-
1
-
-
4644370973
-
New therapies for muscular dystrophy: Cautious optimism
-
Cossu G, Sampaolesi M. New therapies for muscular dystrophy: cautious optimism. Trends Mol Med. 2004;10:516-520.
-
(2004)
Trends Mol Med
, vol.10
, pp. 516-520
-
-
Cossu, G.1
Sampaolesi, M.2
-
2
-
-
21244476011
-
AAV-mediated gene transfer for treatment of hemophilia
-
Wang L, Herzog RW. AAV-mediated gene transfer for treatment of hemophilia. Curr Gene Ther. 2005;5:349-360.
-
(2005)
Curr Gene Ther
, vol.5
, pp. 349-360
-
-
Wang, L.1
Herzog, R.W.2
-
3
-
-
5444275097
-
Immune responses to gene therapy vectors: Influence on vector function and effector mechanisms
-
Bessis N, GarciaCozar FJ, Boissier MC. Immune responses to gene therapy vectors: influence on vector function and effector mechanisms. Gene Ther. 2004;11(suppl 1):S10-S17.
-
(2004)
Gene Ther
, vol.11
, Issue.1 SUPPL.
-
-
Bessis, N.1
Garciacozar, F.J.2
Boissier, M.C.3
-
4
-
-
0038805302
-
Immunity to adenovirus and adeno-associated viral vectors: Implications for gene therapy
-
Jooss K, Chirmule N. Immunity to adenovirus and adeno-associated viral vectors: implications for gene therapy. Gene Ther. 2003;10:955-963.
-
(2003)
Gene Ther
, vol.10
, pp. 955-963
-
-
Jooss, K.1
Chirmule, N.2
-
5
-
-
0037103167
-
Dangerous liaisons: The role of "danger" signals in the immune response to gene therapy
-
Brown BD, Lillicrap D. Dangerous liaisons: the role of "danger" signals in the immune response to gene therapy. Blood. 2002;100:1133-1140.
-
(2002)
Blood
, vol.100
, pp. 1133-1140
-
-
Brown, B.D.1
Lillicrap, D.2
-
6
-
-
0034849318
-
Muscle-directed gene transfer and transient immune suppression result in sustained partial correction of canine hemophilia B caused by a null mutation
-
Herzog RW, Mount JD, Arruda VR, High KA, Lothrop CD Jr. Muscle-directed gene transfer and transient immune suppression result in sustained partial correction of canine hemophilia B caused by a null mutation. Mol Ther. 2001;4:192-200.
-
(2001)
Mol Ther
, vol.4
, pp. 192-200
-
-
Herzog, R.W.1
Mount, J.D.2
Arruda, V.R.3
High, K.A.4
Lothrop Jr., C.D.5
-
7
-
-
0034749458
-
Successful interference with cellular immune responses to immunogenic proteins encoded by recombinant viral vectors
-
Sarukhan A, Camugli S, Gjata B, von Boehmer H, Danos O, Jooss K. Successful interference with cellular immune responses to immunogenic proteins encoded by recombinant viral vectors. J Virol. 2001;75:269-277.
-
(2001)
J Virol
, vol.75
, pp. 269-277
-
-
Sarukhan, A.1
Camugli, S.2
Gjata, B.3
Von Boehmer, H.4
Danos, O.5
Jooss, K.6
-
8
-
-
0035025762
-
Mixed chimerism and transplant tolerance
-
Sykes M. Mixed chimerism and transplant tolerance. Immunity. 2001;14:417-424.
-
(2001)
Immunity
, vol.14
, pp. 417-424
-
-
Sykes, M.1
-
9
-
-
0842310011
-
Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity
-
Nikolic B, Takeuchi Y, Leykin I, Fudaba Y, Smith RN, Sykes M. Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity. Diabetes. 2004;53:376-383.
