Association study of promoter polymorphisms within the NOS3 gene and allergic diseases

International Archives of Allergy and Immunology

Volumn 141, Issue 2, 2006, Pages 103-109

  Holla, Lydie Izakovicova ^a   Stejskalova, Andrea ^a   Znojil, Vladimír ^a   Vasku, Anna ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Asthma; Endothelial nitric oxide synthase; eNOS; Gender differences; Nitric oxide; NOS3; Polymorphism

Indexed keywords

NITRIC OXIDE;

ADOLESCENT; ADULT; ALLERGIC DISEASE; ARTICLE; ASTHMA; CAUCASIAN; CONTROLLED STUDY; CZECH REPUBLIC; FEMALE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STATISTICAL DISTRIBUTION; STATISTICAL SIGNIFICANCE;

ADULT; ASTHMA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; HYPERSENSITIVITY; MALE; NITRIC OXIDE SYNTHASE TYPE III; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); SEX FACTORS;

EID: 33748760064     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000094536     Document Type: Article

References (41)

1. Di Maria GU, Spicuzza L, Mistretta A, Mazzarella G: Role of endogenous nitric oxide in asthma. Allergy 2000;55:31-35.
2. Nathan C, Xie QW: Nitric oxide synthases: roles, tolls and controls. Cell 1994;78:915-918.
3. Watkins DN, Peroni DJ, Baschon KA, Garlepp MJ, Thompson PJ: Expression and activity of nitric oxide synthases in human airway epithelium. Am J Respir Cell Mol Biol 1997;16:629-639.
4. Lane C, Knight D, Burgess S, Franklin P, Horak F, Legg J, Moeller A, Stick S: Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath. Thorax 2004;59:757-760.
5. Sippel JM, Holden WE, Tilles SA, O'Hollaren M, Cook J, Thukkani N, Priest J, Nelson B, Osborne ML: Exhaled nitric oxide levels correlate with measures of disease control in asthma. J Allergy Clin Immunol 2000;106:645-650.
6. Cardinale F, de Benedictis FM, Muggeo V, Giordano P, Loffredo MS, Iacoviello G, Armenio L: Exhaled nitric oxide, total serum IgE and allergic sensitization in childhood asthma and allergic rhinitis. Pediatr Allergy Immunol 2005;16:236-242.
7. Hamid Q, Springall DR, Riveros-Moreno V, Chanez P, Howarth P, Redington A, Bousquet J, Godard P, Holgate S, Polak JM: Induction of nitric oxide synthase in asthma. Lancet 1993;342:1510-1513.
8. Grasemann H, Storm van's Gravesande K, Buscher R, Drazen JM, Ratjen F: Effects of sex and of gene variants in constitutive nitric oxide synthases on exhaled nitric oxide. Am J Respir Crit Care Med 2003;167:1113-1116.
9. Storm van's Gravesande K, Wechsler ME, Grasemann H, Silverman ES, Le L, Palmer LJ, Drazen JM: Association of a missense mutation in the NOS3 gene with exhaled nitric oxide levels. Am J Respir Crit Care Med 2003;168:228-231.
10. Thomas PS, Bruce C, Birkhead A, Wang XL: Effect of ecNOS polymorphisms and coronary artery disease upon exhaled nitric oxide. J Mol Med 2002;80:181-186.
11. Barnes PJ, Liew FY: Nitric oxide and asthmatic inflammation. Immunol Today 1995;16:128-130.
12. Trifilieff A, Fujitani Y, Mentz F, Dugas B, Fuentes M, Bertrand C: Inducible nitric oxide synthase inhibitors suppress airway inflammation in mice through down-regulation of chemokine expression. J Immunol 2000;165:1526-1533.
13. Hall AV, Antoniou H, Wang Y, Cheung AH, Arbus AM, Olson SL, Lu WC, Kau CL, Marsden PA: Structural organization of the human neuronal nitric oxide synthase gene (NOS1). J Biol Chem 1994;269:33082-33090.
14. Chartrain NA, Geller DA, Koty PP, Sitrin NF, Nussler AK, Hoffman EP, Billiar TR, Hutchinson NI, Mudgett JS: Molecular cloning, structure, and chromosomal localization of the human inducible nitric oxide synthase gene. J Biol Chem 1994;269:6765-6772.
15. Marsden PA, Heng HH, Scherer SW, Stewart RJ, Hall AV, Shi XM, Tsui LC, Schappert KT: Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem 1993;268:17478-17488.
16. Busse R, Fleming I: Regulation and functional consequences of endothelial nitric oxide formation. Ann Med 1995;27:331-340.
17. Novoradovsky A, Brantly ML, Waclawiw MA, Chaudhary PP, Ihara H, Qi L, Eissa NT, Barnes PM, Gabriele KM, Ehrmantraut ME, Rogliani P, Moss J: Endothelial nitric oxide synthase as a potential susceptibility gene in the pathogenesis of emphysema in α1-antitrypsin deficiency. Am J Respir Cell Mol Biol 1999;20:441-447.
18. Nakayama M, Yasue H, Yoshimura M, Shimasaki Y, Kugiyama K, Ogawa H, Motoyama T, Saito Y, Ogawa Y, Miamoto Y, Nakao K: T-786→C mutation in the 5′-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation 1999;99:2864-2870.
