Tissue-targeting lead generation and optimization from random and directed screening of technetium-99m labeled tripeptide complex libraries in vivo

Chinese Medical Journal

Volumn 119, Issue 17, 2006, Pages 1435-1443

  Zeng, Jun ^a   Liu, Ci Yi ^a   Xie, Wen Hui ^a   Hu, Si Long ^a   Jin, Mu Xiu ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

99mTc labeled; Directed screening; In vivo; Random screening; Tripeptide libraries

Indexed keywords

AMIDE; PEPTIDE LIBRARY; RESIN; TECHNETIUM 99M; TRIPEPTIDE;

ANIMAL EXPERIMENT; ARTICLE; ATOM; CARBOXY TERMINAL SEQUENCE; CHEMICAL MODIFICATION; COMBINATORIAL LIBRARY; DRUG LIVER LEVEL; DRUG METABOLISM; DRUG RESEARCH; DRUG SCREENING; DRUG TISSUE LEVEL; DRUG TUMOR LEVEL; FEMALE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VIVO STUDY; ISOTOPE LABELING; KIDNEY FUNCTION TEST; KIDNEY PARENCHYMA; MOUSE; NONHUMAN; PROTEIN PROCESSING; PROTEIN STRUCTURE; RAT; RAT STRAIN; SIGNAL TRANSDUCTION; TARGET ORGAN; TISSUE DISTRIBUTION; TISSUE SPECIFICITY;

EID: 33748583197     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200609010-00006     Document Type: Article

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