-
(2004)
Diabetes
, vol.53
, pp. 376-383
-
-
Nikolic, B.1
Takeuchi, Y.2
Leykin, I.3
Fudaba, Y.4
Smith, R.N.5
Sykes, M.6
-
10
-
-
20444456279
-
Treatment of severe autoimmune disease by stem-cell transplantation
-
Sykes M, Nikolic B. Treatment of severe autoimmune disease by stem-cell transplantation. Nature. 2005;435:620-627.
-
(2005)
Nature
, vol.435
, pp. 620-627
-
-
Sykes, M.1
Nikolic, B.2
-
11
-
-
0141693112
-
Induction of T cell tolerance to a protein expressed in the cytoplasm through retroviral-mediated gene transfer
-
Tian C, Bagley J, Kaye J, Iacomini J. Induction of T cell tolerance to a protein expressed in the cytoplasm through retroviral-mediated gene transfer. J Gene Med. 2003;5:359-365.
-
(2003)
J Gene Med
, vol.5
, pp. 359-365
-
-
Tian, C.1
Bagley, J.2
Kaye, J.3
Iacomini, J.4
-
12
-
-
0141856330
-
Engraftment of retroviral EGFP-transduced bone marrow in mice prevents rejection of EGFP-transgenic skin grafts
-
Andersson G, Denaro M, Johnson K, et al. Engraftment of retroviral EGFP-transduced bone marrow in mice prevents rejection of EGFP-transgenic skin grafts. Mol Ther. 2003;8:385-391.
-
(2003)
Mol Ther
, vol.8
, pp. 385-391
-
-
Andersson, G.1
Denaro, M.2
Johnson, K.3
-
13
-
-
0034071426
-
Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment
-
Wekerle T, Kurtz J, Ito H, et al. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nat Med. 2000;6:464-469.
-
(2000)
Nat Med
, vol.6
, pp. 464-469
-
-
Wekerle, T.1
Kurtz, J.2
Ito, H.3
-
14
-
-
0036911130
-
Dominant transplantation tolerance impairs CD8+ T cell function but not expansion
-
Lin CY, Graca L, Cobbold SP, Waldmann H. Dominant transplantation tolerance impairs CD8+ T cell function but not expansion. Nat Immunol. 2002;3:1208-1213.
-
(2002)
Nat Immunol
, vol.3
, pp. 1208-1213
-
-
Lin, C.Y.1
Graca, L.2
Cobbold, S.P.3
Waldmann, H.4
-
15
-
-
3042722261
-
Exploiting tolerance processes in transplantation
-
Waldmann H, Cobbold S. Exploiting tolerance processes in transplantation. Science. 2004;305:209-212.
-
(2004)
Science
, vol.305
, pp. 209-212
-
-
Waldmann, H.1
Cobbold, S.2
-
17
-
-
16844365788
-
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
-
Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol. 2005;6:345-352.
-
(2005)
Nat Immunol
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
18
-
-
16844363097
-
A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
-
Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol. 2005;6:331-337.
-
(2005)
Nat Immunol
, vol.6
, pp. 331-337
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
20
-
-
0346690399
-
Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia
-
Trenado A, Charlotte F, Fisson S, et al. Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia. J Clin Invest. 2003;112:1688-1696.
-
(2003)
J Clin Invest
, vol.112
, pp. 1688-1696
-
-
Trenado, A.1
Charlotte, F.2
Fisson, S.3
-
21
-
-
9444280125
-
L-selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
-
Taylor PA, Panoskaltsis-Mortari A, Swedin JM, et al. L-selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection. Blood. 2004;104:3804-3812.
-
(2004)
Blood
, vol.104
, pp. 3804-3812
-
-
Taylor, P.A.1
Panoskaltsis-Mortari, A.2
Swedin, J.M.3
-
22
-
-
2542496868
-
Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes
-
Joffre O, Gorsse N, Romagnoli P, Hudrisier D, van Meerwijk JP. Induction of antigen-specific tolerance to bone marrow allografts with CD4+CD25+ T lymphocytes. Blood. 2004;103:4216-4221.
