Propofol metabolism is enhanced after repetitive ketamine administration in rats: The role of cytochrome P-450 2B induction

British Journal of Anaesthesia

Volumn 97, Issue 3, 2006, Pages 351-358

  Chan, W H ^a,b   Chen, T L ^c   Chen, R M ^c   Sun, W Z ^b   Ueng, T H ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Anaesthetics, i.v., ketamine; Anaesthetics, propofol; Drug drug interaction; i.v., enzymes, cytochrome P 450; Rat

Indexed keywords

CYTOCHROME P450 2B; KETAMINE; MESSENGER RNA; ORPHENADRINE; PENTOXYRESORUFIN DEALKYLASE; PROPOFOL;

ALKYLATION; ANESTHESIA INDUCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG INFUSION; DRUG METABOLISM; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME ANALYSIS; EX VIVO STUDY; IN VIVO STUDY; LIVER LEVEL; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RAT; RAT STRAIN; SLEEP TIME;

EID: 33748053024     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/ael173     Document Type: Article

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