-
1
-
-
0018750365
-
Diabetes and glucose tolerance as risk factors for cardiovascular disease: The Framingham Study
-
Kannel WB, McGee DL. Diabetes and glucose tolerance as risk factors for cardiovascular disease: The Framingham Study. Diabetes Care 1979; 2:120-126. This is a landmark early study from Framingham. It is perhaps the first population-based study showing the link between DM and CAD.
-
(1979)
Diabetes Care
, vol.2
, pp. 120-126
-
-
Kannel, W.B.1
McGee, D.L.2
-
2
-
-
33748561340
-
Glucose tolerance and the risk of cardiovascular disease: The Zutphen Study
-
Feskens EJ, Kromhout D. Glucose tolerance and the risk of cardiovascular disease: The Zutphen Study. J Clin Epidemiol 2001; 54:869-876.
-
(2001)
J Clin Epidemiol
, vol.54
, pp. 869-876
-
-
Feskens, E.J.1
Kromhout, D.2
-
3
-
-
0027406191
-
Diabetes, other risk factors, and 12-year cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial
-
Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-year cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993; 16:434-444. This is one of the first modern-era epidemiologic studies of the strong association between DM and CAD. It explores inter-relationships between DM and associated risk factors for CAD.
-
(1993)
Diabetes Care
, vol.16
, pp. 434-444
-
-
Stamler, J.1
Vaccaro, O.2
Neaton, J.D.3
Wentworth, D.4
-
4
-
-
0034912564
-
The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women
-
Hu FB, Stampfer MJ, Solomon CG, Liu S, Willett WC, Speizer FE, et al. The impact of diabetes mellitus on mortality from all causes and coronary heart disease in women. Arch Int Med 2001; 161:1717-1723. This is an epidemiologic study focusing on women with DM. It is one of several documenting that women with DM have a poorer cardiovascular prognosis than men.
-
(2001)
Arch Int Med
, vol.161
, pp. 1717-1723
-
-
Hu, F.B.1
Stampfer, M.J.2
Solomon, C.G.3
Liu, S.4
Willett, W.C.5
Speizer, F.E.6
-
5
-
-
0032560807
-
Mortality from coronary heart disease in subjects with type 2 diabetes and in non-diabetic subjects with and without prior myocardial infarction
-
Haffner SM, Lehto S, Ronnemaa T, Pyorala K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in non-diabetic subjects with and without prior myocardial infarction. N Engl J Med 1998; 339:229-234. This is a large-scale epidemiologic study that provides perhaps the most definitive information about excess CAD risk in type 2 DM. The study is extremely well controlled. It provides key data about the interaction between type 2 DM and prior myocardial infarction.
-
(1998)
N Engl J Med
, vol.339
, pp. 229-234
-
-
Haffner, S.M.1
Lehto, S.2
Ronnemaa, T.3
Pyorala, K.4
Laakso, M.5
-
6
-
-
0034730110
-
Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q wave myocardial infarction: Results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry
-
Malmberg K, Yusuf S, Gerstein HC, Brown J, Zhao F, Hunt D, et al. Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry. Circulation 2000; 102:1014-1019.
-
(2000)
Circulation
, vol.102
, pp. 1014-1019
-
-
Malmberg, K.1
Yusuf, S.2
Gerstein, H.C.3
Brown, J.4
Zhao, F.5
Hunt, D.6
-
7
-
-
0027370468
-
Influence of diabetes on mortality in acute myocardial infarction; data from the GISSI-2 study
-
Zuanetti G, Latini R, Maggioni AP, Santoro L, Franzosi MG. Influence of diabetes on mortality in acute myocardial infarction; data from the GISSI-2 study. J Am Coll Cardiol 1993; 22:1788-1794.
-
(1993)
J Am Coll Cardiol
, vol.22
, pp. 1788-1794
-
-
Zuanetti, G.1
Latini, R.2
Maggioni, A.P.3
Santoro, L.4
Franzosi, M.G.5
-
8
-
-
0033867999
-
Diabetes mellitus in cardiogenic shock complicating acute myocardial infarction: A report from the SHOCK Trial Registry
-
Shindler DM, Palmeri ST, Antonelli TA, Sleeper LA, Boland J, Cocke TP, Hochman JS. Diabetes mellitus in cardiogenic shock complicating acute myocardial infarction: a report from the SHOCK Trial Registry. J Am Coll Cardiol 2000; 36 (Suppl A):1097-1103.
