Critical appraisal of the management of severe malnutrition: 3. Complications

Journal of Paediatrics and Child Health

Volumn 42, Issue 10, 2006, Pages 583-593

  Brewster, David R ^a  

^a FIJI SCHOOL OF MEDICINE   (Fiji)

Author keywords

Enteropathy; HIV; Hypoglycaemia; Hypophosphataemia; Malnutrition; Sepsis; TB

Indexed keywords

AMOXICILLIN; AMPICILLIN; ANTHELMINTIC AGENT; ANTIBIOTIC AGENT; ANTIMALARIAL AGENT; CHLORAMPHENICOL; CHLORIDE; CITRIC ACID; COPPER; COTRIMOXAZOLE; GENTAMICIN; GLUCOSE; LACTIC ACID; MAGNESIUM; METRONIDAZOLE; ORAL REHYDRATION SOLUTION; POTASSIUM; RIFAXIMIN; SODIUM; ZINC;

AMEBIASIS; ANTIBIOTIC RESISTANCE; ARTIFICIAL MILK; BACTERIAL INFECTION; CHILDHOOD MORTALITY; CHOLERA; CLINICAL TRIAL; CONFIDENCE INTERVAL; CRYPTOSPORIDIOSIS; DEHYDRATION; DIARRHEA; ELECTROLYTE DISTURBANCE; EMOTION; ENTEROBACTERIACEAE; ENTEROPATHY; FLUID THERAPY; GIARDIASIS; GROWTH DISORDER; HEART FAILURE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOGLYCEMIA; HYPOKALEMIA; HYPONATREMIA; INFECTION; KWASHIORKOR; LACTOSE INTOLERANCE; LUNG TUBERCULOSIS; MALNUTRITION; MARASMUS; NUTRITION; OPPORTUNISTIC INFECTION; ORAL REHYDRATION THERAPY; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; PYREXIA IDIOPATHICA; REVIEW; SEPSIS; SEPTICEMIA; SHOCK; URINARY TRACT INFECTION; WEANING;

CHILD; HUMANS; HYPOGLYCEMIA; INTESTINAL DISEASES; MALNUTRITION; SEVERITY OF ILLNESS INDEX; TUBERCULOSIS;

EID: 33748425127     PISSN: 10344810     EISSN: 14401754     Source Type: Journal    
DOI: 10.1111/j.1440-1754.2006.00933.x     Document Type: Review

References (113)

