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Volumn 48, Issue 5, 2006, Pages 509-519

Functional characterization and epitope analysis of a recombinant dermonecrotic protein from Loxosceles intermedia spider

Author keywords

Epitope mapping; Loxosceles venom; Recombinant dermonecrotic protein; Synthetic peptides

Indexed keywords

COMPLEMENT; EPITOPE; PEPTIDE; RECOMBINANT PROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE; VENOM;

EID: 33748172799     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.06.019     Document Type: Article
Times cited : (45)

References (31)
  • 1
    • 1642452868 scopus 로고    scopus 로고
    • Production of monoclonal antibodies capable of neutralizing dermonecrotic activity of Loxosceles intermedia spider venom and their use in a specific immunometric assay
    • Alvarenga L.M., Martins M.S., Moura J.F., Kalapothakis E., Oliveira J.C., Mangili O.C., Granier C., and Chávez-Olórtegui C. Production of monoclonal antibodies capable of neutralizing dermonecrotic activity of Loxosceles intermedia spider venom and their use in a specific immunometric assay. Toxicon 42 (2003) 725-731
    • (2003) Toxicon , vol.42 , pp. 725-731
    • Alvarenga, L.M.1    Martins, M.S.2    Moura, J.F.3    Kalapothakis, E.4    Oliveira, J.C.5    Mangili, O.C.6    Granier, C.7    Chávez-Olórtegui, C.8
  • 2
    • 0037353548 scopus 로고    scopus 로고
    • Protection against dermonecrotic and lethal activities of Loxosceles intermedia spider venom by immunization with a fused recombinant protein
    • Araújo S.C., Castanheira P., Magalhães L.A., Mangili O.C., Kalaphotakis E., and Chávez-Olortegui C. Protection against dermonecrotic and lethal activities of Loxosceles intermedia spider venom by immunization with a fused recombinant protein. Toxicon 41 (2003) 261-267
    • (2003) Toxicon , vol.41 , pp. 261-267
    • Araújo, S.C.1    Castanheira, P.2    Magalhães, L.A.3    Mangili, O.C.4    Kalaphotakis, E.5    Chávez-Olortegui, C.6
  • 3
    • 0026050417 scopus 로고
    • In vivo protection against scorpion toxins by liposomal immunization
    • Chavez-Olortegui C., Amaral D.A., Rochat H., Diniz C., and Granier C. In vivo protection against scorpion toxins by liposomal immunization. Vaccine 9 12 (1991) 907-910
    • (1991) Vaccine , vol.9 , Issue.12 , pp. 907-910
    • Chavez-Olortegui, C.1    Amaral, D.A.2    Rochat, H.3    Diniz, C.4    Granier, C.5
  • 4
    • 0028670626 scopus 로고
    • ELISA for the detection of toxic antigens in experimental and clinical envenoming by Tityus serrulatus scorpion venom
    • Chavez-Olortegui C., Fonseca S.C., Campolina D., Amaral C.F., and Diniz CR. ELISA for the detection of toxic antigens in experimental and clinical envenoming by Tityus serrulatus scorpion venom. Toxicon 32 12 (1994) 1649-1656
    • (1994) Toxicon , vol.32 , Issue.12 , pp. 1649-1656
    • Chavez-Olortegui, C.1    Fonseca, S.C.2    Campolina, D.3    Amaral, C.F.4    Diniz, CR.5
  • 5
    • 0032496177 scopus 로고    scopus 로고
    • ELISA for the detection of venom antigens in experimental and clinical envenoming by Loxosceles intermedia spiders
    • Chavez-Olortegui C., Zanetti V.C., Ferreira A.P., Minozzo J.C., Mangili O.C., and Gubert I.C. ELISA for the detection of venom antigens in experimental and clinical envenoming by Loxosceles intermedia spiders. Toxicon 36 (1998) 563-569
    • (1998) Toxicon , vol.36 , pp. 563-569
    • Chavez-Olortegui, C.1    Zanetti, V.C.2    Ferreira, A.P.3    Minozzo, J.C.4    Mangili, O.C.5    Gubert, I.C.6
