Mycobacterial codon optimization of the gene encoding the Sm14 antigen of Schistosoma mansoni in recombinant Mycobacterium bovis Bacille Calmette-Guérin enhances protein expression but not protection against cercarial challenge in mice

FEMS Immunology and Medical Microbiology

Volumn 48, Issue 1, 2006, Pages 132-139

  Varaldo, Paula B ^a   Miyaji, Eliane N ^a   Vilar, Monica M ^b   Campos, Adriano S ^b   Dias, Waldely O ^a   Armôa, Geraldo R G ^b   Tendler, Miriam ^b   Leite, Luciana C C ^a   McIntosh, Douglas ^b  

^a INSTITUTO BUTANTAN   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Recombinant Mycobacterium bovis BCG; Schistosomiasis; Sm14

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; PARASITE ANTIGEN; SM14 ANTIGEN; SYNTHETIC DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CERCARIA; CODON; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; IMMUNIZATION; MOUSE; MYCOBACTERIUM; MYCOBACTERIUM BOVIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHISTOSOMA MANSONI; SINGLE DRUG DOSE; SPLEEN CELL;

ANIMALS; BCG VACCINE; CODON; FATTY ACID TRANSPORT PROTEINS; GENE EXPRESSION; HELMINTH PROTEINS; MICE; MICE, INBRED BALB C; MYCOBACTERIUM BOVIS; RECOMBINANT FUSION PROTEINS; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; VACCINES, DNA; VACCINES, SYNTHETIC;

EID: 33748590843     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2006.00133.x     Document Type: Article

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