Cytotoxicity of a recombinant fusion protein of adenovirus early region 4 open reading frame 4 (E4orf4) and human epidermal growth factor on p53-deficient tumor cells

Anti-Cancer Drugs

Volumn 17, Issue 5, 2006, Pages 527-537

  Wang, Dong Mei ^a   Zhou, Yu ^a   Xie, Hai Jun ^a   Ma, Xiao Li ^a   Wang, Xin ^a   Chen, Hong ^a   Huang, Bing Ren ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Adenovirus E4orf4; Apoptosis; Cytotoxicity; Epidermal growth factor; Fusion protein; Selective targeting

Indexed keywords

ANTINEOPLASTIC AGENT; BROXURIDINE TRIPHOSPHATE; DNA FRAGMENT; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA UROGASTRONE ADENOVIRUS EARLY REGION 4 OPEN READING FRAME 4 PROTEIN; HYBRID PROTEIN; MARKER; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CANCER INHIBITION; CELL SURFACE; CELL TRANSPORT; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; DRUG CYTOTOXICITY; DRUG LABELING; DRUG MECHANISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; LONG TERM EXPOSURE; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN TARGETING; STATISTICAL SIGNIFICANCE; TUMOR CELL; TUMOR GROWTH;

CELL DEATH; CELL LINE, TUMOR; CELL NUCLEUS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDERMAL GROWTH FACTOR; FLOW CYTOMETRY; HUMANS; MICROSCOPY, CONFOCAL; NEOPLASMS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; TUMOR SUPPRESSOR PROTEIN P53; VIRAL PROTEINS;

EID: 33748126277     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reactfunctpolym.2005.10.005     Document Type: Article

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