Cost-effectiveness of in-home automated external defibrillators for individuals at increased risk of sudden cardiac death: There's no place like home?

Journal of General Internal Medicine

Volumn 20, Issue 3, 2005, Pages 251-258

  Cram, Peter ^a,f   Vijan, Sandeep ^b,c   Katz, David ^a,d   Fendrick, A Mark ^b,e  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF IOWA   (United States)

^e UNIVERSITY OF MICHIGAN   (United States)

^f UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Defibrillators; Emergency medical services; Heart arrest

Indexed keywords

ADULT; ARTICLE; AUTOMATION; CARDIOMYOPATHY; CARDIOVASCULAR RISK; COHORT ANALYSIS; COST BENEFIT ANALYSIS; COST EFFECTIVENESS ANALYSIS; DEFIBRILLATOR; HEART ARREST; HEART INFARCTION; HOME CARE; HUMAN; MAJOR CLINICAL STUDY; PROBABILITY; QUALITY ADJUSTED LIFE YEAR; RISK ASSESSMENT; SUDDEN DEATH; SURVIVAL RATE;

COST-BENEFIT ANALYSIS; DEATH, SUDDEN, CARDIAC; DECISION SUPPORT TECHNIQUES; DEFIBRILLATORS; EMERGENCY MEDICAL SERVICES; HOME CARE SERVICES; HUMANS; LIFE EXPECTANCY; MARKOV CHAINS; MONTE CARLO METHOD; QUALITY-ADJUSTED LIFE YEARS; RISK FACTORS; UNITED STATES;

EID: 18244383766     PISSN: 08848734     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1525-1497.2005.40247.x     Document Type: Article

References (76)