1. Brewster DR. Dehydration in acute gastroenteritis. J. Paediatr. Child Health 2002; 38: 219-22.
2. Alam NH, Hamadani JD, Dewan N, Fuchs GJ. Efficacy and safety of a modified oral rehydration solution (ReSoMaL) in the treatment of severely malnourished children with watery diarrhea. J. Pediatr. 2003; 143: 614-19.
3. Hahn S, Kim S, Garner P. Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in children (Cochrane Review). Cochrane Database Syst. Rev. 2002; 1: CD002847.
4. Fontaine O, Gore SM, Pierce NF. Rice-based oral rehydration solution for treating diarrhoea. Cochrane Database Syst. Rev. 2000; 2: CD001264.
5. Manary MJ, Brewster DR. Potassium supplementation in kwashiorkor. J. Pediatr. Gastroenterol. Nutr. 1997; 24: 194-201.
6. Kukuruzovic R, Haase A, Dunn K, Bright A, Brewster DR. Intestinal permeability and diarrhoeal disease in Aboriginal Australians. Arch. Dis. Child. 1999; 81: 304-8.
7. Kukuruzovic R, Brewster DR. Small bowel intestinal permeability in Australian Aboriginal children. J. Pediatr. Gastroenterol. Nutr. 2002; 35: 206-12.
8. Lindenbaum J. Tropical enteropathy. Gastroenterology 1973; 64: 637-52.
9. Lindenbaum J, Harmon JW, Gerson CD. Subclinical malabsorption in developing countries. Am. J. Clin. Nutr. 1972; 25: 1056-61.
10. Schenk EA, Klipstein FA. Tropical jejunitis (tropical enteropathy). A protocol for the evaluation of small bowel biopsies. Am. J. Clin. Nutr. 1972; 25: 1108-17.
11. Klipstein FA. Recent advances in tropical malabsorption. Scand. J. Gastroenterol. Suppl. 1970; 6: 93-114.
12. Chacko CJ, Paulson KA, Mathan VI, Baker SJ. The villus architecture of the small intestine in the tropics: a necropsy study. J. Pathol. 1969; 98: 146-51.
13. Campbell DI, Elia M, Lunn PG. Growth faltering in rural Gambian infants is associated with impaired small intestinal barrier function, leading to endotoxemia and systemic inflammation. J. Nutr. 2003; 133: 1332-8.
14. Goto R, Panter-Brick C, Northrop-Clewes CA, Manahdhar R, Tuladhar NR. Poor intestinal permeability in mildly stunted Nepali children: associations with weaning practices and Giardia lamblia infection. Br. J. Nutr. 2002; 88: 141-9.
15. Brewster DR. Intestinal permeability in protein-energy malnutrition. In: Bhutta ZA, ed. Contemporary Issues in Childhood Diarrhoea and Malnutrition. Oxford: Oxford University Press, 2000; 125-203.
16. Fagundes-Neto U, Viaro T, Wehba J, Patricio FR, Machado NL. Tropical enteropathy (environmental enteropathy) in early childhood: a syndrome caused by contaminated environment. J. Trop. Pediatr. 1984; 30: 204-9.
17. Fagundes-Neto U, Martins MC, Lima FL, Patricio FR, Toledo MR. Asymptomatic environmental enteropathy among slum-dwelling infants. J. Am. Coll. Nutr. 1994; 13: 51-6.
18. Lunn PG. Growth retardation and stunting of children in developing countries. Br. J. Nutr. 2002; 88: 109-10.
19. Lunn PG. The impact of infection and nutrition on gut function and growth in childhood. Proc. Nutr. Soc. 2000; 59: 147-54.
20. Northrop Clewes CA, Lunn PG, Downes RM. Lactose maldigestion in breast-feeding Gambian infants. J. Pediatr. Gastroenterol. Nutr. 1997; 24: 257-63.
21. Lunn PG, Northrop Clewes CA, Downes RM. Intestinal permeability, mucosal injury, and growth faltering in Gambian infants. Lancet 1991; 338: 907-10.
22. Campbell DI, Lunn PG, Elia M. Age-related association of small intestinal mucosal enteropathy with nutritional status in rural Gambian children. Br. J. Nutr. 2002; 88: 499-505.
23. Campbell DI, Murch SH, Elia M et al. Chronic T cell-mediated enteropathy in rural West African children: relationship with nutritional status and small bowel function. Pediatr. Res. 2003; 54: 1-6.
24. Veitch AM, Kelly P, Zulu IS, Segal I, Farthing MJ. Tropical enteropathy: a T-cell-mediated crypt hyperplastic enteropathy. Eur. J. Gastroenterol. Hepatol. 2001; 13: 1175-81.