-
(2004)
Blood
, vol.103
, pp. 4216-4221
-
-
Joffre, O.1
Gorsse, N.2
Romagnoli, P.3
Hudrisier, D.4
Van Meerwijk, J.P.5
-
23
-
-
16844362608
-
Mechanisms of suppression by suppressor T cells
-
von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol. 2005;6:338-344.
-
(2005)
Nat Immunol
, vol.6
, pp. 338-344
-
-
Von Boehmer, H.1
-
24
-
-
0037062420
-
Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in antimyelin basic protein T cell receptor transgenic mice
-
Hori S, Haury M, Coutinho A, Demengeot J. Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in antimyelin basic protein T cell receptor transgenic mice. Proc Natl Acad Sci U S A. 2002;99:8213-8218.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8213-8218
-
-
Hori, S.1
Haury, M.2
Coutinho, A.3
Demengeot, J.4
-
25
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton AM, Shevach EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med. 1998;188:287-296.
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
26
-
-
2942692039
-
CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
-
Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM. CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med. 2004;199:1467-1477.
-
(2004)
J Exp Med
, vol.199
, pp. 1467-1477
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
Toy, P.4
Steinman, R.M.5
-
27
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang Q, Henriksen KJ, Bi M, et al. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med. 2004;199:1455-1465.
-
(2004)
J Exp Med
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
-
28
-
-
0344737700
-
CD4+CD25+ regulatory T cells inhibit immune-mediated transgene rejection
-
Gross DA, Leboeuf M, Gjata B, Danos O, Davoust J. CD4+CD25+ regulatory T cells inhibit immune-mediated transgene rejection. Blood. 2003;102:4326-4328.
-
(2003)
Blood
, vol.102
, pp. 4326-4328
-
-
Gross, D.A.1
Leboeuf, M.2
Gjata, B.3
Danos, O.4
Davoust, J.5
-
29
-
-
0036906477
-
Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes
-
Thery C, Duban L, Segura E, Veron P, Lantz O, Amigorena S. Indirect activation of naive CD4+ T cells by dendritic cell-derived exosomes. Nat Immunol. 2002;3:1156-1162.
-
(2002)
Nat Immunol
, vol.3
, pp. 1156-1162
-
-
Thery, C.1
Duban, L.2
Segura, E.3
Veron, P.4
Lantz, O.5
Amigorena, S.6
-
30
-
-
0041884743
-
Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state
-
Fisson S, Darrasse-Jeze G, Litvinova E, et al. Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state. J Exp Med. 2003;198:737-746.
-
(2003)
J Exp Med
, vol.198
, pp. 737-746
-
-
Fisson, S.1
Darrasse-Jeze, G.2
Litvinova, E.3
-
31
-
-
0037804775
-
Nonmyeloablative conditioning is sufficient to allow engraftment of EGFP-expressing bone marrow and subsequent acceptance of EGFP-transgenic skin grafts in mice
-
Andersson G, Illigens BM, Johnson KW, et al. Nonmyeloablative conditioning is sufficient to allow engraftment of EGFP-expressing bone marrow and subsequent acceptance of EGFP-transgenic skin grafts in mice. Blood. 2003;101:4305-4312.
-
(2003)
Blood
, vol.101
, pp. 4305-4312
-
-
Andersson, G.1
Illigens, B.M.2
Johnson, K.W.3
-
32
-
-
0017081647
-
A comparison of the survival of H-Y incompatible ear, tail, and body skin grafts
-
Sena J, Wachtel SS, Murphy G. A comparison of the survival of H-Y incompatible ear, tail, and body skin grafts. Transplantation. 1976;21:412-416.
-
(1976)
Transplantation
, vol.21
, pp. 412-416
-
-
Sena, J.1
Wachtel, S.S.2
Murphy, G.3
-
33
-
-
0016691484
-
Differences in the rejection of trunk skin and tail skin allografts involving weak histocompatibility loci
-
Mathieson BJ, Flaherty L, Bennett D, Boyse EA. Differences in the rejection of trunk skin and tail skin allografts involving weak histocompatibility loci. Transplantation. 1975;19:525-527.
