Implantable or external defibrillators for individuals at increased risk of cardiac arrest: Where cost-effectiveness hits fiscal reality

Value in Health

Volumn 9, Issue 5, 2006, Pages 292-302

  Cram, Peter ^a,g   Katz, David ^a,b   Vijan, Sandeep ^c,d   Kent, David M ^e   Langa, Kenneth M ^c,d   Fendrick, A Mark ^d,f  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e TUFTS MEDICAL CENTER   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

^g UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Cost effectiveness; Defibrillators; Emergency medical services; Heart arrest; Rationing

Indexed keywords

ARTICLE; COST EFFECTIVENESS ANALYSIS; DEFIBRILLATOR; ECONOMIC ASPECT; EMERGENCY WARD; HEART ARREST; HUMAN; MEDICAL SERVICE; MORTALITY; PRIORITY JOURNAL; PROBABILITY; QUALITY OF LIFE;

EID: 33748341070     PISSN: 10983015     EISSN: 15244733     Source Type: Journal    
DOI: 10.1111/j.1524-4733.2006.00118.x     Document Type: Article

References (86)

1. Berenson A. A cancer drug shows promise at a price that many can't pay. The New York Times, February 15, 2006:A1.
2. Ginsburg PB. Controlling health care costs. N Engl J Med 2004;351:1591-3.
3. Halvorson GC. Commentary - Current MSA theory: well-meaning but futile. Health Serv Res 2004;39(Pt 2):1119-22.
4. Robinson JC. Health savings accounts - the ownership society in health care. N Engl J Med 2005;353:1199-202.
5. Gillick MR. Medicare coverage for technological innovations - time for new criteria? N Engl J Med 2004;350:2199-203.
6. Heffler S, Smith S, Keehan S, et al. Health spending projections through 2013. Health Aff 2004;(Suppl. Web Exclusives):W4-79-93.
7. Calmes J. Elephant in the room: budget wish lists come and go but "entitlements" outweigh all. The Wall Street Journal February 3, 2006:1.
8. Moss AJ, Hall WJ, Cannom DS, et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med 1996;335:1933-40.
9. Buxton AE, Lee KL, Fisher JD, et al. A randomized study of the prevention of sudden death in patients with coronary artery disease. N Engl J Med 1999;341:1882-90.
10. Gold MR, Siegel JE, Russell LB, Weinstein MC, eds. Cost-Effectiveness in Health and Medicine. New York: Oxford University Press, 1996.
11. Moss AJ, Zareba W, Hall WJ, et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med 2002;346:877-83.
12. Bardy GH, Lee KL, Mark DB, et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med 2005;352:225-37.
13. Al-Khatib SM, Anstrom KJ, Eisenstein EL, et al. Clinical and economic implications of the multicenter automatic defibrillator implantation trial-II. Ann Intern Med 2005;142:593-600.
14. Sanders GD, Hlatky MA, Owens DK. Cost-effectiveness of implantable cardioverter-defibrillators. N Engl J Med 2005;353:1471-80.
15. McClellan MB, Tunis SR. Medicare coverage of ICDs. N Engl J Med 2005;352:222-4.
16. Valenzuela TD, Roe DJ, Nichol G, et al. Outcomes of rapid defibrillation by security officers after cardiac arrest in casinos. N Engl J Med 2000;343:1206-9.
17. Caffrey SL, Willoughby PJ, Pepe PE, Becker LB. Public use of automated external defibrillators. N Engl J Med 2002;347:1242-7.
18. Cram P, Vijan S, Katz D, Fendrick AM. Cost-effectiveness of in-home automated external defibrillators for individuals at increased risk of sudden cardiac death. J Gen Intern Med 2005;20:251-8.
19. Healthcare inflation index. http://www.cms.hhs.gov/statistics/health- indicators/t9.asp. [Accessed March 11, 2004.]
20. Greenberg H, Case RB, Moss AJ, et al. Analysis of mortality events in the multicenter automatic defibrillator implantation trial (MADIT-II)*1. J Am Coll Cardiol 2004;43:1459-65.
