Genotoxic evaluation of workers employed in pesticide production

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 609, Issue 1, 2006, Pages 74-80

  Sailaja, N ^a   Chandrasekhar, M ^a   Rekhadevi, P V ^a   Mahboob, M ^a   Rahman, M F ^a   Vuyyuri, Saleha B ^b   Danadevi, K ^a,c   Hussain, S A ^a   Grover, Paramjit ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DECCAN COLLEGE OF MEDICAL SCIENCES   (India)

Author keywords

Chromosomal aberrations; Genotoxicity; Micronucleus; Occupational exposure; Pesticides

Indexed keywords

MUTAGENIC AGENT; PESTICIDE;

ADULT; AGE DISTRIBUTION; ALCOHOL CONSUMPTION; ARTICLE; CHEEK MUCOSA; CHROMOSOME ABERRATION; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC DAMAGE; GENOTOXICITY; HUMAN; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; MICRONUCLEUS TEST; OCCUPATIONAL HAZARD; PRIORITY JOURNAL; SEX DIFFERENCE; SMOKING; SOMATIC CELL; TOXICITY TESTING; WORKER;

ADULT; ALCOHOL DRINKING; ANALYSIS OF VARIANCE; CHROMOSOME ABERRATIONS; COMET ASSAY; FEMALE; HUMANS; INDIA; LYMPHOCYTES; MALE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MOUTH MUCOSA; OCCUPATIONAL EXPOSURE; PESTICIDES; QUESTIONNAIRES; SMOKING;

EID: 33748141963     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.06.022     Document Type: Article

References (46)

