Determination of ergosterol in ganoderma spore lipid from the germinating spores of Ganoderma lucidum by high-performance liquid chromatography

Journal of Agricultural and Food Chemistry

Volumn 54, Issue 17, 2006, Pages 6172-6176

  Yuan, Jian Ping ^a   Wang, Jiang Hai ^a   Liu, Xin ^a   Kuang, Hui Cong ^a   Huang, Xiao Ni ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Ergosterol; Ganoderma lucidum; Ganoderma spore lipid; HPLC; Saponification

Indexed keywords

ERGOSTEROL; LIPID; METHANOL; SODIUM HYDROXIDE;

ARTICLE; CHEMISTRY; FUNGUS SPORE; GANODERMA LUCIDUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; SENSITIVITY AND SPECIFICITY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ERGOSTEROL; HYDROLYSIS; LIPIDS; METHANOL; REISHI; SENSITIVITY AND SPECIFICITY; SODIUM HYDROXIDE; SPORES, FUNGAL;

BACTERIA (MICROORGANISMS); GANODERMA; GANODERMA LUCIDUM;

EID: 33748582280     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf0617059     Document Type: Article

References (33)

1. Wasser, S. P.; Weis, A. L. Therapeutic effects of substances occurring in higher basidiomycetes mushrooms: A modern perspective. Crit. Rev. Immunol. 1999, 19, 65-96.
2. Min, B. S.; Nakamura, N.; Miyashiro, H.; Bae, K. W.; Hattori, M. Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem. Pharm. Bull. 1998, 46, 1607-1612.
3. Huie, C. W.; Di, X. Chromatographic and electrophoretic methods for Lingzhi pharmacologically active components. J. Chromatogr. B 2004, 812, 241-257.
4. Rösecke, J.; König, W. A. Constituents of various wood-rotting basidiomycetes. Phytochemistry 2000, 54, 603-610.
5. Zhang, Y. J.; Mills, G. L.; Nair, M. G. Cyclooxygenase inhibitory and antioxidant compounds from the mycelia of the edible mushroom Grifola frondosa. J. Agric. Food Chem. 2002, 50, 7581-7585.
6. Zhang, Y. J.; Mills, G. L.; Nair, M. G. Cyclooxygenase inhibitory and antioxidant compounds from the fruiting body of an edible mushroom, Agrocybe aegerita. Phytomedicine 2003, 10, 386-390.
7. Borchers, A. T.; Keen, C. L.; Gershwin, M. E. Mushrooms, tumors, and immunity: An update. Exp. Biol. Med. 2004, 229, 393-406.
8. Yazawa, Y.; Yokota, M.; Sugiyama, K. Antitumor promoting effect of an active component of polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A. Biol. Pharm. Bull. 2000, 23, 1298-1302.
9. Takaku, T.; Kimura, Y.; Okuda, H. Isolation of an antitumor compound from Agaricus blazei murill and its mechanism of action. J. Nutr. 2001, 131, 1409-1413.
10. Subbiah, M. T. R.; Abplanalp, W. Ergosterol (major sterol of baker's and brewer's yeast extracts) inhibits the growth of human breast cancer cells in vitro and the potential role of its oxidation products. Int. J. Vitam. Nutr. Res. 2003, 73, 19-23.
11. Bok, J. W.; Lermer, L.; Chilton, J.; Klingeman, H. G.; Towers, G. H. N. Antitumor sterols from the mycelia of Cordyceps sinensis. Phytochemistry 1999, 51, 891-898.
12. Togashi, H.; Mizushina, Y.; Takemura, M.; Sugawara, F.; Koshino, H.; Esumi, Y.; Uzawa, J.; Kumagai, H.; Matsukage, A.; Yoshida, S.; Sakaguchi, K. 4-Hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-α activity and the growth of human cancer cells in vitro. Biochem. Pharmacol. 1998, 56, 583-590.
13. Zaidman, B. Z.; Yassin, M.; Mahajna, J.; Wasser, S. P. Medicinal mushroom modulators of molecular targets as cancer therapeutics. Appl. Microbiol. Biotechnol. 2005, 67, 453-468.
