Nucleotides bind to the C-terminus of ClC-5

Biochemical Journal

Volumn 398, Issue 2, 2006, Pages 289-294

  Wellhauser, Leigh ^a,b   Kuo, Hsin Hen ^a,b   Stratford, Fiona L L ^a   Ramjeesingh, Mohabir ^a   Huan, Ling Jun ^a   Luong, Winnie ^a,b   Li, Canhui ^a,b   Deber, Charles M ^a,b   Bear, Christine E ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

CD; Chloride channel 5 (ClC 5); Chloride ion channel; Cystathionine synthase; Nucleotide; Protein purification

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOCHEMISTRY; DISEASE CONTROL; DISEASES; GENETIC ENGINEERING; MUTAGENESIS;

CHLORIDE CHANNEL 5 (CLC-5); CHLORIDE ION CHANNEL; CYSTATHIONINE Β-SYNTHASE; NUCLEOTIDES; PROTEIN PURIFICATION;

CELL MEMBRANES;

CHLORIDE CHANNEL; CYSTATHIONINE; ION CHANNEL; NUCLEOTIDE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; RECOMBINANT PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EUKARYOTIC CELL; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; KIDNEY DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEINURIA; CHEMISTRY; CIRCULAR DICHROISM; GENETICS; HYDROLYSIS; ISOLATION AND PURIFICATION; METABOLISM; PROTEIN DENATURATION; PROTEIN SECONDARY STRUCTURE; TEMPERATURE;

EUKARYOTA;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; CHLORIDE CHANNELS; CIRCULAR DICHROISM; GENE EXPRESSION; HUMANS; HYDROLYSIS; PROTEIN DENATURATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; TEMPERATURE;

EID: 33748373612     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060142     Document Type: Article

References (30)