-
(2000)
J Am Coll Cardiol
, vol.36
, Issue.SUPPL. A
, pp. 1097-1103
-
-
Shindler, D.M.1
Palmeri, S.T.2
Antonelli, T.A.3
Sleeper, L.A.4
Boland, J.5
Cocke, T.P.6
Hochman, J.S.7
-
9
-
-
0037903801
-
Impact of diabetes on mortality after the first myocardial infarction
-
The FINMONICA Myocardial Infarction Register Study Group
-
Miettinen H, Lehto S, Salomaa V, Mahonen M, Niemela M, Haffner SM, et al. Impact of diabetes on mortality after the first myocardial infarction. The FINMONICA Myocardial Infarction Register Study Group. Diabetes Care 1998; 21:69-75.
-
(1998)
Diabetes Care
, vol.21
, pp. 69-75
-
-
Miettinen, H.1
Lehto, S.2
Salomaa, V.3
Mahonen, M.4
Niemela, M.5
Haffner, S.M.6
-
10
-
-
0028069788
-
NIDDM and is metabolic control predict coronary heart disease in elderly subjects
-
Kuusisto J, Mykannen L, Pyorala K, Laakso M. NIDDM and is metabolic control predict coronary heart disease in elderly subjects. Diabetes 1994; 43:960-967.
-
(1994)
Diabetes
, vol.43
, pp. 960-967
-
-
Kuusisto, J.1
Mykannen, L.2
Pyorala, K.3
Laakso, M.4
-
11
-
-
0034641568
-
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
-
Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 2000; 321:405-412. An important study relating glycemia to cardiovascular and other DM complications. It shows that glycemia has a complex relationship with risk.
-
(2000)
BMJ
, vol.321
, pp. 405-412
-
-
Stratton, I.M.1
Adler, A.I.2
Neil, H.A.3
Matthews, D.R.4
Manley, S.E.5
Cull, C.A.6
-
12
-
-
0033592101
-
Glucose tolerance and mortality: Comparison of WHO and American Diabetes Association diagnostic criteria: European Diabetes Epidemiology Group
-
DECODE Study Group. Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria: European Diabetes Epidemiology Group. Lancet 1999; 354:617-621.
-
(1999)
Lancet
, vol.354
, pp. 617-621
-
-
-
13
-
-
0025367559
-
Cardiovascular risk factors in confirmed pre-diabetic individuals: Does the clock for coronary heart disease start ticking before the onset of clinical diabetes?
-
Haffner SM, Stern MP, Hazuda HP, Mitchell BD, Patterson JK. Cardiovascular risk factors in confirmed pre-diabetic individuals: does the clock for coronary heart disease start ticking before the onset of clinical diabetes? JAMA 1990; 263:2893-2898. This is an important study that follows the course of patients with IR. Its results suggest that CAD develops before overt type 2 DM appears.
-
(1990)
JAMA
, vol.263
, pp. 2893-2898
-
-
Haffner, S.M.1
Stern, M.P.2
Hazuda, H.P.3
Mitchell, B.D.4
Patterson, J.K.5
-
14
-
-
0037417939
-
Burgeoning dilemmas in the management of diabetes and cardiovascular disease
-
Sobel BE, Frye R, Detre KM. Burgeoning dilemmas in the management of diabetes and cardiovascular disease. Circulation 2003; 107:636-650.
-
(2003)
Circulation
, vol.107
, pp. 636-650
-
-
Sobel, B.E.1
Frye, R.2
Detre, K.M.3
-
15
-
-
0141835015
-
Insulin resistance, inflammation, and the prediabetic state
-
Haffner SM. Insulin resistance, inflammation, and the prediabetic state. Am J Cardiol 2003; 92 (Suppl 1):18-26.
-
(2003)
Am J Cardiol
, vol.92
, Issue.1 SUPPL.
, pp. 18-26
-
-
Haffner, S.M.1
-
16
-
-
0021813187
-
Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
-
Matthews DR, Hosker JP, Rudenski AS, Naylor GA, Treacher DF, Turner RL. Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28:412-419.
-
(1985)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, G.A.4
Treacher, D.F.5
Turner, R.L.6
-
17
-
-
0343185923
-
Insulin-resistant prediabetic subjects have more atherogenic risk factors then insulin-sensitive prediabetic subjects: Implications for preventing coronary heart disease during the prediabetic state
-
Haffner SM, Mykkanen L, Festa A, Burke JP, Stern MP. Insulin-resistant prediabetic subjects have more atherogenic risk factors then insulin-sensitive prediabetic subjects: implications for preventing coronary heart disease during the prediabetic state. Circulation 2000; 101:975-980.