1. Barthel E. Increased risk of lung cancer in pesticide-exposed male agricultural workers. J. Toxicol. Environ. Health 8 (1981) 1027-1040
2. Meinert R., Schuz J., Kaletsch U., Kaatsch P., and Michaelis J. Leukemia and non-Hodgkin's lymphoma in childhood and exposure to pesticides: results of a register-based case-control study in Germany. Am. J. Epidemiol. 151 (2000) 639-646
3. Ji B.T., Silverman D.T., Stewart P.A., Blair A., Swanson G.M., Baris D., Greenberg R.S., Hayes R.B., Brown L.M., Lillemoe K.D., Schoenberg J.B., Pottern L.M., Schwartz A.G., and Hoover R.N. Occupational exposure to pesticides and pancreatic cancer. Am. J. Ind. Med. 39 (2001) 92-99
4. Viel J.F., and Challier B. Bladder cancer among French farmers: does exposure to pesticides in vineyards play a part?. Occup. Environ. Med. 52 (1995) 587-592
5. Brown L.M., Blair A., Gibson R., Everett G.D., Cantor K.P., Schuman L.M., Burmeister L.F., Van Lier S.F., and Dick F. Pesticide exposures and other agricultural risk factors for leukemia among men in Iowa and Minnesota. Cancer Res. 50 (1990) 6585-6591
6. Blair A., Zahm S.H., Pearce N.E., Heinemann E.F., and Fraumeni J.F. Clues to cancer etiology from studies of farmers. Scand. J. Work Environ. Health 18 (1992) 209-215
7. Blair A., and Zahm S.H. Agricultural exposures and cancer. Environ. Health Perspect. 103 (1995) 205-208
8. Kassie F., Parzefall W., and Knasmuller S. Single cell gel electrophoresis assay: a new technique for human biomonitoring studies. Mutat. Res. 463 (2000) 13-31
9. Hulka B.S., Wilcosky T.C., and Griffith J.D. Biological Markers in Epidemiology (1990), Oxford University Press, New York
10. Legator M.S., and Au W.W. Application of integrated genetic monitoring: the optimal approach for detecting environmental carcinogens. Environ. Health Perspect. 102 (1994) 125-132
11. Paz-y-Mino C., Arevalo M., Sanchez M.E., and Leone P.E. Chromosome and DNA damage analysis in individuals occupationally exposed to pesticides with relation to genetic polymorphism for CYP 1A1 gene in Ecuador. Mutat. Res. 562 (2004) 77-89
12. Pasquini R., Scassellati-Sforzolini G., Angeli G., Fatigoni C., Monarca S., Beneventi L., DiGiulio A.M., and Bauleo F.A. Cytogenetic biomonitoring of pesticide exposed farmers in central Italy. J. Environ. Pathol. Toxicol. Oncol. 15 (1996) 29-39
13. Gomez-Arroyo S., Diaz-Sanchez Y., Meneses-Perez M.A., Villalobos-Pietrini R., and De Leon-Rodriguez J. Cytogenetic biomonitoring in a Mexican floriculture worker group exposed to pesticides. Mutat. Res. 466 (2000) 117-124
14. Scarpato R., Migliore L., Hirvonen A., Falck G., and Norppa H. Cytogenetic monitoring of occupational exposure to pesticides: characterization of GSTM1, GSTT1 and NAT2 genotypes. Environ. Mol. Mutagen. 27 (1996) 263-269
15. Marquez C., Villalobos C., Poblete S., Villalobos E., Garcia M.A., and Duk S. Cytogenetic damage in female Chilean agricultural workers exposed to mixtures of pesticides. Environ. Mol. Mutagen. 45 (2005) 1-7
16. Pastor S., Creus A., Parron T., Cebulska-Wasilewska A., Siffel C., Piperakis S., and Marcos R. Biomonitoring of four European populations occupationally exposed to pesticides: use of micronuclei as biomarkers. Mutagenesis 18 (2003) 249-258
17. Jablonika A., Polakova H., Karelova J., and Vargova M. Analysis of chromosome aberrations and sister-chromatid exchanges in peripheral blood lymphocytes of workers with occupational exposure to the mancozeb containing fungicide Novozir Mn80. Mutat. Res. 224 (1989) 143-146
18. Laurent C., Jadot P., and Chabut C. Unexpected decrease in cytogenetic biomarkers frequencies observed after increased exposure to organo-phosphorous pesticides in a production plant. Int. Arch. Occup. Environ. Health 68 (1996) 399-404
19. Kaioumova D.F., and Khabutdinova L.K. Cytogenetic characteristics of herbicide production workers in Ufa. Chemosphere 37 (1998) 1755-1759
20. Amr M.M. Pesticide monitoring and its health problems in Egypt: a third world country. Toxicol. Lett. 107 (1999) 1-13
21. Garaj-Vrhovac V., and Zeljezic D. Chromosomal aberrations and frequency of micronuclei in workers employed in pesticide production. Biologia 54 (1999) 707-712
22. Padmavati P., Prabhavathi P.A., and Reddy P.P. Frequencies of SCEs in peripheral blood lymphocytes of pesticide workers. Bull. Environ. Contam. Toxicol. 64 (2000) 155-160
23. Garaj-Vrhovac V., and Zeljezic D. Evaluation of DNA damage in workers occupationally exposed to pesticides using single-cell gel electrophoresis (SCGE) assay pesticide genotoxicity revealed by comet assay. Mutat. Res. 469 (2000) 279-285
