Association of umbilical cord blood lead with neonatal behavior at varying levels of exposure

Behavioral and Brain Functions

Volumn 2, Issue , 2006, Pages

  Patel, Archana B ^a,b   Mamtani, Manju R ^b   Thakre, Tushar P ^b,c   Kulkarni, Hemant ^b  

^a GOVERNMENT MEDICAL COLLEGE   (India)

^b Lata Medical Research Foundation   (India)

^c UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEAD;

ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BEHAVIOR DISORDER; BRAZELTON NEONATAL BEHAVIORAL ASSESSMENT SCALE; CHILD BEHAVIOR; CLUSTER ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; INTERMETHOD COMPARISON; LEAD BLOOD LEVEL; LEAD POISONING; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NEWBORN; POISSON DISTRIBUTION; PRENATAL EXPOSURE; PRIORITY JOURNAL; REFLEX DISORDER; STRUCTURAL EQUATION MODELING; TERATOGENICITY; UMBILICAL CORD BLOOD; WALKING DIFFICULTY;

EID: 33748438133     PISSN: 17449081     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-9081-2-22     Document Type: Article

References (69)

1. Ernhart CB: Lead levels and confounding variables. Am J Psychiatry 1982, 139:1524.
2. Ernhart CB: Inconsistencies in the lead-effects literature exist and cannot be explained by "effect modification". Neurotoxicol Teratol 1995, 17:227-33. discussion 249-251.
3. Ernhart CB: Lead effects research. Am J Public Health 1998, 88:1879-1880.
4. Needleman H: Lead poisoning. Annu Rev Med 2004, 55:209-222.
5. Needleman HL, Landrigan PJ: What level of lead in blood is toxic for a child? Am J Public Health 2004, 94:8-9.
6. Scarr S, Ernhart CB: Of whistleblowers, investigators, and judges. Ethics Behav 1993, 3:199-206.
7. Oberto A, Marks N, Evans HL, Guidott A: Lead (Pb+2) promotes apoptosis in newborn rat cerebellar neurons: pathological implications. J Pharmacol Exp Ther 1996, 279:435-442.
8. Shen X, Wu S, Yan C: Impacts of low-level lead exposure on development of children: recent studies in China. Clin Chim Acta 2001, 313:217-220.
9. Dietrich KN, Ris MD, Succop, PA, Berger OG, Bornschein RL: Early exposure to lead and juvenile delinquency. Neurotoxicol Teratol 2001, 23:511-518.
10. Pabello NG, Bolivar VJ: Young brains on lead: adult neurological consequences? Toxicol Sci 2005, 86:211-213.
11. Bellinger DC, Hu H, Kalaniti K, Thomas N, Rajan P, Sambandam S, Ramaswamy P, Balakrishnan K: A pilot study of blood lead levels and neurobehavioral function in children living in Chennai, India. Int J Occup, Environ Health 2005, 11:138-143.
12. Canfield RL, Gendle MH, Cory-Slechta DA: Impaired neuropsychological functioning in lead-exposed children. Dev Neuropsychol 2004, 26:513-540.
13. Canfield RL, Kreher DA, Cornwell C, Henderson CR Jr: Low-level lead exposure, executive functioning, and learning in early childhood. Neuropsychol Dev Cogn C Child Neuropsychol 2003, 9:35-53.
14. Chen A, Dietrich KN, Ware JH, Radcliffe J, Rogan WJ: IQ and blood lead from 2 to 7 years of age: are the effects in older children the residual of high blood lead concentrations in 2-year-olds? Environ Health Perspect 2005, 113:597-601.
15. Chiodo LM, Jacobson SW, Jacobson JL: Neurodevelopmental effects of postnatal lead exposure at very low levels. Neurotoxicol Teratol 2004, 26:359-371.
16. Ozmert EN, Yurdakok K, Soysal S, Kulak-Kayikci ME, Belgin E, Ozmert E, Laleli Y, Sarachasi O: Relationship between physical, environmental and sociodemographic factors and school performance in primary schoolchildren. J Trop Pediatr 2005, 51:25-32.
17. Pocock SJ, Smith M, Baghurst P: Environmental lead and children's intelligence: a systematic review of the epidemiological evidence. BMJ 1994, 309:1189-1197.
18. Schwartz J: Low-level lead exposure and children's IQ: a meta-analysis and search for a threshold. Environ Res 1994, 65:42-55.
19. Holmes SE, Slaughter JR, Kashani J: Risk factors in childhood that lead to the development of conduct disorder and antisocial personality disorder. Child Psychiatry Hum Dev 2001, 31:183-193.