-
(2000)
Circulation
, vol.101
, pp. 975-980
-
-
Haffner, S.M.1
Mykkanen, L.2
Festa, A.3
Burke, J.P.4
Stern, M.P.5
-
18
-
-
0025166464
-
Cardiovascular disease risk factors prior to the diagnosis of impaired glucose tolerance and non-insulin-dependent diabetes mellitus in a community of older adults
-
McPhillips JB, Barrett-Conner E, Wingard DL. Cardiovascular disease risk factors prior to the diagnosis of impaired glucose tolerance and non-insulin-dependent diabetes mellitus in a community of older adults. Am J Epidemiol 1990; 131:443-453.
-
(1990)
Am J Epidemiol
, vol.131
, pp. 443-453
-
-
McPhillips, J.B.1
Barrett-Conner, E.2
Wingard, D.L.3
-
19
-
-
0027319430
-
Cardiovascular risk factors as predictors of type 2 (non-insulin- dependent) diabetes mellitus in elderly subjects
-
Mykkanen L, Kuusisto J, Pyorala K, Laakso M. Cardiovascular risk factors as predictors of type 2 (non-insulin-dependent) diabetes mellitus in elderly subjects. Diabetologia 1993; 36:553-559.
-
(1993)
Diabetologia
, vol.36
, pp. 553-559
-
-
Mykkanen, L.1
Kuusisto, J.2
Pyorala, K.3
Laakso, M.4
-
20
-
-
0032539895
-
Insulin and risk of cardiovascular disease: A meta-analysis
-
Ruige JB, Assendelft WJJ, Dekker JM, Kostense PJ, Heine RJ, Bouter LM. Insulin and risk of cardiovascular disease: a meta-analysis. Circulation 1998; 97:996-1001.
-
(1998)
Circulation
, vol.97
, pp. 996-1001
-
-
Ruige, J.B.1
Assendelft, W.J.J.2
Dekker, J.M.3
Kostense, P.J.4
Heine, R.J.5
Bouter, L.M.6
-
21
-
-
0026728956
-
Hyperinsulinemia is not a major coronary risk factor in elderly men: The study of men born in 1913
-
Welin L, Eriksson H, Larsson B, Ohlson L-O, Svardsudd K, Tibblin G. Hyperinsulinemia is not a major coronary risk factor in elderly men: the study of men born in 1913. Diabetologia 1992; 35:766-770.
-
(1992)
Diabetologia
, vol.35
, pp. 766-770
-
-
Welin, L.1
Eriksson, H.2
Larsson, B.3
Ohlson, L.-O.4
Svardsudd, K.5
Tibblin, G.6
-
22
-
-
0028139059
-
Hyperinsulinemia does not increase the risk of fatal cardiovascular disease in elderly men or women without diabetes: The Rancho Bernardo Study, 1984-1991
-
Ferrara A, Barrett-Conner EL, Edelstein SL. Hyperinsulinemia does not increase the risk of fatal cardiovascular disease in elderly men or women without diabetes: The Rancho Bernardo Study, 1984-1991. Am J Epidemiol 1994; 140:857-869. This study was performed in the Rancho Bernardo population and is one of several with a similar theme. It argues that hyperinsulinemia per se is not a major cardiovascular risk factor in the elderly.
-
(1994)
Am J Epidemiol
, vol.140
, pp. 857-869
-
-
Ferrara, A.1
Barrett-Conner, E.L.2
Edelstein, S.L.3
-
23
-
-
0028273371
-
Insulin as a predictor of coronary heart disease: Interaction with apolipoprotein E phenotype: A report from the Multiple Risk Factor Intervention Trial
-
Orchard TJ, Eichner J, Kuller LH, Becker DJ, McCallum LM, Grandits GA. Insulin as a predictor of coronary heart disease: interaction with apolipoprotein E phenotype: a report from the Multiple Risk Factor Intervention Trial. Ann Epidemiol 1994; 4:40-45.
-
(1994)
Ann Epidemiol
, vol.4
, pp. 40-45
-
-
Orchard, T.J.1
Eichner, J.2
Kuller, L.H.3
Becker, D.J.4
McCallum, L.M.5
Grandits, G.A.6
-
24
-
-
0022295514
-
Coronary heart disease mortality in relation with diabetes, blood glucose and plasma insulin levels: The Paris Prospective Study, ten years later
-
Eschwege E, Richard JL, Thibult N, Ducimetiere P, Warnet JM, Claude JR, Rosselin GE. Coronary heart disease mortality in relation with diabetes, blood glucose and plasma insulin levels: The Paris Prospective Study, ten years later. Horm Metab Res Suppl 1985; 15:41-46.
