-
1
-
-
32944463899
-
Angiogenesis
-
Folkman J. Angiogenesis. Annu. Rev. Med. 57 (2006) 1-18
-
(2006)
Annu. Rev. Med.
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
2
-
-
20144379162
-
Endogenous inhibitors of angiogenesis
-
Nyberg P., et al. Endogenous inhibitors of angiogenesis. Cancer Res. 65 (2005) 3967-3979
-
(2005)
Cancer Res.
, vol.65
, pp. 3967-3979
-
-
Nyberg, P.1
-
3
-
-
0032460226
-
Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice
-
Bole-Feysot C., et al. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr. Rev. 19 (1998) 225-268
-
(1998)
Endocr. Rev.
, vol.19
, pp. 225-268
-
-
Bole-Feysot, C.1
-
4
-
-
33646793904
-
Matrix metalloproteases from chondrocytes generate an antiangiogenic 16 kDa prolactin
-
Macotela Y., et al. Matrix metalloproteases from chondrocytes generate an antiangiogenic 16 kDa prolactin. J. Cell Sci. 119 (2006) 1790-1800
-
(2006)
J. Cell Sci.
, vol.119
, pp. 1790-1800
-
-
Macotela, Y.1
-
5
-
-
5044239177
-
Cathepsin D processes human prolactin into multiple 16K-like N-terminal fragments: study of their antiangiogenic properties and physiological relevance
-
Piwnica D., et al. Cathepsin D processes human prolactin into multiple 16K-like N-terminal fragments: study of their antiangiogenic properties and physiological relevance. Mol. Endocrinol. 18 (2004) 2522-2542
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 2522-2542
-
-
Piwnica, D.1
-
6
-
-
0020317563
-
Human growth hormone: 1974-1981
-
Li C.H. Human growth hormone: 1974-1981. Mol. Cell. Biochem. 46 (1982) 31-41
-
(1982)
Mol. Cell. Biochem.
, vol.46
, pp. 31-41
-
-
Li, C.H.1
-
7
-
-
0033573994
-
Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis
-
Struman I., et al. Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 1246-1251
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 1246-1251
-
-
Struman, I.1
-
8
-
-
0027259025
-
Proteolysis of human growth hormone by rat thyroid gland in vitro: application of electrospray mass spectrometry and N-terminal sequencing to elucidate a metabolic pathway
-
Wroblewski V.J., et al. Proteolysis of human growth hormone by rat thyroid gland in vitro: application of electrospray mass spectrometry and N-terminal sequencing to elucidate a metabolic pathway. Pharm. Res. 10 (1993) 1106-1114
-
(1993)
Pharm. Res.
, vol.10
, pp. 1106-1114
-
-
Wroblewski, V.J.1
-
9
-
-
0033304969
-
Proteolysis of human prolactin: resistance to cathepsin D and formation of a nonangiostatic, C-terminal 16K fragment by thrombin
-
Khurana S., et al. Proteolysis of human prolactin: resistance to cathepsin D and formation of a nonangiostatic, C-terminal 16K fragment by thrombin. Endocrinology 140 (1999) 4127-4132
-
(1999)
Endocrinology
, vol.140
, pp. 4127-4132
-
-
Khurana, S.1
-
10
-
-
2542568181
-
Limited proteolysis of human growth hormone at low pH: isolation, characterization, and complementation of the two biologically relevant fragments 1-44 and 45-191
-
Spolaore B., et al. Limited proteolysis of human growth hormone at low pH: isolation, characterization, and complementation of the two biologically relevant fragments 1-44 and 45-191. Biochemistry 43 (2004) 6576-6586
-
(2004)
Biochemistry
, vol.43
, pp. 6576-6586
-
-
Spolaore, B.1
-
11
-
-
0036398482
-
Kringle structures and antiangiogenesis
-
Cao Y., et al. Kringle structures and antiangiogenesis. Curr. Med. Chem. Anticancer Agents 2 (2002) 667-681
-
(2002)
Curr. Med. Chem. Anticancer Agents
, vol.2
, pp. 667-681
-
-
Cao, Y.1
-
12
-
-
4444322354
-
Do antiangiogenic protein fragments have amyloid properties?
