Development and validation of a fluorescence HPLC-based screening assay for inhibition of human estrogen sulfotransferase

Analytical Biochemistry

Volumn 357, Issue 1, 2006, Pages 85-92

  Reinen, Jelle ^a   Vriese, Eveline ^a   Glatt, Hansruedi ^b   Vermeulen, Nico P E ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

1 Hydroxypyrene; Endocrine disruption; Pyrene 1 sulfate; Substrate inhibition; SULT1E1 inhibition

Indexed keywords

ENDOCRINOLOGY; ENZYME KINETICS; FLAVONOIDS; KINETIC THEORY; METABOLITES; PYRENE; SUBSTRATES;

1-HYDROXYPYRENE; ENDOCRINE DISRUPTING COMPOUND; ENDOCRINE DISRUPTION; ESTROGENIC EFFECT; NON-MICHAELIS-MENTEN KINETICS; PERIPHERAL TISSUE; RADIOLABELED SUBSTRATES; SUBSTRATE INHIBITION;

ENDOCRINE DISRUPTERS;

1 HYDROXYPYRENE; 17ALPHA ESTRADIOL; 4,4' ISOPROPYLIDENEDIPHENOL; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; BIPHENYLDIOL; COUMAROL; DIELDRIN; DIENESTROL; DIETHYLSTILBESTROL; ENDOCRINE DISRUPTOR; ENDRIN; ESTRADIOL; ESTRIOL; ESTROGEN SULFOTRANSFERASE; ESTRONE; ETHINYLESTRADIOL; GENISTEIN; HEXESTROL; METHOXYCHLOR; NONYLPHENOL; PROGESTERONE; PYRENE; PYRENE 1 SULFATE; SULFATE; SULFUR 35; UNCLASSIFIED DRUG; ZEARALENONE;

ARTICLE; CALIBRATION; CELL PROLIFERATION; DNA SYNTHESIS; ENZYME INHIBITION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME SUBSTRATE; ESTROGEN ACTIVITY; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; ISOTOPE LABELING; MICHAELIS MENTEN KINETICS; MOLECULAR CLONING; PRIORITY JOURNAL; TISSUE SPECIFICITY; VALIDATION PROCESS; XENOBIOTIC METABOLISM;

EID: 33748310918     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.07.015     Document Type: Article

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