-
1
-
-
0141611923
-
Age-related changes in adrenergic signaling: Clinical and mechanistic implications
-
Schutzer WE, Mader SL. Age-related changes in adrenergic signaling: clinical and mechanistic implications. Ageing Res Rev. 2003;2:169-190.
-
(2003)
Ageing Res Rev
, vol.2
, pp. 169-190
-
-
Schutzer, W.E.1
Mader, S.L.2
-
2
-
-
0021362148
-
Beta-1 and beta-2 adrenoceptor-mediated responses in preparations of pulmonary artery and aorta from young and aged rats
-
O'Donnell S, Wanstall J. Beta-1 and beta-2 adrenoceptor-mediated responses in preparations of pulmonary artery and aorta from young and aged rats. J Pharmacol Exp Ther. 1984;228:733-738.
-
(1984)
J Pharmacol Exp Ther
, vol.228
, pp. 733-738
-
-
O'Donnell, S.1
Wanstall, J.2
-
3
-
-
0028043535
-
Signal transduction and regulation in smooth muscle
-
Somlyo AP, Somlyo AV. Signal transduction and regulation in smooth muscle. Nature. 1994;372:231-236.
-
(1994)
Nature
, vol.372
, pp. 231-236
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
4
-
-
0025788724
-
Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase
-
Roth N, Campbell P, Caron M, Lefkowitz R, Lohse M. Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1991;88:6201-6204.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 6201-6204
-
-
Roth, N.1
Campbell, P.2
Caron, M.3
Lefkowitz, R.4
Lohse, M.5
-
5
-
-
0022871765
-
Beta-adrenergic agonist-mediated desensitization in senescent rats
-
Scarpace PJ, Abrass IB. Beta-adrenergic agonist-mediated desensitization in senescent rats. Mech Ageing Dev. 1986;35:255-264.
-
(1986)
Mech Ageing Dev
, vol.35
, pp. 255-264
-
-
Scarpace, P.J.1
Abrass, I.B.2
-
6
-
-
0028986867
-
β-adrenoceptor-Gαs coupling decreases with age in rat aorta
-
Gurdal H, Friedman E, Johnson M. β-adrenoceptor-Gαs coupling decreases with age in rat aorta. Mol Pharmacol. 1995;47:772-778.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 772-778
-
-
Gurdal, H.1
Friedman, E.2
Johnson, M.3
-
7
-
-
0030613761
-
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
-
Daaka Y, Luttrell DK, Lefkowitz RJ. Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A. Nature. 1997;390:88-91.
-
(1997)
Nature
, vol.390
, pp. 88-91
-
-
Daaka, Y.1
Luttrell, D.K.2
Lefkowitz, R.J.3
-
8
-
-
17144439929
-
Beta-adrenergic signaling in the heart: Dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins
-
Xiao RP. Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins. Sci STKE. 2001;2001:RE15.
-
(2001)
Sci STKE
, vol.2001
-
-
Xiao, R.P.1
-
9
-
-
0036839745
-
Dancing with different partners: Protein kinase a phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity
-
Lefkowitz RJ, Pierce KL, Luttrell LM. Dancing with different partners: protein kinase A phosphorylation of seven membrane-spanning receptors regulates their G protein-coupling specificity. Mol Pharmacol. 2002;62:971-974.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 971-974
-
-
Lefkowitz, R.J.1
Pierce, K.L.2
Luttrell, L.M.3
-
10
-
-
0034093205
-
Functional receptor coupling to Gi is a mechanism of agonist-promoted desensitization of the β2-adrenergic receptor
-
Tepe NM, Liggett SB. Functional receptor coupling to Gi is a mechanism of agonist-promoted desensitization of the β2-adrenergic receptor. J Recept Signal Transduct Res. 2000;20:75-85.
-
(2000)
J Recept Signal Transduct Res
, vol.20
, pp. 75-85
-
-
Tepe, N.M.1
Liggett, S.B.2
-
11
-
-
0024409631
-
Role of cyclic AMP-dependent protein kinase in the diminished beta-adrenergic responsiveness of vascular smooth muscle with increasing age
-
Deisher TA, Mankani S, Hoffman BB. Role of cyclic AMP-dependent protein kinase in the diminished beta-adrenergic responsiveness of vascular smooth muscle with increasing age. J Pharmacol Exp Ther. 1989;249:812-819.
