Histamine decreases myogenic tone in rat cerebral arteries by H2-receptor-mediated KV channel activation, independent of endothelium and cyclic AMP

European Journal of Pharmacology

Volumn 547, Issue 1-3, 2006, Pages 116-124

  Jarajapu, Yagna P R ^a,b   Oomen, Charlotte ^a,c   Uteshev, Victor V ^a,d   Knot, Harm J ^a,b,c,e  

^a UNIVERSITY OF FLORIDA   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

^d SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Danish MyoTechnology   (Denmark)

Author keywords

Endothelium; Histamine; KV potassium channels; Myogenic tone; Rat cerebral artery

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 2 (2 PYRIDYL)ETHYLAMINE; 4 AMINOPYRIDINE; 4,4',4'',4''' [CARBONYLBIS[IMINO 5,1,3 BENZENETRIYLBIS(CARBONYLIMINO)]]TETRAKIS(BENZENE 1,3 DISULFONIC ACID, 8 SODIUM); 9 (TETRAHYDRO 2 FURYL)ADENINE; ADENYLATE CYCLASE; ADENYLATE CYCLASE INHIBITOR; AMTHAMINE; BARIUM CHLORIDE; BRADYKININ; CYCLIC AMP; FORSKOLIN; FURA 2; GLIBENCLAMIDE; GUANYLATE CYCLASE; GUANYLATE CYCLASE INHIBITOR; HISTAMINE; HISTAMINE H1 RECEPTOR AGONIST; HISTAMINE H2 RECEPTOR; HISTAMINE H2 RECEPTOR AGONIST; HISTAMINE H3 RECEPTOR AGONIST; IBERIOTOXIN; IMETIT; NF 449; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHLORIDE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; TETRYLAMMONIUM CHLORIDE; TIOTIDINE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL TISSUE; ARTERY DIAMETER; ARTERY DILATATION; ARTERY TONE; ARTERY WALL; ARTICLE; BRAIN ARTERY; BRAIN BLOOD FLOW; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; ENZYME ACTIVATION; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

ADENINE; ADENYLATE CYCLASE; ANIMALS; BENZENESULFONATES; CALCIUM; CEREBRAL ARTERIES; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GUANYLATE CYCLASE; HISTAMINE; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; MALE; MUSCLE, SMOOTH, VASCULAR; OXADIAZOLES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; POTASSIUM CHLORIDE; QUINOXALINES; RATS; RATS, SPRAGUE-DAWLEY; THIAZOLES; VASOCONSTRICTION; VASODILATION;

EID: 33748572263     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.07.036     Document Type: Article

References (52)