-
(1975)
Transplantation
, vol.19
, pp. 525-527
-
-
Mathieson, B.J.1
Flaherty, L.2
Bennett, D.3
Boyse, E.A.4
-
34
-
-
0037026001
-
CD4(+)CD25(+) immunoregulatory T cells: New therapeutics for graft-versus-host disease
-
Cohen JL, Trenado A, Vasey D, Klatzmann D, Salomon BL. CD4(+)CD25(+) immunoregulatory T cells: new therapeutics for graft-versus-host disease. J Exp Med. 2002;196:401-406.
-
(2002)
J Exp Med
, vol.196
, pp. 401-406
-
-
Cohen, J.L.1
Trenado, A.2
Vasey, D.3
Klatzmann, D.4
Salomon, B.L.5
-
35
-
-
15944425718
-
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset
-
Kleinewietfeld M, Puentes F, Borsellino G, Battistini L, Rotzschke O, Falk K. CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. Blood. 2005;105:2877-2886.
-
(2005)
Blood
, vol.105
, pp. 2877-2886
-
-
Kleinewietfeld, M.1
Puentes, F.2
Borsellino, G.3
Battistini, L.4
Rotzschke, O.5
Falk, K.6
-
36
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan MS, Boesteanu A, Reed AJ, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol. 2001;2:301-306.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.S.1
Boesteanu, A.2
Reed, A.J.3
-
38
-
-
0035421654
-
Cutting edge: Control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells
-
Piccirillo CA, Shevach EM. Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol. 2001;167:1137-1140.
-
(2001)
J Immunol
, vol.167
, pp. 1137-1140
-
-
Piccirillo, C.A.1
Shevach, E.M.2
-
39
-
-
12244285937
-
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo
-
Chen ML, Pittet MJ, Gorelik L, et al. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo. Proc Natl Acad Sci U S A. 2005;102:419-424.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 419-424
-
-
Chen, M.L.1
Pittet, M.J.2
Gorelik, L.3
-
40
-
-
17544386950
-
Establishing immunological tolerance through the induction of molecular chimerism
-
Bagley J, Bracy JL, Tian C, Kang ES, Iacomini J. Establishing immunological tolerance through the induction of molecular chimerism. Front Biosci. 2002;7:d1331-d1337.
-
(2002)
Front Biosci
, vol.7
-
-
Bagley, J.1
Bracy, J.L.2
Tian, C.3
Kang, E.S.4
Iacomini, J.5
-
41
-
-
9644252861
-
Prevention of type 1 diabetes by gene therapy
-
Tian C, Bagley J, Cretin N, Seth N, Wucherpfennig KW, Iacomini J. Prevention of type 1 diabetes by gene therapy. J Clin Invest. 2004;114:969-978.
-
(2004)
J Clin Invest
, vol.114
, pp. 969-978
-
-
Tian, C.1
Bagley, J.2
Cretin, N.3
Seth, N.4
Wucherpfennig, K.W.5
Iacomini, J.6
-
42
-
-
0028564889
-
Engraftment of normal murine marrow into nonmyeloablated host mice
-
Quesenberry PJ, Ramshaw H, Crittenden RB, et al. Engraftment of normal murine marrow into nonmyeloablated host mice. Blood Cells. 1994;20:348-350.
-
(1994)
Blood Cells
, vol.20
, pp. 348-350
-
-
Quesenberry, P.J.1
Ramshaw, H.2
Crittenden, R.B.3
-
43
-
-
0031053834
-
Stem cell transplantation in the normal nonmyeloablated host: Relationship between cell dose, schedule, and engraftment
-
Rao SS, Peters SO, Crittenden RB, Stewart FM, Ramshaw HS, Quesenberry PJ. Stem cell transplantation in the normal nonmyeloablated host: relationship between cell dose, schedule, and engraftment. Exp Hematol. 1997;25:114-121.