-
Gebbink M.F., et al. Do antiangiogenic protein fragments have amyloid properties?. Blood 104 (2004) 1601-1605
-
(2004)
Blood
, vol.104
, pp. 1601-1605
-
-
Gebbink, M.F.1
-
13
-
-
0036098835
-
Roles of prolactin and related members of the prolactin/growth hormone/placental lactogen family in angiogenesis
-
Corbacho A.M., et al. Roles of prolactin and related members of the prolactin/growth hormone/placental lactogen family in angiogenesis. J. Endocrinol. 173 (2002) 219-238
-
(2002)
J. Endocrinol.
, vol.173
, pp. 219-238
-
-
Corbacho, A.M.1
-
14
-
-
0035476272
-
Expression of the antiangiogenic factor 16K hPRL in human HCT116 colon cancer cells inhibits tumor growth in Rag1(-/-) mice
-
Bentzien F., et al. Expression of the antiangiogenic factor 16K hPRL in human HCT116 colon cancer cells inhibits tumor growth in Rag1(-/-) mice. Cancer Res. 61 (2001) 7356-7362
-
(2001)
Cancer Res.
, vol.61
, pp. 7356-7362
-
-
Bentzien, F.1
-
15
-
-
0037439683
-
Antitumor activity of the 16-kDa prolactin fragment in prostate cancer
-
Kim J., et al. Antitumor activity of the 16-kDa prolactin fragment in prostate cancer. Cancer Res. 63 (2003) 386-393
-
(2003)
Cancer Res.
, vol.63
, pp. 386-393
-
-
Kim, J.1
-
16
-
-
3142615282
-
Molecular targeting of antiangiogenic factor 16K hPRL inhibits oxygen-induced retinopathy in mice
-
Pan H., et al. Molecular targeting of antiangiogenic factor 16K hPRL inhibits oxygen-induced retinopathy in mice. Invest. Ophthalmol. Vis. Sci. 45 (2004) 2413-2419
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 2413-2419
-
-
Pan, H.1
-
17
-
-
9444228336
-
16K-prolactin inhibits activation of endothelial nitric oxide synthase, intracellular calcium mobilization, and endothelium-dependent vasorelaxation
-
Gonzalez C., et al. 16K-prolactin inhibits activation of endothelial nitric oxide synthase, intracellular calcium mobilization, and endothelium-dependent vasorelaxation. Endocrinology 145 (2004) 5714-5722
-
(2004)
Endocrinology
, vol.145
, pp. 5714-5722
-
-
Gonzalez, C.1
-
18
-
-
0031730107
-
Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression
-
Lee H., et al. Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression. Endocrinology 139 (1998) 3696-3703
-
(1998)
Endocrinology
, vol.139
, pp. 3696-3703
-
-
Lee, H.1
-
19
-
-
0027236943
-
The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis
-
Clapp C., et al. The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis. Endocrinology 133 (1993) 1292-1299
-
(1993)
Endocrinology
, vol.133
, pp. 1292-1299
-
-
Clapp, C.1
-
20
-
-
0033768751
-
The antiangiogenic factor 16K PRL induces programmed cell death in endothelial cells by caspase activation
-
Martini J.F., et al. The antiangiogenic factor 16K PRL induces programmed cell death in endothelial cells by caspase activation. Mol. Endocrinol. 14 (2000) 1536-1549
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1536-1549
-
-
Martini, J.F.1
-
21
-
-
17944390371
-
Prolactin in eyes of patients with retinopathy of prematurity: implications for vascular regression
-
Dueñas Z., et al. Prolactin in eyes of patients with retinopathy of prematurity: implications for vascular regression. Invest. Ophthalmol. Vis. Sci. 45 (2004) 2049-2055
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 2049-2055
-
-
Dueñas, Z.1
-
22
-
-
0026566153
-
A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells
-
Clapp C., and Weiner R. A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells. Endocrinology 130 (1992) 1380-1386
-
(1992)
Endocrinology
, vol.130
, pp. 1380-1386
-
-
Clapp, C.1
Weiner, R.2
-
24
-
-
0029071065
-
Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the anti-angiogenic factor 16kDa N-terminal fragment of prolactin
-
D'Angelo G., et al. Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the anti-angiogenic factor 16kDa N-terminal fragment of prolactin. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 6374-6378
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 6374-6378
-
-
D'Angelo, G.1
-
25
-
-
0033304596
-
16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells
-
D'Angelo G., et al. 16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells. Mol. Endocrinol. 13 (1999) 692-704
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 692-704
-
-
D'Angelo, G.1
-
26
-
-
0034473913
-
Nitric oxide and angiogenesis
-
Ziche M., and Morbidelli L. Nitric oxide and angiogenesis. J. Neurooncol. 50 (2000) 139-148
-
(2000)