25. Murch SH, Fertleman CR, Rodrigues C et al. Autoimmune enteropathy with distinct mucosal features in T-cell activation deficiency: the contribution of T cells to the mucosal lesion. J. Pediatr. Gastroenterol. Nutr. 1999; 28: 393-9.
26. Brewster DR, Manary MJ, Menzies IS, Henry RL, O'Loughlin EV. Comparison of milk and maize-based diets in kwashiorkor. Arch. Dis. Child. 1997; 76: 242-8.
27. Waterlow JC. Protein-Energy Malnutrition. London: Edward Arnold, 1992.
28. Walker-Smith J, Barnard J, Bhutta Z, Heubi J, Reeves Z, Schmitz J. Chronic diarrhea and malabsorption (including short gut syndrome): working group report of the first world congress of pediatric gastroenterology, hepatology, and nutrition. J. Pediatr. Gastroenterol. Nutr. 2002; 35 (Suppl.): S98-105.
29. Sullivan PB, Marsh MN, Phillips MB et al. Prevalence and treatment of giardiasis in chronic diarrhoea and malnutrition. Arch. Dis. Child. 1991; 66: 304-6.
30. Campbell DI, McPhail G, Lunn PG, Elia M, Jeffries D. Intestinal inflammation measured by fecal neopterin concentration in Gambian children with enteropathy: association with growth faltering, Giardia lamblia, and intestinal permeability. J. Pediatr. Gastroenterol. Nutr. 2004; 39: 153-7.
31. Baqui AH, Zaman K, Yunus M, Mitra AK, Hossain KM, Banu H. Epidemiological and clinical characteristics of shigellosis in rural Bangladesh. J. Diarrhoeal Dis. Res. 1988; 6: 21-8.
32. Ahmed F, Clemens JD, Rao MR, Ansaruzzaman M, Haque E. Epidemiology of shigellosis among children exposed to cases of Shigella dysentery: a multivariate assessment. Am. J. Trop. Med. Hyg. 1997; 56: 258-64.
33. Rahman MM, Kabir I, Mahalanabis D, Malek MA. Decreased food intake in children with severe dysentery due to Shigella dysenteriae 1 infection. Eur. J. Clin. Nutr. 1992; 46: 833-8.
34. Kukuruzovic RH, Brewster DR, Gray E, Anstey NM. Increased nitric oxide production in acute diarrhoea is associated with abnormal gut permeability, hypokalaemia and malnutrition in tropical Australian Aboriginal children. Trans. R. Soc. Trop. Med. Hyg. 2003; 97: 115-20.
35. Kukuruzovic RH, Robins Browne RM, Anstey N, Brewster DR. Enteric pathogens, intestinal permeability and nitric oxide production in acute gastroenteritis. Pediatr. Infect. Dis. J. 2002; 21: 730-9.
36. Mata L. Diarrheal disease as a cause of malnutrition. Am. J. Trop. Med. Hyg. 1992; 47 (Suppl.): 16-27.
37. Mata LJ, Urrutia JJ, Albertazzi C, Pellecer O, Arellano E. The American Journal of Clinical Nutrition, Volume 25, 1972: Influence of recurrent infections on nutrition and growth of children in Guatemala [Classical Article]. Nutr. Rev. 1991; 49: 269-72.
38. Mata LJ. The Children of Santa Maria Cauque: A Prospective Field Study of Health and Growth. Cambridge, MA: MIT, 1978.
39. Briend A. Is diarrhoea a major cause of malnutrition among the under-fives in developing countries? A review of available evidence. Eur. J. Clin. Nutr. 1990; 44: 611-28.
40. Torun B, Solomons NW, Caballero B, Flores-Huerta S, Orozco G, Pineda O. The effect of dietary lactose on the early recovery from protein-energy malnutrition. II. Indices of nutrient absorption. Am. J. Clin. Nutr. 1984; 40: 601-10.
41. Solomons NW, Torun B, Caballero B, Flores-Huerta S, Orozco G. The effect of dietary lactose on the early recovery from protein-energy malnutrition. I. Clinical and anthropometric indices. Am. J. Clin. Nutr. 1984; 40: 591-600.
42. Walker-Smith JA, Murch SH. Diseases of the Small Intestine in Childhood, 4th edn. Oxford: Isis Medical Media, 1999.
43. Walker-Smith JA, Reye RD. Small intestinal morphology in aboriginal children. Aust. N. Z. J. Med. 1971; 1: 377-84.
44. Nichols BL, Nichols VN, Putman M et al. Contribution of villous atrophy to reduced intestinal maltase in infants with malnutrition. J. Pediatr. Gastroenterol. Nutr. 2000; 30: 494-502.
45. Nichols BL, Eldering J, Avery SE, Hahn D, Quaroni A, Sterchi E. Human small intestinal maltase-glucoamylase cDNA cloning: homology to sucrase-isomaltase. J. Biol. Chem. 1998; 273: 3076-81.