-
(1989)
J Pharmacol Exp Ther
, vol.249
, pp. 812-819
-
-
Deisher, T.A.1
Mankani, S.2
Hoffman, B.B.3
-
16
-
-
0032842281
-
Impaired isoproterenol-induced hyperpolarization in isolated mesenteric arteries of aged rats
-
Fujii K, Onaka U, Goto K, Abe I, Fujishima M. Impaired isoproterenol-induced hyperpolarization in isolated mesenteric arteries of aged rats. Hypertension. 1999;34:222-228.
-
(1999)
Hypertension
, vol.34
, pp. 222-228
-
-
Fujii, K.1
Onaka, U.2
Goto, K.3
Abe, I.4
Fujishima, M.5
-
17
-
-
0026007020
-
Pertussis toxin reduces endothelium-dependent and independent responses to alpha-2- adrenergic stimulation in systemic canine arteries and veins
-
Miller VM, Flavahan NA, Vanhoutte PM. Pertussis toxin reduces endothelium-dependent and independent responses to alpha-2- adrenergic stimulation in systemic canine arteries and veins. J Pharmacol Exp Ther. 1991;257:290-293.
-
(1991)
J Pharmacol Exp Ther
, vol.257
, pp. 290-293
-
-
Miller, V.M.1
Flavahan, N.A.2
Vanhoutte, P.M.3
-
18
-
-
0037024203
-
Vasodilator signals from the ischemic myocardium are transduced to the coronary vascular wall by pertussis toxin-sensitive G proteins: A new experimental method for the analysis of the interaction between the myocardium and coronary vessels
-
Sato K, Komaru T, Shioiri H, et al. Vasodilator signals from the ischemic myocardium are transduced to the coronary vascular wall by pertussis toxin-sensitive G proteins: a new experimental method for the analysis of the interaction between the myocardium and coronary vessels. J Am Coll Cardiol. 2002;39:1859-1865.
-
(2002)
J Am Coll Cardiol
, vol.39
, pp. 1859-1865
-
-
Sato, K.1
Komaru, T.2
Shioiri, H.3
-
19
-
-
0035865433
-
Lack of involvement of pertussis toxin-sensitive G-proteins in norepinephrine-induced vasoconstriction of rat aorta smooth muscle
-
Petitcolin MA, Vandeputte C, Spitzbarth-Regrigny E, Bueb JL, Capdeville-Atkinson C, Tschirhart E. Lack of involvement of pertussis toxin-sensitive G-proteins in norepinephrine-induced vasoconstriction of rat aorta smooth muscle. Biochem Pharmacol. 2001;61:485-491.
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 485-491
-
-
Petitcolin, M.A.1
Vandeputte, C.2
Spitzbarth-Regrigny, E.3
Bueb, J.L.4
Capdeville-Atkinson, C.5
Tschirhart, E.6
-
20
-
-
0022450140
-
Effects of prolonged isoproterenol infusion on cardiac and vascular responses to adrenoceptor agonists
-
Hayes JS, Wyss VL, Schenck KS, Cohen ML. Effects of prolonged isoproterenol infusion on cardiac and vascular responses to adrenoceptor agonists. J Pharmacol Exp Ther. 1986;237:757-763.
-
(1986)
J Pharmacol Exp Ther
, vol.237
, pp. 757-763
-
-
Hayes, J.S.1
Wyss, V.L.2
Schenck, K.S.3
Cohen, M.L.4
-
21
-
-
0025122884
-
Modulation of adrenoceptor-mediated cardiovascular effects by short-term in vivo infusion of isoproterenol in rats
-
Vleeming W, van Rooij HH, Wemer J, Porsius AJ. Modulation of adrenoceptor-mediated cardiovascular effects by short-term in vivo infusion of isoproterenol in rats. J Cardiovasc Pharmacol. 1990;16:584-593.
-
(1990)
J Cardiovasc Pharmacol
, vol.16
, pp. 584-593
-
-
Vleeming, W.1
Van Rooij, H.H.2
Wemer, J.3
Porsius, A.J.4
-
22
-
-
0015349948
-
The prevention of isoproterenol desensitization and isoproterenol reversal
-
Fleisch JH, Titus E. The prevention of isoproterenol desensitization and isoproterenol reversal. J Pharmacol Exp Ther. 1972;181:425-433.
-
(1972)
J Pharmacol Exp Ther
, vol.181
, pp. 425-433
-
-
Fleisch, J.H.1
Titus, E.2
-
23
-
-
0032810272
-
Relative resistance of functional beta2-adrenoceptor-mediated smooth muscle responses to in vitro desensitization
-
Martin SW, Broadley KJ. Relative resistance of functional beta2-adrenoceptor-mediated smooth muscle responses to in vitro desensitization. Can J Physiol Pharmacol. 1999;77:156-165.
