Contribution of villous atrophy to reduced intestinal maltase in infants with malnutrition

Journal of Pediatric Gastroenterology and Nutrition

Volumn 30, Issue 5, 2000, Pages 494-502

  Nichols, Buford L ^a   Nichols, Veda N ^a   Putman, Margaret ^a   Avery, Stephen E ^a   Fraley, J Kennard ^a   Quaroni, Andrea ^b   Shiner, Margot ^c   Sterchi, Erwin E ^d   Carrazza, Francisco R ^e  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

^d UNIVERSITY OF BERN   (Switzerland)

^e UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Glucose transporter mismatch; Maltase glucoamylase; Marasmic malnutrition; Starch hydrolysis; Villous atrophy

Indexed keywords

ALPHA GLUCOSIDASE; DISACCHARIDE; GLUCOSE TRANSPORTER; MESSENGER RNA; STARCH;

ARTICLE; CLINICAL ARTICLE; DIET; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; HUMAN; HYDROLYSIS; INFANT; INTESTINE BIOPSY; INTESTINE VILLUS ATROPHY; MALE; MALNUTRITION; MARASMUS; PATHOGENESIS; PRIORITY JOURNAL; QUANTITATIVE ASSAY;

ACTINS; ALPHA-GLUCOSIDASES; ATROPHY; BIOPSY; CARRIER PROTEINS; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INTESTINAL MUCOSA; INTESTINES; MALE; MEMBRANE GLYCOPROTEINS; MICROFILAMENT PROTEINS; MONOSACCHARIDE TRANSPORT PROTEINS; NUTRITION DISORDERS; NUTRITIONAL STATUS; RNA, MESSENGER; SODIUM-GLUCOSE TRANSPORTER 1;

EID: 0034084907     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005176-200005000-00007     Document Type: Article

References (77)