1. Zheng ZJ, Croft JB, Giles WH, Mensah GA. Sudden cardiac death in the United States, 1989 to 1998. Circulation. 2001;104:2158-63.
2. Guidelines 2000 for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2000;102(suppl):1-370.
3. A comparison of antiarrhythmic-drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. The Antiarrhythmics Versus Implantable Defibrillators (AVID) Investigators. N Engl J Med. 1997;337:1576-83.
4. Moss AJ, Hall WJ, Cannom DS, et al. Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med. 1996;335:1933-40.
5. Moss AJ, Zareba W, Hall WJ, et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346:877-83.
6. Ezekowitz JA, Armstrong PW, McAlister FA. Implantable cardioverter defibrillators in primary and secondary prevention: a systematic review of randomized, controlled trials. Ann Intern Med. 2003;138:445-52.
7. Myerburg RJ, Interian A Jr, Mitrani RM, Kessler KM, Castellanos A. Frequency of sudden cardiac death and profiles of risk. Am J Cardiol. 1997;80:10F-19F.
8. Huikuri HV, Tapanainen JM, Lindgren K, et al. Prediction of sudden cardiac death after myocardial infarction in the beta-blocking era. Am Coll Cardiol. 2003;42:652-8.
9. Goldenberg I, Jonas M, Tenenbaum A, et al. Current smoking, smoking cessation, and the risk of sudden cardiac death in patients with coronary artery disease. Arch Intern Med. 2003;163:2301-5.
10. Gillum RF. Sudden coronary death in the United States: 1980-1985. Circulation. 1989;79:756-65.
11. Cobb LA, Fahrenbruch CE, Walsh TR, et al. Influence of cardiopulmonary resuscitation prior to defibrillation in patients with out-of-hospital ventricular fibrillation. JAMA. 1999;281:1182-8.
12. Ladwig KH, Schoefinius A, Danner R, et al. Effects of early defibrillation by ambulance personnel on short-and long-term outcome of cardiac arrest survival: the Munich experiment. Chest. 1997;112:1584-91.
13. Stiell IG, Wells GA, Field BJ, et al. Improved out-of-hospital cardiac arrest survival through the inexpensive optimization of an existing defibrillation program: Opals study phase II. Ontario prehospital advanced life support. JAMA. 1999;281:1175-81.
14. Lombardi G, Gallagher J, Gennis P. Outcome of out-of-hospital cardiac arrest in New York City. The pre-hospital arrest survival evaluation (phase) study. JAMA. 1994;271:678-83.
15. Weaver WD, Peberdy MA. Defibrillators in public places - one step closer to home. N Engl J Med. 2002;347:1223-4.
16. Cram P, Vijan S, Fendrick AM. Cost-effectiveness of automated external defibrillator deployment in selected public locations. J Gen Intern Med. 2003;18:745-54.
17. The Public Access Defibrillation Trial Investigators. Public-access defibrillation and survival after out-of-hospital cardiac arrest. N Engl J Med. 2004;351:637-46.
18. Caffrey SL, Willoughby PJ, Pepe PE, Becker LB. Public use of automated external defibrillators. N Engl J Med. 2002;347:1242-7.
19. Valenzuela TD, Roe DJ, Nichol G, Clark LL, Spaite DW, Hardman RG. Outcomes of rapid defibrillation by security officers after cardiac arrest in casinos. N Engl J Med. 2000;343:1206-9.
20. Eisenberg MS. Is it time for over-the-counter defibrillators? JAMA. 2000;284:1435-8.
21. Ornato JP, McNeill SE, Craren EJ, Nelson NM. Limitation on effectiveness of rapid defibrillation by emergency medical technicians in a rural setting. Ann Emerg Med. 1984;13:1096-9.
22. Eisenberg MS, Mengert TJ. Cardiac resuscitation. N Engl J Med. 2001;344:1304-13.
23. Moore JE, Eisenberg MS, Andresen E, Cummins RO, Hallstrom A, Litwin P. Home placement of automatic external defibrillators among survivors of ventricular fibrillation. Ann Emerg Med. 1986;15:811-2.
24. Lee TH. A shock at home can save a life. For some people, it makes sense to have an automated external defibrillator at home. Harv Heart Lett. 2003;13:6-7.
25. Rosenberg D. Home defibrillators - taking technology to heart: a portable defibrillator in every home? The Wall Street Journal. March 31. 2003:R13.
26. Kissel M. Taking doctors' orders out of defibrillators. The Wall Street Journal. July 26, 2004:B1.
27. National Center for Health Statistics. United States life tables, 2001. Available at: http://www.cdc.gov/nchs/data/nvsr/nvsr52/nvsr52_14.pdf. Accessed July 27, 2004.
