Dendritic cell recruitment following xenografting of pig fetal mesencephalic cells into the rat brain

Experimental Neurology

Volumn 202, Issue 1, 2006, Pages 76-84

  Michel, Delphine C ^a,b,c   Nerrière Daguin, Véronique ^a,b,c   Josien, Régis ^a,b,c   Brachet, Philippe ^a,b,c   Naveilhan, Philippe ^a,b,c   Neveu, Isabelle ^a,b,c  

^a INSERM   (France)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE NANTES   (France)

Author keywords

Astrocyte; CD4; CD8; Immune response; Microglial cell; Neurodegenerative disease; Neuron; Parkinson's disease; Xenotransplantation

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; BRAIN GRAFT; CELL COUNT; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MIGRATION; CELL TYPE; CONTROLLED STUDY; CORPUS STRIATUM; DENDRITIC CELL; EMBRYO; GRAFT REJECTION; LYMPHOCYTIC INFILTRATION; MACROPHAGE; MALE; MESENCEPHALON; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; SWINE; T LYMPHOCYTE SUBPOPULATION; XENOGRAFT;

ANIMALS; ANTIGENS, DIFFERENTIATION; BRAIN; CELL COUNT; DENDRITIC CELLS; ECTODYSPLASINS; EMBRYO; EMBRYO, MAMMALIAN; FETAL TISSUE TRANSPLANTATION; GRAFT REJECTION; IMMUNOHISTOCHEMISTRY; MALE; MESENCEPHALON; NEURONS; RATS; RATS, INBRED LEW; SWINE; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 33748435314     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2006.05.021     Document Type: Article

References (33)