1. Nichols BL, Dudley MA, Nichols VN, et al. Effects of malnutrition on expression and activity of lactase in children. Gastroenterology 1997;112:742-51.
2. Nichols BL, Eldering J, Avery S, et al. Human small intestinal maltase-glucoamylase cDNA cloning: Homology to sucrase-isomaltase. J Biol Chem 1998;273:3076-81.
3. Brewster DR, Manary MJ, Menzies IS, et al. Comparison of milk and maize based diets in kwashiorkor. Arch Dis Child 1997;76: 242-8.
4. Christian M, Edwards C, Weaver LT. Starch digestion in infancy. J Pediatr Gastroenterol Nutr 1999;29:116-24.
5. Semenza G, Auricchio S. Small-intestinal disaccharidases. Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic Basis of Inherited Disease. New York: McGraw-Hill, 1989:2975-97.
6. Thillainayagam AV, Hunt JB, Farthing MJ. Enhancing clinical efficacy of oral rehydration therapy: Is low osmolality the key? Gastroenterology 1998;114:197-210.
7. Brown KH. Complementary feeding in developing countries: Factors affecting energy intake. Proc Nutr Soc 1997;56:139-48.
8. Heymann H, Breitmeyer D, Gunther S. Human small intestinal sucrase-isomaltase: Different binding patterns for malto- and isomalto-oligosaccharides. Biol Chem Hoppe-Seyler 1995;376:249-53.
9. Heymann H, Gunther S. Calculation of subsite affinities of human small intestinal glucoamylase. Biol Chem Hoppe-Sevler 1994;375: 451-5.
10. Papenheimer JR. On the coupling of membrane digestion with the intestinal absorption of sugars and amino acids. Am J Physiol 1993;265:G409-17.
11. Sevenhuysen GP, Holodinsky C,. Dawes C. Development of salivary-amylase in infants from birth to 5 months. Am J Clin Nutr 1984;39:584-8.
12. Lebenthal E, Lee PC. Development of functional response in human exocrine pancreas. Pediatrics 1980;66:556-60.
13. Barbezat GO, Hansen JDL. The exocrine pancreas and protein-calorie malnutrition. Pediatrics 1968;42:77-92.
14. Danus O, Urbina AM, Valenzuela I, Solimano G. The effect of refeeding on pancreatic exocrine function in marasmic infants. J Pediatr 1970;77:334-7.
15. Shirazi-Beechey SP. Intestinal sodium-dependent D-glucose transporter: Dietary regulation. Proc Nutr Soc 1996;55:167-78.
16. Ferraris RP, Diamond JM. Specific regulation of intestinal nutrient transporters by their dietary substrates. Ann Rev Physiol 1989;51: 125-41.
17. Galluser M, Belkhou R, Freund J-N, et al. Adaption of intestinal hydrolases to starvation in rats: Effect of thyroid function. J Comp Physiol Series B Biol Sci 1991;161:357-61.
18. Pond WG, Ellis KJ, Mersmann HJ, et al. Severe protein deficiency and repletion alter body and brain and organ weights in infant pigs. J Nutr 1996;126:290-302.
19. Lebenthal E, U KM, Zheng BY, et al. Small intestinal glucoamylase deficiency and starch malabsorption: A newly recognized alpha-glucosidase deficiency in children. J Pediatr 1994;124:541-6.
20. Martin MG, Lostoa MP, Turk E, et al. Compound missense mutations in sodium/D-glucose cotransporter (SGLT 1) results in trafficking defects. Gastroenterology 1997;112:1206-12.
21. Klish WJ, Udall JN, Rodriguez JT, et al. Intestinal surface area in infants with acquired monosaccharide intolerance. J Pediatr 1978; 92:566-71.
22. Shiner M, Putman M, Nichols VN, Nichols BL. Pathogenesis of small-intestinal mucosal lesions in chronic diarrhea of infancy: I. A light microscopic study. J Pediatr Gastroenterol Nutr 1990;11: 455-63.
23. Calvin RT, Klish WJ, Nichols BL. Disaccharidase activities, jejunal morphology, and carbohydrate tolerance in children with chronic diarrhea. J Pediatr Gastroenterol Nutr 1985;4:949-53.
24. Nichols BL, Carrazza F, Nichols VN, et al. Mosaic expression of brush border enzymes in infants with chronic diarrhea and malnutrition. J Pediatr Gastroenterol Nutr 1992;14:371-9.
25. Wang Y, Harvey C, Rousset M, et al. Expression of human intestinal mRNA transcripts during development: Analysis by a semi-quantitative RNA polymerase chain reaction method. Pediatr Res 1994;36:514-21.
26. Fajardo O, Naim HY, Lacey SW. The polymorphic expression of lactase in adults is regulated at the messenger RNA level. Gastroenterology 1994;106:1233-41.
27. James WPT. Effects of protein-calorie malnutrition on intestinal absorption. Ann NY Acad Sci 1971;176:244-61.
28. James WPT. Sugar absorption and intestinal motility in children when malnourished and after treatment. Clin Sci 1970;39:305-18.
29. James WPT. Intestinal absorption in protein-calorie malnutrition. Lancet 1968;2:333-5.
30. James WPT. Jejunal disaccharidase activities in children with marasmus and with kwashiorkor: Response to treatment. Arch Dis Child 1971;46:218-20.
31. James WPT. Comparison of three methods used in assessment of carbohydrate absorption in malnourished children. Arch Dis Child 1972;47:531-6.
32. Stanfield PJ. The small intestine in protein energy malnutrition. In: Creamer B, ed. The Small Intestine. Chicago: William Heinemann Medical Books Publication, 1974:247-59.
33. Cevini G, Giovanni M, Careddu P. Alterazioni della digestione e dell'assorbimento intestinale dei glucidi nei disturbi acuti e cronici della nutrizione del lattante. Minerva Pediatr 1962;14:831-5.
34. Bowie MD, Brinkman GL, Hansen JDL. Diarrhoea in protein-calorie malnutrition. Lancet 1963;2:550-1.
35. Bowie MD, Brinkman GL, Hansen JDL. Acquired disaccharide intolerance in malnutrition. Pediatrics 1965;66:1083-91.
36. Bowie MD, Barbezat GO, Hansen JDL. Carbohydrate absorption in malnourished children. Am J Clin Nutr 1967;89-97.
37. Kerpel-Fronius E, Jani L, Fekete M. Disaccharide malabsorption in different types of malnutrition. Ann Pediatr 1966;206:245-57.
38. Wharton B, Howells G, Phillip I. Diarrhoea in kwashiorkor. BMJ 1968;4:608-11.
