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Volumn 91, Issue 9, 2006, Pages 3553-3558

Low-dose rosiglitazone exerts an antiinflammatory effect with an increase in adiponectin independently of free fatty acid fall and insulin sensitization in obese type 2 diabetics

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADIPONECTIN; AMYLOID A PROTEIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FATTY ACID; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; MATRIX METALLOPROTEINASE; METFORMIN; PLACEBO; RESISTIN; ROSIGLITAZONE; SULFONYLUREA DERIVATIVE;

EID: 33748742272     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2005-2609     Document Type: Article
Times cited : (73)

References (31)
  • 1
    • 0034915177 scopus 로고    scopus 로고
    • Insulin inhibits intranuclear nuclear factor κB and stimulates IκB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?
    • Dandona P, Aljada A, Mohanty P, Ghanim H, Hamouda W, Assian E, Ahmad S 2001 Insulin inhibits intranuclear nuclear factor κB and stimulates IκB in mononuclear cells in obese subjects: evidence for an anti-inflammatory effect? J Clin Endocrinol Metab 86:3257-3265
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3257-3265
    • Dandona, P.1    Aljada, A.2    Mohanty, P.3    Ghanim, H.4    Hamouda, W.5    Assian, E.6    Ahmad, S.7
  • 2
    • 0036964978 scopus 로고    scopus 로고
    • Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations
    • Aljada A, Ghanim H, Mohanty P, Kapur N, Dandona P 2002 Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations. J Clin Endocrinol Metab 87:1419-1422
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1419-1422
    • Aljada, A.1    Ghanim, H.2    Mohanty, P.3    Kapur, N.4    Dandona, P.5
  • 3
    • 0033818040 scopus 로고    scopus 로고
    • Troglitazone reduces reactive oxygen species generation by leukocytes and lipid peroxidation and improves flow-mediated vasodilatation in obese subjects
    • Garg R, Kumbkarni Y, Aljada A, Mohanty P, Ghanim H, Hamouda W, Dandona P 2000 Troglitazone reduces reactive oxygen species generation by leukocytes and lipid peroxidation and improves flow-mediated vasodilatation in obese subjects. Hypertension 36:430-435
    • (2000) Hypertension , vol.36 , pp. 430-435
    • Garg, R.1    Kumbkarni, Y.2    Aljada, A.3    Mohanty, P.4    Ghanim, H.5    Hamouda, W.6    Dandona, P.7
  • 4
    • 0035045084 scopus 로고    scopus 로고
    • Suppression of nuclear factor-κB and stimulation of inhibitor κB by troglitazone: Evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the obese
    • Ghanim H, Garg R, Aljada A, Mohanty P, Kumbkarni Y, Assian E, Hamouda W, Dandona P 2001 Suppression of nuclear factor-κB and stimulation of inhibitor κB by troglitazone: evidence for an anti-inflammatory effect and a potential antiatherosclerotic effect in the obese. J Clin Endocrinol Metab 86:1306-1312
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1306-1312
    • Ghanim, H.1    Garg, R.2    Aljada, A.3    Mohanty, P.4    Kumbkarni, Y.5    Assian, E.6    Hamouda, W.7    Dandona, P.8
  • 5
    • 0034742613 scopus 로고    scopus 로고
    • Nuclear factor-κB suppressive and inhibitor-κB stimulatory effects of troglitazone in obese patients with type 2 diabetes: Evidence of an antiinflammatory action?
    • Aljada A, Garg R, Ghanim H, Mohanty P, Hamouda W, Assian E, Dandona P 2001 Nuclear factor-κB suppressive and inhibitor-κB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action? J Clin Endocrinol Metab 86:3250-3256
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 3250-3256
    • Aljada, A.1    Garg, R.2    Ghanim, H.3    Mohanty, P.4    Hamouda, W.5    Assian, E.6    Dandona, P.7
  • 6
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • Haffner SM, Greenberg AS, Weston WM, Chen H, Williams K, Freed MI 2002 Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation 106:679-684
    • (2002) Circulation , vol.106 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3    Chen, H.4    Williams, K.5    Freed, M.I.6
  • 8
    • 33645567880 scopus 로고    scopus 로고
    • Anti-inflammatory effects of short-term pioglitazone therapy in men with advanced diabetic nephropathy
    • Agarwal R 2005 Anti-inflammatory effects of short-term pioglitazone therapy in men with advanced diabetic nephropathy. Am J Physiol Renal Physiol 290:F600-F605
    • (2005) Am J Physiol Renal Physiol , vol.290
    • Agarwal, R.1
  • 9
    • 20644453108 scopus 로고    scopus 로고
    • Metabolic effects of pioglitazone in combination with insulin in patients with type 2 diabetes mellitus whose disease is not adequately controlled with insulin therapy: Results of a six-month, randomized, double-blind, prospective, multicenter, parallel-group study
    • Mattoo V, Eckland D, Widel M, Duran S, Fajardo C, Strand J, Knight D, Grossman L, Oakley D, Tan M 2005 Metabolic effects of pioglitazone in combination with insulin in patients with type 2 diabetes mellitus whose disease is not adequately controlled with insulin therapy: results of a six-month, randomized, double-blind, prospective, multicenter, parallel-group study. Clin Ther 27:554-567
