Soluble glucocorticoid-induced tumor necrosis factor receptor stimulates osteoclastogenesis by down-regulation of osteoprotegerin in bone marrow stromal cells

Bone

Volumn 39, Issue 4, 2006, Pages 716-723

  Shin, Hyun Hee ^a   Kim, Soo Jin ^a   Kang, So Young ^a   Lee, Dong Sul ^a   Choi, Hye Seon ^a  

^a University of Ulsan   (South Korea)

Author keywords

Bone marrow stromal cells; GITRL; OPG; Osteoclastogenesis; sGITR

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID TUMOR NECROSIS FACTOR RECEPTOR; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MATURATION; CELL MATURATION; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; OSTEOCLAST; PROTEIN DOMAIN; PROTEIN EXPRESSION; STEADY STATE; STROMA CELL; STRUCTURAL HOMOLOGY; UPREGULATION;

ANIMALS; ANTIBODIES; BONE MARROW CELLS; CELL LINE; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; FLOW CYTOMETRY; GENE EXPRESSION; MICE; MICE, INBRED C57BL; OSTEOCLASTS; OSTEOPROTEGERIN; PROSTAGLANDINS E; RANK LIGAND; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STROMAL CELLS; TUMOR NECROSIS FACTORS;

EID: 33748159590     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.03.015     Document Type: Article

References (31)

1. Yasuda H., Shima N., Nakagawa N., Yamaguchi K., Kinosaki M., Mochizuki S., et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci U S A 95 (1998) 3597-3602
2. Simonet W.S., Lacey D.L., Dunstan C.R., Kelley M., Chang M.S., Luthy R., et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell 89 (1997) 309-319
3. Bucay N., Sarosi I., Dunstan C.R., Morony S., Tarpley J., Capparelli C., et al. Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 12 (1998) 1260-1268
4. Mizuno A., Amizuka N., Irie K., Murakami A., Fujise N., Kanno T., et al. Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin. Biochem Biophys Res Commun 247 (1998) 610-615
5. 2 in human bone marrow stroma cells. Biochem Biophys Res Commun 247 (1998) 338-341
6. Suda T., Takahashi N., Udagawa N., Jimi E., Gillespie M.T., and Martin T.J. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families. Endocr Rev 20 (1999) 345-357
7. Lee S.K., and Lorenzo J.A. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation. Endocrinology 140 (1999) 3552-3561
8. Nocentini G., Giunchi L., Ronshetti S., Krausz L.T., Bartoli A., Moraca R., et al. New family of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis. Proc Natl Acad Sci U S A 94 (1997) 6216-6221
9. Kwon B., Yu K.Y., Ni J., Yu G.L., Jang I.K., Kim Y.J., et al. Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand. J Biol Chem 274 (1999) 1929-1934
10. Shin H.H., Lee M.H., Kim S.K., Kwon B., and Choi H.S. Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage. FEBS Lett 54 (2002) 275-280
11. Kim J.D., Choi B.K., Bae J.S., Lee U.H., Han I.S., Lee H.W., et al. Cloning and characterization of GITR ligand. Genes Immun 4 (2003) 564-569
12. Shimizu J., Yamazaki S., Takahashi T., Ishida Y., and Sakaguchi S. Stimulation of CD4+CD25+ regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 3 (2003) 135-142
13. Mchugh R.S., Whitters M.J., Piccirillo C.A., Young D.A., Shevach E.M., Collins M., et al. CD4+CD25+ immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16 (2002) 311-323
14. Shin H.H., Kwon B., and Choi H.S. Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces COX-2 activity in murine macrophage Raw 264.7 cell. Cytokine 19 (2002) 187-192
15. Lee H.S., Shin H.H., Kwon B., and Choi H.S. Soluble glucocorticoid-induced tumor necrosis factor receptor increased MMP-9 activity in murine macrophage. J Cell Biochem 88 (2003) 1048-1056
16. Shin H.H., Kim S.J., Lee H.S., and Choi H.S. The soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) causes cell cycle arrest and apoptosis in murine macrophages. Biochem Biophys Res Commun 315 (2004) 24-32
17. Shin H.H., Kim S.K., Lee M.H., Suh J.H., Kwon B., and Choi H.S. Soluble glucocorticoid induced tumor necrosis factor receptor (sGITR) induces inflammation in mice. Exp Mol Med 35 (2003) 358-364
18. Croft M. Costimulation of T cells by OX40, 4-1BB, and CD27. Cytokine Growth Factor Rev 14 (2003) 265-273
19. Tropel P., Noel D., Platet N., Legrand P., Benabid A.L., and Berger F. Isolation and characterization of mesenchymal stem cells from adult mouse bone marrow. Exp Cell Res 295 (2004) 395-406
20. Jimi E., Nakamura I., Amano H., Taguchi Y., Tsurukai T., Tamura M., et al. Osteoclast function is activated by osteoblastic cells through a mechanism involving cell-to cell contact. Endocrinology 137 (1996) 2187-2190
21. Shin H.H., Kim S.J., Lee D.S., and Choi H.S. The soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) stimulates osteoclast differentiation in response to receptor activator of NF-κB Ligand (RANKL) in osteoclast cells. Bone 36 (2005) 832-839
22. Sakumura Y., Tanaka K., Suda M., Yasoda A., Natsui K., Tanaka I., et al. Crucial involvement of the EP4 subtype of prostaglandin E receptor in osteoclast formation by proinflammatory cytokines and lipopolysaccharide. J Bone Miner Res 15 (2000) 218-227
23. Brandstrom H., Bjorkman T., and Ljunggren O. Regulation of osteoprotegerin secretion from primary cultures of human bone marrow stroma cells. Biochem Biophys Res Commun 280 (2001) 831-835
24. Suzawa T., Miyaura C., Inada M., Maruyama T., Sugimoto Y., Ushikubi F., et al. The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs. Endocrinology 141 (2000) 1554-1559
25. Suda K., Udagawa N., Sato N., Takami M., Itoh K., Woo J.-T., et al. Suppression of osteoprotegerin expression by prostaglandin E2 is crucially involved in lipopolysaccharide-induced osteoclast formation. J Immunol 172 (2004) 2504-2510
26. Nocentini G., Ronshetti S., Bartoli A., Spinicelli S., Delfino D., Brunetti L., et al. Identification of three novel mRNA splice variants of GITR. Cell Death Differ 7 (2000) 408-410
27. Font J., Pallares L., Martorell J., Martinez E., Gava A., Vives J., et al. Elevated soluble CD27 levels in serum of patients with systemic lupus erythematosus. Clin Immunol Immunopathol 81 (1996) 239-243
28. Michel J., and Schwarz H. Expression of soluble CD137 correlates with activation induced cell death of lymphocytes. Cytokine 12 (2000) 742-746
29. Langstein J., Michel J., Fritsche J., Kreutz M., Anderson R., and Schwarz H. CD137, a number of TNF receptor family, induces monocyte activation via bi-directional signaling. J Immunol 160 (1998) 2488-2494
30. Saito K., Ohara N., Hotokezaka H., Fukumoto S., Yuhasa K., Naito M., et al. Infection-induced upregulation of the costimulatory molecule 4-1BB in osteoblastic cells and its inhibitory effect on M-CSF/RANKL-induced in vitro osteoclastogenesis. J Biol Chem 279 (2004) 13555-13563
31. Kim S.J., Shin H.H., Park S.Y., Lee D.S., Lee E.A., Cho S.D., et al. Induction of MMP-13 expression by soluble human glucocorticoid induced tumor necrosis factor receptor in fibroblast-like synovial cells. Osteoarthr Cartil 14 (2006) 146-153