-
(1985)
Horm Metab Res Suppl
, vol.15
, pp. 41-46
-
-
Eschwege, E.1
Richard, J.L.2
Thibult, N.3
Ducimetiere, P.4
Warnet, J.M.5
Claude, J.R.6
Rosselin, G.E.7
-
25
-
-
0022330896
-
Plasma insulin as coronary heart disease risk factor: Relationship to other risk factors and predictive value during 91/2-year follow-up of the Helsinki Policemen Study population
-
Pyorala K, Savolainen E, Kaukola S, Haapakoski J. Plasma insulin as coronary heart disease risk factor: relationship to other risk factors and predictive value during 91/2-year follow-up of the Helsinki Policemen Study population. Acta Med Scand 1985; 701 (Suppl):38-52.
-
(1985)
Acta Med Scand
, vol.701
, Issue.SUPPL.
, pp. 38-52
-
-
Pyorala, K.1
Savolainen, E.2
Kaukola, S.3
Haapakoski, J.4
-
26
-
-
0345698971
-
Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: The 22 year follow-up results of the Helsinki Policemen Study
-
Pyorala M, Miettinen H, Laakso M, Pyorala K. Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: the 22 year follow-up results of the Helsinki Policemen Study. Circulation 1998; 98:398-404. This is a large study that had very long follow-up period. It established that hyperinsulinemia is a risk factor for CAD in middle-aged men. The long follow-up qualifies this as a landmark study.
-
(1998)
Circulation
, vol.98
, pp. 398-404
-
-
Pyorala, M.1
Miettinen, H.2
Laakso, M.3
Pyorala, K.4
-
27
-
-
0032562946
-
Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease
-
Lamarche B, Tchernof A, Mauriege P, Cantin B, Dagenais GR, Lupien PJ, Despres J-P. Fasting insulin and apolipoprotein B levels and low-density lipoprotein particle size as risk factors for ischemic heart disease. JAMA 1998; 279:1955-1961.
-
(1998)
JAMA
, vol.279
, pp. 1955-1961
-
-
Lamarche, B.1
Tchernof, A.2
Mauriege, P.3
Cantin, B.4
Dagenais, G.R.5
Lupien, P.J.6
Despres, J.-P.7
-
28
-
-
0036230414
-
Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes mellitus: The Insulin Resistance Atherosclerosis Study (IRAS)
-
Festa A, D'Agostino R, Tracy RP, Haffner SM. Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes mellitus: The Insulin Resistance Atherosclerosis Study (IRAS). Diabetes 2002; 51:1131-1137.
-
(2002)
Diabetes
, vol.51
, pp. 1131-1137
-
-
Festa, A.1
D'Agostino, R.2
Tracy, R.P.3
Haffner, S.M.4
-
29
-
-
0000730344
-
Executive summary of the third report of the National Cholesterol Education Program (NCEP)
-
Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Executive summary of the third report of the National Cholesterol Education Program (NCEP). JAMA 2001; 285:2486-2497.
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
30
-
-
0031710787
-
Prevalence of insulin resistance in metabolic disorders: The Bruneck Study
-
Bonora E, Kiechl S, Willeit J, Oberhollenzer F, Egger G, Targher G, et al. Prevalence of insulin resistance in metabolic disorders: The Bruneck Study. Diabetes 1998; 47:1643-1649.
-
(1998)
Diabetes
, vol.47
, pp. 1643-1649
-
-
Bonora, E.1
Kiechl, S.2
Willeit, J.3
Oberhollenzer, F.4
Egger, G.5
Targher, G.6
-
31
-
-
0037116641
-
Prevalence of the metabolic syndrome among US adults: Findings from the Third National Health and Nutrition Examination Survey
-
Ford ES, Giles WH, Dietz WH. Prevalence of the metabolic syndrome among US adults: findings from the Third National Health and Nutrition Examination Survey. JAMA 2002; 287:356-359. This is a key study of the epidemiology of the MS. It demonstrates its remarkably high prevalence in the United States.
-
(2002)
JAMA
, vol.287
, pp. 356-359
-
-
Ford, E.S.1
Giles, W.H.2
Dietz, W.H.3
-
32
-
-
0029862973
-
Hyperinsulinemia as an independent risk factor for ischemic heart disease
-
Despres JP, Lamarche B, Mauriege P, Cantin B, Dagenais GR, Moorjani S, Lupien PJ. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 1996; 334:952-957.