14. Kim, D. S.; Baek, N. I.; Oh, S. R.; Jung, K. Y.; Lee, I. S.; Kim, J. H.; Lee, H. K. Anticomplementary activity of ergosterol peroxide from Naematoloma fasciculare and reassignment of NMR data. Arch. Pharm. Res. 1997, 20, 201-205.
15. Slominski, A.; Semak, I.; Zjawiony, J.; Wortsman, J.; Gandy, M. N.; Li, J. H.; Zbytek, B.; Li, W.; Tuckey, R. C. Enzymatic metabolism of ergosterol by cytochrome P450scc to biologically active 17α,24-dihydroxyergosterol. Chem. Biol. 2005, 12, 931-939.
16. Czub, J.; Baginski, M. Comparative molecular dynamics study of lipid membranes containing cholesterol and ergosterol. Biophys. J. 2006, 90, 2368-2382.
17. Lochman, J.; Mikes, V. Activation of different defence-related genes expression by ergosterol. FEBS J. 2005, 272, 470-470.
18. de Sio, F.; Laratta, B.; Giovane, A.; Quagliuolo, L.; Castaldo, D.; Servillo, L. Analysis of free and esterified ergosterol in tomato products. J. Agric. Food Chem. 2000, 48, 780-784.
19. Pasanen, A. L.; Yli-Pietila, K.; Pasanen, P.; Kalliokoski, P.; Tarhanen, J. Ergosterol content in various fungal species and biocontaminated building materials. Appl. Environ. Microbiol. 1999, 65, 138-142.
20. Sun, S. J.; Gao, Y. H.; Ling, X.; Lou, H. X. The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry. Anal. Biochem. 2005, 336, 39-45.
21. Varga, M.; Bartók, T.; Mesterházy, A. Determination of ergosterol in Fusarium-infected wheat by liquid chromatography-atmospheric pressure photoionization mass spectrometry. J. Chromatogr. A 2006, 1103, 278-283.
22. Abramson, D.; Smith, D. M. Determination of ergosterol in canola (Brassica napus L.) by liquid chromatography. J. Stored Prod. Res. 2003, 39, 185-191.
23. 2 by UV irradiation. Food Chem. 2005, 92, 541-546.
24. Lau, A. P. S.; Lee, A. K. Y.; Chan, C. K.; Fang, M. Ergosterol as a biomarker for the quantification of the fungal biomass in atmospheric aerosols. Atmos. Environ. 2006, 40, 249-259.
25. Gonzalez, A. G.; Leon, F.; Rivera, A.; Munoz, C. M.; Bermejo, J. Lanostanoid triterpenes from Ganoderma lucidum. J. Nat. Prod. 1999, 62, 1700-1701.
26. Ziegenbein, F. C.; Hanssen, H. P.; König, W. A. Secondary metabolites from Ganoderma lucidum and Spongiporus leucomallellus. Phytochemistry 2006, 67, 202-211.
27. Liu, X.; Wang, J. H.; Yuan, J. P. Pharmacological and antitumor activities of Ganoderma spores processed by top-down approaches. J. Nanosci. Nanotechnol. 2005, 5, 2001-2013.
28. Hsu, R. C.; Lin, B. H.; Chen, C. W. The study of supercritical carbon dioxide extraction for Ganoderma lucidum. Ind. Eng. Chem. Res. 2001, 40, 4478-4481.
29. Yuan, J. P.; Chen, F. Hydrolysis kinetics of astaxanthin esters and stability of astaxanthin of Haematococcus pluvialis during saponification. J. Agric. Food Chem. 1999, 47, 31-35.
30. Abidi, S. L. Capillary electrochromatography of sterols and related steryl esters derived from vegetable oils. J. Chromatogr. A 2004, 1059, 199-208.
31. Jimenez-Escrig, A.; Santos-Hidalgo, A. B.; Saura-Calixto, F. Common sources and estimated intake of plant sterols in the Spanish diet. J. Agric. Food Chem. 2006, 54, 3462-3471.
32. Kalo, P.; Kuuranne, T. Analysis of free and esterified sterols in fats and oils by flash chromatography, gas chromatography and electrospray tandem mass spectrometry. J. Chromatogr. A 2001, 935, 237-248.
33. Liu, X.; Yuan, J. P.; Chung, C. K.; Chen, X. J. Antitumor activity of the sporoderm-broken germinating spores of Ganoderma lucidum. Cancer Lett. 2002, 182, 155-161.