28. Lindholm LH, Ibsen H, Dahlof B, et al. Cardiovascular morbidity and mortality in patients with diabetes in the losartan intervention for end-point reduction in hypertension study (life): a randomised trial against atenolol. Lancet. 2002;359:1004-10.
29. Myerburg RJ, Kessler KM, Castellanos A. Sudden cardiac death. Structure, function, and time-dependence of risk. Circulation. 1992;85(suppl):I2-I10.
30. Lindholm LH, Dahlof B, Edelman JM, et al. Effect of losartan on sudden cardiac death in people with diabetes: data from the life study. Lancet. 2003;362:619-20.
31. Haider AW, Larson MG, Benjamin EJ, Levy D. Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death. J Am Coll Cardiol. 1998;32:1454-9.
32. Lloyd-Jones DM, Camargo CA, Allen LA, Giugliano RP, O'Donnell CJ. Predictors of long-term mortality after hospitalization for primary unstable angina pectoris and non-ST-elevation myocardial infarction. Am J Cardiol. 2003;92:1155-9.
33. Chang WC, Kaul P, Westerhout CM, et al. Impact of sex on long-term mortality from acute myocardial infarction vs unstable angina. Arch Intern Med. 2003;163:2476-84.
34. Goldberg RJ, Yarzebski J, Lessard D, Gore JM. A two-decades (1975 to 1995) long experience in the incidence, in-hospital and long-term case-fatality rates of acute myocardial infarction: a community-wide perspective. J Am Coll Cardiol. 1999;33:1533-9.
35. Josephson ME, Callans DJ, Buxton AE. The role of the implantable cardioverter-defibrillator for prevention of sudden cardiac death. Ann Intern Med. 2000;133:901-10.
36. Greenberg H, Case RB, Moss AJ, Brown MW, Carroll ER, Andrews ML. Analysis of mortality events in the multicenter automatic defibrillator implantation trial. J Am Coll Cardiol. 2004;43:1459-65.
37. Sanders GD, Hlatky MA, Every NR, et al. Potential cost-effectiveness of prophylactic use of the implantable cardioverter defibrillator or amiodarone after myocardial infarction. Ann Intern Med. 2001;135:870-83.
38. Beck JR, Kassirer JP, Pauker SG. A convenient approximation of life expectancy. Validation of the method. Am J Med. 1982;73:883-8.
39. Holmberg M, Holmberg S, Herlitz J. The problem of out-of-hospital cardiac-arrest prevalence of sudden death in Europe today. Am J Cardiol. 1999;83:88D-90D.
40. Callahan CM, Stump TE, Stroupe KT, Tierney WM. Cost of health care for a community of older adults in an urban academic healthcare system. J Am Geriatr Soc. 1998;46:1371-7.
41. Ackermann RT, Cheadle A, Sandhu N, Madsen L, Wagner EH, LoGerfo JP. Community exercise program use and changes in healthcare costs for older adults. Am J Prev Med. 2003;25:232-7.
42. Ciechanowski PS, Katon WJ, Russo JE. Depression and diabetes: impact of depressive symptoms on adherence, function, and costs. Arch Intern Med. 2000;160:3278-85.
43. Eisenstein EL, Shaw LK, Anstrom KJ, et al. Assessing the clinical and economic burden of coronary artery disease: 1986-1998. Med Care. 2001;39:824-35.
44. Stroupe KT, Teal EY, Weiner M, Gradus-Pizlo I, Brater DC, Murray MD. Health care and medication costs and use among older adults with heart failure. Am J Med. 2004;116:443-50.
45. Philips HeartStart home defibrillator. Available at: http://www.heart- starthome.com/content/heartstart_home.asp. Accessed April 21, 2004.
46. Groeneveld PW, Kwong JL, Liu Y, et al. Cost-effectiveness of automated external defibrillators on airlines. JAMA. 2001;286:1482-9.
47. Bureau of Labor Statistics average wage report. Available at: http://www.bls.gov/ncs/ocs/sp/ncb10539.pdf. Accessed April 15, 2004.
48. Mushlin AI, Hall WJ, Zwanziger J, et al. The cost-effectiveness of automatic implantable cardiac defibrillators: results from MADIT. Circulation. 1998;97:2129-35.
49. Larsen G, Hallstrom A, McAnulty J, et al. Cost-effectiveness of the implantable cardioverter-defibrillator versus antiarrhythmic drugs in survivors of serious ventricular tachyarrhythmias: results of the antiarrhythmics versus implantable defibrillators (AVID) economic analysis substudy. Circulation. 2002;105:2049-57.
50. Weiss JP, Saynina O, McDonald KM, McClellan MB, Hlatky MA. Effectiveness and cost-effectiveness of implantable cardioverter defibrillators in the treatment of ventricular arrhythmias among Medicare beneficiaries. Am J Med. 2002;112:519-27.
51. Nichol G, Hallstrom AP, Ornato JP, et al. Potential cost-effectiveness of public access defibrillation in the United States. Circulation. 1998;97:1315-20.
