Structural model of the membrane-bound C terminus of lipid-modified human N-ras protein

Angewandte Chemie - International Edition

Volumn 45, Issue 32, 2006, Pages 5387-5390

  Reuther, Guido ^a,c   Tan, Kui Thong ^b   Köhler, Julia ^c   Nowak, Christine ^b   Pampel, André ^c   Arnold, Klaus ^a,c   Kuhlmann, Jürgen ^b   Waldmann, Herbert ^b   Huster, Daniel ^a,c  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Membrane proteins; NMR spectroscopy; Ras proteins; Signal transduction

Indexed keywords

MEMBRANE PROTEINS; RAS PROTEINS; SIGNAL TRANSDUCTION;

BIOLOGICAL MEMBRANES; LIPIDS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SYNTHESIS (CHEMICAL); TORSIONAL STRESS;

PROTEINS;

LIPID; RAS PROTEIN;

ARTICLE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; PROTEIN CONFORMATION;

CELL MEMBRANE; HUMANS; LIPIDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RAS PROTEINS;

EID: 33747890325     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200504266     Document Type: Article

References (33)

1. Lipid Modification of Proteins (Ed.: M. J. Schlesinger), CRC, Boca Raton, 1993.
2. P. J. Casey, Science 1995, 268, 221-225.
3. D. Murray, N. Ben-Tal, B. Honig, S. McLaughlin, Structure 1997, 5, 985-989.
4. A. Wittinghofer, H. Waldmann, Angew. Chem. 2000, 112, 4360-4383;
5. Angew. Chem. Int. Ed. 2000, 39, 4192-4214.
6. a) M. V. Milburn, L. Tong, A. M. deVos, A. Brünger, Z. Yamaizumi, S. Nishimura, S. H. Kim, Science 1990, 247, 939-945;
7. b) E. F. Pai, W. Kabsch, U. Krengel, K. C. Holmes, J. John, A. Wittinghofer, Nature 1989, 341, 209-214.
8. a) P. J. Kraulis, P. J. Domaille, S. L. Campbell-Burk, T. Van Aken, E. D. Laue, Biochemistry 1994, 33, 3515-3531;
9. b) R. Thapar, J. G. Williams, S. L. Campbell, J. Mol. Biol. 2004, 343, 1391-1408.
10. T. Dudler, M. H. Gelb, J. Biol. Chem. 1996, 271, 11 541-11 547.
11. R. G. Parton, J. F. Hancock, Trends Cell Biol. 2004, 14, 141-147.
12. B. Bader, K. Kuhn, D. J. Owen, H. Waldmann, A. Wittinghofer, J. Kuhlmann, Nature 2000, 403, 223-226.
13. a) J. Torres, T. J. Stevens, M. Samso, Trends Biochem. Sci. 2003, 28, 137-144;
14. b) S. Luca, H. Heise, A. Lange, M. Baldus, Arch. Pharm. 2005, 338, 217-228;
15. c) D. Huster, Prog. Nucl. Magn. Reson. Spectrosc. 2005, 46, 79-107.
16. M. Volkert, K. Uwai, A. Tebbe, B. Popkirova, M. Wagner, J. Kuhlmann, H. Waldmann, J. Am. Chem. Soc. 2003, 125, 12 749-12 758.
17. C. W. Lee, R. G. Griffin, Biophys. J. 1989, 55, 355-358.
18. N. M. Szeverenyi, M. J. Sullivan, G. E. Maciel, J. Magn. Reson. 1982, 47, 462-475.
19. a) D. S. Wishart, B. D. Sykes, Methods Enzymol. 1994, 239, 363-392;
20. b) S. Spera, A. Bax, J. Am. Chem. Soc. 1991, 113, 5490-5492;
21. c) H. Saitô, Magn. Reson. Chem. 1986, 24, 835-852.
22. G. Cornilescu, F. Delaglio, A. Bax, J. Biomol. NMR 1999, 13, 289-302.
23. a) S. Luca, J. F. White, A. K. Sohal, D. V. Filippov, J. H. van Boom, R. Grisshammer, M. Baldus, Proc. Natl. Acad. Sci. USA 2003, 100, 10 706-10 711;
24. b) A. T. Petkova, Y. Ishii, J. J. Balbach, O. N. Antzutkin, R. D. Leapman, F. Delaglio, R. Tycko, Proc. Natl. Acad. Sci. USA 2002, 99, 16 742-16 747;
25. c) S. Sharpe, W.-M. Yau, R. Tycko, Biochemistry 2006, 45, 918-933.
26. S. K. Sarkar, T. D. Kopple, D. L. VanderHart, J. Am. Chem. Soc. 1984, 106, 3328-3331.
27. R. Koradi, M. Billeter, K. Wüthrich, J. Mol. Graphics 1996, 14, 51-55.
28. a) D. Huster, A. Vogel, C. Katzka, H. A. Scheldt, H. Binder, S. Dante, T. Gutberlet, O. Zschörnig, H. Waldmann, K. Arnold, J. Am. Chem. Soc. 2003, 125, 4070-4079;
29. b) D. Huster, K. Kuhn, D. Kadereit, H. Waldmann, K. Arnold, Angew. Chem. 2001, 113, 1083-1085;
30. Angew. Chem. Int. Ed. 2001, 40, 1056-1058.
31. W. C. Wimley, S. H. White, Nat. Struct. Biol. 1996, 3, 842-848.
32. C. R. Morcombe, K. W. Zilm, J. Magn. Reson. 2003, 162, 479-486.
33. G. Kontaxis, F. Delaglio, A. Bax, Methods Enzymol. 2005, 394, 42-78.