46. Nichols BL, Dudley MA, Nichols VN et al. Effects of malnutrition on expression and activity of lactase in children. Gastroenterology 1997; 112: 742-51.
47. Nichols BL, Carrazza F, Nichols VN et al. Mosaic expression of brush-border enzymes in infants with chronic diarrhea and malnutrition. J. Pediatr. Gastroenterol. Nutr. 1992; 14: 371-9.
48. Nichols BL, Nichols VN. Carbohydrate maldigestion and malabsorption. In: Brunser O, Carrazza FR, Nichols BL, Gracey M, Senterre J, eds. Clinical Nutrition of the Young Child. New York: Raven, 1990; 217-40.
49. Taylor C, Hodgson K, Sharpstone D et al. The prevalence and severity of intestinal disaccharidase deficiency in human immunodeficiency virus-infected subjects. Scand. J. Gastroenterol. 2000; 35: 599-606.
50. Gracey M, Stone DE, Suharjono S. Oro-pharyngeal microflora in malnourished children. Aust. Paediatr. J. 1973; 9: 260-2.
51. Gracey M, Suharjono, Sunoto, Stone DE. Microbial contamination of the gut: another feature of malnutrition. Am. J. Clin. Nutr. 1973; 26: 1170-4.
52. Gracey M, Stone DE. Small-intestinal microflora in Australian Aboriginal children with chronic diarrhoea. Aust. N. Z. J. Med. 1972; 2: 215-19.
53. Gracey M. Intestinal absorption in the 'contaminated small-bowel syndrome'. Gut 1971; 12: 403-10.
54. Riordan SM, McIver CJ, Duncombe VM, Thomas MC, Bolin TD. Evaluation of the rice breath hydrogen test for small intestinal bacterial overgrowth. Am. J. Gastroenterol. 2000; 95: 2858-64.
55. Riordan SM, McIver CJ, Walker BM, Duncombe VM, Bolin TD, Thomas MC. The lactulose breath hydrogen test and small intestinal bacterial overgrowth. Am. J. Gastroenterol. 1996; 91: 1795-803.
56. Riordan SM, McIver CJ, Bolin TD, Duncombe VM. Fasting breath hydrogen concentrations in gastric and small-intestinal bacterial overgrowth. Scand. J. Gastroenterol. 1995; 30: 252-7.
57. Dellert SF, Nowicki MJ, Farrell MK, Delente J, Heubi JE. The 13C-xylose breath test for the diagnosis of small bowel bacterial overgrowth in children. J. Pediatr. Gastroenterol. Nutr. 1997; 25: 153-8.
58. Gillis JC, Brogden RN. Rifaximin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria. Drugs 1995; 49: 467-84.
59. Anonymous. Treatment of Tuberculosis: Guidelines for National Programmes. WHO/CDS/TB/2003.313, 1. 2003. Third edition (English). Geneva: WHO, 2003.
60. Stegen G, Jones K, Kaplan P. Criteria for guidance in the diagnosis of tuberculosis. Pediatrics 1969; 43: 260-3.
61. Edwards K. The diagnosis of childhood tuberculosis. P. N. G. Med. J. 1987; 30: 169-78.
62. Narayan S, Mahadevan S, Serane VT. Keith Edwards score for diagnosis of tuberculosis. Indian J. Pediatr. 2004; 70: 467-9.
63. van Rheenen P. The use of the paediatric tuberculosis score chart in an HIV-endemic area. Trop. Med. Int. Health 2002; 7: 435-41.
64. Cruciani M, Marcati P, Malena M, Bosco O, Serpelloni G, Mengoli C. Meta-analysis of diagnostic procedures for Pneumocystis carinii pneumonia in HIV-1-infected patients. Eur. Respir. J. 2002; 20: 982-9.
65. Zar HJ, Tannenbaum E, Hanslo D, Hussey G. Sputum induction as a diagnostic tool for community-acquired pneumonia in infants and young children from a high HIV prevalence area. Pediatr. Pulmonol. 2003; 36: 58-62.
66. Amadi B, Kelly P, Mwiya M et al. Intestinal and systemic infection, HIV, and mortality in Zambian children with persistent diarrhea and malnutrition. J. Pediatr. Gastroenterol. Nutr. 2001; 32: 550-4.
67. Amadi B, Mwiya M, Musuku J et al. Effect of nitazoxanide on morbidity and mortality in Zambian children with cryptosporidiosis: a randomised controlled trial. Lancet 2002; 360: 1375-80.
68. Tumwine JK, Kekitiinwa A, Nabukeera N et al. Cryptosporidium parvum in children with diarrhea in Mulago Hospital, Kampala, Uganda. Am. J. Trop. Med. Hyg. 2003; 68: 710-15.
69. Iqbal J, Munir MA, Khan MA. Cryptosporidium infection in young children with diarrhea in Rawalpindi, Pakistan. Am. J. Trop. Med. Hyg. 1999; 60: 868-70.