-
(1999)
Can J Physiol Pharmacol
, vol.77
, pp. 156-165
-
-
Martin, S.W.1
Broadley, K.J.2
-
24
-
-
0033804613
-
Vascular β-adrenergic receptor adenylyl cyclase system in maturation and aging
-
Gaballa MA, Eckhart AD, Koch WJ, Goldman S. Vascular β-adrenergic receptor adenylyl cyclase system in maturation and aging. J Mol Cell Cardiol. 2000;32:1745-1755.
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 1745-1755
-
-
Gaballa, M.A.1
Eckhart, A.D.2
Koch, W.J.3
Goldman, S.4
-
25
-
-
0026519047
-
Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells
-
Mader SL. Influence of animal age on the beta-adrenergic system in cultured rat aortic and mesenteric artery smooth muscle cells. J Gerontol Biol Sci. 1992;42A:B32-B36.
-
(1992)
J Gerontol Biol Sci
, vol.42
-
-
Mader, S.L.1
-
26
-
-
0023578747
-
Catecholamines and cardiovascular function in aging
-
Lakatta EG. Catecholamines and cardiovascular function in aging. Endocrinol Metab Clin North Am. 1987;16:877-891.
-
(1987)
Endocrinol Metab Clin North Am
, vol.16
, pp. 877-891
-
-
Lakatta, E.G.1
-
27
-
-
0028897692
-
Decreased stress responsivity of central and peripheral catecholaminergic systems in aged 344/N Fischer rats
-
Cizza G, Pacak K, Kvetnansky R, et al. Decreased stress responsivity of central and peripheral catecholaminergic systems in aged 344/N Fischer rats. J Clin Invest. 1995;95:1217-1224.
-
(1995)
J Clin Invest
, vol.95
, pp. 1217-1224
-
-
Cizza, G.1
Pacak, K.2
Kvetnansky, R.3
-
28
-
-
0021671190
-
Effects of 2-deoxyglucose on plasma catecholamines in adult and aged rats
-
McCarty R. Effects of 2-deoxyglucose on plasma catecholamines in adult and aged rats. Neurobiol Aging. 1984;5:285-289.
-
(1984)
Neurobiol Aging
, vol.5
, pp. 285-289
-
-
McCarty, R.1
-
29
-
-
0021895227
-
Sympathetic-adrenal medullary and cardiovascular responses to acute cold stress in adult and aged rats
-
McCarty R. Sympathetic-adrenal medullary and cardiovascular responses to acute cold stress in adult and aged rats. J Auton Nerv Syst. 1985;12:15-22.
-
(1985)
J Auton Nerv Syst
, vol.12
, pp. 15-22
-
-
McCarty, R.1
-
30
-
-
0034053764
-
Increased plasma norepinephrine response to yohimbine in elderly men
-
Petrie EC, Peskind ER, Dobie DJ, Veith RC, Raskind MA. Increased plasma norepinephrine response to yohimbine in elderly men. J Gerontol Med Sci. 2000;55A:M155-M159.
-
(2000)
J Gerontol Med Sci
, vol.55
-
-
Petrie, E.C.1
Peskind, E.R.2
Dobie, D.J.3
Veith, R.C.4
Raskind, M.A.5
-
31
-
-
0026116161
-
β-adrenergic function in aging. Basic mechanisms and clinical implications
-
Scarpace PJ, Tumer N, Mader SL. β-adrenergic function in aging. Basic mechanisms and clinical implications. Drugs Aging. 1991;1:116-129.
-
(1991)
Drugs Aging
, vol.1
, pp. 116-129
-
-
Scarpace, P.J.1
Tumer, N.2
Mader, S.L.3
-
32
-
-
0028987214
-
Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes
-
Xiao RP, Ji X, Lakatta EG. Functional coupling of the beta 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes. Mol Pharmacol. 1995;47:322-329.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 322-329
-
-
Xiao, R.P.1
Ji, X.2
Lakatta, E.G.3
-
33
-
-
0037163048
-
Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system
-
Zamah AM, Delahunty M, Luttrell LM, Lefkowitz RJ. Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system. J Biol Chem. 2002;277:31249-31256.
-
(2002)
J Biol Chem
, vol.277
, pp. 31249-31256
-
-
Zamah, A.M.1
Delahunty, M.2
Luttrell, L.M.3
Lefkowitz, R.J.4
-
35
-
-
0023036993
-
Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation
-
Tsujimoto G, Lee CH, Hoffman BB. Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation. J Pharmacol Exp Ther. 1986;239:411-415.