20. Stretesky PB, Lynch MJ: The relationship between lead exposure and homicide. Arch Pediatr Adolesc Med 2001, 155:579-582.
21. Ernhart CB, Wolf AW, Kennard MJ, Erhard P, Filipovich HF, Sokol RJ: Intrauterine exposure to low levels of lead: the status of the neonate. Arch Environ Health 1986, 41:287-291.
22. Rothenberg SJ, Schnaas L, Cansino-Ortiz S, Perroni-Hernandez E, de la Torre P, Neri-Mendez C, Ortega P, Hidalgo-Loperena H, Svendsgaard D: Neurobehavioral deficits after low level lead exposure in neonates: the Mexico City pilot study. Neurotoxicol Teratol 1989, 11:85-93.
23. Emory E, Pattilo, R, Archibold E, Bayorh M, Sung F: Neurobehavioral effects of low-level lead exposure in human neonates. Am J Obstet Gynelcol 1999, 181:S2-S11.
24. Shen X-M, Yan C-H, Guo D, Wu S-M, Li R-Q, Huang H, Ao L-M, Zhou J-D, Hong Z-Y, Xu J-D, Jin X-M, T J-M: Low level prenatal lead exposure and neurobehavioral development of children in the first year of life: A prospective study in Shanghai. Environ Res 1998, 79:1-8.
25. Gomaa A, Hu H, Bellinger D, Schwartz J, Tsaih SW, Gonzalez-Cossio T, Schnaas L, Peterson K, Aro A, Hernandez-Avila M: Maternal bone lead as an independent risk factor for fetal neurotoxicity: a prospective study. Pediatrics 2002, 110:110-118.
26. Tronick EZ: The neonatal behavioral assessment scale as a biomarker of the effects of environmental agents on the newborn. Environ Health Perspect 1987, 74:185-189.
27. Brazelton TB, Nugent JK: Neonatal Behavioral Assessment Scale 3rd edition. London: Mac Keith Press; 1995.
28. Lester BM, Als H, Brazelton TB: Regional obstetric anesthesia and newborn behavior: a reanalysis toward synergistic effects. Child Dev 1982, 53:687-692.
29. Lagesson V, Andrasko L: Direct determination of lead and cadmium in blood and urine by flameless atomic absorption spectrophotometry. Clin Chem 1979, 25:1948-1953.
30. Bollen KA: The General Model. In Structural equations with latent variables John Wiley & Sons: New York, 1989:319-448.
31. Bhutta AT: Anand KJ: Vulnerability of the developing brain. Neuronal mechanisms. Clin Perinatol 2002, 29:357-372.
32. Rice D, Barone S Jr. Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models. Environ Health Perspect 2000, 108:511-533.
33. Rakic P: Images in neuroscience. Brain development, VI: radial migration and cortical evolution. Am J Psychiatry 1998, 155:1150-1151.
34. Rakic P, Bourgeois J-P, Eckenhoff MF, Zecevic N, Goldman-Rakic PS: Concurrent overproduction of synapses in diverse regions of the primate cerebral cortex. Science 1986, 232:232-235.
35. Gould E, Cameron HA: Early NMDA receptor blockade impairs defensive behavior and increases cell proliferation in the dentate gyrus of developing rats. Behav Neurosci 1997, 111:49-56.
36. Rao H, Jean A, Kessler JP: Postnatal ontogeny of glutamate receptors in the rat: nucleus tractus solitarii and ventrolateral medulla. J Auton Nerv Syst 1997, 65:25-32.
37. Chahal H, D'Souza SW, Barson AJ, Slater P: Modulation by magnesium of N-methyl-Daspartate receptors in developing human brain. Arch Dis Child Fetal Neonatal Ed 1998, 78:F116-F120.
38. Toscano CD, Guilarte TR: Lead neurotoxicity: from exposure to molecular effects. Brain Dev Brain Res Rev 2005, 49:529-554.
39. Uylings HB, Malofeeva LI, Bogolepova IN, Jacobsen AM, Amunts K, Zilles K: No postnatal doubling of number of neurons in human Broca's areas (Brodmann areas 44 and 45)? A stereological study. Neuroscience 2005, 136:715-728.
40. Travis K. Ford K, Jacobs B: Regional dendritic variation in neonatal human cortex: a quantitative Golgi study. Dev Neurosci 2005, 27:277-287.
41. Guillery RW: Is postnatal neocortical maturation hierarchical? Trends Neurosci 2005, 28:512-517.
42. Yu K, Yu SS, Ruan DY: Opposite effects of lead exposure on taurine- and HFS-induced LTP in rat hippocampus. Brain Res Bull 2005, 64:525-531.
43. Booze RM, Mactutus CF: Developmental exposure to organic lead causes permanent hippocampal damage in Fischer-344 rats. Experientia 1990, 46:292-297.