24. Garaj-Vrhovac V., and Zeljezic D. Cytogenetic monitoring of Croatian population occupationally exposed to a complex mixture of pesticides. Toxicology 165 (2001) 153-162
25. Zeljezic D., and Garaj-Vrhovac V. Chromosomal aberrations and single cell gel electrophoresis (comet) assay in the longitudinal risk assessment of occupational exposure to pesticides. Mutagenesis 16 (2001) 359-363
26. Garaj-Vrhovac V., and Zeljezic D. Assessment of genome damage in a population of Croatian workers employed in pesticide production by chromosomal aberration analysis micronucleus assay and comet assay. J. Appl. Toxicol. (2002) 249-255
27. Zeljezic D., and Garaj-Vrhovac V. Sister chromatid exchange and proliferative rate index in the longitudinal risk assessment of occupational exposure to pesticides. Chemosphere 46 (2002) 295-303
28. Grover P., Danadevi K., Mahboob M., Rozati R., Banu B.S., and Rahman M.F. Evaluation of genetic damage in workers employed in pesticide production utilizing the comet assay. Mutagenesis 18 (2003) 201-205
29. Shadnia S., Azizi E., Hosseini R., Khoei S., Fouladdel S., Pajoumand A., Jalali N., and Abdollahi M. Evaluation of oxidative stress and genotoxicity in organophosphorus insecticide formulators. Hum. Exp. Toxicol. 24 (2005) 439-445
30. Rupa D.S., Reddy P.P., and Reddi O.S. Clastogenetic effect of pesticides in peripheral lymphocytes of cotton-field workers. Mutat. Res. 261 (1991) 177-180
31. Rahman M.F., Mahboob M., Danadevi K., Banu B.S., and Grover P. Assessment of genotoxic effects of chloropyriphos and acephate by the comet assay in mice leucocytes. Mutat. Res. 516 (2002) 139-147
32. Wang T.C., Lee T.C., Lin M.F., and Lin S.Y. Induction of sister-chromatid exchanges by pesticides in primary rat tracheal epithelial cells and Chinese hamster ovary cells. Mutat. Res. 188 (1987) 311-321
33. Jamil K., Shaik A.P., Mahboob M., and Krishna D. Effect of organophosphorus and organochlorine pesticides (monochrotophos, chloropyriphos, dimethoate, and endosulfan) on human lymphocytes in vitro. Drug Chem. Toxicol. 27 (2004) 133-144
34. Herrera A., and Laborda E. Mutagenic activity in synthetic pyrethroids in Salmonella typhimurium. Mutagenesis 3 (1988) 509-514
35. Giri S., Giri A., Sharma G.D., and Prasad S.B. Induction of sister chromatid exchanges by cypermethrin and carbosulfan in bone marrow cells of mice in vivo. Mutagenesis 18 (2003) 53-58
36. Vigreux C., Poul J.M., Deslandes E., Lebailly P., Godard T., Sichel F., Henry-Amar M., and Gauduchon P. DNA damaging effects of pesticides measured by the single cell gel electrophoresis assay (comet assay) and the chromosomal aberration test, in CHOKI cells. Mutat. Res. 419 (1998) 79-90
37. Koh D., and Jeyaratnam J. Pesticide hazards in developing countries. Sci. Total Environ. 188 (1996) 578-585
38. WHO, Control Technology for the Formulation and Packing of Pesticides, World Health Organisation, Geneva, 1992.
39. Carbonell E., Valbuena A., Xamena N., Creus A., and Marcos R. Temporary variations in chromosomal aberrations in a group of agricultural workers exposed to pesticides. Mutat. Res. 344 (1995) 127-134
40. Kaufman W.K. Pathways of human cell post-replication repair. Carcinogenesis 10 (1989) 1-11
41. Heddle J.A., Cimino M.C., Hayashi M., Romagna F., Shelby M.D., Tucker J.D., Vanparys P., and MacGregor J.T. Micronuclei as an index of cytogenetic damage: past present and future. Environ. Mol. Mutagen. 18 (1991) 277-291
42. Rosin M.P., and Gibert A.M. Modulation of genotoxic effects in human. In: Mendelsohn M.L., and Albertini R.J. (Eds). Mutation and Environment, Part E. Environmental Genotoxicity, Risk and Modulation (1990), Wiley-Liss, New York 351-360
43. Bolognesi C., Perrone E., and Landini E. Micronucleus monitoring of a floriculturist population from western Liguria, Italy. Mutagenesis 17 (2002) 391-397
44. Paz-y-Mino C., Bustamante G., Sanchez M.E., and Leone P.E. Cytogenetic monitoring in a population occupationally exposed to pesticides in Ecuador. Environ. Health Perspect. 110 (2002) 1077-1080
45. Pacheco A.O., and Hackel C. Chromosome instability induced by agrochemicals among farm workers in Passo Fundo, Rio Grande do Sul, Brazil. Cad Saude Publ. 18 (2002) 1675-1683
46. Undeger U., and Basaran N. Assessment of DNA damage in workers occupationally exposed to pesticide mixtures by alkaline comet assay. Arch. Toxicol. 76 (2002) 430-436