Preparation of animals for use in the laboratory: Issues and challenges for the institutional animal care and use committee (IACUC)

ILAR Journal

Volumn 47, Issue 4, 2006, Pages 370-375

  Schapiro, Steven J ^a   Everitt, Jeffrey I ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Acclimation; Desensitization; Habituation; Homeostasis; IACUC; Subject selection; Variability

Indexed keywords

ACCLIMATIZATION; ANIMAL BEHAVIOR; ANIMAL CARE; ANIMAL HEALTH; ANIMAL HOUSING; ANIMAL TESTING REDUCTION; ANIMAL TESTING REFINEMENT; ANIMAL TESTING REPLACEMENT; ARTICLE; EXPERIMENTAL ANIMAL WELFARE; EXPERIMENTATION; HABITUATION; HOMEOSTASIS; IN VIVO STUDY; LONGITUDINAL STUDY; MEDICAL RESEARCH; NONHUMAN; QUALITY CONTROL; SAMPLING;

ANIMALIA;

EID: 33748679896     PISSN: 10842020     EISSN: None     Source Type: Journal    
DOI: 10.1093/ilar.47.4.370     Document Type: Article

References (20)

1. Bloomsmith MA, Schapiro SJ, Strobert EA. 2006. Preparing chimpanzees for laboratory research. ILAR J 47:316-325.
2. Capitanio JP, Kyes RC, Fairbanks LA. 2006. Considerations in the selection and conditioning of Old World monkeys for laboratory research: Animals from domestic sources. ILAR J 47:294-306.
3. Conour LA, Murray KA, Brown MJ. 2006. Preparation of animals for research: Issues to consider for rodents and rabbits. ILAR J 47:283-293.
4. Hagelin J, Hau J, Carlsson HE. 2003. The refining influence of ethics committees on animal experimentation in Sweden. Lab Anim 37:10-18.
5. Hau J, Carlsson HE, Hagelin, J. 2001. Animal research: Ethics committees have influenced animal experiments in Sweden. Br Med J 322:1604.
6. Ihrig M, Tassinary LG, Bernacky B, Keeling ME. 2001. Hematologic and serum biochemical reference intervals for the chimpanzee (Pan troglodytes) categorized by age and sex. Comp Med 51:30-37.
7. King-Herbert AP, Hesterberg TW, Thevenaz PH, Hamm TE, Moss OR, Janszen DB, Everitt JI. 1997. Effects of immobilization restraint on Syrian golden hamsters. Lab Anim Sci 47:362-366.
8. Lambeth SP, Perlman JE, Thiele E, Schapiro SJ. 2005. Changes in hematology and blood chemistry parameters in captive chimpanzees (Pan troglodytes) as a function of blood sampling technique: Trained vs. anesthetized samples. Am J Primatol 66(Suppl 1):182-183.
9. Meunier LD. 2006. Selection, acclimation, training, and preparation of dogs for the research setting. ILAR J 47:326-347.
10. Narciso SP, Nadziejko E, Chen LC, Gordon T, Nadsiejko C. 2003. Adaptation to stress induced by restraining rats and mice in nose-only inhalation holders. Inhal Toxicol 15:1133-1143.
11. Nicholls AW, Mortishire-Smith RJ, Nicholson JK. 2003. NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats. Chem Res Toxicol 16:1395-1404.
12. NRC [National Research Council]. 1997. Chimpanzees in Research: Strategies for Their Ethical Care, Management, and Use. Washington DC: National Academy Press.
13. Obernier JA, Baldwin RL. 2006. Establishing an appropriate period of acclimatization following transportation of laboratory animals. ILAR J 47:364-369.
14. Pranger LA, Maier A, Coleman K, Lambeth SP, Perlman JE, Thiele E, McMillan JL, Schapiro SJ. 2006. Venipuncture training using positive reinforcement training techniques: A comparison of chimpanzees and rhesus macaques. Am J Primatol (In Press).
15. Russell WMS, Burch RL 1959. The Principles of Humane Experimental Technique. London: Methuen & Co. LTD. [Reissued: 1992, Universities Federation for Animal Welfare, Herts, England.] http://altweb.jhsph.edu/ publications/humane_exp/het-toc.htm.
16. Ruys JD, Mendoza SP, Capitanio JP, Mason WA. 2004. Behavioral and physiological adaptation to repeated chair restraint in rhesus macaques. Physiol Behav 82:205-213.
17. Scipioni Ball R. 2006. Issues to consider for preparing ferrets and cats as research subjects in the laboratory. ILAR J 47:348-357.
18. Smith AC, Swindle MM. 2006. Preparation of swine for the laboratory. ILAR J 47:358-363.
19. Tardif S, Bales K, Williams L, Moeller EL, Abbott D, Schultz-Darken N, Mendoza S, Mason W, Bourgeois S, Ruiz J. 2006. Preparing New World monkeys for laboratory research. ILAR J 47:307-315.
20. Weihe WH. 1998. The impact of stress and discomfort on experimental outcome. Arch Toxicol Suppl 20:47-59.