1. Adeagbo A.S., and Oriowo M.A. Histamine receptor subtypes mediating hyperpolarization in the isolated, perfused rat mesenteric pre-arteriolar bed. Eur. J. Pharmacol. 347 (1998) 237-244
2. Aiello E.A., Malcolm A.T., Walsh M.P., and Cole W.C. Beta-adrenoceptor activation and PKA regulate delayed rectifier K+ channels of vascular smooth muscle cells. Am. J. Physiol. 275 (1998) H448-H459
3. Benedito S., Prieto D., and Nyborg N.C. Influence of the endothelium on histamine-induced relaxation of rat middle cerebral arteries in vitro. J. Cardiovasc. Pharmacol. 17 (1991) 90-95
4. Bonnet P., Rusch N.J., and Harder D.R. Characterization of an outward K+ current in freshly dispersed cerebral arterial muscle cells. Pflugers Arch. 418 (1991) 292-296
5. Brayden J.E., and Nelson M.T. Regulation of arterial tone by activation of calcium-dependent potassium channels. Science 256 (1992) 532-535
6. Brown R.E., Stevens D.R., and Haas H.L. The physiology of brain histamine. Prog. Neurobiol. 63 (2001) 637-672
7. Cole W.C., Clement-Chomienne O., and Aiello E.A. Regulation of 4-aminopyridine-sensitive, delayed rectifier K+ channels in vascular smooth muscle by phosphorylation. Biochem. Cell. Biol. 74 (1996) 439-447
8. Dacey Jr. R.G., and Bassett J.E. Histaminergic vasodilation of intracerebral arterioles in the rat. J. Cereb. Blood Flow Metab. 7 (1987) 327-331
9. Daut J. Inhibition of the sodium pump in guinea-pig ventricular muscle by dihydro-ouabain: effects of external potassium and sodium. J. Physiol. 339 (1983) 643-662
10. Donaldson J., and Hill S.J. Enhancement of histamine H1-receptor agonist activity by 1,4-dithiothreitol in guinea-pig cerebellum and cerebral cortex. J. Neurochem. 47 (1986) 1476-1482
11. Dux M., Schwenger N., and Messlinger K. Possible role of histamine (H1- and H2-) receptors in the regulation of meningeal blood flow. Br. J. Pharmacol. 137 (2002) 874-880
12. Ea K.L., Sercombe R., and Oudart N. Relaxation of rabbit middle cerebral arteries in vitro by H1 histaminergic agonists is inhibited by indomethacin and tranylcypromine. Fundam. Clin. Pharmacol. 2 (1988) 463-475
13. Eriks J.C., Van der G.H., Sterk G.J., and Timmerman H. Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles. J. Med. Chem. 35 (1992) 3239-3246
14. Fabbri E., Brighenti L., and Ottolenghi C. Inhibition of adenylate cyclase of catfish and rat hepatocyte membranes by 9-(tetrahydro-2-furyl)adenine (SQ 22536). J. Enzyme Inhib. 5 (1991) 87-98
15. Faraci F.M., and Heistad D.D. Regulation of the cerebral circulation: role of endothelium and potassium channels. Physiol. Rev. 78 (1998) 53-97
16. Fernandez-Fernandez J.M., Wanaverbecq N., Halley P., Caulfield M.P., and Brown D.A. Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurons. J. Physiol. 515 (1999) 631-637
17. Galvez A., Gimenez-Gllego G., Reuben J.P., Roy-Contancin L., Feigenbaum P., Kaczorowski G.J., and Garcia M.L. Purification and characterization of a unique, potent, peptidyl probe for the high conductance calcium-activated potassium channel from venom of the scorpion Buthus tamulus. J. Biol. Chem. 265 (1990) 11083-11090
18. Garbarg M., Arrang J.M., Rouleau A., Ligneau X., Tuong M.D., Schwartz J.C., and Ganellin C.R. S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist. J. Pharmacol. Exp. Ther. 263 (1992) 304-310
19. Garthwaite J., Southam E., Boulton C.L., Nielsen E.B., Schmidt K., and Mayer B. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol. Pharmacol. 48 (1995) 184-188
20. Geary G.G., Krause D.N., and Duckles S.P. Melatonin directly constricts rat cerebral arteries through modulation of potassium channels. Am. J. Physiol. 273 (1997) H1530-H1536
21. Gromada J., Hoy M., Olsen H.L., Gotfredsen C.F., Buschard K., Rorsman P., and Bokvist K. Gi2 proteins couple somatostatin receptors to low-conductance K+ channels in rat pancreatic α-cells. Pflugers Arch. 442 (2001) 19-26
22. Heatley R.V., Denburg J.A., Bayer N., and Bienenstock J. Increased plasma histamine levels in migraine patients. Clin. Allergy 12 (1982) 145-149
23. Hill S.J. Distribution, properties and functional characteristics of three classes of histamine receptor. Pharmacol. Rev. 42 (1990) 45-83
24. Hill S.J., Daum P., and Young J.M. Affinities of histamine H1-antagonists in guinea pig brain: similarity of values determined from [3H]mepyramine binding and from inhibition of a functional response. J. Neurochem. 37 (1981) 1357-1360