52. Healthcare inflation index. Available at: http://www.cms.hhs.gov/ statistics/health-indicators/t9.asp. Accessed March 11, 2004.
53. Gold MR, Siegel JE, Russell LB, Weinstein MC, eds. Cost-effectiveness in Health and Medicine. New York, NY: Oxford University Press; 1996.
54. Eisenberg MS, Horwood BT, Cummins RO, Reynolds-Haertle R, Hearne TR. Cardiac arrest and resuscitation: a tale of 29 cities. Ann Emerg Med. 1990;19:179-86.
55. Becker LB, Ostrander MP, Barrett J, Kondos GT. Outcome of CPR in a large metropolitan area - where are the survivors? Ann Emerg Med. 1991;20:355-61.
56. Stults KR, Brown DD, Schug VL, Bean JA. Prehospital defibrillation performed by emergency medical technicians in rural communities. N Engl J Med. 1984;310:219-23.
57. Valenzuela TD, Roe DJ, Cretin S, Spaite DW, Larsen MP. Estimating effectiveness of cardiac arrest interventions: a logistic regression survival model. Circulation. 1997;96:3308-13.
58. Larsen MP, Eisenberg MS, Cummins RO, Hallstrom AP. Predicting survival from out-of-hospital cardiac arrest: a graphic model. Ann Emerg Med. 1993;22:1652-8.
59. Valenzuela TD, Spaite DW, Meislin HW, Clark LL, Wright AL, Ewy GA. Emergency vehicle intervals versus collapse-to-CPR and collapse-to- defibrillation intervals: monitoring emergency medical services system performance in sudden cardiac arrest. Ann Emerg Med. 1993;22:1678-83.
60. Bunch TJ, White RD, Gersh BJ, et al. Long-term outcomes of out-of-hospital cardiac arrest after successful early defibrillation. N Engl J Med. 2003;348:2626-33.
61. Kuilman M, Bleeker JK, Hartman JA. Simoons ML. Long-term survival after out-of-hospital cardiac arrest: an 8-year follow-up. Resuscitation. 1999;41:25-31.
62. Connoliy SJ, Hallstrom AP, Cappato R, et al. Meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. Eur Heart J. 2000;21:2071-8.
63. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002;346:549-56.
64. de Vos R, de Haes HCJM, Koster RW, de Haan RJ. Quality of survival after cardiopulmonary resuscitation. Arch Intern Med. 1999;159:249-54.
65. Granja C, Cabral G, Pinto AT, Costa-Pereira A. Quality of life 6-months after cardiac arrest. Resuscitation. 2002;55:37-44.
66. Sedgwick ML, Watson J, Dalziel K, Carrington DJ, Cobbe SM. Efficacy of out of hospital defibrillation by ambulance technicians using automated external defibrillators. The HeartStart Scotland Project. Resuscitation. 1992;24:73-87.
67. Nichol G, Stiell IG, Hebert P, Wells GA, Vandemheen K, Laupacis A. What is the quality of life for survivors of cardiac arrest? A prospective study. Acad Emerg Med. 1999;6:95-102.
68. Gage BF, Cardinalli AB, Owens DK. The effect of stroke and stroke prophylaxis with aspirin or warfarin on quality of life. Arch Intern Med. 1996;156:1829-36.
69. Doubilet P, Begg CB, Weinstein MC, Braun P, McNeil BJ. Probabilistic sensitivity analysis using Monte Carlo simulation. Med Decis Making. 1985;5:157-77.
70. Hirth R, Chernew M, Miller E, Fendrick A, Weissert W. Willingness to pay for a quality-adjusted life year: in search of a standard. Med Decis Making. 2000;20:332-42.
71. Ubel PA, Hirth RA, Chernew ME, Fendrick AM. What is the price of life and why doesn't it increase at the rate of inflation? Arch Intern Med. 2003;163:1637-41.
72. Bailey JJ, Berson AS, Handelsman H, Hodges M. Utility of current risk stratification tests for predicting major arrhythmic events after myocardial infarction. J Am Coll Cardiol. 2001;38:1902-11.
73. Jorgenson DB, Skarr T, Russell JK, Snyder DE, Uhrbrock K. AED use in businesses, public facilities and homes by minimally trained first responders. Resuscitation. 2003;59:225-33.
74. Cram P, Vijan S, Wolbrink A, Fendrick AM. The impact of including passive benefits in cost-effectiveness analysis: the case of automated external defibrillators on commercial aircraft. Value in Health. 2003;6:466-73.
75. Wassertheil J, Keane G, Fisher N, Leditschke JF. Cardiac arrest outcomes at the Melbourne Cricket Ground and Shrine of Remembrance using a tiered response strategy - a forerunner to public access defibrillation. Resuscitation. 2000;44:97-104.
76. Page RL, Joglar JA, Kowal RC, et al. Use of automated external defibrillators by a U.S. airline. N Engl J Med. 2000;343:1210-6.