1. Thakker, R. V. (1999) Chloride channels in renal disease. Adv. Nephrol. Necker Hosp. 29, 289-298
2. George, Jr, A. L. (1998) Chloride channels and endocytosis: ClC-5 makes a dent. Proc. Natl. Acad. Sci. U.S.A. 95, 7843-7845
3. Jentsch, T. J. (2005) Chloride transport in the kidney: lessons from human disease and knockout mice. J. Am. Soc. Nephrol. 16, 1549-1561
4. Christensen, E. I., Devuyst, O., Dom, G., Nielsen, R., Van der Smissen, P., Verroust, P., Leruth, M., Guggino, W. B. and Courtoy, P. J. (2003) Loss of chloride channel ClC-5 impairs endocytosis by defective trafficking of megalin and cubilin in kidney proximal tubules. Proc. Natl. Acad. Sci. U.S.A. 100, 8472-8477
5. --channel disruption impairs endocytosis in a mouse model for Dent's disease. Nature (London) 408, 369-373
6. Hara-Chikuma, M., Wang, Y., Guggino, S. E., Guggino, W. B. and Verkman, A. S. (2005) Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochem. Biophys. Res. Commun. 329, 941-946
7. Gunther, W., Piwon, N. and Jentsch, T. J. (2003) The ClC-5 chloride channel knock-out mouse - an animal model for Dent's disease. Pflugers Arch. 445, 456-462
8. Mohammad-Panah, R., Harrison, R., Dhani, S., Ackerley, C., Huan, L. J., Wang, Y. and Bear, C. E. (2003) The chloride channel ClC-4 contributes to endosomal acidification and trafficking. J. Biol. Chem. 278, 29267-29277
9. van Weert, A. W., Dunn, K. W., Gueze, H. J., Maxfield, F. R. and Stoorvogel, W. (1995) Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump. J. Cell Biol. 130, 821-834
10. Jentsch, T. J., Neagoe, I. and Scheel, O. (2005) CLC chloride channels and transporters. Curr. Opin. Neurobiol. 15, 319-325
11. Dutzler, R., Campbell, E. B., Cadene, M., Chait, B. T. and MacKinnon, R. (2002) X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature (London) 415, 287-294
12. Jordt, S. E. and Jentsch, T. J. (1997) Molecular dissection of gating in the ClC-2 chloride channel. EMBO J. 16, 1582-1592
13. Estevez, R., Pusch, M., Ferrer-Costa, C., Orozco, M. and Jentsch, T. J. (2004) Functional and structural conservation of CBS domains from CLC chloride channels. J. Physiol. 557, 363-378
14. Hebeisen, S. and Fahlke, C. (2005) Carboxy-terminal truncations modify the outer pore vestibule of muscle chloride channels. Biophys. J. 89, 1710-1720
15. Denton, J., Nehrke, K., Yin, X., Beld, A. and Strange, K. (2005) Altered gating and regulation of a carboxy-terminus ClC channel mutant expressed in the C. elegans oocyte. Am. J. Physiol. Cell Physiol. 290, C1109-C1118
16. Ignoul, S. and Eggermont, J. (2005) CBS domains: structure, function, and pathology in human proteins. Am. J. Physiol. Cell Physiol. 289, C1369-C1378
17. Meyer, S. and Dutzler, R. (2006) Crystal structure of the cytoplasmic domain of the chloride channel ClC-0. Structure 14, 299-307
18. Scott, J. W., Hawley, S. A., Green, K. A., Anis, M., Stewart, G., Scullion, G. A., Norman, D. G. and Hardie, D.G. (2004) CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations. J. Clin. Invest. 113, 274-284
19. Bennetts, B., Rychkov, G. Y., Ng, H. L., Morton, C. J., Stapleton, D., Parker, M. W. and Cromer, B. A. (2005) Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels. J. Biol. Chem. 280, 32452-32458
20. Niemeyer, M. I., Yusef, Y. R., Cornejo, I., Flores, C. A., Sepulveda, F. V. and Cid, L. P. (2004) Functional evaluation of human ClC-2 chloride channel mutations associated with idiopathic generalized epilepsies. Physiol. Genomics 19, 74-83
21. Vanoye, C. G. and George, Jr, A. L. (2002) Functional characterization of recombinant human ClC-4 chloride channels in cultured mammalian cells. J. Physiol. 539, 373-383
22. Kogan, I., Ramjeesingh, M., Li, C. and Bear, C. E. (2002) Studies of the molecular basis for cystic fibrosis using purified reconstituted CFTR protein. Methods Mol. Med. 70, 143-157
23. Maduke, M., Williams, C. and Miller, C. (1998) Formation of CLC-0 chloride channels from separated transmembrane and cytoplasmic domains. Biochemistry 37, 1315-1321
24. Li, C., Ramjeesingh, M., Wang, W., Garami, E., Hewryk, M., Lee, D., Rommens, J. M., Galley, K. and Bear, C. E. (1996) ATPase activity of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 271, 28463-28468
25. Ramjeesingh, M., Li, C., Garami, E., Huan, L. J., Galley, K., Wang, Y. and Bear, C. E. (1999) Walker mutations reveal loose relationship between catalytic and channel-gating activities of purified CFTR (cystic fibrosis transmembrane conductance regulator). Biochemistry 38, 1463-1468
26. Argos, P., Rossman, M. G., Grau, U. M., Zuber, H., Frank, G. and Tratschin, J. D. (1979) Thermal stability and protein structure. Biochemistry 18, 5698-5703
27. Picollo, A. and Pusch, M. (2005) Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5. Nature (London) 436, 420-423
28. Scheel, O., Zdebik, A. A., Lourdel, S. and Jentsch, T. J. (2005) Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins. Nature (London) 436, 424-427
29. van Weert, A. W., Geuze, H. J., Groothuis, B. and Stoorvogel, W. (2000) Primaquine interferes with membrane recycling from endosomes to the plasma membrane through a direct interaction with endosomes which does not involve neutralisation of endosomal pH nor osmotic swelling of endosomes. Eur. J. Cell Biol. 79, 394-399
30. +-ATPase. Physiol. Rev. 84, 1263-1314