25. Hill S.J., Ganellin C.R., Timmerman H., Schwartz J.C., Shankley N.P., Young J.M., Schunack W., Levi R., and Haas H.L. International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol. Rev. 49 (1997) 253-278
26. 2+ signalling pathways underlying myogenic reactivity. J. Appl. Physiol. 91 (2001) 973-983
27. 3-adrenoceptor-mediated, cAMP-independent relaxations of guinea-pig gastrointeristinal smooth muscles. Naunyn-Schmiedeberg's Arch. Pharmacol. 367 (2003) 193-203
28. Hohenegger M., Waldhoer M., Beindl W., Boing B., Kreimeyer A., Nickel P., Nanoff C., and Freissmuth M. Gsalpha-selective G protein antagonists. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 346-351
29. Johnson P.C. Autoregulation of blood flow. Circ. Res. 59 (1986) 483-495
30. + channels to A1 receptors by G-proteins in rat ventricular myocytes. Am. J. Physiol. 259 (1990) H820-H826
31. + channels in rabbit myogenic cerebral arteries. Am. J. Physiol. 269 (1995) H348-H355
32. 2+] in cerebral arteries of rat by membrane potential and intravascular pressure. J. Physiol. 1998 508 (1998) 199-209
33. + channels. J. Physiol. 492 (1996) 419-430
34. Lagaud G.J., Skarsgard P.L., Laher I., and Van Breemen C. Heterogeneity of endothelium-dependent vasodilation in pressurized cerebral and small mesenteric resistance arteries of the rat. J. Pharmacol. Exp. Ther. 290 (1999) 832-839
35. Lassen L.H., Thomsen L.L., and Olesen J. Histamine induces migraine via the H1-receptor. Support for the NO hypothesis of migraine. NeuroReport 6 (1995) 1475-1479
36. Martinez A.C., Prieto D., Raposo R., Delgado J.A., Resel L., Garcia-Sacristan A., and Benedito S. Endothelium-independent relaxation induced by histamine in human dorsal penile artery. Clin. Exp. Pharmacol. Physiol. 27 (2000) 500-507
37. McCarron J.G., and Halpern W. Potassium dilates rat cerebral arteries by two independent mechanisms. Am. J. Physiol. 259 (1990) H902-H908
38. McDaniel N.L., Rembold C.M., and Murphy R.A. Cyclic nucleotide dependent relaxation in vascular smooth muscle. Can. J. Physiol. Pharmacol. 72 (1994) 1380-1385
39. Moritoki H., Hosoki E., and Ishida Y. Age-related decrease in endothelium-dependent dilator response to histamine in rat mesenteric artery. Eur. J. Pharmacol. 126 (1986) 61-67
40. Nelson M.T., and Quayle J.M. Physiological roles and properties of potassium channels in arterial smooth muscle. Am. J. Physiol. 268 (1995) C799-C822
41. Nelson M.T., Patlak J.B., Worley J.F., and Standen N.B. Calcium channels, potassium channels and voltage dependence of arterial smooth muscle tone. Am. J. Physiol. 259 (1990) C3-C18
42. Pasyk E.A., Cipris S., and Daniel E.E. A G-protein, not cyclic AMP, mediates effects of VIP on the inwardly rectifying K+ channels in endothelial cells. J. Pharmacol. Exp. Ther. 276 (1996) 690-696
43. Porter V.A., Bonev A.D., Knot H.J., Heppner T.J., Stevenson A.S., Kleppisch T., Lederer W.J., and Nelson M.T. Frequency modulation of Ca2+ sparks is involved in regulation of arterial diameter by cyclic nucleotides. Am. J. Physiol. 274 (1998) C1346-C1355
44. Quayle J.M., McCarron J.G., Brayden J.E., and Nelson M.T. Inward rectifier K+ currents in smooth muscle cells from rat resistance-sized cerebral arteries. Am. J. Physiol. 265 (1993) C1363-C1370
45. + currents in smooth muscle cells from cerebral arteries. Am. J. Physiol. 267 (1994) C1589-C1597
46. Rosenblum W.I., Nelson G.H., and Weinbrecht P. Histamine elicits competing endothelium-dependent constriction and endothelium-independent dilation in vivo in mouse cerebral arterioles. Stroke 21 (1990) 305-309
47. x and competitive drug antagonism. Br. J. Pharmacol. 4 (1949) 277-280
48. Schmetterer L., Wolzt M., Graselli U., Findl O., Strenn K., Simak S., Kastner J., Eichler H.G., and Singer E.A. Nitric oxide synthase inhibition in the histamine headache model 16. Cephalalgia 17 (1997) 175-182
49. Schubert R., and Nelson M.T. Protein kinases: tuners of the BKCa channel in smooth muscle. Trends Pharmacol. Sci. 22 (2001) 505-512
50. 2+ dynamics in response to choline-mediated excitation in histaminergic tuberomammillary neurons. Neuroscience 134 (2005) 133-143
51. Yellin T.O., Buck S.H., Gilman D.J., Jones D.F., and Wardleworth J.M. ICI 125,211: a new gastric antisecretory agent acting on histamine H2-receptors. Life Sci. 25 (1979) 2001-2009
52. + channel openers in cerebral arteries from diabetic rats. Circ. Res. 81 (1997) 996-1004