21. Hohnloser SH, Kuck KH, Dorian P, et al. Prophylactic use of an implantable cardioverter-defibrillator after acute myocardial infarction. N Engl J Med 2004;351:2481-8.
22. National Center for Health Statistics. United States Life Tables, 2001. 2001.
23. Stiell IG, Wells GA, Field BJ, et al. Improved out-of-hospital cardiac arrest survival through the inexpensive optimization of an existing defibrillation program: OPALS study phase II. Ontario Prehospital Advanced Life Support. JAMA 1999;281:1175-81.
24. Cobb LA, Fahrenbruch CE, Walsh TR, et al. Influence of cardiopulmonary resuscitation prior to defibrillation in patients with out-of-hospital ventricular fibrillation. JAMA 1999;281:1182-8.
25. Ladwig KH, Schoefinius A, Danner R, et al. Effects of early defibrillation by ambulance personnel on short- and long-term outcome of cardiac arrest survival: the Munich experiment. Chest 1997;112:1584-91.
26. Eisenberg MS, Horwood BT, Cummins RO, et al. Cardiac arrest and resuscitation: a tale of 29 cities. Ann Emerg Med 1990;19:179-86.
27. Becker LB, Ostrander MP, Barrett J, Kondos GT. Outcome of CPR in a large metropolitan area - where are the survivors? Ann Emerg Med 1991;20:355-61.
28. Stults KR, Brown DD, Schug VL, Bean JA. Prehospital defibrillation performed by emergency medical technicians in rural communities. N Engl J Med 1984;310:219-23.
29. Lombardi G, Gallagher J, Gennis P. Outcome of out-of-hospital cardiac arrest in New York City. The Pre-Hospital Arrest Survival Evaluation (PHASE) Study. JAMA 1994;271:678-83.
30. Valenzuela TD, Roe DJ, Cretin S, et al. Estimating effectiveness of cardiac arrest interventions: a logistic regression survival model. Circulation 1997;96:3308-13.
31. Larsen MP, Eisenberg MS, Cummins RO, Hallstrom AP. Predicting survival from out-of-hospital cardiac arrest: a graphic model. Ann Emerg Med 1993;22:1652-8.
32. Valenzuela TD, Spaite DW, Meislin HW, et al. Emergency vehicle intervals versus collapse-to-CPR and collapse-to-defibrillation intervals: monitoring emergency medical services system performance in sudden cardiac arrest. Ann Emerg Med 1993;22:1678-83.
33. Eisenberg MS. Is it time for over-the-counter defibrillators? JAMA 2000;284:1435-8.
34. Ornato JP, McNeill SE, Craren EJ, Nelson NM. Limitation on effectiveness of rapid defibrillation by emergency medical technicians in a rural setting. Ann Emerg Med 1984;13:1096-9.
35. Eisenberg MS, Mengert TJ. Cardiac resuscitation. N Engl J Med 2001;344:1304-13.
36. Weaver WD, Peberdy MA. Defibrillators in public places - one step closer to home. N Engl J Med 2002;347:1223-4.
37. Holmberg M, Holmberg S, Herlitz J. The problem of out-of-hospital cardiac-arrest prevalence of sudden death in Europe today. Am J Cardiol 1999;83:88D-90D.
38. The Public Access Defibrillation Trial Investigators. Public-access defibrillation and survival after out-of-hospital cardiac arrest. N Engl J Med 2004;351:637-46.
39. Bunch TJ, White RD, Gersh BJ, et al. Long-term outcomes of out-of-hospital cardiac arrest after successful early defibrillation. N Engl J Med 2003;348:2626-33.
40. The Hypothermia after Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002;346:549-56.
41. de Vos R, de Haes HCJM, Koster RW, de Haan RJ. Quality of survival after cardiopulmonary resuscitation. Arch Intern Med 1999;159:249-54.
42. Granja C, Cabral G, Pinto AT, Costa-Pereira A. Quality of life 6-months after cardiac arrest. Resuscitation 2002;55:37-44.
43. Sedgwick ML, Watson J, Dalziel K, et al. Efficacy of out of hospital defibrillation by ambulance technicians using automated external defibrillators. The Heartstart Scotland Project. Resuscitation 1992;24:73-87.
