Percutaneous optical imaging system to track reporter gene expression from vasculatures in vivo

Journal of Biomedical Optics

Volumn 11, Issue 3, 2006, Pages

  Kar, S ^a,b   Kumar, A ^a   Gao, F ^a   Qiu, B ^a   Zhan, X ^a   Yang, X ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Biomedical Engineering ^*  (United States)

Author keywords

Cardiovascular disease; Gene; Gene therapy; Green fluorescent protein; Optical imaging

Indexed keywords

ANIMAL; ARTICLE; COMPUTER ASSISTED DIAGNOSIS; CYTOLOGY; EQUIPMENT; EQUIPMENT DESIGN; EVALUATION; FEMORAL ARTERY; FIBER OPTICS; FLUORESCENCE MICROSCOPY; GENE EXPRESSION PROFILING; IN VITRO STUDY; INSTRUMENTATION; METABOLISM; METHODOLOGY; PHYSIOLOGY; REPORTER GENE; SWINE;

ANIMALS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FEMORAL ARTERY; FIBER OPTICS; GENE EXPRESSION PROFILING; GENES, REPORTER; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MICROSCOPY, FLUORESCENCE; SWINE;

GENES; IMAGING SYSTEMS; PROBES; PROTEINS;

CARDIOVASCULAR DISEASE; GENE THERAPY; GREEN FLUORESCENT PROTEIN; OPTICAL IMAGING;

OPTICAL SYSTEMS;

SUS SCROFA;

EID: 33748450762     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.220955     Document Type: Article

References (13)

1. E. Nabel, "Gene therapy for cardiovascular disease", Circulation 91, 541-548 (1995).
2. M. Gruchala, H. Roy, S. Bhardwaj, and S. Yla-Herttuala, "Gene therapy for cardiovascular diseases", Curr. Pharmaceut. Design 10, 407-423 (2004). (Pubitemid 38159871)
3. R. Weissleder and U. Mahmood, "Molecular imaging", Radiology 219, 316-333 (2001). (Pubitemid 32336342)
4. X. Yang, E. Atalar, D. Li, J. Serfaty, D. Wang, A. Kumar, and L. Cheng, "Magnetic resonance imaging permits in vivo monitoring of catheter-based vascular gene delivery", Circulation 104, 1588-1590 (2001). (Pubitemid 32947517)
5. X. Yang, H. Liu, D. Li, Z. Zhou, W. Jung, A. Deans, Y. Cui, and L. Cheng, "Digital optical imaging of green fluorescent proteins for tracking vascular gene expression: Feasibility study in rabbit and human cell models", Radiology 219, 171-175 (2001). (Pubitemid 32234070)
6. H. Chen, J. Zhen, A. Kumar, H. Hammond, L. Cheng, and X. Yang, "Detection of dual gene expression in arteries using an optical imaging method", J. Biomed. Opt. 9(6), 1223-1229 (2004). (Pubitemid 40168137)
7. A. Kumar, H. Chen, E. Long, and X. Yang, "Design of minimally invasive optical imaging probe for tracking vascular gene expression: A monte carlo simulation analysis (abstract)", 2002 IEEE Intl. Symp. Biomed. Imag. Macro Nano, Washington DC, July 7-10, 2002, Paper MP-P204 (2002).
8. A. Durkin, S. Jaikumar, and R. Richards-Kortum, "Optically dilute, absorbing, and turbid phantoms for fluorescence spectroscopy of homogeneous and inhomogeneous samples", Appl. Spectrosc. 47, 2114-2121 (1993).
9. J. Wahlfors, S. Loimas, T. Pasanen, and T. Hakkarainen, "Green fluorescent protein (GFP) fusion constructs in gene therapy research", Histochem. Cell Biol. 115, 59-65 (2001). (Pubitemid 32202054)
10. X. Du, B. Qiu, X. Zhan, A. Kolmakova, F. Gao, L. Hofmann, L. Cheng, S. Chatterjee, and X. Yang, "Intravascular MR/radiofrequency-enhanced vascular gene transduction/expression: feasibility study in pigs", Radiology 236, 939-944 (2005). (Pubitemid 41170857)
11. M. Chalfie, Y. Tu, G. Euskirchen, W. Ward, and D. Prasher, "Green fluorescent protein as a marker for gene expression", Science 263, 802-805 (1994). (Pubitemid 24093206)
12. R. Tsien, "The green fluorescent protein", Annu. Rev. Biochem. 67, 509 (1998).
13. X. Yu, X. Zhan, J. D'Costa, V. Tanavde, Z. Ye, T. Peng, M. Malehorn, X. Yang, C. Civin, and L. Cheng, "Lentiviral vector with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells", Mol. Ther. 7, 827-838 (2003). (Pubitemid 36790260)