1. Armstrong R.J., Harrower T.P., Hurelbrink C.B., McLaughin M., Ratcliffe E.L., Tyers P., Richards A., Dunnett S.B., Rosser A.E., and Barker R.A. Porcine neural xenografts in the immunocompetent rat: immune response following grafting of expanded neural precursor cells. Neuroscience 106 (2001) 201-216
2. Barker R.A., Ratcliffe E., McLaughlin M., Richards A., and Dunnett S.B. A role for complement in the rejection of porcine ventral mesencephalic xenografts in a rat model of Parkinson's disease. J. Neurosci. 20 (2000) 3415-3424
3. Cardona A.E., and Teale J.M. Gamma/delta T cell-deficient mice exhibit reduced disease severity and decreased inflammatory response in the brain in murine neurocysticercosis. J. Immunol. 169 (2002) 3163-3171
4. Cardona A.E., Restrepo B.I., Jaramillo J.M., and Teale J.M. Development of an animal model for neurocysticercosis: immune response in the central nervous system is characterized by a predominance of gamma delta T cells. J. Immunol. 162 (1999) 995-1002
5. Curtin J.F., King G.D., Barcia C., Liu C., Hubert F.X., Guillonneau C., Josien R., Anegon I., Lowenstein P.R., and Castro M.G. Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. J. Immunol. 176 (2006) 3566-3577
6. Depino A.M., Earl C., Kaczmarczyk E., Ferrari C., Besedovsky H., del Rey A., Pitossi F.J., and Oertel W.H. Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease. Eur. J. Neurosci. 18 (2003) 2731-2742
7. Duan W.M., Westerman M.A., Wong G., and Low W.C. Rat nigral xenografts survive in the brain of MHC class II-, but not class I-deficient mice. Neuroscience 115 (2002) 495-504
8. Fischer H.G., and Reichmann G. Brain dendritic cells and macrophages/microglia in central nervous system inflammation. J. Immunol. 166 (2001) 2717-2726
9. Galpern W.R., Burns L.H., Deacon T.W., Dinsmore J., and Isacson O. Xenotransplantation of porcine fetal ventral mesencephalon in a rat model of Parkinson's disease: functional recovery and graft morphology. Exp. Neurol. 140 (1996) 1-13
10. Greter M., Heppner F.L., Lemos M.P., Odermatt B.M., Goebels N., Laufer T., Noelle R.J., and Becher B. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat. Med. 11 (2005) 328-334
11. Harling-Berg C.J., Park T.J., and Knopf P.M. Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation. J. Neuroimmunol. 101 (1999) 111-127
12. Herman J.P., and Abrous N.D. Dopaminergic neural grafts after fifteen years: results and perspectives. Prog. Neurobiol. 44 (1994) 1-35
13. Hubert F.X., Voisine C., Louvet C., Heslan M., and Josien R. Rat plasmacytoid dendritic cells are an abundant subset of MHC class II+ CD4+CD11b-OX62- and type I IFN-producing cells that exhibit selective expression of Toll-like receptors 7 and 9 and strong responsiveness to CpG. J. Immunol. 172 (2004) 7485-7494
14. Itano A.A., McSorley S.J., Reinhardt R.L., Ehst B.D., Ingulli E., Rudensky A.Y., and Jenkins M.K. Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated. Immunity 19 (2003) 47-57
15. Karman J., Ling C., Sandor M., and Fabry Z. Initiation of immune responses in brain is promoted by local dendritic cells. J. Immunol. 173 (2004) 2353-2361
16. Larsson L.C., Czech K.A., Widner H., and Korsgren O. Discordant neural tissue xenografts survive longer in immunoglobulin deficient mice. Transplantation 68 (1999) 1153-1160
17. Larsson L.C., Frielingsdorf H., Mirza B., Hansson S.J., Anderson P., Czech K.A., Strandberg M., and Widner H. Porcine neural xenografts in rats and mice: donor tissue development and characteristics of rejection. Exp. Neurol. 172 (2001) 100-114
18. Lindvall O., and Bjorklund A. Cell therapy in Parkinson's disease. NeuroRx 1 (2004) 382-393
19. Liu L., Zhang M., Jenkins C., and MacPherson G.G. Dendritic cell heterogeneity in vivo: two functionally different dendritic cell populations in rat intestinal lymph can be distinguished by CD4 expression. J. Immunol. 161 (1998) 1146-1155
20. Matyszak M.K., and Perry V.H. The potential role of dendritic cells in immune-mediated inflammatory diseases in the central nervous system. Neuroscience 74 (1996) 599-608
21. Melchior B., Remy S., Nerriere-Daguin V., Heslan J.M., Soulillou J.P., and Brachet P. Temporal analysis of cytokine gene expression during infiltration of porcine neuronal grafts implanted into the rat brain. J. Neurosci. Res. 68 (2002) 284-292
22. Melchior B., Nerriere-Daguin V., Laplaud D.A., Remy S., Wiertlewski S., Neveu I., Naveilhan P., Meakin S.O., and Brachet P. Ectopic expression of the TrkA receptor in adult dopaminergic mesencephalic neurons promotes retrograde axonal NGF transport and NGF-dependent neuroprotection. Exp. Neurol. 183 (2003) 367-378
23. Melchior B., Nerriere-Daguin V., Degauque N., Brouard S., Guillet M., Soulillou J.P., and Brachet P. Compartmentalization of TCR repertoire alteration during rejection of an intrabrain xenograft. Exp. Neurol. 192 (2005) 373-383
24. Newman T.A., Galea I., van Rooijen N., and Perry V.H. Blood-derived dendritic cells in an acute brain injury. J. Neuroimmunol. 166 (2005) 167-172
25. Perry V.H. The influence of systemic inflammation on inflammation in the brain: implications for chronic neurodegenerative disease. Brain Behav. Immun. 18 (2004) 407-413
26. Remy S., Canova C., Daguin-Nerriere V., Martin C., Melchior B., Neveu I., Charreau B., Soulillou J.P., and Brachet P. Different mechanisms mediate the rejection of porcine neurons and endothelial cells transplanted into the rat brain. Xenotranspl. (Kbh.) 8 (2001) 136-148
27. Santambrogio L., Belyanskaya S.L., Fischer F.R., Cipriani B., Brosnan C.F., Ricciardi-Castagnoli P., Stern L.J., Strominger J.L., and Riese R. Developmental plasticity of CNS microglia. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 6295-6300
28. Siveke J.T., and Hamann A. Cutting edge: T helper 1 and T helper 2 cells respond differentially to chemokines. J. Immunol. 160 (1998) 550-554
29. Slavin A.J., Soos J.M., Stuve O., Patarroyo J.C., Weiner H.L., Fontana A., Bikoff E.K., and Zamvil S.S. Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoImmunity. J. Clin. Invest. 108 (2001) 1133-1139
30. Trifilo M.J., and Lane T.E. The CC chemokine ligand 3 regulates CD11c+CD11b+CD8alpha- dendritic cell maturation and activation following viral infection of the central nervous system: implications for a role in T cell activation. Virology 327 (2004) 8-15
31. Trinite B., Voisine C., Yagita H., and Josien R. A subset of cytolytic dendritic cells in rat. J. Immunol. 165 (2000) 4202-4208
32. Voisine C., Hubert F.X., Trinite B., Heslan M., and Josien R. Two phenotypically distinct subsets of spleen dendritic cells in rats exhibit different cytokine production and T cell stimulatory activity. J. Immunol. 169 (2002) 2284-2291
33. Wood M.J., Sloan D.J., Wood K.J., and Charlton H.M. Indefinite survival of neural xenografts induced with anti-CD4 monoclonal antibodies. Neuroscience 70 (1996) 775-789