Sustained release formulation of erythropoietin using hyaluronic acid hydrogels crosslinked by Michael addition

International Journal of Pharmaceutics

Volumn 322, Issue 1-2, 2006, Pages 44-51

  Hahn, Sei Kwang ^a   Oh, Eun Ju ^a   Miyamoto, Hajime ^b   Shimobouji, Tsuyoshi ^b  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Erythropoietin; Hyaluronic acid; Hydrogel; Michael addition; Sustained release

Indexed keywords

ACETONITRILE; ADIPIC ACID; ALCOHOL; DIMETHYL SULFOXIDE; DITHIOTHREITOL; ERYTHROPOIETIN; HYALURONIC ACID; HYALURONIDASE; MACROGOL DERIVATIVE; METHACRYLIC ACID; TRIETHANOLAMINE; TRIFLUOROACETIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DRUG BLOOD LEVEL; GELATION; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MICHAEL ADDITION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SUSTAINED RELEASE FORMULATION;

ANIMALS; CROSS-LINKING REAGENTS; DELAYED-ACTION PREPARATIONS; DITHIOTHREITOL; DRUG CARRIERS; ERYTHROPOIETIN; HYALURONIC ACID; HYDROGELS; METHACRYLATES; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33748335675     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.05.024     Document Type: Article

References (30)

1. Balazs E.A., and Denlinger J.L. Viscosupplementation: a new concept in the treatment of osteoarthritis. J. Rheumatol. 20 (1993) 3-9
2. Balazs, E.A., Leshchiner, A., 1987. Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues. US patent no. 4713448.
3. Balazs, E.A., Leshchiner, A., 1986. Cross-linked gels of hyaluronic acid and products containing such gels. US patent no. 4582865.
4. Balazs E.A. Sodium hyaluronate and viscosurgery. In: Miller D., and Stegmann R. (Eds). Healon (sodium hyaluronate). A guide to its use in Ophthalmic Surgery (1983), Wiley, New York 5-28
5. Bulpitt P., and Aeschlimann D. New strategy for chemical modification of hyaluronic acid: preparation of functionalized derivatives and their use in the formation of novel biocompatible hydrogels. J. Biomed. Mater. Res. 47 (1999) 152-169
6. Campoccia D., Doherty P., Radice M., Brun P., Abatangelo G., and Williams D.F. Semisynthetic resorbable materials from hyaluronan esterification. Biomaterials 19 (1998) 2101-2117
7. Carr, D., 2002. The handbook of analysis and purification of peptides and proteins by reversed-phase HPLC, third ed. http://www.gracevydac.com.
8. Chowdhury S.M., and Hubbell J.A. Adhesion prevention with ancrod released via a tissue adherent hydrogel. J. Surg. Res. 61 (1996) 58-64
9. Elbert D.L., Pratt A.B., Lutolf M.P., Halstenberg S., and Hubbell J.A. Protein delivery from materials formed by self-selective conjugate addition reactions. J. Control. Release 76 (2001) 11-25
10. Fahrner R.L., Lester P.M., Blank G.S., and Reifsnyder D.H. Non-flammable preparative reversed-phase liquid chromatography of recombinant human insulin-like growth factor-I. J. Chromatogr. A 830 (1999) 127-134
11. Ferraiolo B.L., Mohler M.A., and Gloff C.A. Protein Pharmacokinetics and Metabolism (1992), Plenum Press, New York
12. Fu K., Klibanov A.M., and Langer R. Protein stability in controlled-release systems. Nat. Biotechnol. 18 (2000) 24-25
13. Hahn S.K., Kim S.J., Kim M.J., and Kim D.H. Characterization and in vivo study of sustained release formulation of human growth hormone using sodium hyaluronate. Pharm. Res. 21 (2004) 1374-1381
14. Hahn S.K., Jelacic S., Maier R.V., Stayton P.S., and Hoffman A.S. Anti-inflammatory drug delivery from hyaluronic acid hydrogels. J. Biomater. Sci. Polym. 15 (2004) 1111-1119
15. Hermanson G.T. Bioconjugate Techniques (1996), Academic Press pp. 131
16. Hermentin P., Witzel R., Schwick-Wagner P., and Blumrich M. N-glycan charge assay: an alternative for potency assays of therapeutic glycoproteins?. Dev. Biol. (Basel) 111 (2002) 89-97
17. Jones A.J., Putney S., Johnson O.L., and Cleland J.L. Recombinant human growth hormone poly(lactic-co-glycolic acid) microsphere formulation development. Adv. Drug Deliver. Rev. 28 (1997) 71-83
18. Kim S.J., Hahn S.K., Kim M.J., Kim D.H., and Lee Y.P. Development of a novel sustained release formulation of recombinant human growth hormone using sodium hyaluronate microparticles. J. Control. Release 104 (2005) 323-335
19. Kuo J.W., Swann D.A., and Prestwich G.D. Chemical modification of hyaluronic acid by carbodiimides. Bioconjugate Chem. 2 (1991) 232-241
20. Laurent T.C. The Chemistry Biology and Medical Applications of Hyaluronan and its Derivatives vol. 72 (1998), Portland Press, London Wenner-Gren International Series
21. Leach J.B., and Schmidt C.E. Characterization of protein release from photocrosslinkable hyaluronic acid-polyethylene glycol hydrogel tissue engineering scaffolds. Biomaterials 26 (2005) 125-135
22. Luo Y., Kirker K., and Prestwich G. Cross-linked hyaluronic acid hydrogel films: new biomaterials for drug delivery. J. Control. Release 69 (2000) 169-184
23. Lutolf M.P., Tirelli N., Cerritelli S., Cavalli L., and Hubbell J.A. Systematic modulation of Michael-type reactivity of thiols through the use of charged amino acids. Bioconjugate Chem. 12 (2001) 1051-1056
24. Marchetti M., and Barosi G. Clinical and economic impact of Epoetins in cancer care. Pharmacoeconomics 22 (2004) 1029-1045
25. Ohri R., Hahn S.K., Stayton P.S., Hoffman A.S., and Giachelli M. Hyaluronic acid grafting mitigates calcification of glutaraldhyde-fixed bovine pericardium. J. Biomed. Mater. Res. 70A (2004) 159-165
26. Pouyani T., and Prestwich G.D. Functionalized derivatives of hyaluronic acid oligosaccharides: drug carriers and novel biomaterials. Bioconjugate Chem. 5 (1994) 339-347
27. Shu X.Z., Liu Y., Palumbo F.S., Luo Y., and Prestwich G.D. In situ crosslinkable hyaluronan hydrogels for tissue engineering. Biomaterials 25 (2004) 1339-1348
28. Vercruysse K.P., and Prestwich G.D. Hyaluronate derivatives in drug delivery. Crit. Rev. Ther. Carrier Syst. 15 (1998) 513-555
29. West D.C., Hampson I.N., Arnold F., and Kumar S. Angiogenesis induced by degradation products of hyaluronic acid. Science 228 (1985) 1324-1326
30. Wilczynska J.D., Roman I., and Anuszewska E. The separation of EPO from other proteins in medical products formulated with different stabilizers. Acta Polym. Pharm. 62 (2005) 177-182