19. Miyamoto Y, Saito Y, Nakayama M, Shimasaki Y, Yoshimura T, Yoshimura M, Harada M, Kajiyama N, Kishimoto I, Kuwahara K, Hino J, Ogawa E, Hamanaka I, Kamitani S, Takahashi N, Kawakami R, Kangawa K, Yasue H, Nakao K: Replication protein A1 reduces transcription of the endothelial nitric oxide synthase gene containing a -786T→C mutation associated with coronary spastic angina. Hum Mol Genet 2000;9:2629-2637.
20. Holla LI, Buckova D, Kuhrova V, Stejskalova A, Francova H, Znojil V, Vacha J: Prevalence of endothelial nitric oxide synthase gene polymorphism in patients with atopic asthma. Clin Exp Allergy 2002;32:1193-1198.
21. Forte P, Kneale BJ, Milne E, Chowienczyk PJ, Johnston A, Benjamin N, Ritter JM: Evidence for a difference in nitric oxide biosynthesis between healthy women and men. Hypertension 1998;32:730-734.
22. Tsang KW, Ip SK, Leung R, Tipoe GL, Chan SL, Shum IH, Ip MS, Yan C, Fung PC, Chan-Yeung M, Lam W: Exhaled nitric oxide: the effects of age, gender and body size. Lung 2001;179:83-91.
23. Global Strategy for Asthma Management and Prevention. Global Initiative for Asthma. NIH Publication No. 01-3659, NHLBI/ WHO 2002, Bethesda, Md., National Institutes of Health.
24. Bousquet J, Van Cauwenberge PN, Khaltaev N: Allergic rhinitis and its impact on asthma: ARIA workhop report. J Allergy Clin Immunol 2001;108:S148-S333.
25. Hanifin JM, Rajka G: Diagnostic features of atopic dermatitis. Acta Derm Venereol (Stockh) 1980;92:44-47.
26. Buckova D, Holla LI, Vasku A, Znojil V, Vacha J: Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population. J Invest Allergol Clin Immunol 2002;12:192-197.
27. Hedrick PW: Genetics of Populations. Boston, Jones & Bartlett, 1985.
28. 2+ and ecNOS activity. Am J Physiol 1999;276:H961-H969.
29. Lee YC, Cheon KT, Lee HB, Kim W, Rhee YK, Kim DS: Gene polymorphisms of endothelial nitric oxide synthase and angiotensin-converting enzyme in patients with asthma. Allergy 2000;55:959-963.
30. Gao PS, Kawada H, Kasamatsu T, Mao XQ, Roberts MH, Miyamoto Y, Yoshimura M, Saitoh Y, Yasue H, Nakao K, Adra N, Kun JF, Moro-oka S, Inoko H, Ho LP, Shirakawa T, Hopkin JM: Variants of NOS1, NOS2, and NOS3 genes in asthmatics. Biochem Biophys Res Commun 2000;267:761-763.
31. Yildiz P, Oflaz H, Cine N, Genchallac H, Erginel-Unaltuna N, Yildiz A, Yilmaz V: Endothelial dysfunction in patients with asthma: the role of polymorphisms of ACE and endothelial NOS genes. J Asthma 2004;41:159-166.
32. Yanamandra K, Boggs PB, Thurmon TF, Lewis D, Bocchini JA Jr, Dhanireddy R: Novel allele of the endothelial nitric oxide synthase gene polymorphism in Caucasian asthmatics. Biochem Biophys Res Commun 2005;335:545-549.
33. Shaul PW, North AJ, Wu LC, Wells LB, Brannon TS, Lau KS, Michel T, Margraf LR, Star RA: Endothelial nitric oxide synthase is expressed in cultured human bronchiolar epithelium. J Clin Invest 1994;94:2231-2236.
34. Feletou M, Lonchampt M, Coge F, Galizzi JP, Bassoullet C, Merial C, Robineau P, Boutin JA, Huang PL, Vanhoutte PM, Canet E: Regulation of murine airway responsiveness by endothelial nitric oxide synthase. Am J Physiol Lung Cell Mol Physiol 2001;281:L258-L267.
35. Alving K, Witzberg E, Lundberg J: Increased amount of nitric oxide in exhaled air of asthmatics. Eur Respir J 1993;6:1368-1370.
36. Ricciardolo FLM: Multiple role of nitric oxide in the airways. Thorax 2003;58:175-182.
37. Franklin PJ, Stick SM, Le Souëf PN, Ayres JG, Turner SW: Measuring exhaled nitric oxide levels in adults. Chest 2004;126:1540-1545.
38. Pijnenburg MW, Lissenberg ET, Hofhuis W, Ghiro L, Ho WC, Holland WP, de Jongste JC: Exhaled nitric oxide measurements with dynamic flow restriction in children aged 4-8 years. Eur Respir J 2002;20:919-924.
39. Lantin-Hermoso RL, Rosenfeld CR, Yuhanna IS, German Z, Chen Z, Shaul PW: Estrogen acutely stimulates nitric oxide synthase activity in fetal pulmonary artery endothelium. Am J Physiol 1997;273:L119-L126.
40. Kirsch EA, Yuhanna YS, Chen Z, German Z, Sherman TS, Shaul PW: Estrogen acutely stimulates endothelial nitric oxide synthase in H441 human airway epithelial cells. Am J Respir Cell Mol Biol 1999;20:658-666.
41. Quanjer PH: Standardized Lung Function Testing. Clin Respir Physiol 1983;19(suppl 5):1-95.