70. Agnew DG, Lima AA, Newman RD et al. Cryptosporidiosis in northeastern Brazilian children: association with increased diarrhea morbidity. J. Infect. Dis. 1998; 177: 754-60.
71. Checkley W, Epstein LD, Gilman RH, Black RE, Cabrera L, Sterling CR. Effects of Cryptosporidium parvum infection in Peruvian children: growth faltering and subsequent catch-up growth. Am. J. Epidemiol. 1998; 148: 497-506.
72. Guerrant RL. Cryptosporidiosis: an emerging, highly infectious threat. Emerg. Infect. Dis. 1997; 3: 51-7.
73. Molbak K, Andersen M, Aaby P et al. Cryptosporidium infection in infancy as a cause of malnutrition: a community study from Guinea-Bissau, west Africa. Am. J. Clin. Nutr. 1997; 65: 149-52.
74. Rossignol JF, Ayoub A, Ayers MS. Treatment of diarrhea caused by Cryptosporidium parvum: a prospective randomized, double-blind, placebo-controlled study of Nitazoxanide. J. Infect. Dis. 2001; 184: 103-6.
75. Graham SM. Impact of HIV on childhood respiratory illness: differences between developing and developed countries. Pediatr. Pulmonol. 2003; 36: 462-8.
76. Jahoor F, Abramson S, Heird WC. The protein metabolic response to HIV infection in young children. Am. J. Clin. Nutr. 2003; 78: 182-9.
77. Reid M, Badaloo A, Forrester T, Morlese JF, Heird WC, Jahoor F. The acute-phase protein response to infection in edematous and nonedematous protein-energy malnutrition. Am. J. Clin. Nutr. 2002; 76: 1409-15.
78. Kessler L, Daley H, Malenga G, Graham S. The impact of the human immunodeficiency virus type 1 on the management of severe malnutrition in Malawi. Ann. Trop. Paediatr. 2000; 20: 50-6.
79. Hendricks MK, Van Der BP, Parkin DP, Donald PR. Pharmacokinetics of amikacin in children with kwashiorkor. Ann. Trop. Paediatr. 1995; 15: 295-8.
80. Seifart HI, Donald PR, de Villiers JN, Parkin DP, Jaarsveld PP. Isoniazid elimination kinetics in children with protein-energy malnutrition treated for tuberculous meningitis with a four-component antimicrobial regimen. Ann. Trop. Paediatr. 1995; 15: 249-54.
81. Treluyer JM, Roux A, Mugnier C, Flouvat B, Lagardere B. Metabolism of quinine in children with global malnutrition. Pediatr. Res. 1996; 40: 558-63.
82. Lares Asseff I, Cravioto J, Santiago P, Perez Ortiz B. A new dosing regimen for metronidazole in malnourished children. Scand. J. Infect. Dis. 1993; 25: 115-21.
83. Lares-Asseff I, Cravioto J, Santiago P, Perez-Ortiz B. Pharmacokinetics of metronidazole in severely malnourished and nutritionally rehabilitated children. Clin. Pharmacol. Ther. 1992; 51: 42-50.
84. Heikens GT, Schofield WN, Christie CD, Gernay J, Dawson S. The Kingston Project. III. The effects of high energy supplement and metronidazole on malnourished children rehabilitated in the community: morbidity and growth. Eur. J. Clin. Nutr. 1993; 47: 174-91.
85. Heikens GT, Schofield WN, Dawson S. The Kingston Project. II. The effects of high energy supplement and metronidazole on malnourished children rehabilitated in the community: anthropometry. Eur. J. Clin. Nutr. 1993; 47: 160-73.
86. Haque R, Faruque AS, Hahn P, Lyerly DM, Petri WA Jr. Entamoeba histolytica and Entamoeba dispar infection in children in Bangladesh. J. Infect. Dis. 1997; 175: 734-6.
87. Braga LL, Gomes ML, Da Silva MW, Facanha FE Jr, Fiuza L, Mann BJ. Household epidemiology of Entamoeba histolytica infection in an urban community in northeastern Brazil. Am. J. Trop. Med. Hyg. 2001; 65: 268-71.
88. Brewster DR. Intestinal Permeability and Kwashiorkor in Malawi. Australia: University of Newcastle, 1996.
89. de la Morena ML, Van R, Singh K, Brian M, Murray ME, Pickering LK. Diarrhea associated with Aeromonas species in children in day care centers. J. Infect. Dis. 1993; 168: 215-18.
90. Pickering LK, Woodward WE, DuPont HL, Sullivan P. Occurrence of Giardia lamblia in children in day care centers. J. Pediatr. 1984; 104: 522-6.
