Crystal structure of α-amino-β-carboxymuconate-ε- semialdeliyde decarboxylase: Insight into the active site and catalytic mechanism of a novel decarboxylation reaction

Biochemistry

Volumn 45, Issue 35, 2006, Pages 10412-10421

  Martynowski, Dariusz ^a   Eyobo, Yvonne ^a   Li, Tingfeng ^b   Yang, Kun ^a   Liu, Aimin ^b   Zhang, Hong ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; BIOSYNTHESIS; CATALYSIS; CONFORMATIONS; CRYSTAL STRUCTURE; ENZYMES; HYDROGEN BONDS; METABOLISM;

CITRIC ACID CYCLE; EUKARYOTIC ORGANISMS; PSEUDOMONAS FLUORESCENS; QUINOLINIC ACID;

ENZYME KINETICS;

2 NITROBENZOIC ACID; ACETYL COENZYME A; ADENOSINE DEAMINASE; ALPHA AMINO BETA CARBOXYMUCONATE EPSILON SEMIALDEHYDE DECARBOXYLASE; ARGININE; BENZOIC ACID DERIVATIVE; CARBOXYLYASE; COBALT; CYTOSINE DEAMINASE; HISTIDINE; IRON; NICOTINAMIDE ADENINE DINUCLEOTIDE; QUINOLINIC ACID; TRYPTOPHAN; UNCLASSIFIED DRUG; ZINC;

ALPHA CHAIN; ARTICLE; BETA CHAIN; BINDING SITE; CATALYSIS; CITRIC ACID CYCLE; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PSEUDOMONAS FLUORESCENS;

BINDING SITES; CARBOXY-LYASES; CATALYSIS; COENZYMES; CRYSTALLOGRAPHY, X-RAY; DECARBOXYLATION; METALS; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; PSEUDOMONAS FLUORESCENS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

BACTERIA (MICROORGANISMS); EUKARYOTA; PSEUDOMONAS FLUORESCENS;

EID: 33748250307     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060903q     Document Type: Article

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