44. Connolly SJ, Hallstrom AP, Cappato R, et al. Meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. Eur Heart J 2000;21:2071-8.
45. Ezekowitz JA, Armstrong PW, McAlister FA. Implantable cardioverter defibrillators in primary and secondary prevention: a systematic review of randomized, controlled trials. Ann Intern Med 2003;138:445-52.
46. Hardie K, Hankey GJ, Jamrozik K, et al. Ten-year survival after first-ever stroke in the perth community stroke study. Stroke 2003;34:1842-6.
47. Rosenqvist M, Beyer T, Block M, et al. Adverse events with transvenous implantable cardioverter-defibrillators: a prospective multicenter study. Circulation 1998;98:663-70.
48. Kadish A, Dyer A, Daubert JP, et al. Prophylactic defibrillator implantation in patients with nonischemic dilated cardiomyopathy. N Engl J Med 2004;350:2151-8.
49. Mushlin AI, Hall WJ, Zwanziger J, et al. The cost-effectiveness of automatic implantable cardiac defibrillators: results from MADIT. Circulation 1998;97:2129-35.
50. Reiffel JA, Dizon J. Cardiology patient page. The implantable cardioverter-defibrillator: patient perspective. Circulation 2002;105:1022-4.
51. Chen L, Hay JW. Cost-effectiveness of primary implanted cardioverter defibrillator for sudden death prevention in congestive heart failure. Cardiovasc Drugs Ther 2004;18:161-70.
52. Ferguson TB Jr, Ferguson CL, Crites K, Crimmins-Reda P. The additional hospital costs generated in the management of complications of pacemaker and defibrillator implantations. J Thorac Cardiovasc Surg 1996;111:742-51;discussion 751-2.
53. Amiodarone Trials Meta-Analysis Investigators. Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in randomised trials. Lancet 1997;350:1417-24.
54. Sim I, McDonald KM, Lavori PW, et al. Quantitative overview of randomized trials of amiodarone to prevent sudden cardiac death. Circulation 1997;96:2823-9.
55. Stroupe KT, Teal EY, Weiner M, et al. Health care and medication costs and use among older adults with heart failure. Am J Med 2004;116:443-50.
56. Sanders GD, Hlatky MA, Every NR, et al. Potential cost-effectiveness of prophylactic use of the implantable cardioverter defibrillator or amiodarone after myocardial infarction. Ann Intern Med 2001;135:870-83.
57. Owens DK, Sanders GD, Harris RA, et al. Cost-effectiveness of implantable cardioverter defibrillators relative to amiodarone for prevention of sudden cardiac death. Ann Intern Med 1997;126:1-12.
58. Kuppermann M, Luce BR, McGovern B, et al. An analysis of the cost effectiveness of the implantable defibrillator. Circulation 1990;81:91-100.
59. Larsen G, Hallstrom A, McAnulty J, et al. Cost-effectiveness of the implantable cardioverter-defibrillator versus antiarrhythmic drugs in survivors of serious ventricular tachyarrhythmias: results of the antiarrhythmics versus implantable defibrillators (AVID) economic analysis substudy. Circulation 2002;105:2049-57.
60. Weiss JP, Saynina O, McDonald KM, et al. Effectiveness and cost-effectiveness of implantable cardioverter defibrillators in the treatment of ventricular arrhythmias among medicare beneficiaries. Am J Med 2002;112:519-27.
61. Groeneveld PW, Kwong JL, Liu Y, et al. Cost-effectiveness of automated external defibrillators on airlines. JAMA 2001;286:1482-9.
62. Nichol G, Hallstrom AP, Ornato JP, et al. Potential cost-effectiveness of public access defibrillation in the United States. Circulation 1998;97:1315-20.
63. Taylor TN, Davis PH, Torner JC, et al. Lifetime cost of stroke in the United States. Stroke 1996;27:1459-66.
