The G protein β3 subunit 825C allele is associated with sudden infant death due to infection

Acta Paediatrica, International Journal of Paediatrics

Volumn 95, Issue 9, 2006, Pages 1129-1132

  Opdal, Siri Hauge ^a,b   Melien, Øyvind ^b   Rootwelt, Helge ^b   Vege, Åshild ^a   Arnestad, Marianne ^a   Rognum, Torleiv Ole ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

C825T; G protein subunit 3; Infectious death; SIDS

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN BETA SUBUNIT; G PROTEIN BETA3 SUBUNIT; G-PROTEIN BETA3 SUBUNIT; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN;

ALLELE; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; IMMUNOCOMPETENT CELL; INFANT; INFECTION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SUDDEN INFANT DEATH SYNDROME; CASE CONTROL STUDY; GENETICS; NEWBORN; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; CASE-CONTROL STUDIES; GENOTYPE; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; INFANT; INFANT, NEWBORN; INFECTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SUDDEN INFANT DEATH;

EID: 33748644045     PISSN: 08035253     EISSN: 16512227     Source Type: Journal    
DOI: 10.1080/08035250600580529     Document Type: Article

References (27)

1. Arnestad M, Andersen M, Vege A, Rognum TO. Changes in the epidemiological pattern of sudden infant death syndrome in southeast Norway, 1984-1998: implications for future prevention and research. Arch Dis Child 2001;85:108-15.
2. Stoltenberg L, Saugstad OD, Rognum TO. Sudden infant death syndrome victims show local immunoglobulin M response in tracheal wall and immunoglobulin A response in duodenal mucosa. Pediatr Res 1992;31:372-5.
3. Vege A, Rognum TO, Scott H, Aasen AO, Saugstad OD. SIDS cases have increased levels of interleukin-6 in cerebrospinal fluid. Acta Paediatr 1995;84:193-6.
4. Summers AM, Summers CW, Drucker DB, Hajeer AH, Barson A, Hutchinson IV. Association of IL-10 genotype with sudden infant death syndrome. Hum Immunol 2000;61:1270-3.
5. Opdal SH, Vege A, Stave AK, Rognum TO. The complement component C4 in sudden infant death. Eur J Pediatr 1999;158:210-2.
6. Opdal SH, Opstad A, Vege A, Rognum TO. Il-10 gene polymorphisms are associated with infectious cause of sudden infant death. Hum Immunol 2003;64:1183-9.
7. Stantchev TS, Broder CC. Human immunodeficiency virus type-1 and chemokines: beyond competition for common cellular receptors. Cytokine Growth Factor Rev 2001;12:219-43.
8. Gilman AG. Nobel Lecture. G proteins and regulation of adenylyl cyclase. Biosci Rep 1995;15:65-97.
9. Melien O, Sandnes D, Johansen EJ, Christoffersen T. Effects of pertussis toxin on extracellular signal-regulated kinase activation in hepatocytes by hormones and receptor-independent agents: evidence suggesting a stimulatory role of G(i) proteins at a level distal to receptor coupling. J Cell Physiol 2000;184:27-36.
10. Hurowitz EH, Melnyk JM, Chen YJ, Kouros-Mehr H, Simon MI, Shizuya H. Genomic characterization of the human heterotrimeric G protein alpha, beta, and gamma subunit genes. DNA Res 2000;7:111-20.
11. Siffert W, Rosskopf D, Siffert G, Busch S, Moritz A, Erbel R, et al. Association of a human G-protein β3 subunit variant with hypertension. Nat Genet 1998;18:45-8.
12. Rosskopf D, Koch K, Habich C, Geerdes J, Ludwig A, Wilhelms S, et al. Interaction of Gβ3s, a splice variant of the G-protein Gβ3, with Gγ- and Gα-proteins. Cell Signal 2003;15:479-88.
13. Virchow S, Ansorge N, Rubben H, Siffert G, Siffert W. Enhanced fMLP-stimulated chemotaxis in human neutrophils from individuals carrying the G protein β3 subunit 825 T-allele. FEBS Lett 1998;436:155-8.
14. Virchow S, Ansorge N, Rosskopf D, Rubben H, Siffert W. The G protein β3 subunit splice variant Gβ3-s causes enhanced chemotaxis of human neutrophils in response to interleukin-8. Naunyn Schmiedebergs Arch Pharmacol 1999;360:27-32.
15. Lindemann M, Virchow S, Ramann F, Barsegian V, Kreuzfelder E, Siffert W, et al. The G protein β3 subunit 825T allele is a genetic marker for enhanced T cell response. FEBS Lett 2001;495:82-6.
16. Gregersen M RJ, Laursen H, Baandrup U, Frederiksen P, Gidlund E, Helweg-Larsen K, et al. Pathologic criteria for the Nordic Study of SIDS. In: Rognum TO, editor. Sudden infant death syndrome: new trends in the nineties. Oslo: Scandinavian University Press; 1995. p. 50-8.
17. Arnestad M, Vege A, Rognum TO. Evaluation of diagnostic tools applied in the examination of sudden unexpected deaths in infancy and early childhood. Forensic Sci Int 2002;125:262-8.
18. Farfel Z, Bourne HR, Iiri T. The expanding spectrum of G protein diseases. N Engl J Med 1999;340:1012-20.
19. Smit MJ, Vink C, Verzijl D, Casarosa P, Bruggeman CA, Leurs R. Virally encoded G protein-coupled receptors: targets for potentially innovative anti-viral drug development. Curr Drug Targets 2003;4:431-41.
20. Lindemann M, Barsegian V, Siffert W, Ferencik S, Roggendorf M, Grosse-Wilde H. Role of G protein β3 subunit C825T and HLA class II polymorphisms in the immune response after HBV vaccination. Virology 2002;297:245-52.
21. Sarrazin C, Berg T, Weich V, Mueller T, Frey UH, Zeuzem S, et al. GNB3 C825T polymorphism and response to interferon-alfa/ribavirin treatment in patients with hepatitis C virus genotype 1 (HCV-1) infection. J Hepatol 2005;43:388-93.
22. Braun MC, Kelsall BL. Regulation of interleukin-12 production by G-protein-coupled receptors. Microbes Infect 2001;3:99-107.
23. He J, Gurunathan S, Iwasaki A, Ash-Shaheed B, Kelsall BL. Primary role for Gi protein signaling in the regulation of interleukin 12 production and the induction of T helper cell type 1 responses. J Exp Med 2000;191:1605-10.
24. Pier GB. Role of the cystic fibrosis transmembrane conductance regulator in innate immunity to Pseudomonas aeruginosa infections. Proc Natl Acad Sci U S A 2000;97:8822-8.
25. Swords WE, Ketterer MR, Shao J, Campbell CA, Weiser JN, Apicella MA. Binding of the non-typeable Haemophilus influenzae lipooligosaccharide to the PAF receptor initiates host cell signalling. Cell Microbiol 2001;3:525-36.
26. Siffert W, Forster P, Jockel KH, Mvere DA, Brinkmann B, Naber C, et al. Worldwide ethnic distribution of the G protein β3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals. J Am Soc Nephrol 1999;10:1921-30.
27. 3-subunit and antihypertensive response to a thiazide diuretic. Hypertension 2001;37:739-43.