Integration of a rapid automated solubility classification into early validation of hits obtained by high throughput screening

Journal of Pharmaceutical and Biomedical Analysis

Volumn 42, Issue 4, 2006, Pages 449-454

  Fligge, Thilo A ^a   Schuler, Andrea ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Automation; High throughput; Kinetic solubility; Nephelometry; Solubility classification

Indexed keywords

BIFONAZOLE; BUFFER; CLOTRIMAZOLE; CORTICOSTERONE; DIETHYLSTILBESTROL; ESTRADIOL; LORATADINE; PHENYL GROUP; TESTOSTERONE; VERAPAMIL;

ARTICLE; AUTOMATION; CLASSIFICATION; HIGH THROUGHPUT SCREENING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NEPHELOMETRY; PRIORITY JOURNAL; ROBOTICS; SOLUBILITY; VALIDATION PROCESS;

AUTOMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMBINATORIAL CHEMISTRY TECHNIQUES; MASS SPECTROMETRY; MICROCHEMISTRY; NEPHELOMETRY AND TURBIDIMETRY; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SOLUBILITY;

EID: 33748678161     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.05.004     Document Type: Article

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