  • 6
    • 1642574226 scopus 로고    scopus 로고
    • Purification and characterization of loxnecrogin, a dermonecrotic toxin from Loxosceles gaucho brown spider venom
    • Cunha R.B., Barbaro K.C., Muramatsu D., Portaro F.C., Fontes W., and de Sousa M.V. Purification and characterization of loxnecrogin, a dermonecrotic toxin from Loxosceles gaucho brown spider venom. J. Protein Chem. 22 2 (2003) 135-146
    • (2003) J. Protein Chem. , vol.22 , Issue.2 , pp. 135-146
    • Cunha, R.B.1    Barbaro, K.C.2    Muramatsu, D.3    Portaro, F.C.4    Fontes, W.5    de Sousa, M.V.6
  • 9
    • 0342359205 scopus 로고    scopus 로고
    • Action of metalloproteinases Mutalysin I and II on several components of the hemostatic and fibrinolytic systems
    • Estevao-Costa M.I., Diniz C.R., Magalhaes A., Markland F.S., and Sanchez E.F. Action of metalloproteinases Mutalysin I and II on several components of the hemostatic and fibrinolytic systems. Thromb. Res. 99 4 (2000) 363-376
    • (2000) Thromb. Res. , vol.99 , Issue.4 , pp. 363-376
    • Estevao-Costa, M.I.1    Diniz, C.R.2    Magalhaes, A.3    Markland, F.S.4    Sanchez, E.F.5
  • 10
    • 0032125173 scopus 로고    scopus 로고
    • Detection and characterization of gelatinolytic, fibronectinolytic snd fibrinogenolytic activities in Brown Spider (Loxosceles intermedia) Venom
    • Feitosa L., Gremski W., Veiga S.S., Elias M.C.Q.B., Graner E., Mangili O.C., and Brentani R.R. Detection and characterization of gelatinolytic, fibronectinolytic snd fibrinogenolytic activities in Brown Spider (Loxosceles intermedia) Venom. Toxicon 36 (1998) 1039-1051
    • (1998) Toxicon , vol.36 , pp. 1039-1051
    • Feitosa, L.1    Gremski, W.2    Veiga, S.S.3    Elias, M.C.Q.B.4    Graner, E.5    Mangili, O.C.6    Brentani, R.R.7
  • 12
    • 0026656122 scopus 로고
    • Spot-synthesis: an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support
    • Frank R. Spot-synthesis: an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support. Tetrahedron 48 (1992) 9217-9232
    • (1992) Tetrahedron , vol.48 , pp. 9217-9232
    • Frank, R.1
  • 13
    • 0012779241 scopus 로고
    • Observação dos efeitos do veneno Loxoscélico e avaliação de sua atividade
    • Furlanetto R.S., Bürchel W., Rosa R.R., Saliba F., and Navas J. Observação dos efeitos do veneno Loxoscélico e avaliação de sua atividade. Ciênc. Cul. 14 (1962) 254
    • (1962) Ciênc. Cul. , vol.14 , pp. 254
    • Furlanetto, R.S.1    Bürchel, W.2    Rosa, R.R.3    Saliba, F.4    Navas, J.5
  • 15
    • 0018180520 scopus 로고
    • A spectrophotometric method for determination of sphingomyelinase, Biochim
    • Gatt S., Dinur T., and Barenholz Y. A spectrophotometric method for determination of sphingomyelinase, Biochim. Biophys. Acta 530 (1978) 503-507
    • (1978) Biophys. Acta , vol.530 , pp. 503-507
    • Gatt, S.1    Dinur, T.2    Barenholz, Y.3
  • 16
    • 0033991720 scopus 로고    scopus 로고
    • Induction of neutralizing antibodies against Tityus serrulatus toxins by immunization with a recombinant non-toxic protein
    • Guatimosim S.C.F., Kalapothakis E., Diniz C.R., and Chávez-Olórtegui C. Induction of neutralizing antibodies against Tityus serrulatus toxins by immunization with a recombinant non-toxic protein. Toxicon 38 1 (2000) 113-121
    • (2000) Toxicon , vol.38 , Issue.1 , pp. 113-121
    • Guatimosim, S.C.F.1    Kalapothakis, E.2    Diniz, C.R.3    Chávez-Olórtegui, C.4
  • 17
    • 0031473847 scopus 로고    scopus 로고
    • SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling
    • Guex N., and Peitsch M.C. SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling. Electrophoresis 18 15 (1997) 2714-2723
    • (1997) Electrophoresis , vol.18 , Issue.15 , pp. 2714-2723
    • Guex, N.1    Peitsch, M.C.2
  • 18
    • 0036891354 scopus 로고    scopus 로고
    • Molecular cloning, expression and immunological properties of Lid1, a protein from the dermonecrotic family of Loxosceles intermedia spider venom
    • Kalapothakis E., Araujo S.C., Castro C.S., Gomez M.V., Mangili O.C., Gubert I.C., Diniz C.R., and Chávez-Olórtegui C. Molecular cloning, expression and immunological properties of Lid1, a protein from the dermonecrotic family of Loxosceles intermedia spider venom. Toxicon 40 (2002) 1691-1699
    • (2002) Toxicon , vol.40 , pp. 1691-1699
    • Kalapothakis, E.1    Araujo, S.C.2    Castro, C.S.3    Gomez, M.V.4    Mangili, O.C.5    Gubert, I.C.6    Diniz, C.R.7    Chávez-Olórtegui, C.8
  • 19
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227 (1970) 680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 20
    • 0036721676 scopus 로고    scopus 로고
    • Application of the spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding
    • Laune D., Molina F., Ferrieres G., Villard S., Bes C., Rieunier F., Chardes T., and Granier C. Application of the spot method to the identification of peptides and amino acids from the antibody paratope that contribute to antigen binding. J. Immunol. Methods 267 (2002) 53-70
    • (2002) J. Immunol. Methods , vol.267 , pp. 53-70
    • Laune, D.1    Molina, F.2    Ferrieres, G.3    Villard, S.4    Bes, C.5    Rieunier, F.6    Chardes, T.7    Granier, C.8
  • 22
    • 33748188186 scopus 로고    scopus 로고
    • Ministério Da Saúde Do Brasil. 1998. Manual de diagnóstico e tratamento de acidentes por animais peçonhentos. Brasília, Fundação Nacional De Saúde.
  • 23
    • 17144386576 scopus 로고    scopus 로고
    • Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D
    • Murakami M.T., Fernandes-Pedrosa M.F., Tambourgi D.V., and Arni R.K. Structural basis for metal ion coordination and the catalytic mechanism of sphingomyelinases D. J. Biol. Chem. 280 14 (2005) 13658-13664
    • (2005) J. Biol. Chem. , vol.280 , Issue.14 , pp. 13658-13664
    • Murakami, M.T.1    Fernandes-Pedrosa, M.F.2    Tambourgi, D.V.3    Arni, R.K.4
  • 27
    • 0036381064 scopus 로고    scopus 로고
    • Mechanism of induction of complement susceptibility of erythrocytes by spider and bacterial sphingomyelinases
    • Tambourgi D.V., Silva M.S., Billington S.J., Andrade R.M.G., Magnoli F.G., and Songer J.G. Mechanism of induction of complement susceptibility of erythrocytes by spider and bacterial sphingomyelinases. Immunology 107 (2002) 93-101
    • (2002) Immunology , vol.107 , pp. 93-101
    • Tambourgi, D.V.1    Silva, M.S.2    Billington, S.J.3    Andrade, R.M.G.4    Magnoli, F.G.5    Songer, J.G.6
  • 30
    • 0034598661 scopus 로고    scopus 로고
    • Comparison of enzymatic activity from three species of necrotising arachnids in Australia: Loxosceles rufescens, Badumma insignis and Lampona cylindrata
    • Young A.R., and Pincus S.J. Comparison of enzymatic activity from three species of necrotising arachnids in Australia: Loxosceles rufescens, Badumma insignis and Lampona cylindrata. Toxicon 39 (2001) 391-400
    • (2001) Toxicon , vol.39 , pp. 391-400
    • Young, A.R.1    Pincus, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.