    • (2005) Clin Ther , vol.27 , pp. 554-567
    • Mattoo, V.1    Eckland, D.2    Widel, M.3    Duran, S.4    Fajardo, C.5    Strand, J.6    Knight, D.7    Grossman, L.8    Oakley, D.9    Tan, M.10
  • 10
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
    • Ricote M, Li AC, Willson TM, Kelly CJ, Glass CK 1998 The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation. Nature 391:79-82
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 11
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation
    • Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM 2001 PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 7:48-52
    • (2001) Nat Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 13
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, Olefsky JM 2002 The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51:2968-2974
    • (2002) Diabetes , vol.51 , pp. 2968-2974
    • Yu, J.G.1    Javorschi, S.2    Hevener, A.L.3    Kruszynska, Y.T.4    Norman, R.A.5    Sinha, M.6    Olefsky, J.M.7
  • 14
    • 0036481709 scopus 로고    scopus 로고
    • Synthetic peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients
    • Yang WS, Jeng CY, Wu TJ, Tanaka S, Funahashi T, Matsuzawa Y, Wang JP, Chen CL, Tai TY, Chuang LM 2002 Synthetic peroxisome proliferator-activated receptor-γ agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care 25:376-380
    • (2002) Diabetes Care , vol.25 , pp. 376-380
    • Yang, W.S.1    Jeng, C.Y.2    Wu, T.J.3    Tanaka, S.4    Funahashi, T.5    Matsuzawa, Y.6    Wang, J.P.7    Chen, C.L.8    Tai, T.Y.9    Chuang, L.M.10
  • 19
    • 0021858978 scopus 로고
    • Prognostic importance of the white blood cell count for coronary, cancer, and all-cause mortality
    • Grimm Jr RH, Neaton JD, Ludwig W 1985 Prognostic importance of the white blood cell count for coronary, cancer, and all-cause mortality. JAMA 254:1932-1937
    • (1985) JAMA , vol.254 , pp. 1932-1937
    • Grimm Jr., R.H.1    Neaton, J.D.2    Ludwig, W.3
  • 20
    • 0026771160 scopus 로고
    • The white blood cell count and risk for coronary heart disease
    • Ensrud K, Grimm Jr RH 1992 The white blood cell count and risk for coronary heart disease. Am Heart J 124:207-213
    • (1992) Am Heart J , vol.124 , pp. 207-213
    • Ensrud, K.1    Grimm Jr., R.H.2
  • 21
    • 0026502395 scopus 로고
    • White blood cell count and cardiovascular disease. Insights from the Framingham Study
    • Kannel WB, Anderson K, Wilson PW 1992 White blood cell count and cardiovascular disease. Insights from the Framingham Study. JAMA 267:1253-1256
    • (1992) JAMA , vol.267 , pp. 1253-1256
    • Kannel, W.B.1    Anderson, K.2    Wilson, P.W.3
  • 22
    • 0032923669 scopus 로고    scopus 로고
    • C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992
    • Koenig W, Sund M, Frohlich M, Fischer HG, Lowel H, Doring A, Hutchinson WL, Pepys MB 1999 C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992. Circulation 99:237-242
    • (1999) Circulation , vol.99 , pp. 237-242
    • Koenig, W.1    Sund, M.2    Frohlich, M.3    Fischer, H.G.4    Lowel, H.5    Doring, A.6    Hutchinson, W.L.7    Pepys, M.B.8
  • 24
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross R 1999 Atherosclerosis - an inflammatory disease. N Engl J Med 340:115-126
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 25
    • 0034074887 scopus 로고    scopus 로고
    • Atherosclerotic arterial remodeling and the localization of macrophages and matrix metalloproteases 1, 2 and 9 in the human coronary artery
    • Pasterkamp G, Schoneveld AH, Hijnen DJ, de Kleijn DP, Teepen H, van der Wal AC, Borst C 2000 Atherosclerotic arterial remodeling and the localization of macrophages and matrix metalloproteases 1, 2 and 9 in the human coronary artery. Atherosclerosis 150:245-253
    • (2000) Atherosclerosis , vol.150 , pp. 245-253
    • Pasterkamp, G.1    Schoneveld, A.H.2    Hijnen, D.J.3    De Kleijn, D.P.4    Teepen, H.5    Van Der Wal, A.C.6    Borst, C.7
  • 27
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM 1996 IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance. Science 271:665-668
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 28
    • 0036116824 scopus 로고    scopus 로고
    • Tumor necrosis factor-α inhibits insulin-induced increase in endothelial nitric oxide synthase and reduces insulin receptor content and phosphorylation in human aortic endothelial cells
    • Aljada A, Ghanim H, Assian E, Dandona P 2002 Tumor necrosis factor-α inhibits insulin-induced increase in endothelial nitric oxide synthase and reduces insulin receptor content and phosphorylation in human aortic endothelial cells. Metabolism 51:487-491
    • (2002) Metabolism , vol.51 , pp. 487-491
    • Aljada, A.1    Ghanim, H.2    Assian, E.3    Dandona, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.