In vitro and in vivo assessment of humic acid as an aflatoxin binder in broiler chickens

Poultry Science

Volumn 85, Issue 9, 2006, Pages 1576-1583

  Jansen Van Rensburg, C ^a   Van Rensburg, C E J ^a   Van Ryssen, J B J ^a   Casey, N H ^a   Rottinghaus, G E ^b  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Aflatoxin binder; Broiler; Humic acid; Oxihumate

Indexed keywords

AVES; GALLUS GALLUS;

EID: 33748565917     PISSN: 00325791     EISSN: 15253171     Source Type: Journal    
DOI: 10.1093/ps/85.9.1576     Document Type: Article

References (51)

1. Abo-Norag, M., T. S. Edrington, L. F. Kubena, R. B. Harvey, and T. D. Phillips. 1995. Influence of a hydrated sodium calcium aluminosilicate and virginiamycin on aflatoxicosis in broiler chicks. Poult. Sci. 74:626-632.
2. 1 on liver microsomal enzymes in different strains of chickens. Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. 118:185-189.
3. Aravind, K. L., V. S. Patil, G. Devegowda, B. Umakantha, and S. P. Ganpule. 2003. Efficacy of esterified glucomannan to counteract mycotoxicosis in naturally contaminated feed on performance and serum biochemical and hematological parameters in broilers. Poult. Sci. 82:571-576.
4. Bailey, R. H., L. F. Kubena, R. B. Harvey, S. A. Buckley, and G. E. Rottinghaus. 1998. Efficacy of various inorganic sorbents to reduce the toxicity of aflatoxin and T-2 toxin in broiler chicks. Poult. Sci. 77:1623-1630.
5. Bergh, J. J., I. J. Cronjé, J. Dekker, T. G. Dekker, L. M. Gerritsma, and L. J. Mienie. 1997. Non-catalytic oxidation of water-slurried coal with oxygen: Identification of fulvic acids and acute toxicity. Fuel 76:149-154.
6. Clifford, J. I., and K. R. Rees. 1967. The interaction of aflatoxins with purines and purine nucleosides. Biochem. J. 103:467-471.
7. 1. Pages 89-101 in The Toxicology of Aflatoxins: Human Health, Veterinary, and Agricultural Significance. D. L. Eaton and J. D. Groopman, ed. Academic Press Inc, San Diego, CA.
8. Cozzi, R., M. Nicolai, P. Perticone, R. De Salvia, and F. Spuntarelli. 1993. Desmutagenic activity of natural humic acids: Inhibition of mitomycin C and maleic hydrazide mutagenicity. Mutat. Res. 299:37-44.
9. Dale, N. 1998. Mycotoxin binders: It's time for real science. Poult. Dig. 57:38-39.
10. 1. Vet. Hum. Toxicol. 22:388-389.
11. Diaz, G. J., A. Cortés, and L. Roldán. 2005. Evaluation of the efficacy of four feed additives against the adverse effects of T-2 toxin in growing broiler chickens. J. Appl. Poult. Res. 14:226-231.
12. Doyle, M. P., R. S. Applebaum, R. E. Brackett, and E. H. Marth. 1982. Physical, chemical and biological degradation of mycotoxins in foods and agricultural commodities. J. Food Prot. 45:946-971.
13. Dvorska, J. E., P. F. Surai, B. K. Speake, and N. H. C. Sparks. 2003. Protective effect of modified glucomannans against aurofusarin-induced changes in quail egg and embryo. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 135:337-343.
14. Elfarissi, F., and E. Pefferkorn. 2000. Kaolinite/humic acid interaction in the presence of aluminium ion. Colloids Surf. A 168:1-12.
15. Fein, J. B., J. Boily, K. Güçlü, and E. Kaulbach. 1999. Experimental study of humic acid adsorption onto bacteria and Al-oxide mineral surfaces. Chem. Geol. 162:33-45.
16. Huff, W. E., and J. A. Doerr. 1981. Synergism between aflatoxin and ochratoxin A in broiler chickens. Poult. Sci. 60:550-555.
17. Huff, W. E., L. F. Kubena, R. B. Harvey, W. M. Hagler Jr., S. P. Swanson, T. D. Phillips, and C. R. Creger. 1986. Individual and combined effects of aflatoxin and deoxynivalenol (DON, Vomitoxin) in broiler chickens. Poult. Sci. 65:1291-1298.
18. Huff, W. E., L. F. Kubena, R. B. Harvey, and T. D. Phillips. 1992. Efficacy of hydrated sodium calcium aluminosilicate to reduce the individual and combined toxicity of aflatoxin and ochratoxin A. Poult. Sci. 71:64-69.
19. Huwig, A., S. Freimund, O. Käppeli, and H. Dutler. 2001. Mycotoxin detoxification of animal feed by different adsorbents. Toxicol. Lett. 122:179-188.
20. Karaman, M., H. Basmacioglu, M. Ortatatli, and H. Oguz. 2005. Evaluation of the detoxifying effect of yeast glucomannan on aflatoxicosis in broilers as assessed by gross examination and histopathology. Br. Poult. Sci. 46:394-400.
21. 1 on chicken chondrocytes in culture. Avian Dis. 38:11-15.
22. Kinniburgh, D. G. 1986. General purpose adsorption isotherms. Environ. Sci. Technol. 20:895-904.
23. Kollist-Siigur, K., T. Nielsen, C. Grøn, P. E. Hansen, C. Helweg, K. E. Jonassen, O. Jørgensen, and U. Kirso. 2001. Sorpsion of polycyclic aromatic compounds to humic and fulvic acid HPLC column materials. J. Environ. Qual. 30:526-537.