J. Neurooncol.
, vol.50
, pp. 139-148
-
-
Ziche, M.1
Morbidelli, L.2
-
27
-
-
2542502015
-
Nitric oxide in vascular biology
-
Walford G., and Loscalzo J. Nitric oxide in vascular biology. J. Thromb. Haemost. 1 (2003) 2112-2118
-
(2003)
J. Thromb. Haemost.
, vol.1
, pp. 2112-2118
-
-
Walford, G.1
Loscalzo, J.2
-
28
-
-
24744472074
-
16-kDa prolactin down-regulates inducible nitric oxide synthase expression through inhibition of the signal transducer and activator of transcription 1/IFN regulatory-pathway
-
Lee S.-H., et al. 16-kDa prolactin down-regulates inducible nitric oxide synthase expression through inhibition of the signal transducer and activator of transcription 1/IFN regulatory-pathway. Cancer Res. 65 (2005) 7984-7992
-
(2005)
Cancer Res.
, vol.65
, pp. 7984-7992
-
-
Lee, S.-H.1
-
29
-
-
0042835765
-
The antiangiogenic factor 16K human prolactin induces caspase-dependent apoptosis by a mechanism that requires activation of nuclear factor-kappaB
-
Tabruyn S.P. The antiangiogenic factor 16K human prolactin induces caspase-dependent apoptosis by a mechanism that requires activation of nuclear factor-kappaB. Mol. Endocrinol. 17 (2003) 1815-1823
-
(2003)
Mol. Endocrinol.
, vol.17
, pp. 1815-1823
-
-
Tabruyn, S.P.1
-
30
-
-
0242413723
-
Hypoxia inhibits expression of prolactin and secretion of cathepsin-D by the GH4C1 pituitary adenoma cell line
-
Cosio G., et al. Hypoxia inhibits expression of prolactin and secretion of cathepsin-D by the GH4C1 pituitary adenoma cell line. Lab. Invest. 83 (2003) 1627-1636
-
(2003)
Lab. Invest.
, vol.83
, pp. 1627-1636
-
-
Cosio, G.1
-
31
-
-
0036554644
-
Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism
-
Helmlinger G., et al. Acid production in glycolysis-impaired tumors provides new insights into tumor metabolism. Clin. Cancer Res. 8 (2002) 1284-1291
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 1284-1291
-
-
Helmlinger, G.1
-
32
-
-
0030670222
-
Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene
-
Horseman N.D., et al. Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene. EMBO J. 16 (1997) 6926-6935
-
(1997)
EMBO J.
, vol.16
, pp. 6926-6935
-
-
Horseman, N.D.1
-
33
-
-
0027236844
-
Molecular basis of the little mouse phenotype and implications for cell type-specific growth
-
Lin S.C., et al. Molecular basis of the little mouse phenotype and implications for cell type-specific growth. Nature 364 (1993) 208-213
-
(1993)
Nature
, vol.364
, pp. 208-213
-
-
Lin, S.C.1
-
34
-
-
0025016794
-
Molecular mechanism of growth hormone (GH) deficiency in the spontaneous dwarf rat: detection of abnormal splicing of GH messenger ribonucleic acid by the polymerase chain reaction
-
Takeuchi T., et al. Molecular mechanism of growth hormone (GH) deficiency in the spontaneous dwarf rat: detection of abnormal splicing of GH messenger ribonucleic acid by the polymerase chain reaction. Endocrinology 126 (1990) 31-38
-
(1990)
Endocrinology
, vol.126
, pp. 31-38
-
-
Takeuchi, T.1
-
35
-
-
12644257576
-
A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)
-
Zhou Y., et al. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse). Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 13215-13220
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13215-13220
-
-
Zhou, Y.1
-
36
-
-
0142122287
-
Retinal and choroidal angiogenesis: pathophysiology and strategies for inhibition
-
Das A., and McGuire P. Retinal and choroidal angiogenesis: pathophysiology and strategies for inhibition. Prog. Retin. Eye Res. 22 (2003) 721-748
-
(2003)
Prog. Retin. Eye Res.