44. Virgolini MB, Chen K, Wetson DD, Bauter MR, Cory-Slechta DA: Interactions of chronic lead exposure and intermittent stress: consequences for brain catecholamine systems and associated behaviors and HPA axis function. Toxicol Sci 2005, 87:469-482.
45. Schneider M, Koch M: Behavioral and morphological alterations following neonatal excitotoxic lesions of the medial prefrontal cortex in rats. Exp Neurol 2005, 195:185-198.
46. Ma T, Chen HH, Lim DK, Hume AS, Ho IK: Excitatory amino acids and lead-induced neurotoxicity. J Toxicol Sci 1998, 23:181-183.
47. Zhu ZW, Yang RL, Dong GJ, Zhao ZY: Study on the neurotoxic effects of low-level lead exposure in rats. J Zhejiang Univ Sci B 2005, 6:686-692.
48. Strange BA, Fletcher PC, Henson RN, Friston KJ, Dolan RJ: Segregating the functions of human hippocampus. Proc Natl Acad Sci USA 1999, 96:4034-4039.
49. Wood JN, Grafman J: Human Prefrontal Cortex: processing and representational perspectives. Nature Reviews Neuroscience 2003, 4:139-147.
50. Strange BA, Henson RN, Friston KJ, Dolan RJ: Anterior prefrontal cortex mediates rule learning in humans. Cereb Cortex 2001, 11:1040-1046.
51. Kaldy Z, Sigala N: The neural mechanisms of object working memory: what is where in the infant brain? Neurosci Biobehav Rev 2004, 28:113-121.
52. Factor-Litvak P, Wasserman G, Kline JK, Graziano J: The Yugoslavia Prospective Study of environmental lead exposure. Environ Health Perspect 1999, 107:9-15.
53. Schnaas L, Rothenberg SJ, Flores MF, Martinez S, Hernandez C, Osorio E, Velasco SR, Perroni E: Reduced intellectual development in children with prenatal lead exposure. Environ Health Perspect 2006, 114:791-797.
54. Bellinger DC: Assessing environmental neurotoxicant exposures and child neurobehavior: confounded by confounding? Epidemiology 2004, 15:383-384.
55. Bellinger DC: Lead. Pediatrics 2004, 113:1016-1022.
56. Ernhart CB: A critical review of low-level prenatal lead exposure in the human: 1. Effects on the fetus and newborn. Reprod Toxicol 1992, 6:9-19.
57. Gardella C: Lead exposure in pregnancy: a review of the literature and argument for routine prenatal screening. Obstet Gynecol Surv 2001, 56:231-238.
58. Wong GP, Ng TL, Martin TP, Farquharson DF: Effects of low-level lead exposure in utero. Obstet Gynecol Surv 1992, 47:285-289.
59. Carrillo-Ponce Mde L, Martinez-Ordaz VA, Velasco-Rodriguez VM, Hernandez-Garcia A, Hernandez-Serrano MC, Sanmiguell F: Serum lead, cadmium, and zinc levels in newborns with neural tube defects from a polluted zone in Mexico. Reprod Toxicol 2004, 19:149-154.
60. Stewart P, Reihman J, Lonky E, Darvill T, Pagano J: Prenatal PCB exposure and neonatal behavioral assessment scale (NBAS) performance. Neurotoxicol Teratol 2000, 22:21-29.
61. Antonio MT, Corpas I, Leret ML: Neurochemical changes in newborn rat's brain after gestational cadmium and lead exposure. Toxicol Lett 1999, 104:1-9.
62. Bilbo SD, Rudy JW, Watkins LR, Maier SF: A behavioural characterization of neonatal infection-facilitated memory impairment in adult rats. Behav Brain Res 2006, 169:39-47.
63. Schneider M, Koch M: Behavioral and morphological alterations following neonatal excitotoxic lesions of the medial prefrontal cortex in rats. Exp Neurol 2005, 195:185-198.
64. McEwen BS: Early life influences on life-long patterns of behavior and health. Ment Retord Dev Disabil Res Rev 2003, 9:149-154.
65. Bull SB: Regression models for multiple outcomes in large epidemiologic studies. Stat Med 1998, 17:2179-2197.
66. Sargent JD, Dalton M, Klein RZ: Diagnostic testing unwarranted for children with blood lead 10 to 14 microg/dL. Pediatrics 1999, 103:e51.
67. Binns HJ, Kim D, Campbell C: Targeted screening for elevated blood lead levels: populations at high risk. Pediatrics 2001, 108:1364-1366.
68. Binns HJ, LeBailly SA, Fingar AR, Saunders S: Evaluation of risk assessment questions used to target blood lead screening in Illinois. Pediatrics 1999, 103:100-106.
69. Litaker D, Kippes CM, Gallagher TE, O'Connor ME: Targeting lead screening: The Ohio Lead Risk Score. Pediatrics 2000, 106:E69.