91. Pickering LK, Bartlett AV, Woodward WE. Acute infectious diarrhea among children in day care: epidemiology and control. Rev. Infect. Dis. 1986; 8: 539-47.
92. Rauch AM, Van R, Bartlett AV, Pickering LK. Longitudinal study of Giardia lamblia infection in a day care center population. Pediatr. Infect. Dis. J. 1990; 9: 186-9.
93. Skull SA, Morris PS, Yonovitz A et al. Middle ear effusion: rate and risk factors in Australian children attending day care. Epidemiol. Infect. 1999; 123: 57-64.
94. Ashworth A, Chopra M, McCoy D et al. WHO guidelines for management of severe malnutrition in rural South African hospitals: effect on case fatality and the influence of operational factors. Lancet 2004; 363: 1110-15.
95. Puoane T, Sanders D, Chopra M et al. Evaluating the clinical management of severely malnourished children - a study of two rural district hospitals. S. Afr. Med. J. 2001; 91: 137-41.
96. Wilkinson D, Scrace M, Boyd N. Reduction in in-hospital mortality of children with malnutrition. J. Trop. Pediatr. 1996; 42: 114-15.
97. Osier FH, Berkley JA, Ross A, Sanderson F, Mohammed S, Newton CR. Abnormal blood glucose concentrations on admission to a rural Kenyan district hospital: prevalence and outcome. Arch. Dis. Child. 2003; 88: 621-5.
98. Solomon T, Felix JM, Samuel M et al. Hypoglycaemia in paediatric admissions in Mozambique. Lancet 1994; 343: 149-50.
99. Sandhu BK, Isolauri E, Walker-Smith JA et al. A multicentre study on behalf of the European Society of Paediatric Gastroenterology and Nutrition Working Group on Acute Diarrhoea. Early feeding in childhood gastroenteritis. J. Pediatr. Gastroenterol. Nutr. 1997; 24: 522-7.
100. Sandhu BK. Rationale for early feeding in childhood gastroenteritis. J. Pediatr. Gastroenterol. Nutr. 2001; 33 (4 Suppl.): S13-16.
101. Sandhu BK. Practical guidelines for the management of gastroenteritis in children. J. Pediatr. Gastroenterol. Nutr. 2001; 33 (4 Suppl.): S36-9.
102. Walker-Smith JA, Sandhu BK, Isolauri E et al. Guidelines prepared by the ESPGAN Working Group on Acute Diarrhoea. Recommendations for feeding in childhood gastroenteritis. European Society of Pediatric Gastroenterology and Nutrition. J. Pediatr. Gastroenterol. Nutr. 1997; 24: 619-20.
103. Whitehead RG. Dietary allowances: what to recommend. Acta Paediatr. Scand. Suppl. 1991; 373: 25-32.
104. Manary MJ, Hart CA, Whyte MP. Severe hypophosphatemia in children with kwashiorkor is associated with increased mortality. J. Pediatr. 1998; 133: 789-91.
105. Manary MJ, Brewster DR, Broadhead R et al. Whole-body protein kinetics in children with kwashiorkor and infection: a comparison of egg white and milk as dietary sources of protein. Am. J. Clin. Nutr. 1997; 66: 643-8.
106. Grantham-McGregor SM, Walker SP, Chang S. Nutritional deficiencies and later behavioural development. Proc. Nutr. Soc. 2000; 59: 47-54.
107. Dobbing J. Boyd Orr memorial lecture. Early nutrition and later achievement. Proc. Nutr. Soc. 1990; 49: 103-18.
108. Elizabeth KE, Sathy N. The role of developmental stimulation in nutritional rehabilitation. Indian Pediatr. 1997; 34: 681-95.
109. Baker-Henningham H, Powell C, Walker S, Grantham-McGregor S. Mothers of undernourished Jamaican children have poorer psychosocial functioning and this is associated with stimulation provided in the home. Eur. J. Clin. Nutr. 2003; 57: 786-92.
110. Fernald LC, Grantham-McGregor SM. Growth retardation is associated with changes in the stress response system and behavior in school-aged Jamaican children. J. Nutr. 2002; 132: 3674-9.
111. Golden M, Samuels MP, Southall DP. How to distinguish between neglect and deprivational abuse. Arch. Dis. Child. 2003; 88: 105-7.
112. Idohou-Dossou N, Wade S, Guiro AT et al. Nutritional status of preschool Senegalese children: long-term effects of early severe malnutrition. Br. J. Nutr. 2003; 90: 1123-32.
113. Skull SA, Ruben AR, Walker A. Malnutrition and microcephaly in Australian Aboriginal children. Med. J. Aust. 1997; 166: 412-14.