, vol.22
, pp. 721-748
-
-
Das, A.1
McGuire, P.2
-
37
-
-
24644455356
-
Prolactins are natural inhibitors of angiogenesis in the retina
-
Aranda J., et al. Prolactins are natural inhibitors of angiogenesis in the retina. Invest. Ophthalmol. Vis. Sci. 46 (2005) 2947-2953
-
(2005)
Invest. Ophthalmol. Vis. Sci.
, vol.46
, pp. 2947-2953
-
-
Aranda, J.1
-
38
-
-
0020066981
-
Patterns of radioactivity in the eyes of rats after injections of iodinated prolactin
-
O'Steen W.K., and Sundberg D.K. Patterns of radioactivity in the eyes of rats after injections of iodinated prolactin. Ophthalmic Res. 14 (1982) 54-62
-
(1982)
Ophthalmic Res.
, vol.14
, pp. 54-62
-
-
O'Steen, W.K.1
Sundberg, D.K.2
-
39
-
-
0034994847
-
Expression of prolactin gene and secretion of prolactin by rat retinal capillary endothelial cells
-
Ochoa A., et al. Expression of prolactin gene and secretion of prolactin by rat retinal capillary endothelial cells. Invest. Ophthalmol. Vis. Sci. 42 (2001) 1639-1645
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, pp. 1639-1645
-
-
Ochoa, A.1
-
40
-
-
0342522141
-
Inhibition of rat corneal angiogenesis by 16-kDa prolactin and by endogenous prolactin-like molecules
-
Dueñas Z., et al. Inhibition of rat corneal angiogenesis by 16-kDa prolactin and by endogenous prolactin-like molecules. Invest. Ophthalmol. Vis. Sci. 40 (1999) 2498-2505
-
(1999)
Invest. Ophthalmol. Vis. Sci.
, vol.40
, pp. 2498-2505
-
-
Dueñas, Z.1
-
41
-
-
0034085171
-
Involution of retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group
-
Repka M.X., et al. Involution of retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch. Ophthalmol. 118 (2000) 645-649
-
(2000)
Arch. Ophthalmol.
, vol.118
, pp. 645-649
-
-
Repka, M.X.1
-
42
-
-
0034853095
-
Association of human milk feedings with a reduction in retinopathy of prematurity among very low birthweight infants
-
Hylander M.A., et al. Association of human milk feedings with a reduction in retinopathy of prematurity among very low birthweight infants. J. Perinatol. 21 (2001) 356-362
-
(2001)
J. Perinatol.
, vol.21
, pp. 356-362
-
-
Hylander, M.A.1
-
43
-
-
0021082213
-
Accumulation of prolactin in maternal milk and its transfer to circulation of neonate rat: a review
-
Grosvenor C.E., and Whitworth N.S. Accumulation of prolactin in maternal milk and its transfer to circulation of neonate rat: a review. Endocrinol. Exp. 17 (1983) 271-286
-
(1983)
Endocrinol. Exp.
, vol.17
, pp. 271-286
-
-
Grosvenor, C.E.1
Whitworth, N.S.2
-
44
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D., and Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86 (1996) 353-364
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
45
-
-
0142217202
-
Angiogenesis in endocrine tumors
-
Turner H.E., et al. Angiogenesis in endocrine tumors. Endocr. Rev. 24 (2003) 600-632
-
(2003)
Endocr. Rev.
, vol.24
, pp. 600-632
-
-
Turner, H.E.1
-
46
-
-
33646016582
-
A molecular mimic demonstrates that phosphorylated human prolactin is a potent anti-angiogenic hormone
-
Ueda E., et al. A molecular mimic demonstrates that phosphorylated human prolactin is a potent anti-angiogenic hormone. Endocr. Relat. Cancer 13 (2006) 95-111
-
(2006)
Endocr. Relat. Cancer
, vol.13
, pp. 95-111
-
-
Ueda, E.1
-
47
-
-
0033827335
-
Structural and functional effects of high prolactin levels on injured endothelial cells
-
Merkle C.J., et al. Structural and functional effects of high prolactin levels on injured endothelial cells. Endocrine 13 (2000) 37-46
-
(2000)
Endocrine
, vol.13
, pp. 37-46
-
-
Merkle, C.J.1
-
48
-
-
0033920198
-
Human umbilical vein endothelial cells express multiple prolactin isoforms
-
Corbacho A.M., et al. Human umbilical vein endothelial cells express multiple prolactin isoforms. J. Endocrinol. 166 (2000) 53-62
-
(2000)
