombin time by recombinant active factor VII (Eptacog-alpha, NovoSeven) in a patient with a prosthetic aortic valve and two malignancies (chronic lymphoid leukaemia and lung cancer). Blood Coagul Fibrinolysis 15 (2004) 265-267
26. Bosch J., Thabut D., Bendtsen F., D'Amico G., Albillos A., Gonzalez Abraldes J., et al. Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: a randomized, double-blind trial. Gastroenterology 127 (2004) 1123-1130
27. Roberts H.R., Monroe III D.M., and Hoffman M. Safety profile of recombinant factor VIIa. Semin Hematol 41 S1 (2004) 101-108
28. Monroe D.M., Hoffman M., Oliver J.A., and Roberts H.R. Platelet activity of high-dose factor VIIa is independent of tissue factor. Br J Haematol 99 (1997) 542-547
29. NovoSeven Prescribing Information. Novo Nordisk Pharmaceuticals Inc; 2003.
30. Afessa B., and Kubilis P.S. Upper gastrointestinal bleeding in patients with hepatic cirrhosis: clinical course and mortality prediction. Am J Gastroenterol 95 (2000) 484-489
31. Corley D.A., Stefan A.M., Wolf M., Cook E.F., and Lee T.H. Early indicators of prognosis in upper gastrointestinal hemorrhage. Am J Gastroenterol 93 (1998) 336-340
32. D'Amico G., De Franchis R., and Cooperative Study Group. Upper digestive bleeding in cirrhosis, Post-therapeutic outcome and prognostic indicators. Hepatology 38 (2003) 599-612
33. Ruiz D., Farran L., Ramos E., Biondo S., Moreno P., Bettonica C., et al. Results of the management of upper gastrointestinal bleeding from gastroesophageal varices. Rev Esp Enferm Dig 93 (2001) 433-444
34. Dejgaard A. Update on Novo Nordisk's clinical trial programme on NovoSeven®. Blood Coagul Fibrinolysis 14 S1 (2003) S39-S41