64. Tsevat J, Goldman L, Soukup JR, et al. Stability of time-tradeoff utilities in survivors of myocardial infarction. Med Decis Making 1993;13:161-5.
65. Fryback DG, Dasbach EJ, Klein R, et al. The Beaver Dam Health Outcomes Study: initial catalog of health-state quality factors. Med Decis Making 1993;13:89-102.
66. Vlay SC. The automatic internal cardioverter-defibrillator: comprehensive clinical follow-up, economic and social impact - the Stony Brook experience. Am Heart J 1986;112:189-94.
67. Pycha C, Gulledge AD, Hutzler J, et al. Psychological responses to the implantable defibrillator: preliminary observations. Psychosomatics 1986;27:841-5.
68. Nichol G, Stiell IG, Hebert P, et al. What is the quality of life for survivors of cardiac arrest? A prospective study. Acad Emerg Med 1999;6:95-102.
69. Gage BF, Cardinalli AB, Owens DK. The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life. Arch Intern Med 1996;156:1829-36.
70. Samsa GP, Matchar DB, Williams GR, Levy DE. Cost-effectiveness of ancrod treatment of acute ischaemic stroke: results from the Stroke Treatment with Ancrod Trial (STAT). J Eval Clin Prac 2002;8:61-70.
71. Doubilet P, Begg CB, Weinstein MC, et al. Probabilistic sensitivity analysis using Monte Carlo simulation. Med Decis Making 1985;5:157-77.
72. Pasta DJ, Taylor JL, Henning JM. Probabilistic sensitivity analysis incorporating the bootstrap. an example comparing treatments for the eradication of Helicobacter pylori. Med Decis Making 1999;19:353-63.
73. Kent DM, Fendrick AM, Langa KM. New and disimproved. on the evaluation and use of less effective, less expensive medical interventions. Med Decis Making 2004;24:281-6.
74. Neumann PJ. Why don't Americans use cost-effectiveness analysis? Am J Manag Care 2004;10:308-12.
75. Coleman B, McChesney S, Twaddle B. Does the priority scoring system for joint replacement really identify those in most need? N Z Med J 2005; 118:U1463.
76. Carlsen B, Norheim OF. "Saying no is no easy matter" a qualitative study of competing concerns in rationing decisions in general practice. BMC Health Serv Res 2005;5:70.
77. Tunis SR. Why medicare has not established criteria for coverage decisions. N Engl J Med 2004;350:2196-8.
78. Lindholm LH, Dahlof B, Edelman JM, et al. Effect of losartan on sudden cardiac death in people with diabetes: data from the LIFE study. Lancet 2003;362:619-20.
79. Fendrick AM, Smith DG, Chernew ME, Shah SN. A benefit-based copay for prescription drugs: patient contribution based on total benefits, not drug acquisition cost. [see comment]. Am J Manag Care 2001;7:861-7.
80. Jorgenson DB, Skarr T, Russell JK, et al. AED use in businesses, public facilities and homes by minimally trained first responders. Resuscitation 2003;59:225-33.
81. Pereira J. For the fearful: portable defibrillator. The Wall Street Journal September 1, 1999:1.
82. Cram P, Vijan S, Wolbrink A, Fendrick AM. The impact of including passive benefits in cost-effectiveness analysis: the case of automated external defibrillators on commercial aircraft. Value Health 2003;6:466-73.
83. Goldman L. Cost-effectiveness in a flat world - can ICDs help the United States get rhythm? N Engl J Med 2005;353:1513-15.
84. Burton TM. A hard choice for heart patients. The Wall Street Journal October 12, 2005:D1.
85. Meier B. F.D.A. had report of short circuit in heart devices. The New York Times October 20, 2005:A4.
86. Huikuri HV, Tapanainen JM, Lindgren K, et al. Prediction of sudden cardiac death after myocardial infarction in the beta-blocking era. [see comment]. J Am Coll Cardiol 2003;42:652-8.