-
(1986)
J Pharmacol Exp Ther
, vol.239
, pp. 411-415
-
-
Tsujimoto, G.1
Lee, C.H.2
Hoffman, B.B.3
-
36
-
-
0033973793
-
Viral-mediated gene delivery of constitutively activated Gas alters vasoreactivity
-
Schutzer WE, Watts VJ, Chapman J, et al. Viral-mediated gene delivery of constitutively activated Gas alters vasoreactivity. Clin Exp Pharmacol Physiol. 2000;27:9-13.
-
(2000)
Clin Exp Pharmacol Physiol
, vol.27
, pp. 9-13
-
-
Schutzer, W.E.1
Watts, V.J.2
Chapman, J.3
-
37
-
-
0001775705
-
Age-related changes in adenylyl cyclase activity in rat aorta membranes
-
Mader SL, Alley PA. Age-related changes in adenylyl cyclase activity in rat aorta membranes. Mech Ageing Dev. 1998;101:111-118.
-
(1998)
Mech Ageing Dev
, vol.101
, pp. 111-118
-
-
Mader, S.L.1
Alley, P.A.2
-
38
-
-
0142148113
-
Probing the roles of protein kinases in G-protein-coupled receptor desensitization
-
Clark RB, Rich TC. Probing the roles of protein kinases in G-protein-coupled receptor desensitization. Mol Pharmacol. 2003;64:1015-1017.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1015-1017
-
-
Clark, R.B.1
Rich, T.C.2
-
40
-
-
0033789017
-
Localization of the sites mediating desensitization of the beta 2-adrenergic receptor by the GRK pathway
-
Seibold A, Williams B, Huang ZF, et al. Localization of the sites mediating desensitization of the beta 2-adrenergic receptor by the GRK pathway. Mol Pharmacol. 2000;58:1162-1173.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 1162-1173
-
-
Seibold, A.1
Williams, B.2
Huang, Z.F.3
-
41
-
-
17644402459
-
Transduction of receptor signals by β-arrestins
-
Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by β-arrestins. Science. 2005;308:512-517.
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
42
-
-
0035002227
-
Upregulation of G protein-linked receptor kinases with advancing age in rat aorta
-
Schutzer WE, Reed JF, Bliziotes M, Mader SL. Upregulation of G protein-linked receptor kinases with advancing age in rat aorta. Am J Physiol. 2001;280:R897-R903.
-
(2001)
Am J Physiol
, vol.280
-
-
Schutzer, W.E.1
Reed, J.F.2
Bliziotes, M.3
Mader, S.L.4
-
43
-
-
0033605584
-
Regulation of G-protein receptor kinases by caveolin
-
Carman CV, Lisanti MP, Benovic JL. Regulation of G-protein receptor kinases by caveolin. J Biol Chem. 1999;274:8858-8864.
-
(1999)
J Biol Chem
, vol.274
, pp. 8858-8864
-
-
Carman, C.V.1
Lisanti, M.P.2
Benovic, J.L.3
-
44
-
-
0033213776
-
Colocalization of β-adrenergic receptors and caveolin within the plasma membrane
-
Schwencke C, Okumura S, Yamamoto M, Geng YJ, Ishikawa Y. Colocalization of β-adrenergic receptors and caveolin within the plasma membrane. J Cell Biochem. 1999;75:64-72.
-
(1999)
J Cell Biochem
, vol.75
, pp. 64-72
-
-
Schwencke, C.1
Okumura, S.2
Yamamoto, M.3
Geng, Y.J.4
Ishikawa, Y.5
-
45
-
-
18044387220
-
Decline in caveolin-1 expression and scaffolding of G protein receptor kinase-2 with age in Fischer 344 aortic vascular smooth muscle
-
Schutzer WE, Reed JF, Mader SL. Decline in caveolin-1 expression and scaffolding of G protein receptor kinase-2 with age in Fischer 344 aortic vascular smooth muscle. Am J Physiol Heart Circ Physiol. 2005;288:H2457-H2464.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
-
-
Schutzer, W.E.1
Reed, J.F.2
Mader, S.L.3
-
46
-
-
0029765512
-
Mechanisms of orthostatic hypotension and tachycardia in patients with pheochromocytoma
-
Streeten DH, Anderson GH Jr. Mechanisms of orthostatic hypotension and tachycardia in patients with pheochromocytoma. Am J Hypertens. 1996:9:760-769.
-
(1996)
Am J Hypertens
, vol.9
, pp. 760-769
-
-
Streeten, D.H.1
Anderson Jr., G.H.2
|