-
(1996)
N Engl J Med
, vol.334
, pp. 952-957
-
-
Despres, J.P.1
Lamarche, B.2
Mauriege, P.3
Cantin, B.4
Dagenais, G.R.5
Moorjani, S.6
Lupien, P.J.7
-
33
-
-
0035197163
-
Connections between obesity and dyslipidemia
-
Denke MA. Connections between obesity and dyslipidemia. Curr Opin Lipidol 2001; 12:625-628.
-
(2001)
Curr Opin Lipidol
, vol.12
, pp. 625-628
-
-
Denke, M.A.1
-
34
-
-
0346962890
-
The metabolic syndrome and risk of major coronary events in the Scandinavian Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)
-
Girman CJ, Rhodes T, Mercuri M, Pyorala K, Kjekshus J, Pedersen TR, et al., 4S Group and the AFCAPS/TexCAPS Research Group. The metabolic syndrome and risk of major coronary events in the Scandinavian Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). Am J Cardiol 2004; 93:136-141. This paper combines data from two large epidemiologic studies. It relates the MS to risk of coronary events. The data document the high risk of CAD complications in patients with the MS.
-
(2004)
Am J Cardiol
, vol.93
, pp. 136-141
-
-
Girman, C.J.1
Rhodes, T.2
Mercuri, M.3
Pyorala, K.4
Kjekshus, J.5
Pedersen, T.R.6
-
35
-
-
0346962893
-
Effect of increasing metabolic syndrome score on atherosclerotic risk profile and coronary artery disease angiographic severity
-
Solymoss BC, Bourassa MG, Campeau L, Aniderman A, Marcil M, Lesperance J, et al. Effect of increasing metabolic syndrome score on atherosclerotic risk profile and coronary artery disease angiographic severity. Am J Cardiol 2004; 93:19-164.
-
(2004)
Am J Cardiol
, vol.93
, pp. 19-164
-
-
Solymoss, B.C.1
Bourassa, M.G.2
Campeau, L.3
Aniderman, A.4
Marcil, M.5
Lesperance, J.6
-
36
-
-
10744224403
-
Metabolic syndrome modifies the cardiovascular risk associated with angiographic coronary artery disease in women
-
Marroquin OC, Kip KE, Kelley DE, Johnson D, Shaw LJ, Merz NB, et al. Metabolic syndrome modifies the cardiovascular risk associated with angiographic coronary artery disease in women. Circulation 2004; 109:714-721.
-
(2004)
Circulation
, vol.109
, pp. 714-721
-
-
Marroquin, O.C.1
Kip, K.E.2
Kelley, D.E.3
Johnson, D.4
Shaw, L.J.5
Merz, N.B.6
-
37
-
-
0026793446
-
Role of glucose and insulin resistance in development of type 2 diabetes mellitus: Results from a 25-year follow-up study
-
Martin BC, Warram JH, Krolewski AS, Bergman RN, Soeldner JS, Kahn CR. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results from a 25-year follow-up study. Lancet 1992; 340:925-929.
-
(1992)
Lancet
, vol.340
, pp. 925-929
-
-
Martin, B.C.1
Warram, J.H.2
Krolewski, A.S.3
Bergman, R.N.4
Soeldner, J.S.5
Kahn, C.R.6
-
38
-
-
0029930899
-
Dysglycemia and the risk of cardiovascular disease
-
Gerstein HC, Yusuf S. Dysglycemia and the risk of cardiovascular disease. Lancet 1996; 347:949-950.
-
(1996)
Lancet
, vol.347
, pp. 949-950
-
-
Gerstein, H.C.1
Yusuf, S.2
-
39
-
-
0038642367
-
Diagnosis, prevention, and intervention for the metabolic syndrome
-
Scott CL. Diagnosis, prevention, and intervention for the metabolic syndrome. Am J Cardiol 2003; 92 (Suppl 1):35-42.
-
(2003)
Am J Cardiol
, vol.92
, Issue.1 SUPPL.
, pp. 35-42
-
-
Scott, C.L.1
-
40
-
-
0035948631
-
Albuminuria and the risk of cardiovascular events, death, and heart failure in diabetic and non-diabetic individuals
-
Gerstein HC, Mann JF, Yi Q, Zinman B, Dinneen SF, Hoogwerf B, et al. Albuminuria and the risk of cardiovascular events, death, and heart failure in diabetic and non-diabetic individuals. JAMA 2001; 286:421-426.
-
(2001)
JAMA
, vol.286
, pp. 421-426
-
-
Gerstein, H.C.1
Mann, J.F.2
Yi, Q.3
Zinman, B.4
Dinneen, S.F.5
Hoogwerf, B.6
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