Recombinant factor VIIa to treat bleeding after cardiac surgery in an infant

Pediatric Critical Care Medicine

Volumn 4, Issue 1, 2003, Pages 49-51

  Tobias, Joseph D ^a,b   Berkenbosch, John W ^b   Russo, Pierantonio ^b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Atrial septal defect; Cardiopulmonary bypass; Fresh frozen plasma; Partial thromboplastin time; Prothrombin time

Indexed keywords

BLOOD CLOTTING FACTOR 7A;

ARTICLE; BLEEDING; CARDIOPULMONARY BYPASS; CASE REPORT; CONGENITAL HEART MALFORMATION; FEMALE; HEART SEPTUM DEFECT; HUMAN; INFANT; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME;

CARDIOPULMONARY BYPASS; FACTOR VIIA; FEMALE; HEART DEFECTS, CONGENITAL; HEART SEPTAL DEFECTS, ATRIAL; HEMORRHAGE; HUMANS; INFANT; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME;

EID: 85047687039     PISSN: 15297535     EISSN: 19473893     Source Type: Journal    
DOI: 10.1097/00130478-200301000-00009     Document Type: Article

References (14)

1. Cote CJ, Drop LJ, Hoaglin DC, et al: Ionized hypocalcemia after fresh frozen plasma administration to thermally injured children. Anesth Analg 1988; 67:152-160
2. Hedner U, Schulman S, Alberta KA, et al: Successful use of rFVIIa in a patient with severe hemophilia A subjected to synovectomy. Lancet 1988; 342:1193
3. Hedner U: Recombinant coagulation factor VIIa: From the concept to clinical application in hemophilia treatment in 2000. Semin Thromb Hemost 2000; 26:363-366
4. Tobias JD: Synthetic factor VIIa to treat dilutional coagulopathy during posterior spinal fusion in two children. Anesthesiology 2002; 96:1522-1525
5. Chuansumrit A, Chantarojanasiri T, Isarangkura P, et al: Recombinant activated factor VII in children with acute bleeding resulting from liver failure and disseminated intravascular coagulation. Blood Coagul Fibrinolysis 2000; 11(Suppl 1):S101-S105
6. Chuansumrit A, Treepongkaruna S, Phuapradit P, et al: Combined fresh frozen plasma with recombinant factor VIIa in restoring hemostasis for invasive procedures in children with liver diseases. Thromb Hemost 2001; 85:748-749
7. Kalicinski P, Kaminski A, Drewniak T, et al: Quick correction of hemostasis in two patients with fulminant liver failure undergoing liver transplantation by recombinant activated factor VII. Transplant Proc 1999; 31: 378-379
8. Hendriks HGD, van der Maaten JMA, de Wold J, et al: An effective treatment of severe intractable bleeding after valve repair by one single dose of activated recombinant factor VII. Anesth Analg 2001; 93:287-289
9. Al Douri M, Shafi T, Al Khudairi D, et al: Effect of the administration of recombinant activated factor VII (rFVIIa; NovoSeven) in the management of severe uncontrolled bleeding in patients undergoing heart valve replacement surgery. Blood Coagul Fibrinolysis 2000; 11(Suppl):S121-127
10. Tobias JD, Berkenbosch JW, Muruve NA, et al: Correction of coagulopathy using synthetic factor VII prior to removal of intraaortic balloon pump. J Cardiothorac Vasc Anesth In Press
11. Hashim SW, Kay HR, Hammond GL, et al: Noncardiogenic pulmonary edema after cardiopulmonary bypass: An anaphylactoid reaction to fresh frozen plasma. Am J Surg 1984; 147:560-564
12. Poon MC, Demers C, Jobin F, et al: Recombinant factor VIIa is effective for bleeding and surgery in patients with Glanzmann thrombasthenia. Blood 1999; 94:3951-3953
13. Kristensen J, Killander A, Hippe E, et al: Clinical experience with recombinant factor VIIa in patients with thrombocytopenia. Haemostasis 1996; 26(Suppl 1):159-164
14. Levy JH: Pharmacologic preservation of the hemostasis system during cardiac surgery. Ann Thorac Surg 2001; 72: S1814-S1820