39. Prinsloo JG, Wittmann W, Pretorius PJ, et al. Effect of different sugars on diarrhoea of acute kwashiorkor. Arch Dis Child 1969; 44:593-9.
40. Brasseur D, Hennart P, Vis HL. Malabsorption of intact lactose. Lancet 1985;2:100-01.
41. Brasseur D, Vis HL. L'activite lactaseique de labordure en brosse de l'enterocyte. Acta Gastroenterol Belg 1984;46:115-22.
42. Nordio S, Lamedica GM, Berio A, et al. Disaccharidase activities of duodenal mucosa in children. Ann Paediatr 1966;206:287-312.
43. Cook GC, Lee FD. The jejunum after kwashiorkor. Lancet 1966; 2:1263-7.
44. DeLarrechea I, Ibarra R, Sampayo RR, et al. Malabsorption in malnutrition [abstract]. Gastroenterology 1967;52:1103.
45. Prinsloo JG, Wittmann W, Kruger H, et al. Lactose absorption and mucosal disaccharidases in convalescent pellagra and kwashiorkor children. Arch Dis Child 1971;46:474-8.
46. Romer H, Urbach R, Gomez MA, et al. Moderate and severe protein energy malnutrition in childhood: Effects on jejunal mucosal morphology and disaccharidase activities. J Pediatr Gastroenterol Nutr 1983;2:459-64.
47. Sokucu S. Enterokinase and disaccharidase activities of the small intestinal mucosa in infants with protein energy malnutrition and in normal infants. Turk J Pediatr 1987;29:15-24.
48. Burman D. The jejunal mucosa in kwashiorkor. Arch Dis Child 1965;40:526-31.
49. Stanfield JP, Hutt MSR, Tunnicliffe R. Intestinal biopsy in kwashiorkor. 1965;2:519-23.
50. Cook GC, Lee FD. The jejunum after kwashiorkor. Lancet 1966; 2:1263-7.
51. Brunser O, Reid A, Monckeberg F, et al. Jejunal biopsies in infant malnutrition: With special reference to mitotic index. Pediatrics 1966;38:605-12.
52. Barbezat GO. Gastrointestinal studies in human protein-calorie malnutrition [abstract]. S Afr Med J 1967;41:1211.
53. Barbezat GO, Bowie MD, Kaschula ROC, et al. Studies on the small intestinal mucosa of children with protein-calorie malnutrition. S Afr Med J 1967;41:1031-6.
54. Nunez-Montiel O, Bauza CA, Brunser O, et al. Ultrastructural variations of the jejunum in the malabsorption syndrome. Lab Invest 1967;12:16-24.
55. Tandon BN, Magotra ML, Saraya AK, et al. Small intestine in protein malnutrition. Am J Clin Nutr 1968;21:813-9.
56. Brunser O, Reid A, Monckeberg F, et al. Jejunal mucosa in infant malnutrition. Am J Clin Nutr 1968;21:976-83.
57. Berkel I, Kiran O, Say B. Jejunal mucosa in infantile malnutrition. Acta Paediatr Scand 1970;59:58-64.
58. Theron JJ, Wittmann W, Prinsloo JG. The fine structure of the jejunum in kwashiorkor. Exp Mol Pathol 1971;58:184-99.
59. Schneider RE, Viteri FE. Morphological aspects of the duodenojejunal mucosa in protein-calorie malnourished children and during recovery. Am J Clin Nutr 1972;25:1092-102.
60. Mayoral LG, Tripathy K, Bolanos O, et al. Intestinal, functional, and morphologic abnormal in severely protein-malnourished adults. Am J Clin Nutr 1972;25:1084-91.
61. Shiner M, Redmond AOB, Hansen JDL. The jejunal mucosa in protein-energy malnutrition: A clinical, histological, and ultrastructural study. Exp Mol Pathol 1973;19:61-78.
62. Duque E, Bolanos O, Lotero H, Mayoral LG. Enteropathy in adult protein malnutrition: Light microscopic findings. Am J Clin Nutr 1975;28:901-13.
63. Duque E, Lotero H, Bolanos O, Mayoral LG. Enteropathy in adult protein malnutrition: Ultrastructural findings. Am J Clin Nutr 1975;28:914-24.
64. Brunser O, Castillo C, Araya M. Fine structure of the small intestinal mucosa in infantile marasmic malnutrition. Gastroenterology 1976;70:495-507.
65. Neto UF, Wehba J, Patricio FRS, et al. Morphological and functional study of the small intestine in marasmic patients. Arq Gastroenterol 1977;14:241-8.
66. Kaschula ROC, Fajjar PD, Mann M, et al. Infantile jejunal mucosa in infection and malnutrition. Isr J Med Sci 1979;15:356-61.
67. Nassar AM, El Tantawy SA, Khalifa S, et al. Ultrastructural changes in the mucosa of the small intestine due to protein-calorie malnutrition. J Trop Pediatr 1980;26:62-72.
68. Zoppi G, Hadorn B, Gitzelmann R, Kistler H, Prader A. Intestinal-galactosidase activities in malabsorption syndromes. Gastroenterology 1966;50:557-61.
69. Desjeux JF, Sassier P, Tichet J, et al. Sugar absorption by flat jejunal mucosa. Acta Pediatr Scand 1973;62:531-7.
70. Berg NO, Dahlqvist A, Lindberg T, et al. Correlation between morphological alterations and enzyme activities in the mucosa of the small intestine. Scand J Gastroenterol 1973;8:703-12.
71. Lebenthal E, Antonowicz I, Schwachman H. The interrelationship of enterokinase and trypsin activities in intractable diarrhea of infancy, celiac disease, and intravenous alimentation. Pediatrics 1975;56:585-91.
72. Welch JD, Poley JR, Bhatia M, et al. Intestinal disaccharidase activities in relation to age, race, and mucosal damage. Gastroenterology 1978;75:847-55.
73. Harrison M, Walker-Smith JA. Reinvestigation of lactose intolerant children: Lack of correlation between continuing lactose intolerance and small intestinal morphology, disaccharidase activity, and lactose tolerance tests. Gut 1977;18:48-52.
74. Lebenthal E, Lee PC. Glucoamylase and disaccharidase activities in normal subjects and in patients with mucosal injury of the small intestine. J Pediatr 1980;97:389-93.
75. Rossi TM, Lebenthal E, Nord KS, et al. Extent and duration of small intestinal mucosal injury in intractable diarrhea of infancy. Pediatrics 1980;66:730-5.
76. Shulman RJ, Langston C, Lifschitz CH. Histologic findings are not correlated with disaccharidase activities in infants with protracted diarrhea. J Pediatr Gastroenterol Nutr 1991;12:70-5.
77. Louvard D. The function of the major cytoskeletal components of the brush border. Curr Opin Cell Biol 1989;1:51-7.