24. Kubena, L. F., R. B. Harvey, W. E. Huff, D. E. Corner, T. D. Phillips, and G. E. Rottinghaus. 1990a. Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and T-2 toxin. Poult. Sci. 69:1078-1086.
25. Kubena, L. F., R. B. Harvey, T. D. Phillips, D. E. Corrier, and W. E. Huff. 1990b. Diminution of aflatoxicosis in growing chickens by dietary addition of a hydrated sodium calcium aluminosilicate. Poult. Sci. 69:727-735.
26. Kumagai, S. 1989. Intestinal absorption and excretion of aflatoxin in rats. Toxicol. Appl. Pharmacol. 97:88-97.
27. Langmuir, I. 1916. The constitution and fundamental properties of solids and liquids. J. Am. Chem. Soc. 38:2221-2294.
28. Ledoux, D. R., G. E. Rottinghaus, A. J. Bermudez, and M. Alonso-Debolt. 1999. Efficacy of a hydrated sodium calcium aluminosilicate to ameliorate the toxic effects of aflatoxin in broiler chicks. Poult. Sci. 78:204-210.
29. Madronová, L., J. Kozler, J. Cezíková, J. Novák, and P. Janoš. 2001. Humic acids from coal of the North-Bohemia coal field. III. Metal-binding properties of humic acids-measurements in a column arrangement. React. Func. Polym. 47:119-123.
30. Marquardt, R. R. 1996. Effects of molds and their toxins on livestock performance: A western Canadian perspective. Anim. Feed Sci. Technol. 58:77-89.
31. Miazzo, R., C. A. R. Rosa, E. C. Q. Carvalho, C. Magnoli, S. M. Chiacchiera, G. Palacio, M. Saenz, A. Kikot, E. Basaldella, and A. Dalcero. 2000. Efficacy of synthetic zeolite to reduce the toxicity of aflatoxin in broiler chicks. Poult. Sci. 79:1-6.
32. Nanny, M. A., and J. P. Maza. 2001. Noncovalent interactions between monoaromatic compounds and dissolved humic acids: A deuterium NMR T1 relaxation study. Environ. Sci. Technol. 35:379-384.
33. National Research Council. 1994. Nutrient Requirements of Poultry. 9th rev. ed. Natl. Acad. Press, Washington, DC.
34. Nègre, M., H. R. Schulten, M. Gennari, and D. Vindrola. 2001. Interaction of imidazolinone herbicides with soil humic acids. Experimental results and molecular modeling. J. Environ. Sci. Health B 36:107-125.
35. Peers, F., X. Bosch, and J. Kaldor. 1987. Aflatoxin exposure, hepatitis B virus infection and liver cancer in Swaziland. Int. J. Cancer 39:545-553.
36. Raju, M. V. L. N., and G. Devegowda. 2000. Influence of esterified-glucomannan on performance and organ morphology, serum biochemistry and haematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin and T-2 toxin). Br. Poult. Sci. 41:640-650.
37. Ramos, A. J., J. Fink-Gremmels, and E. Hernández. 1996a. Prevention of toxic effects of mycotoxins by means of nonnutritive adsorbent compounds. J. Food Prot. 59:631-641.
38. Ramos, A. J., and E. Hernández. 1996. In vitro aflatoxin adsorption by means of a montmorillonite silicate. A study of adsorption isotherms. Anim. Feed Sci. Technol. 62:263-269.
39. Ramos, A. J., E. Hernández, M. Plá-Delfina, and M. Merino. 1996b. Intestinal absorption of zearalenone and in vitro study of non-nutritive sorbent materials. Int. J. Pharm. 128:129-137.
40. Rosa, C. A. R., R. Miazzo, C. Magnoli, M. Salvano, S. M. Chiacchiera, S. Ferrero, M. Saenz, E. C. Q. Carvalho, and A. Dalcero. 2001. Evaluation of the efficacy of bentonite from the south of Argentina to ameliorate the toxic effects of aflatoxin in broilers. Poult. Sci. 80:139-144.
41. Samuels, M. L. 1989. Statistics for the Life Sciences. Collier MacMillan Publishers, London, UK.
42. SAS Institute. 1994. SAS User's Guide: Statistics. Version. 6. SAS Institute Inc. Cary, NC.
43. Sato, T., Y. Ose, H. Nagase, and K. Hayase. 1987. Adsorption of mutagens by humic acid. Sci. Total Environ. 62:305-310.
44. Shotwell, O. L., C. W. Hesseltine, R. D. Stubblefield, and W. G. Sorenson. 1966. Production of aflatoxin on rice. Appl. Microbiol. 14:425-428.
45. Stanley, V. G., R. Ojo, S. Woldesenbet, D. H. Hutchinson, and L. F. Kubena. 1993. The use of Saccharomyces cerevisiae to suppress the effects of aflatoxicosis in broiler chicks. Poult. Sci. 72:1867-1872.
46. Technicon RA Systems. 1994. Methods Manual. Bayer Corp., Tarrytown, NY.
47. Tung, H. T., R. D. Wyatt, P. Thaxton, and P. B. Hamilton. 1975. Concentrations of serum proteins during aflatoxicosis. Toxicol. Appl. Pharmacol. 34:320-326.
48. Van Rensburg, S. J., P. Cook-Mozaffari, and D. J. Van Schalkwyk. 1985. Hepatocellular carcinoma and dietary aflatoxin in Mozambique and Transkei. Br. J. Cancer 51:713-726.
49. Verma, R. J., and P. J. Raval. 1991. Cytotoxicity of aflatoxin on red blood corpuscles. Bull. Environ. Contam. Toxicol. 47:428-433.
50. 1-14C in rats. Cancer Res. 27:1729-1736.
51. 1 toxicity in broilers. Wien Tierarztl. Monatsschr. 85:43-48.