Combination strategies for enhancing transdermal absorption of sumatriptan through skin

International Journal of Pharmaceutics

Volumn 323, Issue 1-2, 2006, Pages 125-130

  Femenia Font A ^a   Balaguer Fernandez C ^a   Merino, V ^b   Lopez Castellano A ^a  

^a UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Chemical enhancers; Human skin; Iontophoresis; Percutaneous absorption; Sumatriptan succinate

Indexed keywords

ALCOHOL; CHEMICAL AGENT; LAUROCAPRAM; LIMONENE; MACROGOL; SUMATRIPTAN; SUMATRIPTAN SUCCINATE;

ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG TRANSPORT; FLOW; HUMAN; HUMAN TISSUE; IONTOPHORESIS; MEDICAL RESEARCH; NONHUMAN; PRIORITY JOURNAL; SKIN ABSORPTION; SWINE; VALIDATION PROCESS;

ADJUVANTS, PHARMACEUTIC; ADMINISTRATION, CUTANEOUS; ANIMALS; AZEPINES; CYCLOHEXENES; ETHANOL; HUMANS; IONTOPHORESIS; POLYETHYLENE GLYCOLS; SEROTONIN AGONISTS; SEROTONIN RECEPTOR AGONISTS; SKIN; SKIN ABSORPTION; SUMATRIPTAN; SUS SCROFA; TERPENES;

EID: 33748701445     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.05.049     Document Type: Article

References (16)

1. Barry B.W. Dermatological Formulations: Percutaneous Absorption (1983), Marcel Dekker, New York
2. Berner B., Mazzenga G.C., Otte J.H., Steffens R.J., Juang R.H., and Ebert C.D. Ethanol: water mutually enhanced transdermal therapeutic system. II. Skin permeation of ethanol and nitroglycerin. J. Pharm. Sci. 78 (1989) 402-407
3. Delgado-Charro M.B., Rodríguez-Bayón A.M., and Guy R.H. Iontophoresis of nafarelin: effects of current density and concentration on electrotransport in vitro. J. Control Release 35 (1995) 35-40
4. Femenía-Font A., Balaguer-Fernández C., Merino V., Rodilla V., and López-Castellano A. Effect of chemical enhancers on the in vitro percutaneous absorption of sumatriptan succinate. Eur. J. Pharm. Biopharm. 61 (2005) 50-55
5. Femenía-Font A., Balaguer-Fernández C., Merino V., and López-Castellano A. Iontophoretic transdermal delivery of sumatriptan: effect of current density and ionic strength. J. Pharm. Sci. 94 (2005) 2183-2186
6. Femenía-Font A., Merino V., Rodilla V., and López-Castellano A. High-performance liquid chromatographic determination of sumatriptan after in vitro transdermal diffusion studies. J. Pharm. Biomed. Anal. 37 (2005) 621-626
7. Jhee S.S., Shiovitz T., Crawford A.W., and Cutler N.R. Pharmacokinetics and pharmacodynamics of triptan antimigraine agents: a comparative review. Clin. Pharmacokinet. 40 (2001) 189-205
8. Kalia Y.N., Naik A., Garrison J., and Guy R.H. Iontophoretic drug delivery. Adv. Drug Del. Rev. 56 (2004) 619-658
9. ® on the in vitro percutaneous penetration of compounds with different lipophilicities. Int. J. Pharm. 202 (2000) 133-140
10. Megrab N.A., Williams A.C., and Barry B.W. Oestradiol permeation across human skin, silastic and snake skin membranes: the effects of ethanol/water co-solvent systems. Int. J. Pharm. 116 (1995) 101-112
11. Nair V.B., and Panchagnula R. The effect of pretreatment with terpenes on transdermal iontophoretic delivery of arginine vasopressin. Il Fármaco 59 (2004) 575-581
12. Phipps J.B., Padmanabhan R.V., and Lattin G.A. Iontophoretic delivery of model inorganic and drug ions. J. Pharm. Sci. 78 (1989) 365-369
13. Pillai O., and Panchagnula R. Transdermal delivery of insulin from poloxamer gel: ex vivo and in vivo skin permeation studies in rat using iontophoresis and chemical enhancers. J. Control Release 89 (2003) 127-140
14. Sugibayashi K., Nakayama S., Seki T., Hosoya K., and Morimoto Y. Mechanism of skin penetration-enhancing effect by laurocapram. J. Pharm. Sci. 81 (1992) 58-64
15. Wang Y., Thakur R., Fan Q., and Michniak B. Transdermal iontophoresis: combination strategies to improve transdermal iontophoresis drug delivery. Eur. J. Pharm. Biopharm. 60 (2005) 179-191
16. Williams A.C., and Barry B.W. Penetration enhancers. Adv. Drug Del. Rev. 56 (2004) 603-618