The first total synthesis of (±)-annosqualine by means of oxidative enamide-phenol coupling: pronounced effect of phenoxide formation on the phenol oxidation mechanism

Tetrahedron Letters

Volumn 47, Issue 41, 2006, Pages 7301-7306

  Shigehisa, Hiroki ^a   Takayama, Jun ^a   Honda, Toshio ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Annosqualine; Enamide phenol coupling; Iodobenzene diacetate; Phenoxide formation; Spiro isoquinoline alkaloid

Indexed keywords

1 METHYL 1,2,3,4 TETRAHYDROISOQUINOLINE DERIVATIVE; ANNOSQUALINE; ENAMINE; HYDROXYL GROUP; IODINE; ISOQUINOLINE DERIVATIVE; PHENOL; PHENOXIDE; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CHEMICAL STRUCTURE; DESILYLATION; OXIDATION; OXIDATIVE STRESS; POLYMERIZATION; REACTION ANALYSIS; SPECTROSCOPY; SYNTHESIS;

EID: 33748331441     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2006.08.028     Document Type: Article

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