4-hydroxy-17-methylincisterol, an inhibitor of DNA polymerase-α activity and the growth of human cancer cells in vitro

Biochemical Pharmacology

Volumn 56, Issue 5, 1998, Pages 583-590

  Togashi, Hideaki ^a   Mizushina, Yoshiyuki ^a   Takemura, Masaharu ^b   Sugawara, Fumio ^a   Koshino, Hiroyuki ^c   Esumi, Yasuaki ^c   Uzawa, Jun ^c   Kumagai, Hiroyuki ^d   Matsukage, Akio ^e   Yoshida, Shonen ^b   Sakaguchi, Kengo ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b Res Inst Dis Mechanism Contr   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d MERCIAN CORPORATION   (Japan)

^e AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

4 Hydroxy 17 methylincisterol; DNA polymerase ; Enzyme inhibitor; Ergosterol derivative

Indexed keywords

4 HYDROXY 17 METHYLINCISTEROL; CYTOTOXIC AGENT; DNA DIRECTED DNA POLYMERASE ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CANCER; CANCER GROWTH; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; TECHNIQUE;

ANIMALS; CATTLE; CELL DIVISION; DNA NUCLEOTIDYLEXOTRANSFERASE; DNA POLYMERASE BETA; DNA POLYMERASE I; ENZYME INHIBITORS; ERGOSTEROL; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; LINEAR MODELS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0032168150     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00197-X     Document Type: Article

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