-
(1997)
Exp Hematol
, vol.25
, pp. 114-121
-
-
Rao, S.S.1
Peters, S.O.2
Crittenden, R.B.3
Stewart, F.M.4
Ramshaw, H.S.5
Quesenberry, P.J.6
-
44
-
-
0037313473
-
The complementary roles of deletion and regulation in transplantation tolerance
-
Lechler RI, Garden OA, Turka LA. The complementary roles of deletion and regulation in transplantation tolerance. Nat Rev Immunol. 2003;3:147-158.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 147-158
-
-
Lechler, R.I.1
Garden, O.A.2
Turka, L.A.3
-
45
-
-
32644482551
-
Clinical application of expanded CD4(+)25(+) cells
-
June CH, Blazar BR. Clinical application of expanded CD4(+)25(+) cells. Semin Immunol. 2006;18:78-88.
-
(2006)
Semin Immunol
, vol.18
, pp. 78-88
-
-
June, C.H.1
Blazar, B.R.2
-
46
-
-
32644459908
-
Antigen-specific regulatory T cells - Ex vivo expansion and therapeutic potential
-
Masteller EL, Tang Q, Bluestone JA. Antigen-specific regulatory T cells - ex vivo expansion and therapeutic potential. Semin Immunol. 2006;18:103-110.
-
(2006)
Semin Immunol
, vol.18
, pp. 103-110
-
-
Masteller, E.L.1
Tang, Q.2
Bluestone, J.A.3
-
47
-
-
32644486426
-
Therapeutic potential of self-antigen-specific CD4(+)CD25(+) regulatory T cells selected in vitro from a polyclonal repertoire
-
Fisson S, Djelti F, Trenado A, et al. Therapeutic potential of self-antigen-specific CD4(+)CD25(+) regulatory T cells selected in vitro from a polyclonal repertoire. Eur J Immunol. 2006;36:817-827.
-
(2006)
Eur J Immunol
, vol.36
, pp. 817-827
-
-
Fisson, S.1
Djelti, F.2
Trenado, A.3
-
48
-
-
12744262844
-
Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes
-
Jaeckel E, von Boehmer H, Manns MP. Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes. Diabetes. 2005;54:306-310.
-
(2005)
Diabetes
, vol.54
, pp. 306-310
-
-
Jaeckel, E.1
Von Boehmer, H.2
Manns, M.P.3
-
49
-
-
21144436219
-
Regulatory T cells, derived from naive CD4+CD25- T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance
-
Chai JG, Xue SA, Coe D, et al. Regulatory T cells, derived from naive CD4+CD25- T cells by in vitro Foxp3 gene transfer, can induce transplantation tolerance. Transplantation. 2005;79:1310-1316.
-
(2005)
Transplantation
, vol.79
, pp. 1310-1316
-
-
Chai, J.G.1
Xue, S.A.2
Coe, D.3
-
50
-
-
27644449311
-
The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs
-
Allan SE, Passerini L, Bacchetta R, et al. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. J Clin Invest. 2005;115:3276-3284.
-
(2005)
J Clin Invest
, vol.115
, pp. 3276-3284
-
-
Allan, S.E.1
Passerini, L.2
Bacchetta, R.3
-
51
-
-
85047689740
-
Induction of dominant transplantation tolerance by an altered peptide ligand of the male antigen Dby
-
Chen TC, Waldmann H, Fairchild PJ. Induction of dominant transplantation tolerance by an altered peptide ligand of the male antigen Dby. J Clin Invest. 2004;113:1754-1762.
-
(2004)
J Clin Invest
, vol.113
, pp. 1754-1762
-
-
Chen, T.C.1
Waldmann, H.2
Fairchild, P.J.3
-
52
-
-
29244435493
-
Inducing and expanding regulatory T cell populations by foreign antigen
-
Kretschmer K, Apostolou I, Hawiger D, Khazaie K, Nussenzweig MC, von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat Immunol. 2005;6:1219-1227.
-
(2005)
Nat Immunol
, vol.6
, pp. 1219-1227
-
-
Kretschmer, K.1
Apostolou, I.2
Hawiger, D.3
Khazaie, K.4
Nussenzweig, M.C.5
Von Boehmer, H.6
|