J. Endocrinol.
, vol.166
, pp. 53-62
-
-
Corbacho, A.M.1
-
49
-
-
0025851391
-
Heterogeneity of serum and amniotic fluid prolactin in humans
-
Fukuoka H., et al. Heterogeneity of serum and amniotic fluid prolactin in humans. Horm. Res. 35 Suppl. 1 (1991) 58-63
-
(1991)
Horm. Res.
, vol.35
, Issue.SUPPL. 1
, pp. 58-63
-
-
Fukuoka, H.1
-
50
-
-
0028217575
-
Human growth hormone (hGH)-(44-191), a reportedly diabetogenic fragment of hGH, circulates in human blood: measurement by radioimmunoassay
-
Sinha Y.N., and Jacobsen B.P. Human growth hormone (hGH)-(44-191), a reportedly diabetogenic fragment of hGH, circulates in human blood: measurement by radioimmunoassay. J. Clin. Endocrinol. Metab. 78 (1994) 1411-1418
-
(1994)
J. Clin. Endocrinol. Metab.
, vol.78
, pp. 1411-1418
-
-
Sinha, Y.N.1
Jacobsen, B.P.2
-
51
-
-
0028788968
-
A 14-kilodalton prolactin-like fragment is secreted by the hypothalamo-neurohypophyseal system of the rat
-
Torner L., et al. A 14-kilodalton prolactin-like fragment is secreted by the hypothalamo-neurohypophyseal system of the rat. Endocrinology 136 (1995) 5454-5460
-
(1995)
Endocrinology
, vol.136
, pp. 5454-5460
-
-
Torner, L.1
-
52
-
-
0028033044
-
The prolactin gene is expressed in the hypothalamic-neurohypophyseal system and the protein is processed into a 14-kDa fragment with activity like 16-kDa prolactin
-
Clapp C., et al. The prolactin gene is expressed in the hypothalamic-neurohypophyseal system and the protein is processed into a 14-kDa fragment with activity like 16-kDa prolactin. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 10384-10388
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 10384-10388
-
-
Clapp, C.1
-
53
-
-
0034607717
-
Proteolytic cleavage confers nitric oxide synthase inducing activity upon prolactin
-
Corbacho A.M., et al. Proteolytic cleavage confers nitric oxide synthase inducing activity upon prolactin. J. Biol. Chem. 275 (2000) 13183-13186
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13183-13186
-
-
Corbacho, A.M.1
-
54
-
-
0027320965
-
Growth hormone and prolactin variants in normal subjects. Relative proportions in morning and afternoon samples
-
Warner M.D., et al. Growth hormone and prolactin variants in normal subjects. Relative proportions in morning and afternoon samples. Horm. Metab. Res. 25 (1993) 425-429
-
(1993)
Horm. Metab. Res.
, vol.25
, pp. 425-429
-
-
Warner, M.D.1
-
55
-
-
0034052502
-
Structure and properties of members of the hGH family: a review
-
Lewis U.J., et al. Structure and properties of members of the hGH family: a review. Endocr. J. 47 (2000) S1-S8
-
(2000)
Endocr. J.
, vol.47
-
-
Lewis, U.J.1
-
56
-
-
23444431656
-
Solution structure of human prolactin
-
Teilum K., et al. Solution structure of human prolactin. J. Mol. Biol. 351 (2005) 810-823
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 810-823
-
-
Teilum, K.1
-
57
-
-
33646065935
-
Crystal structure and site 1 binding energetics of human placental lactogen
-
Walsh S.T., and Kossiakoff A.A. Crystal structure and site 1 binding energetics of human placental lactogen. J. Mol. Biol. 358 (2006) 773-784
-
(2006)
J. Mol. Biol.
, vol.358
, pp. 773-784
-
-
Walsh, S.T.1
Kossiakoff, A.A.2
|